Cardiovascular benefits from ancient grain bread consumption: findings from a double-blinded randomized crossover intervention trial

International Journal of Food Sciences and Nutrition

Volumn 68, Issue 1, 2017, Pages 97-103

  Sereni, Alice ^a,b   Cesari, Francesca ^a,b   Gori, Anna Maria ^a,b   Maggini, Niccolò ^a,b   Marcucci, Rossella ^a,b   Casini, Alessandro ^b,d   Sofi, Francesco ^b,c,d  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITY OF FLORENCE   (Italy)

^c CAREGGI UNIVERSITY HOSPITAL   (Italy)

^d IRCCS FONDAZIONE DON CARLO GNOCCHI   (Italy)

Author keywords

ancient variety; cardiovascular disease; food; Gran

Indexed keywords

BIOLOGICAL MARKER;

ADULT; AGED; BLOOD; BREAD; CARDIOVASCULAR DISEASES; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED STUDY; CROSSOVER PROCEDURE; DOUBLE BLIND PROCEDURE; ENDOTHELIAL PROGENITOR CELL; FEMALE; FOOD INDUSTRY; FUNCTIONAL FOOD; HUMAN; HYPERCHOLESTEROLEMIA; HYPERGLYCEMIA; ITALY; MALE; MANPOWER; METABOLISM; MIDDLE AGED; MULTICENTER STUDY; ORGANIC FOOD; PATHOPHYSIOLOGY; RANDOMIZED CONTROLLED TRIAL; RISK FACTOR; SPECIES DIFFERENCE; WHOLE GRAIN;

ADULT; AGED; BIOMARKERS; BREAD; CARDIOVASCULAR DISEASES; CROSS-OVER STUDIES; DOUBLE-BLIND METHOD; ENDOTHELIAL PROGENITOR CELLS; FEMALE; FOOD, ORGANIC; FOOD-PROCESSING INDUSTRY; FUNCTIONAL FOOD; HUMANS; HYPERCHOLESTEROLEMIA; HYPERGLYCEMIA; ITALY; MALE; MIDDLE AGED; RISK FACTORS; SPECIES SPECIFICITY; WHOLE GRAINS;

EID: 84981215634     PISSN: 09637486     EISSN: 14653478     Source Type: Journal    
DOI: 10.1080/09637486.2016.1216528     Document Type: Article

References (16)

1. Adom KK, Sorrells ME, Liu RH., 2003. Phytochemical profiles and antioxidant activity of wheat varieties. J Agric Food Chem. 51:7825–7834.
2. Cesari F, Marcucci R, Gori AM, Burgisser C, Francini S, Sofi F, Gensini GF, Abbate R, Fattirolli F. 2013. Impact of a cardiac rehabilitation program and inflammatory state on endothelial progenitor cells in acute coronary syndrome patients. Int J Cardiol. 167:1854–1859.
3. Dangour AD, Lock K, Hayter A, Aikenhead A, Allen E, Uauy R., 2010. Nutrition-related health effects of organic foods:a systematic review. Am J Clin Nutr. 92:203–210.
4. Di Silvestro R, Marotti I, Bosi S, Bregola V, Segura Carretero A, Sedej I, Mandic A, Sakac M, Benedettelli S, Dinelli G. 2012. Health-promoting phytochemicals of Italian common wheat varieties grown under low-input agricultural management. J Sci Food Agric. 92:2800–2810.
5. Dinelli G, Marotti I, Bosi S, Benedettelli S, Ghiselli L, Cortacero-Ramirez S, Carrasco-Pancorbo A, Segura-Carretero A, Fernandez-Gutierrez A. 2007. Lignan profile in seeds of modern and old Italian soft wheat (Triticum aestivum L.) cultivars as revealed by CE-MS analyses. Electrophoresis. 28:4212–4219.
6. Gil A, Ortega RM, Maldonado J., 2011. Wholegrain cereals and bread:a duet of the Mediterranean diet for the prevention of chronic diseases. Public Health Nutr. 14:2316–2322.
7. Magkos F, Arvaniti F, Zampelas A., 2003. Organic food:nutritious food or food for thought? A review of the evidence. Int J Food Sci Nutr. 54:357–371.
8. Mellen PB, Walsh TF, Herrington DM., 2008. Whole grain intake and cardiovascular disease:a meta-analysis. Nutr Metab Cardiovasc Dis. 18:283–290.
9. Smith-Spangler C, Brandeau ML, Hunter GE, Bavinger JC, Pearson M, Eschbach PJ, Sundaram V, Liu H, Schirmer P, Stave C, et al. 2012. Are organic foods safer or healthier than conventional alternatives?:a systematic review. Ann Intern Med. 157:348–366.
10. Sofi F, Ghiselli L, Cesari F, Gori AM, Mannini L, Casini A, Vazzana C, Vecchio V, Gensini GF, Abbate R, Benedettelli S. 2010. Effects of short-term consumption of bread obtained by an old Italian grain variety on lipid, inflammatory, and hemorheological variables:an intervention study. J Med Food. 13:1–6.
11. Sofi F, Whittaker A, Cesari F, Gori AM, Fiorillo C, Becatti M, Marotti I, Dinelli G, Casini A, Abbate R, et al. 2013. Characterization of Khorasan wheat (Kamut) and impact of a replacement diet on cardiovascular risk factors:cross-over dietary intervention study. Eur J Clin Nutr. 67:190–195.
12. Sofi F, Whittaker A, Gori AM, Cesari F, Surrenti E, Abbate R, Gensini GF, Benedettelli S, Casini A. 2014. Effect of Triticum turgidum subsp. Turanicum wheat on irritable bowel syndrome:a double-blinded randomized dietary intervention trial. Br J Nutr. 13:1–8.
13. Truswell AS., 2002. Cereal grains and coronary heart disease. Eur J Clin Nutr. 56:1–14.
14. Van Craenenbroeck EM, Conraads VM., 2010. Endothelial progenitor cells in vascular health:focus on lifestyle. Microvasc Res. 79:184–192.
15. Vrček IV, Čepo DV, Rašić D, Peraica M, Zuntar I, Bojic M, Mendas G, Medic-Saric M., 2013. A comparison of the nutritional value and food safety of organically and conventionally produced wheat flours. Food Chem. 143:522–529.
16. Worthington V., 2001. Nutritional quality of organic versus conventional fruits, vegetables, and grains. J Altern Complement Med. 7:161–173.