Structural Effects of Some Relevant Missense Mutations on the MECP2-DNA Binding: A MD Study Analyzed by Rescore+, a Versatile Rescoring Tool of the VEGA ZZ Program

Molecular Informatics

Volumn , Issue , 2016, Pages 424-433

  Pedretti, Alessandro ^a   Granito, Cinzia ^a   Mazzolari, Angelica ^a   Vistoli, Giulio ^a  

^a UNIVERSITY OF MILAN   (Italy)

Author keywords

DNA binding; MECP2; missense mutations; molecular dynamics; rescoring tool

Indexed keywords

ALKYLATION; BIOINFORMATICS; DNA; MAMMALS; MOLECULAR DYNAMICS;

DNA METHYLATION; DNA-BINDING; MAMMALIAN CELLS; MD SIMULATION; MECP2; MENTAL RETARDATION; MISSENSE MUTATION; RESCORING TOOL; RETT SYNDROME; STRUCTURAL EFFECT;

PROTEINS;

METHYL CPG BINDING PROTEIN 2; MUTANT PROTEIN;

ARTICLE; COMPUTER PROGRAM; CONTROLLED STUDY; DATA BASE; MISSENSE MUTATION; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN DNA INTERACTION; PROTEIN FOLDING; PROTEIN STRUCTURE; SIMULATION; WILD TYPE;

EID: 84983252350     PISSN: 18681743     EISSN: 18681751     Source Type: Journal    
DOI: 10.1002/minf.201501030     Document Type: Article

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