The Wnt-target gene Dlk-1 is regulated by the Prmt5-associated factor Copr5 during adipogenic conversion

Biology Open

Volumn 4, Issue 3, 2015, Pages 312-316

  Paul, Conception ^a,b   Sardet, Claude ^a,b,c   Fabbrizio, Eric ^a,b,c  

^a CNRS   (France)

^b UNIV MONTPELLIER   (France)

^c INSTITUT DE RECHERCHE EN CANCÉROLOGIE DE MONTPELLIER   (France)

Author keywords

Adipocyte; Copr5; Differentiation; Dlk 1; Prmt5; catenin

Indexed keywords

BETA CATENIN; COPR5 PROTEIN; DLK 1 PROTEIN; PROTEIN ARGININE METHYLTRANSFERASE; REGULATOR PROTEIN; UNCLASSIFIED DRUG; WNT PROTEIN;

ADIPOCYTE; ADIPOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL FATE; CELL FRACTIONATION; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; EMBRYOID BODY; FIBROBLAST; GENE EXPRESSION; GENE TARGETING; MOUSE; NONHUMAN; PROMOTER REGION; RECEPTOR UPREGULATION; RETROPERITONEAL FAT; STEM CELL; STROMA CELL; TRANSCRIPTION REGULATION; TRANSCRIPTOMICS; VASCULAR STROMAL FRACTION; WHITE ADIPOSE TISSUE; WNT SIGNALING PATHWAY;

EID: 84979788851     PISSN: None     EISSN: 20466390     Source Type: Journal    
DOI: 10.1242/bio.201411247     Document Type: Article

References (23)

1. Birsoy, K., Berry, R., Wang, T., Ceyhan, O., Tavazoie, S., Friedman, J. M. and Rodeheffer, M. S. (2011). Analysis of gene networks in white adipose tissue development reveals a role for ETS2 in adipogenesis. Development 138, 4709-4719.
2. Blauwkamp, T. A., Chang, M. V. and Cadigan, K. M. (2008). Novel TCF-binding sites specify transcriptional repression by Wnt signalling. EMBO J. 27, 1436-1446.
3. Chen, Z., Torrens, J. I., Anand, A., Spiegelman, B. M. and Friedman, J. M. (2005). Krox20 stimulates adipogenesis via C/EBPbeta-dependent and -independent mechanisms. Cell Metab. 1, 93-106.
4. Curtis, C. D. and Griffin, C. T. (2012). The chromatin-remodeling enzymes BRG1 and CHD4 antagonistically regulate vascular Wnt signaling. Mol. Cell. Biol. 32, 1312-1320.
5. Dacwag, C. S., Bedford, M. T., Sif, S. and Imbalzano, A. N. (2009). Distinct protein arginine methyltransferases promote ATP-dependent chromatin remodeling function at different stages of skeletal muscle differentiation. Mol. Cell. Biol. 29, 1909-1921.
6. Dani, C., Smith, A. G., Dessolin, S., Leroy, P., Staccini, L., Villageois, P., Darimont, C. and Ailhaud, G. (1997). Differentiation of embryonic stem cells into adipocytes in vitro. J. Cell Sci. 110, 1279-1285.
7. de la Serna, I. L., Carlson, K. A. and Imbalzano, A. N. (2001). Mammalian SWI/ SNF complexes promote MyoD-mediated muscle differentiation. Nat. Genet. 27, 187-190.
8. Griffin, C. T., Curtis, C. D., Davis, R. B., Muthukumar, V. and Magnuson, T. (2011). The chromatin-remodeling enzyme BRG1 modulates vascular Wnt signaling at two levels. Proc. Natl. Acad. Sci. USA 108, 2282-2287.
9. Huang, J., Vogel, G., Yu, Z., Almazan, G. and Richard, S. (2011). Type II arginine methyltransferase PRMT5 regulates gene expression of inhibitors of differentiation/DNA binding Id2 and Id4 during glial cell differentiation. J. Biol. Chem. 286, 44424-44432.
10. Lacroix, M., El Messaoudi, S., Rodier, G., Le Cam, A., Sardet, C. and Fabbrizio, E. (2008). The histone-binding protein COPR5 is required for nuclear functions of the protein arginine methyltransferase PRMT5. EMBO Rep. 9, 452-458.
11. LeBlanc, S. E., Konda, S., Wu, Q., Hu, Y. J., Oslowski, C. M., Sif, S. and Imbalzano, A. N. (2012). Protein arginine methyltransferase 5 (Prmt5) promotes gene expression of peroxisome proliferator-activated receptor c2 (PPARc2) and its target genes during adipogenesis. Mol. Endocrinol. 26, 583-597.
12. Lee, K., Villena, J. A., Moon, Y. S., Kim, K. H., Lee, S., Kang, C. and Sul, H. S. (2003). Inhibition of adipogenesis and development of glucose intolerance by soluble preadipocyte factor-1 (Pref-1). J. Clin. Invest. 111, 453-461.
13. MacDougald, O. A. and Lane, M. D. (1995). Transcriptional regulation of gene expression during adipocyte differentiation. Annu. Rev. Biochem. 64, 345-373.
14. Moon, Y. S., Smas, C. M., Lee, K., Villena, J. A., Kim, K. H., Yun, E. J. and Sul, H. S. (2002). Mice lacking paternally expressed Pref-1/Dlk1 display growth retardation and accelerated adiposity. Mol. Cell. Biol. 22, 5585-5592.
15. Mortensen, S. B., Jensen, C. H., Schneider, M., Thomassen, M., Kruse, T. A., Laborda, J., Sheikh, S. P. and Andersen, D. C. (2012). Membrane-tethered delta-like 1 homolog (DLK1) restricts adipose tissue size by inhibiting preadipocyte proliferation. Diabetes 61, 2814-2822.
16. Paul, C., Sardet, C. and Fabbrizio, E. (2012). The histone- and PRMT5-associated protein COPR5 is required for myogenic differentiation. Cell Death Differ. 19, 900-908.
17. Rosen, E. D. and MacDougald, O. A. (2006). Adipocyte differentiation from the inside out. Nat. Rev. Mol. Cell Biol. 7, 885-896.
18. Smas, C. M. and Sul, H. S. (1993). Pref-1, a protein containing EGF-like repeats, inhibits adipocyte differentiation. Cell 73, 725-734.
19. Tang, Q. Q. and Lane, M. D. (2012). Adipogenesis: from stem cell to adipocyte. Annu. Rev. Biochem. 81, 715-736.
20. Tee, W. W., Pardo, M., Theunissen, T. W., Yu, L., Choudhary, J. S., Hajkova, P. and Surani, M. A. (2010). Prmt5 is essential for early mouse development and acts in the cytoplasm to maintain ES cell pluripotency. Genes Dev. 24, 2772-2777.
21. Tontonoz, P. and Spiegelman, B. M. (2008). Fat and beyond: the diverse biology of PPARgamma. Annu. Rev. Biochem. 77, 289-312.
22. Weng, T., Gao, L., Bhaskaran, M., Guo, Y., Gou, D., Narayanaperumal, J., Chintagari, N. R., Zhang, K. and Liu, L. (2009). Pleiotrophin regulates lung epithelial cell proliferation and differentiation during fetal lung development via beta-catenin and Dlk1. J. Biol. Chem. 284, 28021-28032.
23. Zeve, D., Tang, W. and Graff, J. (2009). Fighting fat with fat: the expanding field of adipose stem cells. Cell Stem Cell 5, 472-481.