메뉴 건너뛰기




Volumn 39, Issue 9, 2015, Pages 950-956

Therapeutic benefit of decitabine, a hypomethylating agent, in patients with high-risk primary myelofibrosis and myeloproliferative neoplasm in accelerated or blastic/acute myeloid leukemia phase

Author keywords

Accelerated phase; AML; Decitabine; Myelofibrosis; Myeloproliferative neoplasm

Indexed keywords

ANAGRELIDE; ANTIANEMIC AGENT; CYTARABINE; DECITABINE; GEMTUZUMAB OZOGAMICIN; GRANULOCYTE COLONY STIMULATING FACTOR; HYDROXYUREA; IDARUBICIN; IMATINIB; LENALIDOMIDE; POMALIDOMIDE; PREDNISONE; RUXOLITINIB; THALIDOMIDE; ANTINEOPLASTIC ANTIMETABOLITE; AZACITIDINE;

EID: 84940961594     PISSN: 01452126     EISSN: 18735835     Source Type: Journal    
DOI: 10.1016/j.leukres.2015.06.001     Document Type: Article
Times cited : (69)

References (38)
  • 1
    • 84872970465 scopus 로고    scopus 로고
    • Primary myelofibrosis: 2013 update on diagnosis, risk-stratification, and management
    • Tefferi A. Primary myelofibrosis: 2013 update on diagnosis, risk-stratification, and management. Am. J. Hematol. 2013, 88(2):141-150.
    • (2013) Am. J. Hematol. , vol.88 , Issue.2 , pp. 141-150
    • Tefferi, A.1
  • 2
    • 12844284481 scopus 로고    scopus 로고
    • Leukemic transformation in myelofibrosis with myeloid metaplasia: a single-institution experience with 91 cases
    • Mesa R.A., et al. Leukemic transformation in myelofibrosis with myeloid metaplasia: a single-institution experience with 91 cases. Blood 2005, 105(3):973-977.
    • (2005) Blood , vol.105 , Issue.3 , pp. 973-977
    • Mesa, R.A.1
  • 3
    • 79952087335 scopus 로고    scopus 로고
    • DIPSS plus: a refined Dynamic International Prognostic Scoring System for primary myelofibrosis that incorporates prognostic information from karyotype, platelet count, and transfusion status
    • Gangat N., et al. DIPSS plus: a refined Dynamic International Prognostic Scoring System for primary myelofibrosis that incorporates prognostic information from karyotype, platelet count, and transfusion status. J. Clin. Oncol. 2011, 29(4):392-397.
    • (2011) J. Clin. Oncol. , vol.29 , Issue.4 , pp. 392-397
    • Gangat, N.1
  • 4
    • 71949121402 scopus 로고    scopus 로고
    • Pomalidomide is active in the treatment of anemia associated with myelofibrosis
    • Tefferi A., et al. Pomalidomide is active in the treatment of anemia associated with myelofibrosis. J. Clin. Oncol. 2009, 27(27):4563-4569.
    • (2009) J. Clin. Oncol. , vol.27 , Issue.27 , pp. 4563-4569
    • Tefferi, A.1
  • 5
    • 33747167338 scopus 로고    scopus 로고
    • Lenalidomide therapy in myelofibrosis with myeloid metaplasia
    • Tefferi A., et al. Lenalidomide therapy in myelofibrosis with myeloid metaplasia. Blood 2006, 108(4):1158-1164.
    • (2006) Blood , vol.108 , Issue.4 , pp. 1158-1164
    • Tefferi, A.1
  • 6
    • 49449108604 scopus 로고    scopus 로고
    • Bortezomib therapy in myelofibrosis: a phase II clinical trial
    • Mesa R.A., et al. Bortezomib therapy in myelofibrosis: a phase II clinical trial. Leukemia 2008, 22(8):1636-1638.
    • (2008) Leukemia , vol.22 , Issue.8 , pp. 1636-1638
    • Mesa, R.A.1
  • 7
    • 34548136103 scopus 로고    scopus 로고
    • A phase II trial of tipifarnib in myelofibrosis: primary, post-polycythemia vera and post-essential thrombocythemia
    • Mesa R.A., et al. A phase II trial of tipifarnib in myelofibrosis: primary, post-polycythemia vera and post-essential thrombocythemia. Leukemia 2007, 21(9):1964-1970.
    • (2007) Leukemia , vol.21 , Issue.9 , pp. 1964-1970
    • Mesa, R.A.1
  • 8
    • 33746989740 scopus 로고    scopus 로고
    • Thalidomide versus placebo in myeloid metaplasia with myelofibrosis: a prospective, randomized, double-blind, multicenter study
    • Abgrall J.F., et al. Thalidomide versus placebo in myeloid metaplasia with myelofibrosis: a prospective, randomized, double-blind, multicenter study. Haematologica 2006, 91(8):1027-1032.
    • (2006) Haematologica , vol.91 , Issue.8 , pp. 1027-1032
    • Abgrall, J.F.1
  • 9
    • 84857837774 scopus 로고    scopus 로고
    • JAK inhibition with ruxolitinib versus best available therapy for myelofibrosis
    • Harrison C., et al. JAK inhibition with ruxolitinib versus best available therapy for myelofibrosis. N. Engl. J. Med. 2012, 366(9):787-798.
    • (2012) N. Engl. J. Med. , vol.366 , Issue.9 , pp. 787-798
    • Harrison, C.1
  • 10
    • 84863393110 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled trial of ruxolitinib for myelofibrosis
    • Verstovsek S., et al. A double-blind, placebo-controlled trial of ruxolitinib for myelofibrosis. N. Engl. J. Med. 2012, 366(9):799-807.
    • (2012) N. Engl. J. Med. , vol.366 , Issue.9 , pp. 799-807
    • Verstovsek, S.1
  • 11
    • 84924784207 scopus 로고    scopus 로고
    • Three-year efficacy, overall survival, and safety of ruxolitinib therapy in patients with myelofibrosis from the COMFORT-I study
    • Verstovsek S., et al. Three-year efficacy, overall survival, and safety of ruxolitinib therapy in patients with myelofibrosis from the COMFORT-I study. Haematologica 2015, 100(4):478-488.
    • (2015) Haematologica , vol.100 , Issue.4 , pp. 478-488
    • Verstovsek, S.1
  • 12
    • 39749167036 scopus 로고    scopus 로고
    • New and old treatment modalities in primary myelofibrosis
    • Cervantes F., Mesa R., Barosi G. New and old treatment modalities in primary myelofibrosis. Cancer J. 2007, 13(6):377-383.
    • (2007) Cancer J. , vol.13 , Issue.6 , pp. 377-383
    • Cervantes, F.1    Mesa, R.2    Barosi, G.3
  • 13
    • 0037309554 scopus 로고    scopus 로고
    • Polycythemia vera in young patients: a study on the long-term risk of thrombosis, myelofibrosis and leukemia
    • Passamonti F., et al. Polycythemia vera in young patients: a study on the long-term risk of thrombosis, myelofibrosis and leukemia. Haematologica 2003, 88(1):13-18.
    • (2003) Haematologica , vol.88 , Issue.1 , pp. 13-18
    • Passamonti, F.1
  • 14
    • 52649131772 scopus 로고    scopus 로고
    • The natural history and treatment outcome of blast phase BCR-ABL- myeloproliferative neoplasms
    • Tam C.S., et al. The natural history and treatment outcome of blast phase BCR-ABL- myeloproliferative neoplasms. Blood 2008, 112(5):1628-1637.
    • (2008) Blood , vol.112 , Issue.5 , pp. 1628-1637
    • Tam, C.S.1
  • 15
    • 23844483519 scopus 로고    scopus 로고
    • Leukemic transformation of polycythemia vera: a single center study of 23 patients
    • Passamonti F., et al. Leukemic transformation of polycythemia vera: a single center study of 23 patients. Cancer 2005, 104(5):1032-1036.
    • (2005) Cancer , vol.104 , Issue.5 , pp. 1032-1036
    • Passamonti, F.1
  • 16
    • 84883742034 scopus 로고    scopus 로고
    • Mutations and prognosis in primary myelofibrosis
    • Vannucchi A.M., et al. Mutations and prognosis in primary myelofibrosis. Leukemia 2013, 27(9):1861-1869.
    • (2013) Leukemia , vol.27 , Issue.9 , pp. 1861-1869
    • Vannucchi, A.M.1
  • 17
    • 0036008494 scopus 로고    scopus 로고
    • Hypermethylation of the P15INK4b and P16INK4a in agnogenic myeloid metaplasia (AMM) and AMM in leukaemic transformation
    • Wang J.C., et al. Hypermethylation of the P15INK4b and P16INK4a in agnogenic myeloid metaplasia (AMM) and AMM in leukaemic transformation. Br. J. Haematol. 2002, 116(3):582-586.
    • (2002) Br. J. Haematol. , vol.116 , Issue.3 , pp. 582-586
    • Wang, J.C.1
  • 18
    • 0141956031 scopus 로고    scopus 로고
    • Critical review of pathogenetic mechanisms in myelofibrosis with myeloid metaplasia
    • Martyre M.C. Critical review of pathogenetic mechanisms in myelofibrosis with myeloid metaplasia. Curr. Hematol. Rep. 2003, 2(3):257-263.
    • (2003) Curr. Hematol. Rep. , vol.2 , Issue.3 , pp. 257-263
    • Martyre, M.C.1
  • 19
    • 0035760303 scopus 로고    scopus 로고
    • + cells in myelofibrosis with myeloid metaplasia
    • + cells in myelofibrosis with myeloid metaplasia. Blood 2001, 98(12):3249-3255.
    • (2001) Blood , vol.98 , Issue.12 , pp. 3249-3255
    • Barosi, G.1
  • 20
    • 70350233460 scopus 로고    scopus 로고
    • + cells by treatment with chromatin-modifying agents
    • + cells by treatment with chromatin-modifying agents. Cancer Res. 2009, 69(19):7612-7618.
    • (2009) Cancer Res. , vol.69 , Issue.19 , pp. 7612-7618
    • Wang, X.1
  • 21
    • 34447118173 scopus 로고    scopus 로고
    • + cells from patients with idiopathic myelofibrosis
    • + cells from patients with idiopathic myelofibrosis. Cancer Res. 2007, 67(13):6417-6424.
    • (2007) Cancer Res. , vol.67 , Issue.13 , pp. 6417-6424
    • Shi, J.1
  • 22
    • 84873454471 scopus 로고    scopus 로고
    • Methylome profiling reveals distinct alterations in phenotypic and mutational subgroups of myeloproliferative neoplasms
    • Nischal S., et al. Methylome profiling reveals distinct alterations in phenotypic and mutational subgroups of myeloproliferative neoplasms. Cancer Res. 2013, 73(3):1076-1085.
    • (2013) Cancer Res. , vol.73 , Issue.3 , pp. 1076-1085
    • Nischal, S.1
  • 23
    • 34547989446 scopus 로고    scopus 로고
    • Decitabine and its role in the treatment of hematopoietic malignancies
    • Plimack E.R., Kantarjian H.M., Issa J.P. Decitabine and its role in the treatment of hematopoietic malignancies. Leuk. Lymphoma 2007, 48(8):1472-1481.
    • (2007) Leuk. Lymphoma , vol.48 , Issue.8 , pp. 1472-1481
    • Plimack, E.R.1    Kantarjian, H.M.2    Issa, J.P.3
  • 24
    • 67449147110 scopus 로고    scopus 로고
    • Targeting DNA methylation
    • Issa J.P., Kantarjian H.M. Targeting DNA methylation. Clin. Cancer Res. 2009, 15(12):3938-3946.
    • (2009) Clin. Cancer Res. , vol.15 , Issue.12 , pp. 3938-3946
    • Issa, J.P.1    Kantarjian, H.M.2
  • 25
    • 33846011361 scopus 로고    scopus 로고
    • Results of a randomized study of 3 schedules of low-dose decitabine in higher-risk myelodysplastic syndrome and chronic myelomonocytic leukemia
    • Kantarjian H., et al. Results of a randomized study of 3 schedules of low-dose decitabine in higher-risk myelodysplastic syndrome and chronic myelomonocytic leukemia. Blood 2007, 109(1):52-57.
    • (2007) Blood , vol.109 , Issue.1 , pp. 52-57
    • Kantarjian, H.1
  • 26
    • 0037093195 scopus 로고    scopus 로고
    • Randomized controlled trial of azacitidine in patients with the myelodysplastic syndrome: a study of the cancer and leukemia group B
    • Silverman L.R., et al. Randomized controlled trial of azacitidine in patients with the myelodysplastic syndrome: a study of the cancer and leukemia group B. J. Clin. Oncol. 2002, 20(10):2429-2440.
    • (2002) J. Clin. Oncol. , vol.20 , Issue.10 , pp. 2429-2440
    • Silverman, L.R.1
  • 27
    • 77955276771 scopus 로고    scopus 로고
    • Therapeutic options for patients with myelofibrosis in blast phase
    • Mascarenhas J., et al. Therapeutic options for patients with myelofibrosis in blast phase. Leuk. Res. 2010, 34(9):1246-1249.
    • (2010) Leuk. Res. , vol.34 , Issue.9 , pp. 1246-1249
    • Mascarenhas, J.1
  • 28
    • 78149453788 scopus 로고    scopus 로고
    • Treatment of progression of Philadelphia-negative myeloproliferative neoplasms to myelodysplastic syndrome or acute myeloid leukemia by azacitidine: a report on 54 cases on the behalf of the Groupe Francophone des Myelodysplasies (GFM)
    • Thepot S., et al. Treatment of progression of Philadelphia-negative myeloproliferative neoplasms to myelodysplastic syndrome or acute myeloid leukemia by azacitidine: a report on 54 cases on the behalf of the Groupe Francophone des Myelodysplasies (GFM). Blood 2010, 116(19):3735-3742.
    • (2010) Blood , vol.116 , Issue.19 , pp. 3735-3742
    • Thepot, S.1
  • 29
    • 43749117734 scopus 로고    scopus 로고
    • A phase II study of 5-azacitidine for patients with primary and post-essential thrombocythemia/polycythemia vera myelofibrosis
    • Quintas-Cardama A., et al. A phase II study of 5-azacitidine for patients with primary and post-essential thrombocythemia/polycythemia vera myelofibrosis. Leukemia 2008, 22(5):965-970.
    • (2008) Leukemia , vol.22 , Issue.5 , pp. 965-970
    • Quintas-Cardama, A.1
  • 30
    • 70349256226 scopus 로고    scopus 로고
    • The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes
    • Vardiman J.W., et al. The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes. Blood 2009, 114(5):937-951.
    • (2009) Blood , vol.114 , Issue.5 , pp. 937-951
    • Vardiman, J.W.1
  • 31
    • 84868206008 scopus 로고    scopus 로고
    • Proposed criteria for response assessment in patients treated in clinical trials for myeloproliferative neoplasms in blast phase (MPN-BP): formal recommendations from the post-myeloproliferative neoplasm acute myeloid leukemia consortium
    • Mascarenhas J., et al. Proposed criteria for response assessment in patients treated in clinical trials for myeloproliferative neoplasms in blast phase (MPN-BP): formal recommendations from the post-myeloproliferative neoplasm acute myeloid leukemia consortium. Leuk. Res. 2012, 36(12):1500-1504.
    • (2012) Leuk. Res. , vol.36 , Issue.12 , pp. 1500-1504
    • Mascarenhas, J.1
  • 32
    • 84886769072 scopus 로고    scopus 로고
    • Revised response criteria for myelofibrosis: International Working Group-Myeloproliferative Neoplasms Research and Treatment (IWG-MRT) and European LeukemiaNet (ELN) consensus report
    • Tefferi A., et al. Revised response criteria for myelofibrosis: International Working Group-Myeloproliferative Neoplasms Research and Treatment (IWG-MRT) and European LeukemiaNet (ELN) consensus report. Blood 2013, 122(8):1395-1398.
    • (2013) Blood , vol.122 , Issue.8 , pp. 1395-1398
    • Tefferi, A.1
  • 33
    • 33745968917 scopus 로고    scopus 로고
    • Clinical application and proposal for modification of the International Working Group (IWG) response criteria in myelodysplasia
    • Cheson B.D., et al. Clinical application and proposal for modification of the International Working Group (IWG) response criteria in myelodysplasia. Blood 2006, 108(2):419-425.
    • (2006) Blood , vol.108 , Issue.2 , pp. 419-425
    • Cheson, B.D.1
  • 34
    • 84887014885 scopus 로고    scopus 로고
    • Efficacy, safety and survival with ruxolitinib in patients with myelofibrosis: results of a median 2-year follow-up of COMFORT-I
    • Verstovsek S., et al. Efficacy, safety and survival with ruxolitinib in patients with myelofibrosis: results of a median 2-year follow-up of COMFORT-I. Haematologica 2013, 98(12):1865-1871.
    • (2013) Haematologica , vol.98 , Issue.12 , pp. 1865-1871
    • Verstovsek, S.1
  • 35
    • 84861216420 scopus 로고    scopus 로고
    • Phase 2 study of the JAK kinase inhibitor ruxolitinib in patients with refractory leukemias, including postmyeloproliferative neoplasm acute myeloid leukemia
    • Eghtedar A., et al. Phase 2 study of the JAK kinase inhibitor ruxolitinib in patients with refractory leukemias, including postmyeloproliferative neoplasm acute myeloid leukemia. Blood 2012, 119(20):4614-4618.
    • (2012) Blood , vol.119 , Issue.20 , pp. 4614-4618
    • Eghtedar, A.1
  • 36
    • 84928929600 scopus 로고    scopus 로고
    • Ruxolitinib in combination with DNA methyltransferase inhibitors: clinical responses in patients with symptomatic myelofibrosis with cytopenias and elevated blast(s) counts
    • Tabarroki A., et al. Ruxolitinib in combination with DNA methyltransferase inhibitors: clinical responses in patients with symptomatic myelofibrosis with cytopenias and elevated blast(s) counts. Leuk. Lymphoma 2014, 1-3.
    • (2014) Leuk. Lymphoma , pp. 1-3
    • Tabarroki, A.1
  • 37
    • 84875032119 scopus 로고    scopus 로고
    • A phase I study of panobinostat (LBH589) in patients with primary myelofibrosis (PMF) and post-polycythaemia vera/essential thrombocythaemia myelofibrosis (post-PV/ET MF)
    • Mascarenhas J., et al. A phase I study of panobinostat (LBH589) in patients with primary myelofibrosis (PMF) and post-polycythaemia vera/essential thrombocythaemia myelofibrosis (post-PV/ET MF). Br. J. Haematol. 2013, 161(1):68-75.
    • (2013) Br. J. Haematol. , vol.161 , Issue.1 , pp. 68-75
    • Mascarenhas, J.1
  • 38
    • 75749125700 scopus 로고    scopus 로고
    • Outcome of transplantation for myelofibrosis
    • Ballen K.K., et al. Outcome of transplantation for myelofibrosis. Biol. Blood Marrow Transplant. 2010, 16(3):358-367.
    • (2010) Biol. Blood Marrow Transplant. , vol.16 , Issue.3 , pp. 358-367
    • Ballen, K.K.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.