Natural killer cells phenotypic characterization as an outcome predictor of HCV-linked HCC after curative treatments

OncoImmunology

Volumn 5, Issue 8, 2016, Pages

  Cariani, Elisabetta ^a   Pilli, Massimo ^b   Barili, Valeria ^b   Porro, Emanuela ^b   Biasini, Elisabetta ^b   Olivani, Andrea ^b   Dalla Valle, Raffaele ^c   Trenti, Tommaso ^a   Ferrari, Carlo ^b   Missale, Gabriele ^b  

^a Ospedale Civile   (Italy)

^b UNIVERSITY HOSPITAL OF PARMA   (Italy)

^c UNIVERSITY OF PARMA   (Italy)

Author keywords

hepatitis C virus (HCV); Hepatocellular carcinoma (HCC); natural killer cells (NK); radiofrequency thermal ablation (RTA); surgical resection (SR)

Indexed keywords

CD3 ANTIGEN; GAMMA INTERFERON; LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; MEMBRANE RECEPTOR; NATURAL CYTOTOXIC RECEPTOR; PERFORIN; UNCLASSIFIED DRUG;

ADULT; ARTICLE; CANCER RECURRENCE; CAUCASIAN; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOTOXICITY; FEMALE; FLOW CYTOMETRY; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; MAJOR CLINICAL STUDY; MALE; NATURAL KILLER CELL; NONHUMAN; OUTCOME ASSESSMENT; OVERALL SURVIVAL; PERIPHERAL BLOOD MONONUCLEAR CELL; PHENOTYPE; PORTEIN EXPRESSION; REGULATORY MECHANISM;

EID: 84979964897     PISSN: 21624011     EISSN: 2162402X     Source Type: Journal    
DOI: 10.1080/2162402X.2016.1154249     Document Type: Article

References (24)

1. S.K.Larsen, Y.Gao, P.H.Basse. NK-cells in the tumor microenvironment. Crit Rev Oncog 2014; 19:91-105; PMID:24941376; http://dx.doi.org/10.1615/CritRevOncog.2014011142
2. A.Stojanovic, A.Cerwenka. Natural killer cells and solid tumors. J Innate Immun 2011; 3:355-64; PMID:21502747; http://dx.doi.org/10.1159/000325465
3. L.Cai, Z.Zhang, L.Zhou, H.Wang, J.Fu, S.Zhang, M.Shi, H.Zhang, Y.Yang, H.Wu et al. Functional impairment in circulating and intrahepatic NK-cells and relative mechanism in hepatocellular carcinoma patients. Clin Immunol 2008; 129:428-37; PMID:18824414; http://dx.doi.org/10.1016/j.clim.2008.08.012
4. Y.Wu, D.M.Kuang, W.D.Pan, Y.L.Wan, X.M.Lao, D.Wang, X.F.Li, L.Zheng. Monocyte/macrophage-elicited natural killer cell dysfunction in hepatocellular carcinoma is mediated by CD48/2B4 interactions. Hepatology 2013; 57:1107-16; PMID:23225218; http://dx.doi.org/10.1002/hep.26192
5. A.Taketomi, M.Shimada, K.Shirabe, K.Kajiyama, T.Gion, K.Sugimachi. Natural killer cell activity in patients with hepatocellular carcinoma:a new prognostic indicator after hepatectomy. Cancer 1998; 83:58-63; PMID:9655293; http://dx.doi.org/10.1002/(SICI)1097-0142(19980701)83:1%3c58::AID-CNCR8%3e3.0.CO;2-A
6. B.Hoechst, T.Voigtlaender, L.Ormandy, J.Gamrekelashvili, F.Zhao, H.Wedemeyer, F.Lehner, M.P.Manns, T.F.Greten, F.Korangy. Myeloid derived suppressor cells inhibit natural killer cells in patients with hepatocellular carcinoma via the NKp30 receptor. Hepatology 2009; 50:799-807; PMID:19551844; http://dx.doi.org/10.1002/hep.23054
7. F.Marras, F.Bozzano, M.L.Ascierto, A.De Maria. Baseline and dynamic expression of activating NK-cell receptors in the control of chronic viral infections:the paradigm of HIV-1 and HCV. Front Immunol 2014; 5:305; PMID:25071766; http://dx.doi.org/10.3389/fimmu.2014.00305
8. E.Cariani, G.Missale. KIR/HLA immunogenetic background influences the evolution of hepatocellular carcinoma. Oncoimmunol 2013; 2:e26622; PMID:24501686; http://dx.doi.org/10.4161/onci.26622
9. Y.P.Peng, Y.Zhu, J.J.Zhang, Z.K.Xu, Z.Y.Qian, C.C.Dai, K.R.Jiang, J.L.Wu, W.T.Gao, Q.Li et al. Comprehensive analysis of the percentage of surface receptors and cytotoxic granules positive natural killer cells in patients with pancreatic cancer, gastric cancer, and colorectal cancer. J Transl Med 2013; 11:262; PMID:24138752; http://dx.doi.org/10.1186/1479-5876-11-262
10. E.Mamessier, A.Sylvain, M.L.Thibult, G.Houvenaeghel, J.Jacquemier, R.Castellano, A.Gonçalves, P.André, F.Romagné, G.Thibault et al. Human breast cancer cells enhance self tolerance by promoting evasion from NK-cell antitumor immunity. J Clin Invest 2011; 121:3609-22; PMID:21841316; http://dx.doi.org/10.1172/JCI45816
11. H.Kamimura, S.Yamagiwa, A.Tsuchiya, M.Takamura, Y.Matsuda, S.Ohkoshi, M.Inoue, T.Wakai, Y.Shirai, M.Nomoto et al. Reduced NKG2D ligand expression in hepatocellular carcinoma correlates with early recurrence. J Hepatol 2012; 56:381-8; PMID:21756848; http://dx.doi.org/10.1016/j.jhep.2011.06.017
12. M.Jinushi, T.Takehara, T.Tatsumi, N.Hiramatsu, R.Sakamori, S.Yamaguchi, N.Hayashi. Impairment of natural killer cell and dendritic cell functions by the soluble form of MHC class I-related chain A in advanced human hepatocellular carcinomas. J Hepatol 2005; 43:1013-20; PMID:16168521; http://dx.doi.org/10.1016/j.jhep.2005.05.026
13. V.Groh, J.Wu, C.Yee, T.Spies. Tumour-derived soluble MIC ligands impari expression of NKG2D and T-cell activation. Nature 2002; 419:734-8; PMID:12384702; http://dx.doi.org/10.1038/nature01112
14. E.Cariani, M.Pilli, A.Zerbini, C.Rota, A.Olivani, P.Zanelli, A.Zanetti, T.Trenti, C.Ferrari, G.Missale. HLA and killer immunoglobulin-like receptor genes as outcome predictors of hepatitis C virus-related hepatocellular carcinoma. Clin Cancer Res 2013; 19:5465-73; PMID:23938290; http://dx.doi.org/10.1158/1078-0432.CCR-13-0986
15. B.Saha, G.Szabo. Innate immune cell networking in hepatitis C virus infection. J Leukoc Biol 2014; 96:757-66; PMID:25001860; http://dx.doi.org/10.1189/jlb.4MR0314-141R
16. J.M.Llovet, C.Brú, J.Bruix. Prognosis of hepatocellular carcinoma:the BCLC staging classification. Semin Liver Dis 1999; 19:329-38; PMID:10518312; http://dx.doi.org/10.1055/s-2007-1007122
17. R.Solana, C.Campos, A.Pera, R.Tarazona. Shaping of NK-cell subsets by aging. Curr Opin Immunol 2014; 29:56-61; PMID:24792889; http://dx.doi.org/10.1016/j.coi.2014.04.002
18. C.Campos, A.Pera, B.Sanchez-Correa, C.Alonso, I.Lopez-Fernandez, S.Morgado, R.Tarazona, R.Solana. Effect of age and CMV on NK-cell subpopulations. Exp Gerontol 2014; 54:130-7; PMID:24440462; http://dx.doi.org/10.1016/j.exger.2014.01.008
19. M.Baniyash. TCR zeta-chain downregulation:curtailing an excessive inflammatory immune response. Nat Rev Immunol 2004; 4:675-87; PMID:15343367; http://dx.doi.org/10.1038/nri1434
20. T.L.Whiteside. Down-regulation of zeta-chain expression in T cells:a biomarker of prognosis in cancer? Cancer Immunol Immunother 2004; 53:865-78; PMID:15118842; http://dx.doi.org/10.1007/s00262-004-0521-0
21. C.Bossard, S.Bézieau, T.Matysiak-Budnik, C.Volteau, C.L.Laboisse, F.Jotereau, J.F.Mosnier. HLA-E/β2 microglobulin overexpression in colorectal cancer is associated with recruitment of inhibitory immune cells and tumor progression. Int J Cancer 2012; 131:855-63; PMID:21953582; http://dx.doi.org/10.1002/ijc.26453
22. P.F.Cheung, C.W.Yip, N.C.Wong, D.Y.Fong, L.W.Ng, A.M.Wan, C.K.Wong, T.T.Cheung, I.O.Ng, R.T.Poon et al. Granulin-epithelin precursor renders hepatocellular carcinoma cells resistant to natural killer cytotoxicity. Cancer Immunol Res 2014; 2:1209-19; PMID:25315249; http://dx.doi.org/10.1158/2326-6066.CIR-14-0096
23. H.El Costa, A.Casemayou, M.Aguerre-Girr, M.Rabot, A.Berrebi, O.Parant, M.Clouet-Delannoy, L.Lombardelli, N.Jabrane-Ferrat, D.Rukavina et al. Critical and differential roles of NKp46- and NKp30-activating receptors expressed by uterine NK-cells in early pregnancy. J Immunol 2008; 181:3009-17; PMID:18713971; http://dx.doi.org/10.4049/jimmunol.181.5.3009
24. M.Elboim, R.Gazit, C.Gur, H.Ghadially, G.Betser-Cohen, O.Mandelboim. Tumor immunoediting by NKp46. J Immunol 2010; 184:5637-44; PMID:20404273; http://dx.doi.org/10.4049/jimmunol.0901644