Clinical Pattern of Early-Onset Inflammatory Bowel Disease in Saudi Arabia: A Multicenter National Study

Inflammatory Bowel Diseases

Volumn 22, Issue 8, 2016, Pages 1961-1970

  Al Hussaini, Abdulrahman ^a   El Mouzan, Mohammad ^b   Hasosah, Mohammed ^a   Al Mehaidib, Ali ^c   Alsaleem, Khalid ^c   Saadah, Omar I ^d   Al Edreesi, Mohammed ^e  

^a KING SAUD BIN ABDULAZIZ UNIVERSITY FOR HEALTH SCIENCES   (Saudi Arabia)

^b KING SAUD UNIVERSITY   (Saudi Arabia)

^c KING FAISAL SPECIALIST HOSPITAL AND RESEARCH CENTER   (Saudi Arabia)

^d KING ABDULAZIZ UNIVERSITY   (Saudi Arabia)

^e DHAHRAN HEALTH CENTER   (Saudi Arabia)

Author keywords

Crohn's disease; early onset inflammatory bowel disease; inflammatory bowel disease; Saudi Arabia; ulcerative colitis

Indexed keywords

6 MERCAPTOPURINE DERIVATIVE; ADALIMUMAB; INFLIXIMAB; MESALAZINE; STEROID;

ADOLESCENT; ARTICLE; CHILD; CLINICAL EVALUATION; COLITIS; COLON DISEASE; COLON SURGERY; CONSANGUINITY; CONTROLLED STUDY; CROHN DISEASE; DISEASE CLASSIFICATION; EARLY ONSET INFLAMMATORY BOWEL DISEASE; FAMILY HISTORY; FEMALE; GEOGRAPHIC DISTRIBUTION; GROUPS BY AGE; HUMAN; INFANT; INFLAMMATORY BOWEL DISEASE; MAJOR CLINICAL STUDY; MALE; MULTICENTER STUDY; ONSET AGE; PANCOLITIS; PRESCHOOL CHILD; PRIORITY JOURNAL; PROCTITIS; SAUDI ARABIA; SCHOOL CHILD; STEROID THERAPY; TODDLER; ULCERATIVE COLITIS; ABDOMINAL PAIN; CHILD DEVELOPMENT; CLINICAL TRIAL; COLON; COMPLICATION; DEVELOPMENTAL DISORDER; DIARRHEA; GENETICS; ILEUM; NEWBORN; PATHOLOGY; PHENOTYPE; RETROSPECTIVE STUDY; SEX FACTOR;

ABDOMINAL PAIN; ADOLESCENT; AGE OF ONSET; CHILD; CHILD DEVELOPMENT; CHILD, PRESCHOOL; COLITIS, ULCERATIVE; COLON; CONSANGUINITY; CROHN DISEASE; DEVELOPMENTAL DISABILITIES; DIARRHEA; FEMALE; HUMANS; ILEUM; INFANT; INFANT, NEWBORN; MALE; PHENOTYPE; RETROSPECTIVE STUDIES; SAUDI ARABIA; SEX FACTORS;

EID: 84979939212     PISSN: 10780998     EISSN: 15364844     Source Type: Journal    
DOI: 10.1097/MIB.0000000000000796     Document Type: Article

References (24)

1. Aloi M, Lionetti P, Barabino A, et al. Phenotype and disease course of early-onset pediatric inflammatory bowel disease. Inflamm Bowel Dis. 2014;20:597-605
2. Aloi M, D'Arcangelo G, Pofi F, et al. Presenting features and disease course of pediatric ulcerative colitis. J Crohn's Colitis. 2013;7:e509-e515
3. Gupta N, Bostrom AG, Kirschner BS, et al. Presentation and disease course in early-compared to later-onset pediatric Crohn's disease. Am J Gastroenterol. 2008;103:2092-2098
4. Paul T, Birnbaum A, Pal DK, et al. Distinct phenotype of early childhood inflammatory bowel disease. J Clin Gastroenterol. 2006;40:583-586
5. Heyman MB, Kirschner BS, Gold BD, et al. Children with early-onset inflammatory bowel disease (IBD): analysis of a pediatric IBD consortium registry. J Pediatr. 2005;146:35-40
6. Sawczenko A, Sandhu B. Presenting features of inflammatory bowel disease in Great Britain and Ireland. Arch Dis Child. 2003;88: 995-1000
7. Mamula P, Telega GW, Markowitz JE, et al. Inflammatory bowel disease in children 5 years of age and younger. Am J Gastroenterol. 2002;97: 2005-2010
8. Al-Qabandi WA, Buhamrah EK, Harandi KA, et al. Inflammatory bowel disease in children, an evolving problem in Kuwait. Saudi J Gastroenterol. 2011;17:323-327
9. Ahmaida AI, Al-Shaikhi SA. Childhood inflammatory bowel disease in Libya: epidemiological and clinical features. Libyan J Med. 2009;4: 70-74
10. Fallahi GH, Moazzami K, Tabatabaeiyan M, et al. Clinical characteristics of Iranian pediatric patients with inflammatory bowel disease. Acta Gastroenterol Belg. 2009;72:230-234
11. Saadah O. Ulcerative colitis in children and adolescents from the western region of Saudi Arabia. Saudi Med J. 2011;32:943-947
12. Saadah OI. Childhood onset Crohn's disease; experience from a university teaching hospital in Saudi Arabia. Ann Saudi Med. 2012;32: 596-602
13. El Mouzan MI, Al Mofarreh MA, Assiri AM, et al. Presenting features of childhood-onset inflammatory bowel disease in the central region of Saudi Arabia. Saudi Med J. 2012;33:423-428
14. Hasosah MY, Sukkar GA, Alsahafi AF, et al. Pediatric inflammatory bowel disease in the western region of Saudi Arabia. A retrospective analysis. Saudi Med J. 2013;34:651-653
15. IBD Working Group of the European Society for Pediatric Gastroenterology Hepatology and Nutrition. Inflammatory bowel disease in children and adolescents: recommendations for diagnosis\-The Porto criteria. J Pediatr Gastroenterol Nutr. 2005;41:1-7
16. Levine A, Griffiths A, Markowitz J, et al. Pediatric modification of the Montreal classification for inflammatory bowel disease: the Paris classification. Inflamm Bowel Dis. 2011;17:1314-1321
17. Uhlig H, Schwerd T, Koletzko S, et al. The diagnostic approach to monogenic very early onset inflammatory bowel disease. Gastroenterology. 2014;147:990-1007
18. Ledder O, Catto-Smith AG, Oliver MR, et al. Clinical patterns and outcome of early-onset inflammatory bowel disease. J Pediatr Gastroenterol Nutr. 2014;59:562-564
19. El-Hazmi M, Al-Swailem AR, Warsy AS, et al. Consanguinity among the Saudi Arabian population. J Med Genet. 1995;32:623-626
20. El Mouzan M, Al-Mofarreh M, Assiri A, et al. Consanguinity and Inflammatory Bowel Diseases: Is There a Relation? J Pediatr Gastroenterol Nutr. 2013;56:182-185
21. Benchimol EI, Fortinsky KJ, Gozdyra P, et al. Epidemiology of pediatric inflammatory bowel disease: a systematic review of international trends. Inflamm Bowel Dis. 2011;17:423-439
22. El Mouzan MI, Saadah O, Al-Saleem K, et al. Incidence of pediatric inflammatory bowel disease in Saudi Arabia: a multicenter national study. Inflamm Bowel Dis. 2014;20:1085-1090
23. Van Limbergen J, Russell RK, Drummond HE, et al. Definition of phenotypic characteristics of childhood-onset inflammatory bowel disease. Gastroenterology. 2008;135:1114-1122
24. Benchimol EI, Mack DR, Nguyen GC, et al. Outcomes, and health services burden of very early onset inflammatory bowel disease. Gastroenterology. 2014;147:803-813