Consanguinity and inflammatory bowel diseases: Is there a relation?

Journal of Pediatric Gastroenterology and Nutrition

Volumn 56, Issue 2, 2013, Pages 182-185

  Mouzan, Mohammad El ^a   Al Mofarreh, Mohammad ^b   Assiri, Asaad ^a   Hamid, Yassin ^a   Saeed, Anjum ^a  

^a KING KHALID UNIVERSITY HOSPITAL   (Saudi Arabia)

^b Division of Gastroenterology   (Saudi Arabia)

Author keywords

consanguinity; Crohn disease; ulcerative colitis

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; CHILD; CONSANGUINITY; CONTROLLED STUDY; CROHN DISEASE; ENTERITIS; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; PRESCHOOL CHILD; PREVALENCE; PRIORITY JOURNAL; SCHOOL CHILD; ULCERATIVE COLITIS;

ADOLESCENT; ADULT; CHILD; CHILD, PRESCHOOL; COLITIS, ULCERATIVE; CONSANGUINITY; CROHN DISEASE; FAMILY; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INFANT; MALE; PREVALENCE; YOUNG ADULT;

EID: 84873057636     PISSN: 02772116     EISSN: 15364801     Source Type: Journal    
DOI: 10.1097/MPG.0b013e31826d9987     Document Type: Article

References (30)

1. Loftus EV. Clinical epidemiology of inflammatory bowel disease: Incidence, prevalence, and environmental influences. Gastroenterology 2004;126:1504-17
2. Kugathasan S, Judd RH, Hoffmann RG, et al. Epidemiologic and clinical characteristics of children with newly diagnosed inflammatory bowel disease in Wisconsin: A statewide population-based study. J Pediatr 2003;143:525-31
3. Farrokhyar F, Swarbrick ET, Irvine EJ. A critical review of epidemiological studies in inflammatory bowel disease. Scan J Gastroenterology 2001;36:2-15
4. Yang SK, Loftus EV Jr, Sandborn WJ. Epidemiology of inflammatory bowel disease in Asia. Inflamm Bowel Dis 2001;7:260-70
5. Benchimol EI, Fortinsky KJ, Gozdyra P, et al. Epidemiology of pediatric inflammatory bowel disease: A systematic review of international trends. Inflamm Bowel Dis 2011;17:423-39
6. Bittles AH. Consanguinity and its relevance to clinical genetics. Clin Genet 2001;60:89-98
7. Al-Gazali L, Hammami H, Al Arrayad S. Genetic disorders in the Arab world. Br Med J 2006;333:831-4
8. Bener A, Hussain R. Consanguineous unions and child health in the State of Qatar. Paediatr Perinat Epidemiol 2006;20:372-8
9. El Mouzan MI, Al Salloum AA, Al Herbish AS, et al. Consanguinity and major genetic disorders in Saudi children; a community-based cross-sectional study. Ann Saudi Med 2008;28:169-73
10. El Mouzan MI, Al Salloum AA, Al Herbish AS, et al. Does consanguinity increase the risk of bronchial asthma in children? Ann Thoracic Med 2008;3:41-3
11. Abdulrazzaq YM, Bener A, Al-Gazali LI, et al. A study of possible deleterious effects of consanguinity. Clin Gen 1997;51:167-73
12. Lees CW, Barrett JC, Barkes M, et al. New IBD genetics. Gut 2011;60:1739-53
13. Ouda S, Saadah O, El Meligy O, et al. Genetic and dental study of patients with celiac disease. J Clin Pediatr Dent 2010;35:217-24
14. Escher JC, Amil Dias J, Bochenek K, et al. Inflammatory bowel disease in children and adolescents: Recommendations for diagnosis - The Porto Criteria. IBD Working Group of the European Society for Paediatric Gastroenterology, Hepatology and Nutrition (ESPGHAN). J Pediatr Gastroenterol Nutr 2005;41:1-7
15. Bousvaros A, Antonioli DA, Colletti RB, et al. Differentiating ulcerative colitis from crohn disease in children and young adults: Report of a Working Group of the North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition and the Crohn's and Colitis Foundation of America. J Pediatr Gastroenterol Nutr 2007;44:653-74
16. El Mouzan MI, Al-Salloum AA, Al-Herbish AS, et al. Regional variations of consanguinity in Saudi Arabia. Saudi med J 2007; 28:1881-4
17. Levine A, Griffiths A, Markovitz J, et al. Pediatric modification of the Montrial classification for inflammatory bowel disease: The Paris classification. Inflamm Bowel Dis 2011;17:1314-21
18. El Mouzan MI, Al Mofarreh MA, Assiri AM, et al. Presenting features of childhood-onset inflammatory bowel disease in the central region of of Saudi Arabia. Saudi Med J 2012;33:423-8
19. El Mouzan MI, Abdullah AM, Al Habbal MT. Epidemiology of juvenile-onset inflammatory bowel disease in Central Saudi Arabia. J Trop Pediatr 2006;52:69-71
20. Ahmaida A, Al Shaikhi S. Childhood IBD in Libya: Epidemiological and clinical features. Libyan J Med 2009;4:70-4
21. Abdul-Baki H, ElHajj I, El-Zahabi LMN, et al. Clinical epidemiology of inflammatory bowel disease in Lebanon. Inflamm Bowel Dis 2007; 13:475-80
22. El-Hazmi MA, Al-Swailem AR,Warsy AS, et al. Consanguinity among the Saudi Arabian population. J Med Genet 1995;32:623-6
23. Isbister WH, Hubler M. Inflammatory bowel disease in Saudi Arabia: Presentation and initial management. J Gastroenterol Hepatol 1998; 13:1119-24
24. Al-Mofarreh MA, Al Mofleh IA, Al-Teimi IN, et al. Crohn's disease in a Saudi outpatient population: Is it still rare. Saudi J Gastroenterol 2009;15:111-6
25. Polito JM 2nd, Childs B, Mellits ED, et al. Crohn's disease: Influence of age at diagnosis on site and clinical type of disease. Gastroenterology 1996;111:580-6
26. Griffiths AM. Specificities of inflammatory bowel disease in childhood. Best Pract Res Clin Gastroenterol 2004;18:509-23
27. Chattani HK, Nigam SB, Sama SK, et al. Ulcerative colitis in the tropics. Br Med J 1967;4:204-7
28. Kitahora T, Utsunomiya T, Yokota A. Epidemiological study of ulcerative colitis in Japan: Incidence and familial occurrence. The Epidemiology Group of the Research Committee of Inflammatory Bowel Disease in Japan. J Gastroenterol 1995;30(suppl 8):5-8
29. Park JP, Yang SK, Byeon JK, et al. Familial occurrence of inflammatory bowel disease in Korea. Inflamm Bowel Dis 2006;12:1146-51
30. Lewis R. Human Genetics: Concepts and Application. New York: McGraw Hill; 2005