Gray matter maturation and cognition in children with different APOE ϵ genotypes

Neurology

Volumn 87, Issue 6, 2016, Pages 585-594

  Chang, Linda ^a   Douet, Vanessa ^a   Bloss, Cinnamon ^b   Lee, Kristin ^a   Pritchett, Alexandra ^a   Jernigan, Terry L ^c   Akshoomoff, Natacha ^c   Murray, Sarah S ^d   Frazier, Jean ^e   Kennedy, David N ^e   Amaral, David G ^f   Gruen, Jeffrey ^g   Kaufmann, Walter E ^h   Casey, B J ⁱ   Sowell, Elizabeth ^j,k   Ernst, Thomas ^a  

^a UNIVERSITY OF HAWAII   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

^g YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^h BOSTON CHILDREN S HOSPITAL   (United States)

ⁱ WEILL CORNELL MEDICAL COLLEGE   (United States)

^j UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^k CHILDREN S HOSPITAL LOS ANGELES   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN E2; APOLIPOPROTEIN E4;

ADOLESCENT; ADULT; AMYGDALA; ARTICLE; ATTENTION; BRAIN CORTEX; BRAIN MATURATION; BRAIN SIZE; CHILD; CHILD DEVELOPMENT; CHILDHOOD DISEASE; COGNITION; CROSS-SECTIONAL STUDY; DIFFUSION TENSOR IMAGING; ENTORHINAL CORTEX; EXECUTIVE FUNCTION; FEMALE; FRACTIONAL ANISOTROPY; GENETIC VARIABILITY; GENOTYPE; GRAY MATTER; HIPPOCAMPUS; HUMAN; MALE; MORPHOMETRICS; MULTICENTER STUDY; NEUROLOGIC DISEASE; NORMAL HUMAN; ORBITAL CORTEX; OUTCOME ASSESSMENT; PARIETAL GYRUS; PRIORITY JOURNAL; SUBCORTEX; THALAMUS; WORKING MEMORY; AGING; ANISOTROPY; BRAIN; GENETICS; NEUROPSYCHOLOGICAL TEST; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; PRESCHOOL CHILD; YOUNG ADULT;

ADOLESCENT; AGING; ANISOTROPY; APOLIPOPROTEIN E4; BRAIN; CHILD; CHILD, PRESCHOOL; COGNITION; CROSS-SECTIONAL STUDIES; FEMALE; GENOTYPE; GRAY MATTER; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; NEUROPSYCHOLOGICAL TESTS; YOUNG ADULT;

EID: 84981194386     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/WNL.0000000000002939     Document Type: Article

References (40)

1. Teasdale GM, Nicoll JA, Murray G, Fiddes M. Association of apolipoprotein E polymorphism with outcome after head injury. Lancet 1997; 350: 1069-1071
2. Kokubo Y, Chowdhury AH, Date C, Yokoyama T, Sobue H, Tanaka H. Age-dependent association of apolipoprotein E genotypes with stroke subtypes in a Japanese rural population. Stroke 2000; 31: 1299-1306
3. Chang L, Andres M, Sadino J, et al. Impact of apolipoprotein E epsilon4 and HIV on cognition and brain atrophy: antagonistic pleiotropy and premature brain aging. Neuroimage 2011; 58: 1017-1027
4. Liu CC, Kanekiyo T, Xu H, Bu G. Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy. Nat Rev Neurol 2013; 9: 106-118
5. Shaw P, Lerch JP, Pruessner JC, et al. Cortical morphology in children and adolescents with different apolipoprotein E gene polymorphisms: an observational study. Lancet Neurol 2007; 6: 494-500
6. Dean DC III, Jerskey BA, Chen K, et al. Brain differences in infants at differential genetic risk for late-onset Alzheimer disease: a cross-sectional imaging study. JAMA Neurol 2014; 71: 11-22
7. Knickmeyer RC, Wang J, Zhu H, et al. Common variants in psychiatric risk genes predict brain structure at birth. Cereb Cortex 2014; 24: 1230-1246
8. Bunce D, Bielak AA, Anstey KJ, Cherbuin N, Batterham PJ, Easteal S. APOE genotype and cognitive change in young, middle-Aged, and older adults living in the community. J Gerontol A Biol Sci Med Sci 2014; 69: 379-386
9. Jochemsen HM, Muller M, van der Graaf Y, Geerlings MI. APOE epsilon4 differentially influences change in memory performance depending on age. The SMART-MR Study. Neurobiol Aging 2012; 33: e815-e822
10. Evans S, Dowell NG, Tabet N, Tofts PS, King SL, Rusted JM. Cognitive and neural signatures of the APOE E4 allele in mid-Aged adults. Neurobiol Aging 2014; 35: 1615-1623
11. Alexander DM, Williams LM, Gatt JM, et al. The contribution of apolipoprotein E alleles on cognitive performance and dynamic neural activity over six decades. Biol Psychol 2007; 75: 229-238
12. Bloss CS, Delis DC, Salmon DP, Bondi MW. APOE genotype is associated with left-handedness and visuospatial skills in children. Neurobiol Aging 2010; 31: 787-795
13. Taylor AE, Guthrie PA, Smith GD, et al. IQ, educational attainment, memory and plasma lipids: associations with apolipoprotein E genotype in 5995 children. Biol Psychiatry 2011; 70: 152-158
14. Bloss CS, Delis DC, Salmon DP, Bondi MW. Decreased cognition in children with risk factors for Alzheimer's disease. Biol Psychiatry 2008; 64: 904-906
15. Farrer LA, Cupples LA, Haines JL, et al. Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease: a meta-Analysis. APOE and Alzheimer Disease Meta Analysis Consortium. JAMA 1997; 278: 1349-1356
16. Berlau DJ, Kahle-Wrobleski K, Head E, GoodusM, Kim R, Kawas C. Dissociation of neuropathologic findings and cognition: case report of an apolipoprotein E epsilon2/epsilon2 genotype. Arch Neurol 2007; 64: 1193-1196
17. Suri S, Heise V, Trachtenberg AJ, Mackay CE The forgotten APOE allele: a review of the evidence and suggested mechanisms for the protective effect of APOE epsilon2. Neurosci Biobehav Rev 2013 37 2878-2886
18. Morris JC, Roe CM, Xiong C, et al. APOE predicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging. Ann Neurol 2010; 67: 122-131
19. Liu Y, Paajanen T, Westman E, et al. APOE epsilon2 allele is associated with larger regional cortical thicknesses and volumes. Dement Geriatr Cogn Disord 2010; 30: 229-237
20. den Heijer T, Oudkerk M, Launer LJ, van Duijn CM, Hofman A, Breteler MM. Hippocampal, amygdalar, and global brain atrophy in different apolipoprotein E genotypes. Neurology 2002; 59: 746-748
21. Bunce D, Anstey KJ, Cherbuin N, Gautam P, Sachdev P, Easteal S. APOE genotype and entorhinal cortex volume in non-demented community-dwelling adults in midlife and early old age. J Alzheimers Dis 2012; 30: 935-942
22. Jernigan TL, Brown TT, Hagler DJ Jr, et al. The Pediatric Imaging, Neurocognition, and Genetics (PING) data repository. Neuroimage 2015; 124: 1149-1154
23. Yap QJ, Teh I, Fusar-Poli P, Sum MY, Kuswanto C, Sim K. Tracking cerebral white matter changes across the lifespan: insights from diffusion tensor imaging studies. J Neural Transm 2013; 120: 1369-1395
24. Weintraub S, Dikmen SS, Heaton RK, et al. Cognition assessment using the NIH Toolbox. Neurology 2013; 80: S54-S64
25. Reinvang I, Winjevoll IL, Rootwelt H, Espeseth T. Working memory deficits in healthy APOE epsilon 4 carriers. Neuropsychologia 2010; 48: 566-573
26. Caselli RJ, Dueck AC, Locke DE, et al. Longitudinal modeling of frontal cognition in APOE epsilon4 homozygotes, heterozygotes, and noncarriers. Neurology 2011; 76: 1383-1388
27. Kantarci K, Lowe V, Przybelski SA, et al. APOE modifies the association between Abeta load and cognition in cognitively normal older adults. Neurology 2012; 78: 232-240
28. Aickin M, Gensler H. Adjusting for multiple testing when reporting research results: the Bonferroni vs Holm methods. Am J Public Health 1996; 86: 726-728
29. Fennema-Notestine C, Panizzon MS, Thompson WR, et al. Presence of ApoE epsilon4 allele associated with thinner frontal cortex in middle age. J Alzheimers Dis 2011; 26(suppl 3): 49-60
30. Liu Y, Paajanen T, Westman E, et al. Effect of APOE epsilon4 allele on cortical thicknesses and volumes: the AddNeuroMed Study. J Alzheimers Dis 2010; 21: 947-966
31. Hostage CA, Roy Choudhury K, Doraiswamy PM, Petrella JR; Alzheimer's Disease Neuroimaging Initiative. Dissecting the gene dose-effects of the APOE epsilon4 and epsilon2 alleles on hippocampal volumes in aging and Alzheimer's disease. PLoS One 2013; 8: e54483
32. Ostby Y, Tamnes CK, Fjell AM, Westlye LT, Due-Tonnessen P, Walhovd KB. Heterogeneity in subcortical brain development: a structural magnetic resonance imaging study of brain maturation from 8 to 30 years. J Neurosci 2009; 29: 11772-11782
33. Gogtay N, Giedd JN, Lusk L, et al. Dynamic mapping of human cortical development during childhood through early adulthood. Proc Natl Acad Sci USA 2004; 101: 8174-8179
34. Sowell E, Thompson P, Welcome S, Henkenius A, Toga A, Peterson B. Cortical abnormalities in children and adolescents with attention-deficit hyperactivity disorder. Lancet 2003; 362: 1699-1707
35. Rifkin-Graboi A, Bai J, Chen H, et al. Prenatal maternal depression associates with microstructure of right amygdala in neonates at birth. Biol Psychiatry 2013; 74: 837-844
36. Treit S, Zhou D, Lebel C, Rasmussen C, Andrew G, Beaulieu C. Longitudinal MRI reveals impaired cortical thinning in children and adolescents prenatally exposed to alcohol. Hum Brain Mapp 2014; 35: 4892-4903
37. Hua X, Leow AD, Parikshak N, et al. Tensor-based morphometry as a neuroimaging biomarker for Alzheimer's disease: an MRI study of 676 AD, MCI, and normal subjects. Neuroimage 2008; 43: 458-469
38. Berlau DJ, Corrada MM, Head E, Kawas CH. APOE epsilon2 is associated with intact cognition but increased Alzheimer pathology in the oldest old. Neurology 2009; 72: 829-834
39. Chiang GC, Zhan W, Schuff N, Weiner MW. White matter alterations in cognitively normal apoE epsilon2 carriers: insight into Alzheimer resistance? AJNR Am J Neuroradiol 2012; 33: 1392-1397
40. Khan W, Giampietro V, Ginestet C, et al. No differences in hippocampal volume between carriers and non-carriers of the ApoE epsilon4 and epsilon2 alleles in young healthy adolescents. J Alzheimers Dis 2014; 40: 37-43