CD8+ T cell breadth and ex vivo virus inhibition capacity distinguish between viremic controllers with and without protective HLA class i alleles

Journal of Virology

Volumn 90, Issue 15, 2016, Pages 6818-6831

  Koofhethile, Catherine K ^a   Ndhlovu, Zaza M ^a,b   Thobakgale Tshabalala, Christina ^a   Prado, Julia G ^c   Ismail, Nasreen ^a   Mncube, Zenele ^a   Mkhize, Lungile ^a   van der Stok, Mary ^a   Yende, Nonhlanhla ^d   Walker, Bruce D ^a,b   Goulder, Philip J R ^a,e   Ndung'ua, Thumbi ^a,b,f  

^a UNIVERSITY OF KWAZULU NATAL   (South Africa)

^b HARVARD UNIVERSITY   (United States)

^c HOSPITAL UNIVERSITARI DE BELLVITGE   (Spain)

^d UNIVERSITY OF KWAZULU NATAL   (South Africa)

^e UNIVERSITY OF OXFORD   (United Kingdom)

^f MAX PLANCK INSTITUTE FOR INFECTION BIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; GAG PROTEIN; HLA A1 ANTIGEN; HLA ANTIGEN CLASS 1; HLA B27 ANTIGEN; HLA B57 ANTIGEN;

ADULT; ALLELE; ARTICLE; CD8+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; ENZYME LINKED IMMUNOSPOT ASSAY; EX VIVO STUDY; GENE SEQUENCE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN IMMUNODEFICIENCY VIRUS TYPE 1 SUBTYPE C; IMMUNE RESPONSE; LONGITUDINAL STUDY; LYMPHOCYTE PROLIFERATION; PRIORITY JOURNAL; SOUTH AFRICAN; VIREMIA; VIRUS INHIBITION; VIRUS LOAD; VIRUS REPLICATION; DRUG EFFECTS; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HIV INFECTIONS; IMMUNOLOGY; METABOLISM; VIROLOGY;

ADULT; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; CD8-POSITIVE T-LYMPHOCYTES; HISTOCOMPATIBILITY ANTIGENS CLASS I; HIV INFECTIONS; HIV-1; HUMANS; LONGITUDINAL STUDIES; T-LYMPHOCYTES, CYTOTOXIC; VIRAL LOAD; VIREMIA; VIRUS REPLICATION;

EID: 84982822058     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00276-16     Document Type: Article

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