Skeletal muscle dysfunction in the db/db mouse model of type 2 diabetes

Muscle and Nerve

Volumn 54, Issue 3, 2016, Pages 460-468

  Bayley, Jeppe Seamus ^a   Pedersen, Thomas Holm ^a   Nielsen, Ole Bækgaard ^a  

^a AARHUS UNIVERSITY   (Denmark)

Author keywords

excitability; half relaxation time; neuropathy; SERCA; skeletal muscle; type 2 diabetes mellitus

Indexed keywords

SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; TUBOCURARINE CHLORIDE;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ELECTROSTIMULATION; MOTONEURON; MOTOR DYSFUNCTION; MOUSE; MUSCLE ATROPHY; MUSCLE CELL; MUSCLE STRENGTH; MUSCLE TWITCH; NERVE EXCITABILITY; NEUROMUSCULAR JUNCTION; NEUROMUSCULAR TRANSMISSION; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 84982104705     PISSN: 0148639X     EISSN: 10974598     Source Type: Journal    
DOI: 10.1002/mus.25064     Document Type: Article

References (37)

1. Shaw JE, Sicree RA, Zimmet PZ. Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Res Clin Pract 2010;87:4–14.
2. Pirart J. Diabetes Mellitus and its degenerative complications: a prospective study of 4400 patients observed between 1947 and 1973. Diabetes Care 1978;1:252–263.
3. Huang BK, Monu JUV, Doumanian J. Diabetic myopathy: MRI patterns and current trends. AJR Am J Roentgenol 2010;195:198–204.
4. Beghi E, Monticelli ML, Amoruso L, Apollo F, Delodovici ML, Grampa G, et al. Chronic symmetric symptomatic polyneuropathy in the elderly: a field screening investigation in two Italian regions. I. Prevalence and general characteristics of the sample. Neurology 1995;45:1832–1836.
5. Johannsen L, Smith T, Havsager A-M, Madsen C, Kjeldsen MJ, Dalsgaard NJ, et al. Evaluation of patients with symptoms suggestive of chronic polyneuropathy. J Clin Neuromuscul Disord 2001;3:47–52.
6. Andersen H. Motor dysfunction in diabetes. Diabetes Metab Res Rev 2012;28:89–92.
7. Allen MD, Major B, Kimpinski K, Doherty TJ, Rice CL. Skeletal muscle morphology and contractile function in relation to muscle denervation in diabetic neuropathy. J Appl Physiol 2014;116:545–552.
8. Safwat Y, Yassin N, Gamal El Din M, Kassem L. Modulation of skeletal muscle performance and SERCA by exercise and adiponectin gene therapy in insulin-resistant rat. DNA Cell Biol 2013;32:378–385.
9. Davidson LE, Kelley DE, Heshka S, Thornton J, Pi-Sunyer FX, Boxt L, et al. Skeletal muscle and organ masses differ in overweight adults with type 2 diabetes. J Appl Physiol 2014;117:377–382.
10. Allen MD, Kimpinski K, Doherty TJ, Rice CL. Decreased muscle endurance associated with diabetic neuropathy may be attributed partially to neuromuscular transmission failure. J Appl Physiol 2015;118:1014–1022.
11. Quasthoff S. The role of axonal ion conductances in diabetic neuropathy: a review. Muscle Nerve 1998;21:1246–1255.
12. Eshima H, Poole DC, Kano Y. In vivo calcium regulation in diabetic skeletal muscle. Cell Calcium 2014;56:381–389.
13. 2+-ATPase declines independently of slow myosin in soleus muscle of diabetic rats. Acta Biochim Pol 2009;56:487–493.
14. Ganguly PK, Mathur S, Gupta MP, Beamish RE, Dhalla NS. Calcium pump activity of sarcoplasmic reticulum in diabetic rat skeletal muscle. Am J Physiol 1986;251:E515–E523.
15. 2+ transport activity in skeletal muscle of diabetic rats. Am J Physiol 1991;260:E626–E632.
16. Coleman DL, Hummel KP. Studies with the mutation, diabetes, in the mouse. Diabetologia 1967;3:238–248.
17. Broch-Lips M, Pedersen TH, Riisager A, Schmitt-John T, Nielsen OB. Neuro-muscular function in the wobbler murine model of primary motor neuronopathy. Exp Neurol 2013;248:406–415.
18. Martonosi A, Donley JR, Pucell AG, Halpin RA. Sarcoplasmic XI. The mode of involvement reticulum in the hydrolysis of ATP by of phospholipids sarcoplasmic reticulum membranes. Arch Biochem Biophys 1971;144:529–540.
19. 2+-ATPase from sarcoplasmic reticulum in muscle biopsies. Biochem J 1989;260:443–448.
20. Hummel KP, Dickie MM, Coleman DL. Diabetes, a new mutation in the mouse. Science 1966;153:1127–1128.
21. Allen MD, Kimpinski K, Doherty TJ, Rice CL. Length dependent loss of motor axons and altered motor unit properties in human diabetic polyneuropathy. Clin Neurophysiol 2014;125:836–843.
22. Kimura I, Okazaki M, Kimura M. Streptozocin-diabetes phrenic nerve terminal modifies and acetylcholine release from mouse presynaptic to succinylcholine. Jpn J Pharmacol 1993;62:35–41.
23. Fahim MA, Hasan MY, Alshuaib WB. Early morphological remodeling of neuromuscular junction in a murine model of diabetes. J Appl Physiol 2014;89:2235–2240.
24. Kimura M, Kimura I, Nojima H, Muroi M. Diabetes mellitus-induced hypersensitivity of mouse skeletal muscles to acetylcholine and succinylcholine. Jpn J Pharmacol 1986;40:251–256.
25. Garcia CC, Potian JG, Hognason K, Thyagarajan B, Sultatos LG, Souayah N, et al. Acetylcholinesterase deficiency contributes to neuromuscular junction dysfunction in type 1 diabetic neuropathy. Am J Physiol Endocrinol Metab 2012;303:E551–E561.
26. Paton WDM, Waud DR. The margin of safety of neuromuscular transmission. J Physiol 1967;191:59–90.
27. Gollnick PD, Körge P, Karpakka J, Saltin B. Elongation of skeletal muscle relaxation during exercise is linked to reduced calcium uptake by the sarcoplasmic reticulum in man. Acta Physiol Scand 1991;142:135–136.
28. 2+ Sensitivity of skinned cardiac muscle contractility coincident with troponin T band shifts in the diabetic rat. Circ Res 1995;76:600–606.
29. 2+ in genetically obese (ob/ob) mouse single skeletal muscle fibres. Pflugers Arch Eur J Physiol 2002;444:692–699.
30. Marin P, Andersson B, Krotkiewski M, Bjorntorp P. Muscle fibre composition and capillary density in women and men with NIDDM. Diabetes Care 1994;17:382–386.
31. Simoneau JA, Kelley DE. Altered glycolytic and oxidative capacities of skeletal muscle contribute to insulin resistance in NIDDM. J Appl Physiol 1997;83:166–171.
32. Buchthal F, Schmalbruch H. Contraction times and fibre types in intact human muscle. Acta Physiol Scand 1970;79:435–452.
33. Schiaffino S, Reggiani C. Fiber types in mammalian skeletal muscles. Physiol Rev 2011;91:1447–1531.
34. Bowman WC, Goldberg AAJ, Raper C. A comparison between the effects of a tetanus and the effects of sympathomimetic amines on fast- and slow-contracting mammalian muscles. Br J Pharmacol Chemother 1962;19:464–484.
35. Bottinelli R. Functional heterogeneity of mammalian single muscle fibres: do myosin isoforms tell the whole story? Pflugers Arch Eur J Physiol 2001;443:6–17.
36. 2+ sequestration in diabetic mouse islets of Langerhans. J Biol Chem 1994;269:18279–18282.
37. Kono T, Ahn G, Moss DR, Gann L, Zarain-Herzberg A, Nishiki Y, et al. PPAR-γ activation restores pancreatic islet SERCA2 levels and prevents β-cell dysfunction under conditions of hyperglycemic and cytokine stress. Mol Endocrinol 2012;26:257–271.