The role of natural killer cells in pathogenesis of autoimmune diseases

Central European Journal of Immunology

Volumn 40, Issue 4, 2015, Pages 470-476

  Popko, Katarzyna ^a   Górska, Elzbieta ^a  

^a MEDICAL UNIVERSITY OF WARSAW   (Poland)

Author keywords

Autoimmune reaction; Hashimoto thyroiditis; Juvenile rheumatoid arthritis; NK cells; Type 1 diabetes

Indexed keywords

ARTICLE; AUTOIMMUNE DISEASE; AUTOIMMUNE THYROIDITIS; AUTOIMMUNITY; B LYMPHOCYTE; CYTOTOXICITY; EARLY DIAGNOSIS; HASHIMOTO DISEASE; HEMOPHAGOCYTIC LYMPHOCYTOSIS; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; JUVENILE RHEUMATOID ARTHRITIS; LYMPHOCYTOSIS; MACROPHAGE ACTIVATION SYNDROME; NATURAL KILLER CELL; NONHUMAN; PATHOGENESIS; T LYMPHOCYTE;

EID: 84983179861     PISSN: 14263912     EISSN: 16444124     Source Type: Journal    
DOI: 10.5114/ceji.2015.56971     Document Type: Article

References (62)

1. Freud AG, Becknell B, Roychowdhury S, et al. (2005): A human CD34(+) subset resides in lymph nodes and differentiates into CD56bright natural killer cells. Immunity 22: 295-304.
2. Andrews DM, Smyth MJ (2010): A potential role of RAG-1 in NK cell development revealed by analysis of NK cells during ontogeny. Immunol Cell Biol 88: 107-116.
3. Ma A, Koka R, Burkett P (2006): Diverse functions of IL-2, IL-15 and IL-7 in lymphoid homeostasis. Annu Rev Immunol 24: 657-679.
4. Ashouri E, Dabbaghmanesh MH, Omrani GR, et al. (2014): Presence of more activating KIR genes is associated with Hashimoto's thyroiditis. Endocrine 46: 519-525.
5. Vilches C, Parham P (2002): KIR: diverse, rapidly evolving receptors of innate and adaptive immunity. Annu Rev Immunol 20: 217-251.
6. Mandal A, Viswanathan C (2015): Natural killers: In health and disease. Hematol Oncol Stem Cell Ther 8: 47-55.
7. Bryceson YT, March ME, Ljunggren H-G, et al. (2006): Synergy among receptors on resting NK cells for the activation of natural cytotoxicity and cytokine secretion. Blood 107: 159-166.
8. Colonna M, Navarro F, Bellón T, et al. (1997): A common inhibitoryreceptor for major histocompatibility complex class I molecules on human lymphoid and myelomonocytic cells. J Exp Med 186: 1809-1818.
9. Osinska I, Popko K, Demkow U (2014): Perforin: an important player in immune response. Centr Eur J Immunol 39: 109-115.
10. Trapani JA, Smyth MJ (2002): Functional significance of the perforin/granzyme cell death pathway. Nature Review Immunol 2: 735-747.
11. Voskoboinik I, Dunstone MA, Baran K, et al. (2010): Perfo-rin: structure, function, and role in human immunopathology. Immunol Rev 235: 35-54.
12. Cooper MA, Fehniger TA, Caligiuri MA (2001): The biology of human natural killer-cell subset. Trends Immunol 11: 633-640.
13. Cooper MA, Fehniger TA, Turner SC, et al. (2001): Human natural killer cells: a unique innate immunoregulatory role for the CD56brightsubset. Blood 97: 3146-3151.
14. Wilk E, Kallipke K, Buyny S, et al. (2008): New aspects of NK cell subset identification and inference of NK cells' regulatory capacity by assessing functional and genomic profiles. Immunobiology 213: 271-283.
15. Sinkonics JG, Horvath JC (2005): Human natural killer cells: a comprehensive revive. Int J Oncol 27: 5-47.
16. French AR, Yokoyama WM (2004): Natural killer cells and autoimmunity. Arthritis Res Ther 6: 8-14.
17. Morse RH, Seguin R, McCrea EL, et al. (2001): NK cell-mediated lysis of autologous human oligodendrocytes. J Neuro-immunol 116: 107-115.
18. Flodstrom M, Maday A, Balakrishna D, et al. (2002): Target cell defense prevents the development of diabetes after viral infection. Nat Immunol 3: 373-382.
19. Linsen L, Somers V, Stinissen P (2005): Immunoregulation of autoimmunity by natural killer T cells. Human Immunology 66: 1193-1202.
20. Fairweather D, Kaya Z, Shellam GR, et al. (2001): From infection to autoimmunity. J Autoimmun 16: 175-186.
21. Augusto DG, Lobo-Alves SC, Melo MF, et al. (2012): Acti-vating KIR and HLA Bw4 ligands are associated to decreased susceptibility to pemphigus foliaceus, an autoimmune blister-ing skin disease. PLoS ONE 7(7): e39991.
22. HaiQing Z, JiaJun Z, YueRan Z, et al. (2009): Genotypes of killer cell immunoglobulin-like receptors in Hashimoto's thyroiditis patients. Journal of Shandong University (Health Sciences) 47: 1-4.
23. van der Slik AR, Alizadeh BZ, Koeleman BP, et al. (2007): Modelling KIR-HLA genotype disparities in type 1 diabetes. Tissue Antigens 69 (Suppl 1): 101-105.
24. Niepiekło-Miniewska W, Majorczyk E, Matusiak L, et al. (2013): Protective effect of the KIR2DS1 gene in atopic der-matitis. Gene 527: 594-600.
25. Hou Y-F, Zhang Y-C, Jiao Y-L, et al. (2010): Disparate distribution of activating and inhibitory killer cell immuno-globulin-like receptor genes in patients with systemic lupus erythematosus. Lupus 19: 20-26.
26. García-León JA, Pinto-Medel MJ, García-Trujillo L, et al. (2011): Killer cell immunoglobulin-like receptor genes in Spanish multiple sclerosis patients. Mol Immunol 48: 1896-1902.
27. Gujónsson JE, Karason A, Antonsdottir AA, et al. (2002): HLA-Cw6-positiv and HLA-Cw6-negative patients with psoriasis vulgaris have distinct clinical features. J Invest Derma-tol 118: 362-365.
28. Rodacki M, MIlech A, de Olivejra JEP, (2006): NK cell land Type 1 diabetes. Clin Dev Immunol 13: 101-107.
29. Janeway CA, Trawers P, Walport M (2005): An introduction to immunobiology and innate immunity. NY Ed Garland Sci-ence Publishing. P. 1-35.
30. Dalbeth N, Callan MFC (2002): A subset of natural killer cells is greatly expanded within inflamed joints. Arthritis Reum 46: 1763-1772.
31. Pridgeon C, Lennon GP, Pazmany L, et al. (2003): Natural killer cells in the synovial fluid of rheumatoid arthritis patients exhibit CD56bright, CD94bright, CD158negative phe-notype. Rheumatology 42: 870-878.
32. de Matos CT, Berg L, Michaelsson J, et al. (2007): Activating and inhibitory receptors on synovial fluid natural killer cells of arthritis patients: role of CD94/NKG2A in control of cyto-kine secretion. Immunology 122: 291-301.
33. Zhang AL, Colmenero P, Purath U, et al. (2007): Natural killer cells trigger differentiation of monocytes into dendritic cells. Blood 110: 2484-2493.
34. Ren J, Feng Z, Lv Z, et al. (2011): Naturak killer-22 cells in the synovial fluid of patients with rheumatoid arthritis are an innate source of interleukin 22 and tumor necrosis factor-α. J Reumatol 38: 2112-2118.
35. Grog V, Bruhl A, El-Gabalawy H, et al. (2003): Stimulation of T cell autoreactivity by anomalous expression of NKG2D and its MIC ligands in rheumatoid artritis. Proc Natl Acad Sci USA 100: 9452-9457.
36. Fogel L, Yokoyama WM, French AR (2013): Natural killer cells in human autoimmune disorders. Arthitis Res Ther 15: 216-224.
37. Aramaki T, Ida H, Izumi Y, et al. (2009): Significantly impaired natural cell activity due to a low activity on a per-cell basis in rheumatoid arthritis. Mod Rheumatol 19: 245-252.
38. Wulffraat NM, Rijekers GT, Elst E, et al. (2003): Reduced perforin expression in systemic juvenile idiopathic arthritis is restores by autologous stem-cell transplantation. Rheumatology 42: 375-379.
39. Grom AA, Villanueva J, Lee S, et al. (2003): Natural killer cell dysfunction in patients with systemic-onset juvenile rheumatoid arthritis and macrophage activation syndrome. J Pediatr 142: 292-296.
40. Villanueva J, Lee S, Giannini EH, et al. (2005): Natural killer cell dysfunction is a distinguishing feature of systyemic onset juvenile rheumatoid arthritis and macrophage activation syndrome. Arthritis Res Ther 7: R30-37.
41. Behrens EM (2008): Macrophage activation syndrome in rheumatic disease: What is the role of the antigen presenting cell? Autoimmun Rev 7: 305-308.
42. Anjos S, Polychronakos C (2004): Mechanisms of genetic susceptibility to 1 diabetic: beyond HLH. Mol Genet Metab 81: 357-395.
43. Robles DT, Eisenbarth GS, (2001): Type 1A diabetes induced by infection and immunization. J Autoimmun 16355-16362.
44. Wu YL, Ding YP, Gao Y (2013): Risk factors and primary prevention trials for type 1 diabetes. Int J Biol Sci 9: 666-679.
45. Akerblom HK, Vaarala O, Hyoty H, et al. (2002): Environmental factors in the etiology of type 1 diabetes. Am J Med Genet 115: 18-29.
46. Hussain MJ, Alviggi L, Millward BA, et al. (1987): Evidence that the reduced number of natural killer cells in type 1 diabetes may be genetically determined. Diabetologia 30: 907-911.
47. Vanderpump MP, Tunbridge WM (2002): Epidemiology and prevention of clinical and subclinical hypothyroidism. Thy-roid 12: 839-847.
48. Wang C, Crapo LM (1997): The epidemiology of thyroid disease and implications for screening. Endocrinol Metab Clin North Am 26: 189-218.
49. Hueston WJ, (2001): Treatment of hypothyroidism. Am Fam Physician 64: 1717-1724.
50. Jenkins RC, Weetman AP (2002): Disease associations with autoimmune thyroid disease. Thyroid 12: 977-988.
51. Kabel PJ, Voorbij HA, de Haan M, et al. (1988): Intarthy-roidal dendritic cells. J Clin Endocrinol Metab 66: 199-207.
52. Weetman AP (2003): Autoimmune thyroid disease: propagation and progression. Eur J Endocrinol 148: 1-9.
53. Michels AW, Eisenbatrh GS (2010): Immunologic endocrine disorders. J Allergy Clin Immunol 125 (Supp. 2): 226-237.
54. Popko K, Osinska A, Kucharska A, Demkow U (2015): Cyto-metric analysis of perforin expression in NK cells, CD8+, and CD4+ lymphocytes in children with autoimmune Hashimoto's thyroiditis-a preliminary study. J Pediatr Endocrinol Metab 28: 789-792.
55. Baxter AG, Smyth NJ (2002): The role of NK cells in autoimmune disease. Autoimmunity 35: 1-14.
56. Wencel B, Chow A, Schleusener H (1981): NK cell activity in autoimmune thyroid disorders. Proceedings of the 56th Annual Meeting of the American Thyroid Association Minneapolis Abstract T26.
57. Lackner H, Urban C, Sovinz P, et al. (2008): Hemophagocytic lymphohistiocytosis as severe adverse event of antineoplastic treatment in children. Haematologica 93: 291-294.
58. Fishman DN (2000): Hemophagocytic syndromes and infection. Emerging Infectious Diseases 6: 601-608.
59. Henter JI, Horne AC, Arico M (2007): for the Histiocyte Society. Reviev HLH-2004: Diagnostic and therapeutic guidelines for Hemophagocytic Lymphohistiocytosis. Pediatr Blood Cancer 48: 124-131.
60. Horne AC, Goransdotter Ramme K, Zheng C, et al. (2008): Charakterization of PRF1, STX1 and UNC13D genotype-phe-notype correlations in familial hemophagocytic lymphohistio-cytosis. Br J Haematol 143: 75-83.
61. Vastert SJ, van Wijk R, D'Urbano LE (2009): Mutations in the perforin gene can be linked to macrophage activation syndrome in patients with systemic onset juvenile idiopathic arthritis. Rheumatology 49: 441-449.
62. Grom AA (2004): Natural killer cell dysfunction: A common pathway in systemic-onset juvenile rheumatoid arthritis, mac-rophage activation syndrome, and hemophagocytic lympho-histiocytosis? Arthritis Rheum 50: 689-698.