Neuropathic pain: An updated grading system for research and clinical practice

Pain

Volumn 157, Issue 8, 2016, Pages 1599-1606

  Finnerup, Nanna B ^a   Haroutounian, Simon ^b   Kamerman, Peter ^c   Baron, Ralf ^d   Bennett, David L H ^e   Bouhassira, Didier ^f,g   Cruccu, Giorgio ^h   Freeman, Roy ⁱ   Hansson, Per ^j,k   Nurmikko, Turo ^l   Raja, Srinivasa N ^m   Rice, Andrew S C ^n,o   Serra, Jordi ^p   Smith, Blair H ^q   Treede, Rolf Detlef ^r   Jensen, Troels S ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF THE WITWATERSRAND   (South Africa)

^d UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^e UNIVERSITY OF OXFORD   (United Kingdom)

^f HÔPITAL AMBROISE PARÉ   (France)

^g LABORATOIRE DES SCIENCES DU CLIMAT ET DE L ENVIRONNEMENT   (France)

^h SAPIENZA UNIVERSITY OF ROME   (Italy)

ⁱ HARVARD MEDICAL SCHOOL   (United States)

^j OSLO UNIVERSITY HOSPITAL   (Norway)

^k KAROLINSKA INSTITUTE   (Sweden)

^l THE WALTON CENTRE NHS FOUNDATION TRUST   (United Kingdom)

^m JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

ⁿ IMPERIAL COLLEGE LONDON   (United Kingdom)

^o CHELSEA AND WESTMINSTER HOSPITAL NHS FOUNDATION TRUST   (United Kingdom)

^p Neuroscience Technologies   (Spain)

^q UNIVERSITY OF DUNDEE   (United Kingdom)

^r UNIVERSITY OF HEIDELBERG   (Germany)

more..

Author keywords

Definite; Definition; Grading; Neuropathic pain; Possible; Probable

Indexed keywords

ARTICLE; CITATION ANALYSIS; CLINICAL PRACTICE; CLINICAL RESEARCH; HUMAN; NEUROPATHIC PAIN; PRIORITY JOURNAL; ANALGESIA; NEURALGIA; PAIN MEASUREMENT; PATHOPHYSIOLOGY; QUESTIONNAIRE; RESEARCH; STANDARDS;

HUMANS; NEURALGIA; PAIN MANAGEMENT; PAIN MEASUREMENT; RESEARCH; SURVEYS AND QUESTIONNAIRES;

EID: 84979716007     PISSN: 03043959     EISSN: 18726623     Source Type: Journal    
DOI: 10.1097/j.pain.0000000000000492     Document Type: Article

References (35)

1. Bennett DL, Woods CG. Painful and painless channelopathies. Lancet Neurol 2014;13:587-99
2. Bennett M. The LANSS Pain Scale: the Leeds assessment of neuropathic symptoms and signs. PAIN 2001;92:147-57
3. Bennett MI, Attal N, Backonja MM, Baron R, Bouhassira D, Freynhagen R, Scholz J, Tolle TR, Wittchen HU, Jensen TS. Using screening tools to identify neuropathic pain. PAIN 2007;127:199-203
4. Bennett MI, Rayment C, Hjermstad M, Aass N, Caraceni A, Kaasa S. Prevalence and aetiology of neuropathic pain in cancer patients a systematic review. PAIN 2012;153:359-65
5. Birklein F, O'Neill D, Schlereth T. Complex regional pain syndrome: An optimistic perspective. Neurology 2015;84:89-96
6. Bouhassira D, Attal N, Alchaar H, Boureau F, Brochet B, Bruxelle J, Cunin G, Fermanian J, Ginies P, Grun-Overdyking A, Jafari-Schluep H, Lanteri-Minet M, Laurent B, Mick G, Serrie A, Valade D, Vicaut E. Comparison of pain syndromes associated with nervous or somatic lesions and development of a new neuropathic pain diagnostic questionnaire (DN4). PAIN 2005;114:29-36
7. Caty G, Hu L, Legrain V, Plaghki L, Mouraux A. Psychophysical and electrophysiological evidence for nociceptive dysfunction in complex regional pain syndrome. PAIN 2013;154:2521-8
8. Ceyhan GO, Demir IE, Maak M, Friess H. Fate of nerves in chronic pancreatitis: Neural remodeling and pancreatic neuropathy. Best Pract Res Clin Gastroenterol 2010;24:311-22
9. Doppler K, Rittner HL, Deckart M, Sommer C. Reduced dermal nerve fiber diameter in skin biopsies of patients with fibromyalgia. PAIN 2015; 156:2319-25
10. Finnerup NB, Attal N, Haroutounian S, McNicol E, Baron R, Dworkin RH, Gilron I, Haanpaa M, Hansson P, Jensen TS, Kamerman PR, Lund K, Moore A, Raja SN, Rice AS, Rowbotham M, Sena E, Siddall P, Smith BH, Wallace M. Pharmacotherapy for neuropathic pain in adults a systematic review and meta-analysis. Lancet Neurol 2015;14:162-73
11. Freynhagen R, Baron R, Gockel U, Tölle TR. painDETECT a new screening questionnaire to identify neuropathic components in patients with back pain. Curr Med Res Opin 2006;22:1911-20
12. Geber C,MagerlW, Fondel R, Fechir M, Rolke R, Vogt T, Treede RD, Birklein F. Numbness in clinical and experimental pain-A cross-sectional study exploring the mechanisms of reduced tactile function. PAIN2008;139:73-81
13. Haanpaa M, Attal N, Backonja M, Baron R, Bennett M, Bouhassira D, Cruccu G, Hansson P, Haythornthwaite JA, Iannetti GD, Jensen TS, Kauppila T, Nurmikko TJ, Rice AS, Rowbotham M, Serra J, Sommer C, Smith BH, Treede RD. NeuPSIG guidelines on neuropathic pain assessment. PAIN 2011;152:14-27
14. Hoimyr H, Rokkones KA, von Sperling ML, Finnerup K, Jensen TS, Finnerup NB. Persistent pain after lymph node excision in patients with malignant melanoma is neuropathic. PAIN 2011;152:2721-8
15. IASP. Global year against neuropathic pain. 2015; Available at: http:// www.iasp-pain.org/GlobalYear/NeuropathicPain?navItemNumber5580. Accessed September 24, 2015
16. IASP. ISAP taxonomy. 2012; Available at: http://www.iasp-pain.org/ Education/Content.aspx?ItemNumber51698andnavItemNumber5576. Accessed September 24, 2015
17. Jensen TS, Baron R, Haanpaa M, Kalso E, Loeser JD, Rice AS, Treede RD. A new definition of neuropathic pain. PAIN 2011;152:2204-5
18. Krause SJ, Backonja MM. Development of a neuropathic pain questionnaire. Clin J Pain 2003;19:306-14
19. Leffler AS, Hansson P, Kosek E. Somatosensory perception in patients suffering from long-term trapeziusmyalgia at the site overlying themost painful part of the muscle and in an area of pain referral. Eur J Pain 2003;7:267-76
20. MaierC,BaronR, Tolle TR,Binder A,Birbaumer N, Birklein F, Gierthmuhlen J, Flor H, Geber C, Huge V, Krumova EK, Landwehrmeyer GB, Magerl W, Maihofner C, Richter H, Rolke R, Scherens A, Schwarz A, Sommer C, Tronnier V, Uceyler N, Valet M, Wasner G, Treede RD. Quantitative sensory testing in the German Research Network on Neuropathic Pain (DFNS): somatosensory abnormalities in 1236 patients with different neuropathic pain syndromes. PAIN 2010;150:439-50
21. Marchettini P, Marangoni C, Lacerenza M, Formaglio F. The Lindblom roller. Eur J Pain 2003;7:359-64
22. Mick G, Baron R, Correa-Illanes G, Hans G, Mayoral V, Frias X, Sintes D, Keller T. Is an easy and reliable diagnosis of localized neuropathic pain (LNP) possible in general practice? Development of a screening tool based on IASP criteria. Curr Med Res Opin 2014;30:1357-66
23. Oaklander AL, Fields HL. Is reflex sympathetic dystrophy/complex regional pain syndrome type I a small-fiber neuropathy? Ann Neurol 2009;65:629-38
24. Portenoy R. Development and testing of a neuropathic pain screening questionnaire: ID Pain. Curr Med Res Opin 2006;22:1555-65
25. Schuh-Hofer S, Wodarski R, Pfau DB, Caspani O, Magerl W, Kennedy JD, Treede RD. One night of total sleep deprivation promotes a state of generalized hyperalgesia a surrogate pain model to study the relationship of insomnia and pain. PAIN 2013;154:1613-21
26. Serra J, Collado A, Sola R, Antonelli F, Torres X, Salgueiro M, Quiles C, Bostock H. Hyperexcitable C nociceptors in fibromyalgia. Ann Neurol 2014;75:196-208
27. Sorensen BS, Jorgensen J, Jensen TS, Finnerup NB. Pain following blood donation a questionnaire study of long-term morbidity (LTM) in blood donors. Vox Sang 2015;109:18-24
28. Thakur M, Dickenson AH, Baron R. Osteoarthritis pain: nociceptive or neuropathic? Nat Rev Rheumatol 2014;10:374-80
29. Torrance N, Ferguson JA, Afolabi E, Bennett MI, Serpell MG, Dunn KM, Smith BH. Neuropathic pain in the community: more under-treated than refractory? PAIN 2013;154:690-9
30. Treede RD, Jensen TS, Campbell JN, Cruccu G, Dostrovsky JO, Griffin JW, Hansson P, Hughes R, Nurmikko T, Serra J. Neuropathic pain: redefinition and a grading system for clinical and research purposes. Neurology 2008;70:1630-5
31. Treede RD, Rief W, Barke A, Aziz Q, Bennett MI, Benoliel R, Cohen M, Evers S, Finnerup NB, First MB, Giamberardino MA, Kaasa S, Kosek E, Lavand'homme P, Nicholas M, Perrot S, Scholz J, Schug S, Smith BH, Svensson P, Vlaeyen JW, Wang SJ. A classification of chronic pain for ICD-11. PAIN 2015;156:1003-7
32. Vaegter HB, Andersen PG, Madsen MF, Handberg G, Enggaard TP. Prevalence of neuropathic pain according to the IASP grading system in patients with chronic non-malignant pain. Pain Med 2014;15: 120-7
33. Waxman SG, Merkies IS, Gerrits MM, Dib-Hajj SD, Lauria G, Cox JJ, Wood JN, Woods CG, Drenth JP, Faber CG. Sodium channel genes in pain-related disorders: phenotype-genotype associations and recommendations for clinical use. Lancet Neurol 2014;13:1152-60
34. Wiech K, Tracey I. The influence of negative emotions on pain: behavioral effects and neural mechanisms. Neuroimage 2009;47:987-94
35. Woolf CJ. Central sensitization: implications for the diagnosis and treatment of pain. PAIN 2011;152:S2-15