-
1
-
-
42949163491
-
Mechanisms of hepatic fibrogenesis
-
Friedman, SL (2008). Mechanisms of hepatic fibrogenesis. Gastroenterology 134: 1655-1669
-
(2008)
Gastroenterology
, vol.134
, pp. 1655-1669
-
-
Friedman, S.L.1
-
3
-
-
83455259787
-
Update on hepatic stellate cells: Pathogenic role in liver fibrosis and novel isolation techniques
-
Tacke, F and Weiskirchen, R (2012). Update on hepatic stellate cells: pathogenic role in liver fibrosis and novel isolation techniques. Expert Rev Gastroenterol Hepatol 6: 67-80
-
(2012)
Expert Rev Gastroenterol Hepatol
, vol.6
, pp. 67-80
-
-
Tacke, F.1
Weiskirchen, R.2
-
5
-
-
84896806249
-
Liver fibrosis and repair: Immune regulation of wound healing in a solid organ
-
Pellicoro, A, Ramachandran, P, Iredale, JP and Fallowfield, JA (2014). Liver fibrosis and repair: immune regulation of wound healing in a solid organ. Nat Rev Immunol 14: 181-194
-
(2014)
Nat Rev Immunol
, vol.14
, pp. 181-194
-
-
Pellicoro, A.1
Ramachandran, P.2
Iredale, J.P.3
Fallowfield, J.A.4
-
6
-
-
84877141184
-
Evolving therapies for liver fibrosis
-
Schuppan, D and Kim, YO (2013). Evolving therapies for liver fibrosis. J Clin Invest 123: 1887-1901
-
(2013)
J Clin Invest
, vol.123
, pp. 1887-1901
-
-
Schuppan, D.1
Kim, Y.O.2
-
7
-
-
24644446398
-
Ribo-gnome: The big world of small RNAs
-
Zamore, PD and Haley, B (2005). Ribo-gnome: the big world of small RNAs. Science 309: 1519-1524
-
(2005)
Science
, vol.309
, pp. 1519-1524
-
-
Zamore, P.D.1
Haley, B.2
-
8
-
-
79551541594
-
The progression of liver fibrosis is related with overexpression of the miR-199 and 200 families
-
Murakami, Y, Toyoda, H, Tanaka, M, Kuroda, M, Harada, Y, Matsuda, F et al. (2011). The progression of liver fibrosis is related with overexpression of the miR-199 and 200 families. PLoS One 6: e16081
-
(2011)
PLoS One
, vol.6
, pp. e16081
-
-
Murakami, Y.1
Toyoda, H.2
Tanaka, M.3
Kuroda, M.4
Harada, Y.5
Matsuda, F.6
-
11
-
-
75149141045
-
MeCP2 controls an epigenetic pathway that promotes myofibroblast transdifferentiation and fibrosis
-
714.e1
-
Mann, J, Chu, DC, Maxwell, A, Oakley, F, Zhu, NL, Tsukamoto, H et al. (2010). MeCP2 controls an epigenetic pathway that promotes myofibroblast transdifferentiation and fibrosis. Gastroenterology 138: 705-14, 714.e1
-
(2010)
Gastroenterology
, vol.138
, pp. 705-714
-
-
Mann, J.1
Chu, D.C.2
Maxwell, A.3
Oakley, F.4
Zhu, N.L.5
Tsukamoto, H.6
-
12
-
-
78751476297
-
Micro-RNA profiling reveals a role for miR-29 in human and murine liver fibrosis
-
Roderburg, C, Urban, GW, Bettermann, K, Vucur, M, Zimmermann, H, Schmidt, S et al. (2011). Micro-RNA profiling reveals a role for miR-29 in human and murine liver fibrosis. Hepatology 53: 209-218
-
(2011)
Hepatology
, vol.53
, pp. 209-218
-
-
Roderburg, C.1
Urban, G.W.2
Bettermann, K.3
Vucur, M.4
Zimmermann, H.5
Schmidt, S.6
-
13
-
-
80051784270
-
Suppression of hepatic stellate cell activation by microRNA-29b.
-
Sekiya, Y, Ogawa, T, Yoshizato, K, Ikeda, K and Kawada, N (2011). Suppression of hepatic stellate cell activation by microRNA-29b. Biochem Biophys Res Commun 412: 74-79
-
(2011)
Biochem Biophys Res Commun
, vol.412
, pp. 74-79
-
-
Sekiya, Y.1
Ogawa, T.2
Yoshizato, K.3
Ikeda, K.4
Kawada, N.5
-
14
-
-
79957515102
-
Hepatitis C virus infection and hepatic stellate cell activation downregulate miR-29: MiR-29 overexpression reduces hepatitis C viral abundance in culture
-
Bandyopadhyay, S, Friedman, RC, Marquez, RT, Keck, K, Kong, B, Icardi, MS et al. (2011). Hepatitis C virus infection and hepatic stellate cell activation downregulate miR-29: miR-29 overexpression reduces hepatitis C viral abundance in culture. J Infect Dis 203: 1753-1762
-
(2011)
J Infect Dis
, vol.203
, pp. 1753-1762
-
-
Bandyopadhyay, S.1
Friedman, R.C.2
Marquez, R.T.3
Keck, K.4
Kong, B.5
Icardi, M.S.6
-
15
-
-
84877258007
-
Treatment of HCV infection by targeting microRNA
-
Janssen, HL, Reesink, HW, Lawitz, EJ, Zeuzem, S, Rodriguez-Torres, M, Patel, K et al. (2013). Treatment of HCV infection by targeting microRNA. N Engl J Med 368: 1685-1694
-
(2013)
N Engl J Med
, vol.368
, pp. 1685-1694
-
-
Janssen, H.L.1
Reesink, H.W.2
Lawitz, E.J.3
Zeuzem, S.4
Rodriguez-Torres, M.5
Patel, K.6
-
16
-
-
84892741671
-
Effect of an RNA interference drug on the synthesis of proprotein convertase subtilisin/kexin type 9 (PCSK9) and the concentration of serum LDL cholesterol in healthy volunteers: A randomised, single-blind, placebo-controlled, phase 1 trial
-
Fitzgerald, K, Frank-Kamenetsky, M, Shulga-Morskaya, S, Liebow, A, Bettencourt, BR, Sutherland, JE et al. (2014). Effect of an RNA interference drug on the synthesis of proprotein convertase subtilisin/kexin type 9 (PCSK9) and the concentration of serum LDL cholesterol in healthy volunteers: a randomised, single-blind, placebo-controlled, phase 1 trial. Lancet 383: 60-68
-
(2014)
Lancet
, vol.383
, pp. 60-68
-
-
Fitzgerald, K.1
Frank-Kamenetsky, M.2
Shulga-Morskaya, S.3
Liebow, A.4
Bettencourt, B.R.5
Sutherland, J.E.6
-
17
-
-
84919860979
-
Soluble FGL2, a novel effector molecule of activated hepatic stellate cells, regulates T-cell function in cirrhotic patients with hepatocellular carcinoma
-
Sun, Y, Xi, D, Ding, W, Wang, F, Zhou, H and Ning, Q (2014). Soluble FGL2, a novel effector molecule of activated hepatic stellate cells, regulates T-cell function in cirrhotic patients with hepatocellular carcinoma. Hepatol Int 8: 567-575
-
(2014)
Hepatol Int
, vol.8
, pp. 567-575
-
-
Sun, Y.1
Xi, D.2
Ding, W.3
Wang, F.4
Zhou, H.5
Ning, Q.6
-
18
-
-
79959826381
-
Extracellular matrix dynamics in hepatocarcinogenesis: A comparative proteomics study of PDGFC transgenic and Pten null mouse models
-
Lai, KK, Shang, S, Lohia, N, Booth, GC, Masse, DJ, Fausto, N et al. (2011). Extracellular matrix dynamics in hepatocarcinogenesis: a comparative proteomics study of PDGFC transgenic and Pten null mouse models. PLoS Genet 7: e1002147
-
(2011)
PLoS Genet
, vol.7
, pp. e1002147
-
-
Lai, K.K.1
Shang, S.2
Lohia, N.3
Booth, G.C.4
Masse, D.J.5
Fausto, N.6
-
19
-
-
84863002362
-
Expression of platelet-derived growth factor-C and insulin-like growth factor i in hepatic stellate cells is inhibited by miR-29
-
Kwiecinski, M, Elfimova, N, Noetel, A, Tox, U, Steffen, HM, Hacker, U et al. (2012). Expression of platelet-derived growth factor-C and insulin-like growth factor I in hepatic stellate cells is inhibited by miR-29. Lab Invest 92: 978-987
-
(2012)
Lab Invest
, vol.92
, pp. 978-987
-
-
Kwiecinski, M.1
Elfimova, N.2
Noetel, A.3
Tox, U.4
Steffen, H.M.5
Hacker, U.6
-
20
-
-
65949106130
-
Orally delivered siRNA targeting macrophage Map4k4 suppresses systemic inflammation
-
Aouadi, M, Tesz, GJ, Nicoloro, SM, Wang, M, Chouinard, M, Soto, E et al. (2009). Orally delivered siRNA targeting macrophage Map4k4 suppresses systemic inflammation. Nature 458: 1180-1184
-
(2009)
Nature
, vol.458
, pp. 1180-1184
-
-
Aouadi, M.1
Tesz, G.J.2
Nicoloro, S.M.3
Wang, M.4
Chouinard, M.5
Soto, E.6
-
21
-
-
19544389673
-
Mechanisms of nitric oxide interplay with Rho GTPase family members in modulation of actin membrane dynamics in pericytes and fibroblasts
-
Lee, JS, Kang Decker, N, Chatterjee, S, Yao, J, Friedman, S and Shah, V (2005). Mechanisms of nitric oxide interplay with Rho GTPase family members in modulation of actin membrane dynamics in pericytes and fibroblasts. Am J Pathol 166: 1861-1870
-
(2005)
Am J Pathol
, vol.166
, pp. 1861-1870
-
-
Lee, J.S.1
Kang Decker, N.2
Chatterjee, S.3
Yao, J.4
Friedman, S.5
Shah, V.6
-
22
-
-
84865463143
-
Protein disulfide isomerase is required for platelet-derived growth factor-induced vascular smooth muscle cell migration, Nox1 NADPH oxidase expression, and RhoGTPase activation
-
Pescatore, LA, Bonatto, D, Forti, FL, Sadok, A, Kovacic, H and Laurindo, FR (2012). Protein disulfide isomerase is required for platelet-derived growth factor-induced vascular smooth muscle cell migration, Nox1 NADPH oxidase expression, and RhoGTPase activation. J Biol Chem 287: 29290-29300
-
(2012)
J Biol Chem
, vol.287
, pp. 29290-29300
-
-
Pescatore, L.A.1
Bonatto, D.2
Forti, F.L.3
Sadok, A.4
Kovacic, H.5
Laurindo, F.R.6
-
23
-
-
21744459448
-
Differential regulation of platelet-derived growth factor stimulated migration and proliferation in osteoblastic cells
-
Mehrotra, M, Krane, SM, Walters, K and Pilbeam, C (2004). Differential regulation of platelet-derived growth factor stimulated migration and proliferation in osteoblastic cells. J Cell Biochem 93: 741-752
-
(2004)
J Cell Biochem
, vol.93
, pp. 741-752
-
-
Mehrotra, M.1
Krane, S.M.2
Walters, K.3
Pilbeam, C.4
-
24
-
-
0041529686
-
Protein kinase A blocks Raf-1 activity by stimulating 14-3-3 binding and blocking Raf-1 interaction with Ras
-
Dumaz, N and Marais, R (2003). Protein kinase A blocks Raf-1 activity by stimulating 14-3-3 binding and blocking Raf-1 interaction with Ras. J Biol Chem 278: 29819-29823
-
(2003)
J Biol Chem
, vol.278
, pp. 29819-29823
-
-
Dumaz, N.1
Marais, R.2
-
25
-
-
1642297200
-
Myocardin and ternary complex factors compete for SRF to control smooth muscle gene expression
-
Wang, Z, Wang, DZ, Hockemeyer, D, McAnally, J, Nordheim, A and Olson, EN (2004). Myocardin and ternary complex factors compete for SRF to control smooth muscle gene expression. Nature 428: 185-189
-
(2004)
Nature
, vol.428
, pp. 185-189
-
-
Wang, Z.1
Wang, D.Z.2
Hockemeyer, D.3
McAnally, J.4
Nordheim, A.5
Olson, E.N.6
-
26
-
-
84961588319
-
MAP4K4 promotes epithelial-mesenchymal transition and metastasis in hepatocellular carcinoma
-
epub ahead of print
-
Feng, XJ, Pan, Q, Wang, SM, Pan, YC, Wang, Q, Zhang, HH et al. (2016). MAP4K4 promotes epithelial-mesenchymal transition and metastasis in hepatocellular carcinoma. Tumour Biol (epub ahead of print)
-
(2016)
Tumour Biol
-
-
Feng, X.J.1
Pan, Q.2
Wang, S.M.3
Pan, Y.C.4
Wang, Q.5
Zhang, H.H.6
-
27
-
-
79951819984
-
ShRNA-targeted MAP4K4 inhibits hepatocellular carcinoma growth
-
Liu, AW, Cai, J, Zhao, XL, Jiang, TH, He, TF, Fu, HQ et al. (2011). ShRNA-targeted MAP4K4 inhibits hepatocellular carcinoma growth. Clin Cancer Res 17: 710-720
-
(2011)
Clin Cancer Res
, vol.17
, pp. 710-720
-
-
Liu, A.W.1
Cai, J.2
Zhao, X.L.3
Jiang, T.H.4
He, T.F.5
Fu, H.Q.6
-
28
-
-
38049083888
-
Primer: Inflammasomes and interleukin 1beta in inflammatory disorders
-
Church, LD, Cook, GP and McDermott, MF (2008). Primer: inflammasomes and interleukin 1beta in inflammatory disorders. Nat Clin Pract Rheumatol 4: 34-42
-
(2008)
Nat Clin Pract Rheumatol
, vol.4
, pp. 34-42
-
-
Church, L.D.1
Cook, G.P.2
McDermott, M.F.3
-
29
-
-
34047121535
-
Expression of MMPs and TIMPs in liver fibrosis-A systematic review with special emphasis on anti-fibrotic strategies
-
Hemmann, S, Graf, J, Roderfeld, M and Roeb, E (2007). Expression of MMPs and TIMPs in liver fibrosis-A systematic review with special emphasis on anti-fibrotic strategies. J Hepatol 46: 955-975
-
(2007)
J Hepatol
, vol.46
, pp. 955-975
-
-
Hemmann, S.1
Graf, J.2
Roderfeld, M.3
Roeb, E.4
-
30
-
-
33845705732
-
Overexpression of NDRG1 is an indicator of poor prognosis in hepatocellular carcinoma
-
Chua, MS, Sun, H, Cheung, ST, Mason, V, Higgins, J, Ross, DT et al. (2007). Overexpression of NDRG1 is an indicator of poor prognosis in hepatocellular carcinoma. Mod Pathol 20: 76-83
-
(2007)
Mod Pathol
, vol.20
, pp. 76-83
-
-
Chua, M.S.1
Sun, H.2
Cheung, S.T.3
Mason, V.4
Higgins, J.5
Ross, D.T.6
-
31
-
-
0028936897
-
Experimental studies on bone inducing activity of composites of atelopeptide type i collagen as a carrier for ectopic osteoinduction by rhBMP-2
-
Fujimura, K, Bessho, K, Kusumoto, K, Ogawa, Y and Iizuka, T (1995). Experimental studies on bone inducing activity of composites of atelopeptide type I collagen as a carrier for ectopic osteoinduction by rhBMP-2. Biochem Biophys Res Commun 208: 316-322
-
(1995)
Biochem Biophys Res Commun
, vol.208
, pp. 316-322
-
-
Fujimura, K.1
Bessho, K.2
Kusumoto, K.3
Ogawa, Y.4
Iizuka, T.5
-
32
-
-
3242733298
-
Atelocollagen-mediated synthetic small interfering RNA delivery for effective gene silencing in vitro and in vivo
-
Minakuchi, Y, Takeshita, F, Kosaka, N, Sasaki, H, Yamamoto, Y, Kouno, M et al. (2004). Atelocollagen-mediated synthetic small interfering RNA delivery for effective gene silencing in vitro and in vivo. Nucleic Acids Res 32: e109
-
(2004)
Nucleic Acids Res
, vol.32
, pp. e109
-
-
Minakuchi, Y.1
Takeshita, F.2
Kosaka, N.3
Sasaki, H.4
Yamamoto, Y.5
Kouno, M.6
-
33
-
-
84870383902
-
The role of surface charge in cellular uptake and cytotoxicity of medical nanoparticles
-
Frohlich, E (2012). The role of surface charge in cellular uptake and cytotoxicity of medical nanoparticles. Int J Nanomedicine 7: 5577-5591
-
(2012)
Int J Nanomedicine
, vol.7
, pp. 5577-5591
-
-
Frohlich, E.1
-
34
-
-
84861437351
-
Protection from liver fibrosis by a peroxisome proliferator-Activated receptor agonist
-
Iwaisako, K, Haimerl, M, Paik, YH, Taura, K, Kodama, Y, Sirlin, C et al. (2012). Protection from liver fibrosis by a peroxisome proliferator-Activated receptor agonist. Proc Natl Acad Sci USA 109: E1369-E1376
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. E1369-E1376
-
-
Iwaisako, K.1
Haimerl, M.2
Paik, Y.H.3
Taura, K.4
Kodama, Y.5
Sirlin, C.6
-
35
-
-
84901922571
-
Effects of oral intake of hydrogen water on liver fibrogenesis in mice
-
Koyama, Y, Taura, K, Hatano, E, Tanabe, K, Yamamoto, G, Nakamura, K et al. (2014). Effects of oral intake of hydrogen water on liver fibrogenesis in mice. Hepatol Res 44: 663-677
-
(2014)
Hepatol Res
, vol.44
, pp. 663-677
-
-
Koyama, Y.1
Taura, K.2
Hatano, E.3
Tanabe, K.4
Yamamoto, G.5
Nakamura, K.6
-
36
-
-
74149083873
-
Systemic delivery of synthetic microRNA-16 inhibits the growth of metastatic prostate tumors via downregulation of multiple cell-cycle genes
-
Takeshita, F, Patrawala, L, Osaki, M, Takahashi, RU, Yamamoto, Y, Kosaka, N et al. (2010). Systemic delivery of synthetic microRNA-16 inhibits the growth of metastatic prostate tumors via downregulation of multiple cell-cycle genes. Mol Ther 18: 181-187
-
(2010)
Mol Ther
, vol.18
, pp. 181-187
-
-
Takeshita, F.1
Patrawala, L.2
Osaki, M.3
Takahashi, R.U.4
Yamamoto, Y.5
Kosaka, N.6
-
37
-
-
84925308488
-
Cytoglobin deficiency promotes liver cancer development from hepatosteatosis through activation of the oxidative stress pathway
-
Thuy, le TT, Matsumoto, Y, Thuy, TT, Hai, H, Suoh, M, Urahara, Y et al. (2015). Cytoglobin deficiency promotes liver cancer development from hepatosteatosis through activation of the oxidative stress pathway. Am J Pathol 185: 1045-1060
-
(2015)
Am J Pathol
, vol.185
, pp. 1045-1060
-
-
Thuy Le, T.T.1
Matsumoto, Y.2
Thuy, T.T.3
Hai, H.4
Suoh, M.5
Urahara, Y.6
-
38
-
-
10844242987
-
Human hepatic stellate cell lines, LX-1 and LX-2: New tools for analysis of hepatic fibrosis
-
Xu, L, Hui, AY, Albanis, E, Arthur, MJ, O'Byrne, SM, Blaner, WS et al. (2005). Human hepatic stellate cell lines, LX-1 and LX-2: new tools for analysis of hepatic fibrosis. Gut 54: 142-151
-
(2005)
Gut
, vol.54
, pp. 142-151
-
-
Xu, L.1
Hui, A.Y.2
Albanis, E.3
Arthur, M.J.4
O'Byrne, S.M.5
Blaner, W.S.6
|