-
1
-
-
84858013655
-
Management of advanced gastric cancer
-
Price TJ, Shaprio JD, Segelov E, Karapetis CS, Pavlakis N, Van Cutsem E, Shah MA, Kang YK, Tebbutt NC. Management of advanced gastric cancer. Expert Rev Gastroenterol Hepatol. 2012; 6:199-208. doi: 10.1586/egh.11.103.
-
(2012)
Expert Rev Gastroenterol Hepatol
, vol.6
, pp. 199-208
-
-
Price, T.J.1
Shaprio, J.D.2
Segelov, E.3
Karapetis, C.S.4
Pavlakis, N.5
Van Cutsem, E.6
Shah, M.A.7
Kang, Y.K.8
Tebbutt, N.C.9
-
2
-
-
84858766182
-
The blockade of immune checkpoints in cancer immunotherapy
-
Pardoll DM. The blockade of immune checkpoints in cancer immunotherapy. Nat Rev Cancer. 2012; 12:252-64. doi: 10.1038/nrc3239.
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 252-264
-
-
Pardoll, D.M.1
-
3
-
-
0034596948
-
Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation
-
Freeman GJ, Long AJ, Iwai Y, Bourque K, Chernova T, Nishimura H, Fitz LJ, Malenkovich N, Okazaki T, Byrne MC, Horton HF, Fouser L, Carter L, et al. Engagement of the PD-1 immunoinhibitory receptor by a novel B7 family member leads to negative regulation of lymphocyte activation. J Exp Med. 2000; 192:1027-34. doi: 10.1084/jem.192.7.1027.
-
(2000)
J Exp Med
, vol.192
, pp. 1027-1034
-
-
Freeman, G.J.1
Long, A.J.2
Iwai, Y.3
Bourque, K.4
Chernova, T.5
Nishimura, H.6
Fitz, L.J.7
Malenkovich, N.8
Okazaki, T.9
Byrne, M.C.10
Horton, H.F.11
Fouser, L.12
Carter, L.13
-
4
-
-
84874869077
-
Antagonist antibodies to PD-1 and B7-H1 (PD-L1) in the treatment of advanced human cancer
-
Sznol M, Chen L. Antagonist antibodies to PD-1 and B7-H1 (PD-L1) in the treatment of advanced human cancer. Clin Cancer Res. 2013; 19:1021-34. doi: 10.1158/1078-0432.CCR-12-2063.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 1021-1034
-
-
Sznol, M.1
Chen, L.2
-
5
-
-
84875463042
-
Molecular mechanisms of T cell co-simulation and co-inhibition
-
Chen L, Flies DB. Molecular mechanisms of T cell co-simulation and co-inhibition. Nat Rev Immunol. 2013; 13:227-42. doi:10.1038/nri3405.
-
(2013)
Nat Rev Immunol
, vol.13
, pp. 227-242
-
-
Chen, L.1
Flies, D.B.2
-
6
-
-
84862903106
-
Safety and activity of anti-PD-L1 antibody in patients with advanced cancer
-
Brahmer JR, Tykodi SS, Chow LQ, Hwu WJ, Topalian SL, Hwu P, Drake CG, Camacho LH, Kauh J, Odunsi K, Pitot HC, Hamid O, Bhatia S, et al. Safety and activity of anti-PD-L1 antibody in patients with advanced cancer. New Engl J Med. 2012; 366:2455-65. doi: 10.1056/NEJMoa1200694.
-
(2012)
New Engl J Med
, vol.366
, pp. 2455-2465
-
-
Brahmer, J.R.1
Tykodi, S.S.2
Chow, L.Q.3
Hwu, W.J.4
Topalian, S.L.5
Hwu, P.6
Drake, C.G.7
Camacho, L.H.8
Kauh, J.9
Odunsi, K.10
Pitot, H.C.11
Hamid, O.12
Bhatia, S.13
-
7
-
-
84900430387
-
Harnessing the power of the immune system via blockade of PD-1 and PD-L1: a promising new anticancer strategy
-
Reiss KA, Forde PM, Brahmer JR. Harnessing the power of the immune system via blockade of PD-1 and PD-L1: a promising new anticancer strategy. Immunotherapy. 2014; 6:459-75. doi: 10.2217/imt.14.9.
-
(2014)
Immunotherapy
, vol.6
, pp. 459-475
-
-
Reiss, K.A.1
Forde, P.M.2
Brahmer, J.R.3
-
8
-
-
77950283280
-
Tumor cell expression of programmed cell death-1 ligand 1 is a prognostic factor for malignant melanoma
-
Hino R, Kabashima K, Kato Y, Yagi H, Nakamura M, Honjo T, Okazaki T, Tokura Y. Tumor cell expression of programmed cell death-1 ligand 1 is a prognostic factor for malignant melanoma. Cancer. 2010; 116:1757-66. doi: 10.1002/cncr.24899.
-
(2010)
Cancer
, vol.116
, pp. 1757-1766
-
-
Hino, R.1
Kabashima, K.2
Kato, Y.3
Yagi, H.4
Nakamura, M.5
Honjo, T.6
Okazaki, T.7
Tokura, Y.8
-
9
-
-
84922471654
-
Therapeutic uses of anti-PD-1 and anti-PD-L1 antibodies
-
Philips GK, Atkins M. Therapeutic uses of anti-PD-1 and anti-PD-L1 antibodies. International Immunology. 2015; 27:39-46. doi: 10.1093/intimm/dxu095.
-
(2015)
International Immunology
, vol.27
, pp. 39-46
-
-
Philips, G.K.1
Atkins, M.2
-
10
-
-
84890888514
-
Targeting the PD-1/PD-L1 axis in melanoma: biological rationale, clinical challenges and opportunities
-
Merelli B, Massi D, Cattaneo L, Mandata M. Targeting the PD-1/PD-L1 axis in melanoma: biological rationale, clinical challenges and opportunities. Crit Rev Oncol Hematol. 2014; 89:140-65. doi: 10.1016/j.critrevonc.2013.08.002
-
(2014)
Crit Rev Oncol Hematol
, vol.89
, pp. 140-165
-
-
Merelli, B.1
Massi, D.2
Cattaneo, L.3
Mandata, M.4
-
11
-
-
79955518331
-
Overall survival and PD-L1 expression in metastasized malignant melanoma
-
Gadiot J, Hooijkaas AI, Kaiser AD, van Tinteren H, van Boven H, Blank C. Overall survival and PD-L1 expression in metastasized malignant melanoma. Cancer. 2010; 117:2192-201. doi: 10.1002/cncr.25747.
-
(2010)
Cancer
, vol.117
, pp. 2192-2201
-
-
Gadiot, J.1
Hooijkaas, A.I.2
Kaiser, A.D.3
van Tinteren, H.4
van Boven, H.5
Blank, C.6
-
12
-
-
84901044976
-
In situ tumor PD-L1 mRNA expression is associated with increased TILs and better outcome in breast carcinoma
-
Schalper KA, Velcheti V, Carvajal D, Wimberly H, Brown J, Pusztai L, Rimm DL. In situ tumor PD-L1 mRNA expression is associated with increased TILs and better outcome in breast carcinoma. Clin Cancer Res. 2014; 20:2773-82. doi: 10.1158/1078-0432.CCR-13-2702.
-
(2014)
Clin Cancer Res
, vol.20
, pp. 2773-2782
-
-
Schalper, K.A.1
Velcheti, V.2
Carvajal, D.3
Wimberly, H.4
Brown, J.5
Pusztai, L.6
Rimm, D.L.7
-
13
-
-
84891534246
-
Programmed death ligand-1 expression in non-small cell lung cancer
-
Velcheti V, Schalper KA, Carvajal DE, Anagnostou VK, Syrigos KN, Sznol M, Herbst RS, Gettinger SN, Chen L, Rimm DL. Programmed death ligand-1 expression in non-small cell lung cancer. Lab Invest. 2014; 94:107-16. doi: 10.1038/labinvest.2013.130.
-
(2014)
Lab Invest
, vol.94
, pp. 107-116
-
-
Velcheti, V.1
Schalper, K.A.2
Carvajal, D.E.3
Anagnostou, V.K.4
Syrigos, K.N.5
Sznol, M.6
Herbst, R.S.7
Gettinger, S.N.8
Chen, L.9
Rimm, D.L.10
-
14
-
-
84937041504
-
Relationship between PD-L1 expression and clinical outcomes in patients(Pts) with advanced gastric cancer treated with the anti-PD-1 monoclonal antibody pembrolizumab (Pembro: MK-3475) in KEYNOTE-012
-
abstr 3
-
Muro K, Bang Y-J, Shankaran V, Geva R, Virgil D, Catenacci T, Gupta S, Eder JP, Berger R, Gonzalez EJ, Ray A, Dolled-Filhart M, Emancipator K, et al. Relationship between PD-L1 expression and clinical outcomes in patients(Pts) with advanced gastric cancer treated with the anti-PD-1 monoclonal antibody pembrolizumab (Pembro: MK-3475) in KEYNOTE-012. J Clin Oncol. 2015(suppl 3, abstr 3).
-
(2015)
J Clin Oncol
-
-
Muro, K.1
Bang, Y.-J.2
Shankaran, V.3
Geva, R.4
Virgil, D.5
Catenacci, T.6
Gupta, S.7
Eder, J.P.8
Berger, R.9
Gonzalez, E.J.10
Ray, A.11
Dolled-Filhart, M.12
Emancipator, K.13
-
15
-
-
44249092320
-
Assessment of a HER2 scoring system for gastric cancer: results from a validation study
-
Hofmann M, Stoss O, Shi D, Büttner R, van de Vijver M, Kim W, Ochiai A, Rüschoff J, Henkel T. Assessment of a HER2 scoring system for gastric cancer: results from a validation study. Histopathology, 2008; 52:797-805. doi: 10.1111/j.1365-2559.2008.03028.x.
-
(2008)
Histopathology
, vol.52
, pp. 797-805
-
-
Hofmann, M.1
Stoss, O.2
Shi, D.3
Büttner, R.4
van de Vijver, M.5
Kim, W.6
Ochiai, A.7
Rüschoff, J.8
Henkel, T.9
-
17
-
-
84905995225
-
Blockade of the B7-H1/PD-1 pathway as a basis for combination anticancer therapy
-
Sznol M. Blockade of the B7-H1/PD-1 pathway as a basis for combination anticancer therapy. Cancer J. 2014; 20:290-5. doi: 10.1097/PPO.0000000000000056.
-
(2014)
Cancer J
, vol.20
, pp. 290-295
-
-
Sznol, M.1
-
18
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
Topalian SL, Hodi FS, Brahmer JR, Gettinger SN, Smith DC, McDermott DF, Powderly JD, Carvajal RD, Sosman JA, Atkins MB, Leming PD, Spigel DR, Antonia SJ, et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med. 2012; 366:2443-54.
-
(2012)
N Engl J Med
, vol.366
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
Gettinger, S.N.4
Smith, D.C.5
McDermott, D.F.6
Powderly, J.D.7
Carvajal, R.D.8
Sosman, J.A.9
Atkins, M.B.10
Leming, P.D.11
Spigel, D.R.12
Antonia, S.J.13
-
19
-
-
84936147067
-
Combined Nivolumab and Ipilimumab or monotherapy in Untreated melanoma
-
Larkin J, Chiarion-Sileni V, Gonzalez R, Grob JJ, Cowey CL, Lao CD, Schadendorf D, Dummer R, Smylie M, Rutkowski P, Ferrucci PF, Hill A, Wagstaff J, etal. Combined Nivolumab and Ipilimumab or monotherapy in Untreated melanoma. N Engl J Med. 2015; 373:23-34. doi: 10.1056/NEJMoa1504030.
-
(2015)
N Engl J Med
, vol.373
, pp. 23-34
-
-
Larkin, J.1
Chiarion-Sileni, V.2
Gonzalez, R.3
Grob, J.J.4
Cowey, C.L.5
Lao, C.D.6
Schadendorf, D.7
Dummer, R.8
Smylie, M.9
Rutkowski, P.10
Ferrucci, P.F.11
Hill, A.12
Wagstaff, J.13
-
20
-
-
84864956021
-
HER2 status determination using RNA-ISH-a rapid and simple technique showing high correlation with FISH and IHC in 141 cases of breast cancer
-
Alba J, Gutierrez J, Coupe VM, Fernández B, VázquezBoquete Á, Alba J, Forteza J, García-Caballero T. HER2 status determination using RNA-ISH-a rapid and simple technique showing high correlation with FISH and IHC in 141 cases of breast cancer. Histol Histopathol. 2012; 27:1021-7.
-
(2012)
Histol Histopathol
, vol.27
, pp. 1021-1027
-
-
Alba, J.1
Gutierrez, J.2
Coupe, V.M.3
Fernández, B.4
VázquezBoquete, Á5
Alba, J.6
Forteza, J.7
García-Caballero, T.8
-
21
-
-
84923094572
-
Upregulation of PD-L1 and APEI is associated with tumorigenesis and poor prognosis of gastric cancer
-
Qing Y, Li Q, Ren T, Xia W, Peng Y, Liu GL, Luo H, Yang YX, Dai XY, Zhou SF, Wang D. Upregulation of PD-L1 and APEI is associated with tumorigenesis and poor prognosis of gastric cancer. Drug Des Devel Ther. 2015; 9:901-9. doi: 10.2147/DDDT.S75152.
-
(2015)
Drug Des Devel Ther
, vol.9
, pp. 901-909
-
-
Qing, Y.1
Li, Q.2
Ren, T.3
Xia, W.4
Peng, Y.5
Liu, G.L.6
Luo, H.7
Yang, Y.X.8
Dai, X.Y.9
Zhou, S.F.10
Wang, D.11
-
22
-
-
61549122071
-
Overexpression of PD-L1 significantly associates with tumor aggressiveness and postoperative recurrence in human hepatocellular carcinoma
-
Gao Q, Wang XY, Qiu SJ, Yamato I, Sho M, Nakajima Y, Zhou J, Li BZ, Shi YH, Xiao YS, Xu Y, Fan J. Overexpression of PD-L1 significantly associates with tumor aggressiveness and postoperative recurrence in human hepatocellular carcinoma. Clin Cancer Res. 2009; 15:971-9. doi: 10.1158/1078-0432.CCR-08-1608.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 971-979
-
-
Gao, Q.1
Wang, X.Y.2
Qiu, S.J.3
Yamato, I.4
Sho, M.5
Nakajima, Y.6
Zhou, J.7
Li, B.Z.8
Shi, Y.H.9
Xiao, Y.S.10
Xu, Y.11
Fan, J.12
-
23
-
-
84878962707
-
PTEN loss increases PD-L1 protein expression and affects the correlation between PD-L1 expression and clinical parameters in colorectal cancer
-
Song M, Chen D, Lu B, Wang C, Zhang J, Huang L, Wang X, Timmons CL, Hu J, Liu B, Wu X, Wang L, Wang J, et al. PTEN loss increases PD-L1 protein expression and affects the correlation between PD-L1 expression and clinical parameters in colorectal cancer. PLoS One. 2013; 8:e65821. doi: 10.1371/journal.pone.0065821.
-
(2013)
PLoS One
, vol.8
-
-
Song, M.1
Chen, D.2
Lu, B.3
Wang, C.4
Zhang, J.5
Huang, L.6
Wang, X.7
Timmons, C.L.8
Hu, J.9
Liu, B.10
Wu, X.11
Wang, L.12
Wang, J.13
-
24
-
-
33745491116
-
Immunohistochemical localization of programmed death-1 ligand-1 (PD-L1) in gastric carcinoma and its clinical significant
-
Wu C, Zhu Y, Jiang J, Zhao J, Zhang XG, Xu N. Immunohistochemical localization of programmed death-1 ligand-1 (PD-L1) in gastric carcinoma and its clinical significant. Acta Histochem. 2006; 108:19-24. doi:10.1016/j.acthis.2006.01.003.
-
(2006)
Acta Histochem
, vol.108
, pp. 19-24
-
-
Wu, C.1
Zhu, Y.2
Jiang, J.3
Zhao, J.4
Zhang, X.G.5
Xu, N.6
-
25
-
-
84905127087
-
Combination of microtubule associated protein-tau and β-tubulin III predicts chemosensitivity of paclitaxel in patients with advanced gastric cancer
-
Yu J, Gao J, Lu Z, Gong J, Li Y, Dong B, Li Z, Zhang X, Shen L. Combination of microtubule associated protein-tau and β-tubulin III predicts chemosensitivity of paclitaxel in patients with advanced gastric cancer. Eur J Cancer. 2014; 50:2328-35. doi: 10.1016/j.ejca.2014.06.017.
-
(2014)
Eur J Cancer
, vol.50
, pp. 2328-2335
-
-
Yu, J.1
Gao, J.2
Lu, Z.3
Gong, J.4
Li, Y.5
Dong, B.6
Li, Z.7
Zhang, X.8
Shen, L.9
-
26
-
-
84920956735
-
Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients
-
Herbst RS, Soria JC, Kowanetz M, Fine GD, Hamid O, Gordon MS. Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients. Nature. 2014; 515:563-7. doi: 10.1038/nature14011.
-
(2014)
Nature
, vol.515
, pp. 563-567
-
-
Herbst, R.S.1
Soria, J.C.2
Kowanetz, M.3
Fine, G.D.4
Hamid, O.5
Gordon, M.S.6
|