Changes in Cognitive Function Following Bariatric Surgery: a Systematic Review

Obesity Surgery

Volumn 26, Issue 10, 2016, Pages 2530-2537

  Handley, Joel D ^a   Williams, David M ^b   Caplin, Scott ^c   Stephens, Jeffrey W ^d   Barry, Jonathan ^c  

^a UNIVERSITY HOSPITAL OF WALES   (United Kingdom)

^b Bronglais General Hospital   (United Kingdom)

^c MORRISTON HOSPITAL   (United Kingdom)

^d SWANSEA UNIVERSITY   (United Kingdom)

Author keywords

Alzheimer s; Alzheimer s disease; Bariatric surgery; Cognition; Cognitive function; Dementia; Gastric band; Gastric bypass; Gastric surgery; Memory; Roux en Y; Sleeve gastrectomy and weight loss surgery; Systematic review

Indexed keywords

ATTENTION; BARIATRIC SURGERY; COCHRANE LIBRARY; COGNITION; COMORBIDITY; EMBASE; EXECUTIVE FUNCTION; GASTRIC BANDING; GASTRIC BYPASS SURGERY; GASTROPLASTY; HUMAN; LEARNING; MEDLINE; MEMORY; NONHUMAN; PHYSICAL ACTIVITY; PRIORITY JOURNAL; PUBLICATION; RANDOMIZED CONTROLLED TRIAL (TOPIC); RECALL; RECOGNITION; REVIEW; RODENT MODEL; SCOPUS; SYSTEMATIC REVIEW; THIAMINE DEFICIENCY; VERTICAL BANDED GASTROPLASTY; WEIGHT REDUCTION; COGNITIVE DEFECT; COMPLICATION; OBESITY; PHYSIOLOGY; PSYCHOLOGY;

BARIATRIC SURGERY; COGNITION; COGNITION DISORDERS; HUMANS; OBESITY; WEIGHT LOSS;

EID: 84979997941     PISSN: 09608923     EISSN: 17080428     Source Type: Journal    
DOI: 10.1007/s11695-016-2312-z     Document Type: Review

References (67)

1. Cournot M, Marquié JC, Ansiau D, et al. Relation between body mass index and cognitive function in healthy middle-aged men and women. Neurology. 2006;67(7):1208–14.
2. Gunstad J, Lhotsky A, Wendell CR, Ferrucci L, Zonderman AB. Longitudinal examination of obesity and cognitive function: results from the Baltimore longitudinal study of aging. Neuroepidemiology. 2010;34(4):222–9.
3. Verdejo-García A, Pérez-Expósito M, Schmidt-Río-Valle J, et al. Selective alterations within executive functions in adolescents with excess weight. Obesity. 2010;18(8):1572–8.
4. Fergenbaum JH, Bruce S, Lou W, Hanley AJ, Greenwood C, Young TK. Obesity and lowered cognitive performance in a Canadian first nations population. Obesity. 2009;17(10):1957–63.
5. Sellbom KS, Gunstad J. Cognitive function and decline in obesity. J Alzheimers Dis. 2012;30(2):89–95.
6. Prickett C, Brennan L, Stolwyk R. Examining the relationship between obesity and cognitive function: a systematic literature review. Obes Res Clin Pract. 2015;9(2):93–113.
7. Lokken KL, Boeka AG, Yellumahanthi K, Wesley M, Clements RH. Cognitive performance of morbidly obese patients seeking bariatric surgery. Am Surg. 2010;76(1):55–9.
8. Siervo M, Arnold R, Wells JC, et al. Intentional weight loss in overweight and obese individuals and cognitive function: a systematic review and meta-analysis. Obes Rev. 2011;12(11):968–83.
9. Bastard JP, Maachi M, Lagathu C, et al. Recent advances in the relationship between obesity, inflammation, and insulin resistance. Eur Cytokine Netw. 2006;17(1):4–12.
10. Sweat V, Starr V, Bruehl H, et al. C-reactive protein is linked to lower cognitive performance in overweight and obese women. Inflammation. 2008;31(3):198–207.
11. Dimitriadis E, Daskalakis M, Kampa M, Peppe A, Papadakis JA, Melissas J. Alterations in gut hormones after laparoscopic sleeve gastrectomy: a prospective clinical and laboratory investigational study. Ann Surg. 2013;257(4):647–54.
12. Ghanim H, Monte SV, Sia CL, Abuaysheh S, Green K, Caruana JA, et al. Reduction in inflammation and the expression of amyloid precursor protein and other proteins related to Alzheimer’s disease following gastric bypass surgery. J Clin Endocrinol Metab. 2012;97(7):1197–201.
13. Profenno LA, Porsteinsson AP, Faraone SV. Meta-analysis of Alzheimer’s disease risk with obesity, diabetes, and related disorders. Biol Psychiatry. 2010;67(6):505–12.
14. Guldstrand M, Ahrén B, Wredling R, Backman L, Lins PE, Adamson U. Alteration of the counterregulatory responses to insulin-induced hypoglycemia and of cognitive function after massive weight reduction in severely obese subjects. Metabolism. 2003;52(7):900–7.
15. Marques EL, Halpern A, Corrêa Mancini M, et al. Changes in neuropsychological tests and brain metabolism after bariatric surgery. J Clin Endocrinol Metab. 2014;99(11):2347–52.
16. Gunstad J, Strain G, Devlin MJ, et al. Improved memory function 12 weeks after bariatric surgery. Surg Obes Relat Dis. 2011;7(4):465–72.
17. Miller LA, Crosby RD, Galioto R, et al. Bariatric surgery patients exhibit improved memory function 12 months post-operatively. Obes Surg. 2013;23(10):1527–35.
18. Alosco ML, Spitznagel MB, Strain G, et al. Improved memory function two years after bariatric surgery. Obesity. 2014;22(1):32–8.
19. Alosco ML, Galioto R, Spitznagel MB, et al. Cognitive function after bariatric surgery: evidence for improvement 3 years after surgery. Am J Surg. 2014;207(6):870–6.
20. Morton J, Boussard T. Gastric bypass improves cognition. Obes Surg. 2009;19(8):970.
21. Sousa S, Ribeiro O, Horácio JG, Faísca L. Executive functions in patients seeking and undergoing bariatric surgery. Psic Saúde Doenças. 2012;13(2):389–98.
22. Georgiadou E, Gruner-Labitzke K, Köhler H, de Zwaan M, Müller A. Cognitive function and nonfood-related impulsivity in post-bariatric surgery patients. Front Psychol. 2014;5:1502.
23. Spitznagel MB, Alosco M, Strain G, et al. Cognitive function predicts 24-month weight loss success after bariatric surgery. Surg Obes Relat Dis. 2013;9(5):765–70.
24. Lavender JM, Alosco ML, Spitznagel MB, et al. Association between binge eating disorder and changes in cognitive functioning following bariatric surgery. J Psychiatr Res. 2014;59:148–54.
25. Spitznagel MB, Alosco M, Galioto R, et al. The role of cognitive function in postoperative weight loss outcomes: 36-month follow-up. Obes Surg. 2014;24(7):1078–84.
26. Alosco ML, Spitznagel MB, Strain G, et al. The effects of cystatin C and alkaline phosphatase changes on cognitive function 12-months after bariatric surgery. J Neurol Sci. 2014;345(1–2):176–80.
27. Alosco ML, Cohen R, Spitznagel MB, et al. Older age does not limit post-bariatric surgery cognitive benefits: a preliminary investigation. Surg Obes Relat Dis. 2014;10(6):1196–201.
28. Alosco ML, Spitznagel MB, Strain G, Devlin M, Crosby RD, Mitchell JE, Gunstad J. Family history of Alzheimer’s disease limits improvement in cognitive function after bariatric surgery. SAGE Open Medicine 2014;2.
29. Alosco ML, Spitznagel MB, Strain G, et al. Pre-operative history of depression and cognitive changes in bariatric surgery patients. Psychol Health Med. 2015;20(7):802–13.
30. Alosco ML, Spitznagel MB, Strain G, et al. Improved serum leptin and ghrelin following bariatric surgery predict better postoperative cognitive function. J Clin Neurol. 2015;11(1):48–56.
31. Hawkins MA, Alosco ML, Spitznagel MB, et al. The association between reduced inflammation and cognitive gains after bariatric surgery. Psychosom Med. 2015;77(6):688–96.
32. Higgins JP, Green S. Cochrane handbook for systematic reviews of interventions. London: Wiley; 2008.
33. Ashrafian H, Harling L, Darzi A, Athanasiou T. Neurodegenerative disease and obesity: what is the role of weight loss and bariatric interventions? Metab Brain Dis. 2013;28(3):341–53.
34. Stanek KM, Gunstad J. Can bariatric surgery reduce risk of Alzheimer’s disease? Prog Neuropsychopharmacol Biol Psychiatry. 2013;47:135–9.
35. Haley AP, Alosco ML, Gunstad J. Surgical and nonsurgical interventions for obesity in service of preserving cognitive function. Psychosom Med. 2015;77(6):679–87.
36. Spitznagel MB, Hawkins M, Alosco M, et al. Neurocognitive effects of obesity and bariatric surgery. Eur Eat Disord Rev 2015.
37. Drevets WC. Prefrontal cortical-amygdalar metabolism in major depression. Ann N Y Acad Sci. 1999;877:614–37.
38. Chepenik LG, Cornew LA, Farah MJ. The influence of sad mood on cognition. Emotion. 2007;7(4):802–11.
39. Malik S, Mitchell JE, Engel S, Crosby R, Wonderlich S. Psychopathology in bariatric surgery candidates: a review of studies using structured diagnostic interviews. Compr Psychiatry. 2014;55(2):248–59.
40. Wing RR, Epstein LH, Marcus MD, Kupfer DJ. Mood changes in behavioral weight loss programs. J Psychosom Res. 1984;28(3):189–96.
41. Faulconbridge LF, Wadden TA, Berkowitz RI, et al. Changes in symptoms of depression with weight loss: results of a randomized trial. Obesity. 2009;17(5):1009–16.
42. de Zwaan M, Enderle J, Wagner S, Muhlhans B, Ditzen B, Gefeller O, et al. Anxiety and depression in bariatric surgery patients: a prospective, follow-up study using structured clinical interviews. J Affect Disord. 2011;133(1–2):61–8.
43. Burgmer R, Legenbauer T, Müller A, de Zwaan M, Fischer C, Herpertz S. Psychological outcome 4 years after restrictive bariatric surgery. Obes Surg. 2014;24(10):1670–8.
44. Colcombe S, Kramer AF. Fitness effects on the cognitive function of older adults: a meta-analytic study. Psychol Sci. 2003;14(2):125–30.
45. Hillman CH, Erickson KI, Kramer AF. Be smart, exercise your heart: exercise effects on brain and cognition. Nat Rev Neurosci. 2008;9(1):58–65.
46. King WC, Hsu JY, Belle SH, et al. Pre- to postoperative changes in physical activity: re-port from the longitudinal assessment of bariatric surgery-2 (LABS-2). Surg Obes Relat Dis. 2012;8(5):522–32.
47. Galioto R, King WC, Bond DS, et al. Physical activity and cognitive function in bariatric surgery candidates. Int J Neurosci. 2014;124(12):912–8.
48. Awad N, Gagnon M, Messier C. The relationship between impaired glucose tolerance, type 2 diabetes, and cognitive function. J Clin Exp Neuropsychol. 2004;26(8):1044–80.
49. Amenta F, Mignini F, Rabbia F, Tomassoni D, Veglio F. Protective effect of anti-hypertensive treatment on cognitive function in essential hypertension: analysis of published clinical data. J Neurol Sci. 2002;203–204:147–51.
50. Elias MF, Elias PK, Sullivan LM, Wolf PA, D’Agostino RB. Lower cognitive function in the presence of obesity and hypertension: the Framingham heart study. Int J Obes Relat Metab Disord. 2003;27(2):260–8.
51. Elias MF, Goodell AL, Dore GA. Hypertension and cognitive functioning: a perspective in historical context. Hypertension. 2012;60(2):260–8.
52. Kielb SA, Ancoli-Israel S, Rebok GW, Spira AP. Cognition in obstructive sleep apnea-hypopnea syndrome (OSAS): current clinical knowledge and the impact of treatment. Neuromol Med. 2012;14(3):180–93.
53. Alosco ML, Gunstad J. The negative effects of obesity and poor glycemic control on cognitive function: a proposed model for possible mechanisms. Curr Diab Rep. 2014;14(6):495.
54. Buchwald H, Estok R, Fahrbach K, Banel D, Jensen MD, Pories WJ, et al. Weight and type 2 diabetes after bariatric surgery: systematic review and meta-analysis. Am J Med. 2009;122(3):248–56.
55. Wilhelm SM, Young J, Kale-Pradhan PB. Effect of bariatric surgery on hypertension: a meta-analysis. Ann Pharmacother. 2014;48(6):674–82.
56. Buchwald H, Avidor Y, Braunwald E, Jensen MD, Pories W, Fahrbach K, et al. Bariatric surgery: a systematic review and meta-analysis. JAMA. 2004;292(14):1724–37.
57. Gunstad J, Paul RH, Cohen RA, Tate DF, Gordon E. Obesity is associated with memory deficits in young and middle-aged adults. Eat Weight Disord. 2006;11(1):15–9.
58. Gunstad J, Paul RH, Cohen RA, Tate DF, Spitznagel MB, Gordon E. Elevated body mass index is associated with executive dysfunction in otherwise healthy adults. Compr Psychiatry. 2007;48(1):57–61.
59. Graff-Radford J, Whitwell JL, Trenerry MR, et al. Focal brain atrophy in gastric bypass patients with cognitive complaints. J Clin Neurosci. 2011;18(12):1671–6.
60. Houdent C, Verger N, Courtois H, Ahtoy P, Ténière P. Wernicke’s encephalopathy after vertical banded gastroplasty for morbid obesity. Rev Med Interne. 2003;24(7):476–7.
61. Loh Y, Watson WD, Verma A, Chang ST, Stocker DJ, Labutta RJ. Acute Wernicke’s encephalopathy following bariatric surgery: clinical course and MRI correlation. Obes Surg. 2004;14:129–32.
62. Al-Fahad T, Ismael A, Soliman MO, Khoursheed M. Very early onset of Wernicke’s encephalopathy after gastric bypass. Obes Surg. 2006;16(5):671–2.
63. Becker DA, Ingala EE, Martinez-Lage M, Price RS, Galetta SL. Dry Beriberi and Wernicke’s encephalopathy following gastric lap band surgery. J Clin Neurosci. 2012;19(7):1050–2.
64. Aasheim ET. Wernicke encephalopathy after bariatric surgery: a systematic review. Ann Surg. 2008;248(5):714–20.
65. Scopinaro N, Adami GF, Marinari GM, et al. Biliopancreatic diversion. World J Surg. 1998;22(9):936–46.
66. Baltasar A, Bou R, Bengochea M, et al. 1,000 bariatric operations in a community setting. Obes Surg. 2006;6:409 [Abstract͔].
67. Grayson BE, Fitzgerald MF, Hakala-Finch AP, et al. Improvements in hippocampal-dependent memory and microglial infiltration with calorie restriction and gastric bypass surgery, but not with vertical sleeve gastrectomy. Int J Obes (Lond). 2014;38(3):349–56.