Organ-on-a-chip for drug testing in brain diseases

MicroTAS 2015 - 19th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Volumn , Issue , 2015, Pages 161-163

  Xu, H ^a   Zhang, M ^a   Wang, L ^a   Qin, J H ^a  

^a DALIAN INSTITUTE OF CHEMICAL PHYSICS   (China)

Author keywords

Blood brain barrier; Drug testing; Organ on a chip

Indexed keywords

BIOMIMETICS; BLOOD;

ANIMAL MODEL; BLOOD-BRAIN BARRIER; BRAIN DISEASE; DRUG TESTING; MICROFLUIDIC-BASED; ORGAN-ON-A-CHIP; PREDICTIVE ABILITIES; THERAPEUTIC APPLICATION;

PHYSIOLOGY;

EID: 84983315906     PISSN: None     EISSN: None     Source Type: Conference Proceeding    
DOI: None     Document Type: Conference Paper

References (3)

1. Maxime. Culot, S. Lundquist, D. Vanuxeem, etc. "An in vitro blood-brain barrier model for high throughput (HTS) toxicological screening", Toxicology in Vitro, 22, 799-811, 2008.
2. A. Patabendige, Robert A. Skinner, N.J. Abbott. "Establishment of a simplified in vitro porcine blood-brain barrier model with high transendothelial electrical resistance", Brain Research, 1521, 1-15, 2013.
3. H. Xu, S. Rahimpour, C.L. Nesvick, X. Zhang, J. etc., "Activation of hypoxia signaling induces phenotypic transformation of glioma cells: implications for bevacizumab antiangiogenic therapy", Oncotarget, 6, 11882-93, 2015