The Central domain of RyR1 is the transducer for long-range allosteric gating of channel opening

Cell Research

Volumn 26, Issue 9, 2016, Pages 995-1006

  Bai, Xiao Chen ^a   Yan, Zhen ^b   Wu, Jianping ^b   Li, Zhangqiang ^b   Yan, Nieng ^b  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

^b TSINGHUA UNIVERSITY   (China)

Author keywords

calcium channel; excitation contraction coupling; membrane transport; RyR1; voltage gated calcium channels

Indexed keywords

RYANODINE RECEPTOR;

ALLOSTERISM; ANIMAL; CHANNEL GATING; CHEMISTRY; CRYOELECTRON MICROSCOPY; CYTOPLASM; EXCITATION CONTRACTION COUPLING; LEPORIDAE; METABOLISM; MOLECULAR MODEL; PROTEIN DOMAIN; STRUCTURE ACTIVITY RELATION; ULTRASTRUCTURE;

ALLOSTERIC REGULATION; ANIMALS; CRYOELECTRON MICROSCOPY; CYTOPLASM; EXCITATION CONTRACTION COUPLING; ION CHANNEL GATING; MODELS, MOLECULAR; PROTEIN DOMAINS; RABBITS; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84980015412     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/cr.2016.89     Document Type: Article

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