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Volumn 58, Issue 4, 2017, Pages 866-871

Clinical use of ruxolitinib in an academic medical center in unselected patients with myeloproliferative neoplasms not on clinical study

Author keywords

Myelofibrosis; myeloproliferative neoplasms; ruxolitinib; splenomegaly

Indexed keywords

2 [1 (4 FLUOROPHENYL)ETHYLAMINO] 4 (1 METHYL 1H PYRAZOL 4 YL) 6 (2 PYRAZINYLAMINO)PYRIDINE; ANAGRELIDE; AZACITIDINE; CYTARABINE; DANAZOL; DECITABINE; GANDOTINIB; HEMOGLOBIN; HYDROXYUREA; IMMUNOMODULATING AGENT; MOMELOTINIB; N,N DICYCLOPROPYL 4 [(1,5 DIMETHYL 1H PYRAZOL 3 YL)AMINO] 6 ETHYL 1,6 DIHYDRO 1 METHYLIMIDAZO[4,5 D]PYRROLO[2,3 B]PYRIDINE 7 CARBOXAMIDE; PACRITINIB; RUXOLITINIB; ANTINEOPLASTIC AGENT; JANUS KINASE 2; PROTEIN KINASE INHIBITOR; PYRAZOLE DERIVATIVE;

EID: 84982786659     PISSN: 10428194     EISSN: 10292403     Source Type: Journal    
DOI: 10.1080/10428194.2016.1217528     Document Type: Article
Times cited : (5)

References (24)
  • 1
    • 38349101871 scopus 로고    scopus 로고
    • Classification and diagnosis of myeloproliferative neoplasms: the 2008 World Health Organization criteria and point-of-care diagnostic algorithms
    • Tefferi A, Vardiman JW., Classification and diagnosis of myeloproliferative neoplasms:the 2008 World Health Organization criteria and point-of-care diagnostic algorithms. Leukemia. 2008;22:14–22.
    • (2008) Leukemia , vol.22 , pp. 14-22
    • Tefferi, A.1    Vardiman, J.W.2
  • 2
    • 39149105615 scopus 로고    scopus 로고
    • Proposed criteria for the diagnosis of post-polycythemia vera and post-essential thrombocythemia myelofibrosis: a consensus statement from the International Working Group for Myelofibrosis Research and Treatment
    • Barosi G, Mesa RA, Thiele J, et al. Proposed criteria for the diagnosis of post-polycythemia vera and post-essential thrombocythemia myelofibrosis:a consensus statement from the International Working Group for Myelofibrosis Research and Treatment. Leukemia. 2008;22:437–438.
    • (2008) Leukemia , vol.22 , pp. 437-438
    • Barosi, G.1    Mesa, R.A.2    Thiele, J.3
  • 3
    • 79954433836 scopus 로고    scopus 로고
    • Circulating interleukin (IL)-8, IL-2R, IL-12, and IL-15 levels are independently prognostic in primary myelofibrosis: a comprehensive cytokine profiling study
    • Tefferi A, Vaidya R, Caramazza D, et al. Circulating interleukin (IL)-8, IL-2R, IL-12, and IL-15 levels are independently prognostic in primary myelofibrosis:a comprehensive cytokine profiling study. J Clin Oncol. 2011;29:1356–1363.
    • (2011) J Clin Oncol , vol.29 , pp. 1356-1363
    • Tefferi, A.1    Vaidya, R.2    Caramazza, D.3
  • 4
    • 0032916213 scopus 로고    scopus 로고
    • Population-based incidence and survival figures in essential thrombocythemia and agnogenic myeloid metaplasia: an Olmsted County Study, 1976-1995
    • Mesa RA, Silverstein MN, Jacobsen SJ, et al. Population-based incidence and survival figures in essential thrombocythemia and agnogenic myeloid metaplasia:an Olmsted County Study, 1976-1995. Am J Hematol. 1999;61:10–15.
    • (1999) Am J Hematol , vol.61 , pp. 10-15
    • Mesa, R.A.1    Silverstein, M.N.2    Jacobsen, S.J.3
  • 5
    • 63849328927 scopus 로고    scopus 로고
    • New prognostic scoring system for primary myelofibrosis based on a study of the International Working Group for Myelofibrosis Research and Treatment
    • Cervantes F, Dupriez B, Pereira A, et al. New prognostic scoring system for primary myelofibrosis based on a study of the International Working Group for Myelofibrosis Research and Treatment. Blood. 2009;113:2895–2901.
    • (2009) Blood , vol.113 , pp. 2895-2901
    • Cervantes, F.1    Dupriez, B.2    Pereira, A.3
  • 6
    • 47549083663 scopus 로고    scopus 로고
    • The myelodysplastic/myeloproliferative neoplasms: myeloproliferative diseases with dysplastic features
    • Orazi A, Germing U., The myelodysplastic/myeloproliferative neoplasms:myeloproliferative diseases with dysplastic features. Leukemia. 2008;22:1308–1319.
    • (2008) Leukemia , vol.22 , pp. 1308-1319
    • Orazi, A.1    Germing, U.2
  • 7
    • 17844383458 scopus 로고    scopus 로고
    • A unique clonal JAK2 mutation leading to constitutive signaling causes polycythemia vera
    • James C, Ugo V, Le Couedic JP, et al. A unique clonal JAK2 mutation leading to constitutive signaling causes polycythemia vera. Nature. 2005;434:1144–1148.
    • (2005) Nature , vol.434 , pp. 1144-1148
    • James, C.1    Ugo, V.2    Le Couedic, J.P.3
  • 8
    • 84863393110 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled trial of ruxolitinib for myelofibrosis
    • Verstovsek S, Mesa RA, Gotlib J, et al. A double-blind, placebo-controlled trial of ruxolitinib for myelofibrosis. N Engl J Med. 2012;366:799–807.
    • (2012) N Engl J Med , vol.366 , pp. 799-807
    • Verstovsek, S.1    Mesa, R.A.2    Gotlib, J.3
  • 9
    • 84857837774 scopus 로고    scopus 로고
    • JAK inhibition with ruxolitinib versus best available therapy for myelofibrosis
    • Harrison C, Kiladjian JJ, Al-Ali HK, et al. JAK inhibition with ruxolitinib versus best available therapy for myelofibrosis. N Engl J Med. 2012;366:787–798.
    • (2012) N Engl J Med , vol.366 , pp. 787-798
    • Harrison, C.1    Kiladjian, J.J.2    Al-Ali, H.K.3
  • 10
    • 84887954865 scopus 로고    scopus 로고
    • Ruxolitinib in clinical practice for therapy of myelofibrosis: single USA center experience following Food and Drug Administration approval
    • Geyer H, Cannon K, Knight E, et al. Ruxolitinib in clinical practice for therapy of myelofibrosis:single USA center experience following Food and Drug Administration approval. Leukemia Lymphoma. 2014;55:195–197.
    • (2014) Leukemia Lymphoma , vol.55 , pp. 195-197
    • Geyer, H.1    Cannon, K.2    Knight, E.3
  • 11
    • 85009956258 scopus 로고    scopus 로고
    • Clinical efficacy and safety of ruxolitinib in the management of myelofibrosis: a single institution experience in Taiwan
    • Chen YY, Huang CE, Lee KD, et al. Clinical efficacy and safety of ruxolitinib in the management of myelofibrosis:a single institution experience in Taiwan. Hematology. 2016;21:3–9.
    • (2016) Hematology , vol.21 , pp. 3-9
    • Chen, Y.Y.1    Huang, C.E.2    Lee, K.D.3
  • 12
    • 84955723723 scopus 로고    scopus 로고
    • Ruxolitinib treatment for myelofibrosis: efficacy and tolerability in routine practice
    • Ellis MH, Lavi N, Mishchenko E, et al. Ruxolitinib treatment for myelofibrosis:efficacy and tolerability in routine practice. Leukemia Res. 2015;39:1154–1158.
    • (2015) Leukemia Res , vol.39 , pp. 1154-1158
    • Ellis, M.H.1    Lavi, N.2    Mishchenko, E.3
  • 13
    • 84886769072 scopus 로고    scopus 로고
    • Revised response criteria for myelofibrosis: International Working Group-Myeloproliferative Neoplasms Research and Treatment (IWG-MRT) and European LeukemiaNet (ELN) consensus report
    • Tefferi A, Cervantes F, Mesa R, et al. Revised response criteria for myelofibrosis:International Working Group-Myeloproliferative Neoplasms Research and Treatment (IWG-MRT) and European LeukemiaNet (ELN) consensus report. Blood. 2013;122:1395–1398.
    • (2013) Blood , vol.122 , pp. 1395-1398
    • Tefferi, A.1    Cervantes, F.2    Mesa, R.3
  • 14
    • 77957955039 scopus 로고    scopus 로고
    • Dynamic International Prognostic Scoring System (DIPSS) predicts progression to acute myeloid leukemia in primary myelofibrosis
    • Passamonti F, Cervantes F, Vannucchi AM, et al. Dynamic International Prognostic Scoring System (DIPSS) predicts progression to acute myeloid leukemia in primary myelofibrosis. Blood. 2010;116:2857–2858.
    • (2010) Blood. , vol.116 , pp. 2857-2858
    • Passamonti, F.1    Cervantes, F.2    Vannucchi, A.M.3
  • 15
    • 84908887878 scopus 로고    scopus 로고
    • Development of extramedullary sites of leukemia during ruxolitinib therapy for myelofibrosis
    • Kremyanskaya M, Mascarenhas J, Rampal R, et al. Development of extramedullary sites of leukemia during ruxolitinib therapy for myelofibrosis. Br J Haematol. 2014;167:144–146.
    • (2014) Br J Haematol , vol.167 , pp. 144-146
    • Kremyanskaya, M.1    Mascarenhas, J.2    Rampal, R.3
  • 16
    • 84861216420 scopus 로고    scopus 로고
    • Phase 2 study of the JAK kinase inhibitor ruxolitinib in patients with refractory leukemias, including postmyeloproliferative neoplasm acute myeloid leukemia
    • Eghtedar A, Verstovsek S, Estrov Z, et al. Phase 2 study of the JAK kinase inhibitor ruxolitinib in patients with refractory leukemias, including postmyeloproliferative neoplasm acute myeloid leukemia. Blood. 2012;119:4614–4618.
    • (2012) Blood , vol.119 , pp. 4614-4618
    • Eghtedar, A.1    Verstovsek, S.2    Estrov, Z.3
  • 17
    • 84923611231 scopus 로고    scopus 로고
    • A phase I/II study of the Janus kinase (JAK)1 and 2 inhibitor ruxolitinib in patients with relapsed or refractory acute myeloid leukemia
    • Pemmaraju N, Kantarjian H, Kadia T, et al. A phase I/II study of the Janus kinase (JAK)1 and 2 inhibitor ruxolitinib in patients with relapsed or refractory acute myeloid leukemia. Clin Lymphoma Myeloma Leuk. 2015;15:171–176.
    • (2015) Clin Lymphoma Myeloma Leuk , vol.15 , pp. 171-176
    • Pemmaraju, N.1    Kantarjian, H.2    Kadia, T.3
  • 18
    • 43749117734 scopus 로고    scopus 로고
    • A phase II study of 5-azacitidine for patients with primary and post-essential thrombocythemia/polycythemia vera myelofibrosis
    • Quintás-Cardama A, Tong W, Kantarjian H, et al. A phase II study of 5-azacitidine for patients with primary and post-essential thrombocythemia/polycythemia vera myelofibrosis. Leukemia. 2008;22:965–970.
    • (2008) Leukemia , vol.22 , pp. 965-970
    • Quintás-Cardama, A.1    Tong, W.2    Kantarjian, H.3
  • 19
    • 58249096418 scopus 로고    scopus 로고
    • 5-Azacitidine has limited therapeutic activity in myelofibrosis
    • Mesa RA, Verstovsek S, Rivera C, et al. 5-Azacitidine has limited therapeutic activity in myelofibrosis. Leukemia. 2009;23:180–182.
    • (2009) Leukemia , vol.23 , pp. 180-182
    • Mesa, R.A.1    Verstovsek, S.2    Rivera, C.3
  • 20
    • 78149453788 scopus 로고    scopus 로고
    • Treatment of progression of Philadelphia-negative myeloproliferative neoplasms to myelodysplastic syndrome or acute myeloid leukemia by azacitidine: a report on 54 cases on the behalf of the Groupe Francophone des Myelodysplasies (GFM)
    • Thepot S, Itzykson R, Seegers V, et al. Treatment of progression of Philadelphia-negative myeloproliferative neoplasms to myelodysplastic syndrome or acute myeloid leukemia by azacitidine:a report on 54 cases on the behalf of the Groupe Francophone des Myelodysplasies (GFM). Blood. 2010;116:3735–3742.
    • (2010) Blood , vol.116 , pp. 3735-3742
    • Thepot, S.1    Itzykson, R.2    Seegers, V.3
  • 21
    • 77955276771 scopus 로고    scopus 로고
    • Therapeutic options for patients with myelofibrosis in blast phase
    • Mascarenhas J, Navada S, Malone A, et al. Therapeutic options for patients with myelofibrosis in blast phase. Leukemia Res. 2010;34:1246–1249.
    • (2010) Leukemia Res , vol.34 , pp. 1246-1249
    • Mascarenhas, J.1    Navada, S.2    Malone, A.3
  • 22
    • 84940961594 scopus 로고    scopus 로고
    • Therapeutic benefit of decitabine, a hypomethylating agent, in patients with high-risk primary myelofibrosis and myeloproliferative neoplasm in accelerated or blastic/acute myeloid leukemia phase
    • Badar T, Kantarjian HM, Ravandi F, et al. Therapeutic benefit of decitabine, a hypomethylating agent, in patients with high-risk primary myelofibrosis and myeloproliferative neoplasm in accelerated or blastic/acute myeloid leukemia phase. Leukemia Res. 2015;39:950–956.
    • (2015) Leukemia Res , vol.39 , pp. 950-956
    • Badar, T.1    Kantarjian, H.M.2    Ravandi, F.3
  • 23
    • 84923855168 scopus 로고    scopus 로고
    • Ruxolitinib in combination with DNA methyltransferase inhibitors: clinical responses in patients with symptomatic myelofibrosis with cytopenias and elevated blast(s) counts
    • Tabarroki A, Saunthararajah Y, Visconte V, et al. Ruxolitinib in combination with DNA methyltransferase inhibitors:clinical responses in patients with symptomatic myelofibrosis with cytopenias and elevated blast(s) counts. Leukemia Lymphoma. 2015;56:497–499.
    • (2015) Leukemia Lymphoma , vol.56 , pp. 497-499
    • Tabarroki, A.1    Saunthararajah, Y.2    Visconte, V.3
  • 24
    • 84925226368 scopus 로고    scopus 로고
    • Combination therapy with ruxolitinib plus 5-azacytidine or continuous infusion of low dose cytarabine is feasible in patients with blast-phase myeloproliferative neoplasms
    • Mwirigi A, Galli S, Keohane C, et al. Combination therapy with ruxolitinib plus 5-azacytidine or continuous infusion of low dose cytarabine is feasible in patients with blast-phase myeloproliferative neoplasms. Br J Haematol. 2014;167:714–716.
    • (2014) Br J Haematol , vol.167 , pp. 714-716
    • Mwirigi, A.1    Galli, S.2    Keohane, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.