Consistently inconsistent - Bone marrow mononuclear stem cell therapy following acute myocardial infarction

Circulation Research

Volumn 119, Issue 3, 2016, Pages 404-406

  Henry, Timothy D ^a   Moyé, Lem ^b   Traverse, Jay H ^c  

^a CEDARS SINAI MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SCHOOL OF PUBLIC HEALTH   (United States)

^c MINNEAPOLIS HEART INSTITUTE FOUNDATION   (United States)

Author keywords

bone marrow; Editorials; myocardial infarction; regenerative medicine; stem cell

Indexed keywords

ACUTE HEART INFARCTION; ARTICLE; BONE MARROW DERIVED MONONUCLEAR CELL; HEART INFARCTION SIZE; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE FUNCTION; HUMAN; META ANALYSIS (TOPIC); PERCUTANEOUS CORONARY INTERVENTION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; STEM CELL TRANSPLANTATION; BONE MARROW; BONE MARROW CELL; BONE MARROW TRANSPLANTATION; HEART INFARCTION;

BONE MARROW; BONE MARROW CELLS; BONE MARROW TRANSPLANTATION; HUMANS; MYOCARDIAL INFARCTION; STEM CELL TRANSPLANTATION;

EID: 84979545714     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.116.309231     Document Type: Article

References (15)

1. Schächinger V, Erbs S, Elsässer A, Haberbosch W, Hambrecht R, Hölschermann H, Yu J, Corti R, Mathey DG, Hamm CW, Süselbeck T, Assmus B, Tonn T, Dimmeler S, Zeiher AM, REPAIR-AMI Investigators Intracoronary bone marrow-derived progenitor cells in acute myocardial infarction. N Engl J Med 2006 355 1210 1221. doi: 10.1056/NEJMoa060186
2. Lunde K, Solheim S, Aakhus S, Intracoronary injection of mononuclear bone marrow cells in acute myocardial infarction. N Engl J Med 2006 355 1199 1209. doi: 10.1056/NEJMoa055706
3. Janssens S, Dubois C, Bogaert J, Autologous bone marrow-derived stem-cell transfer in patients with ST-segment elevation myocardial infarction: double-blind, randomised controlled trial. Lancet 2006 367 113 121. doi: 10.1016/S0140-6736(05)67861-0
4. Sürder D, Manka R, Moccetti T, Effect of bone marrow-derived mononuclear cell treatment, early or late after acute myocardial infarction: twelve months CMR and long-Term clinical results. Circ Res 2016 119 481 490. doi: 10.1161/CIRCRESAHA.116.308639
5. Sürder D, Manka R, Lo Cicero V, Intracoronary injection of bone marrow-derived mononuclear cells early or late after acute myocardial infarction: effects on global left ventricular function. Circulation 2013 127 1968 1979. doi: 10.1161/CIRCULATIONAHA.112.001035
6. Traverse JH, Henry TD, Pepine CJ, Cardiovascular Cell Therapy Research Network (CCTRN) Effect of the use and timing of bone marrow mononuclear cell delivery on left ventricular function after acute myocardial infarction: the TIME randomized trial. JAMA 2012 308 2380 2389. doi: 10.1001/jama.2012.28726
7. Traverse JH, Henry TD, Ellis SG, Cardiovascular Cell Therapy ResearchNetwork Effect of intracoronary delivery of autologous bone marrow mononuclear cells 2 to 3 weeks following acute myocardial infarction on left ventricular function: the LateTIME randomized trial. JAMA 2011 306 2110 2119. doi: 10.1001/jama.2011.1670
8. Delewi R, Hirsch A, Tijssen JG, Impact of intracoronary bone marrow cell therapy on left ventricular function in the setting of ST-segment elevation myocardial infarction: a collaborative meta-Analysis. Eur Heart J 2014 35 989 998. doi: 10.1093/eurheartj/eht372
9. de Jong R, Houtgraaf JH, Samiei S, Boersma E, Duckers HJ, Intracoronary stem cell infusion after acute myocardial infarction: a meta-Analysis and update on clinical trials. Circ Cardiovasc Interv 2014 7 156 167. doi: 10.1161/CIRCINTERVENTIONS.113.001009
10. Gyöngyösi M, Wojakowski W, Lemarchand P, ACCRUE Investigators Meta-Analysis of Cell-based CaRdiac stUdiEs (ACCRUE) in patients with acute myocardial infarction based on individual patient data. Circ Res 2015 116 1346 1360. doi: 10.1161/CIRCRESAHA.116.304346
11. Perin EC, Willerson JT, Pepine CJ, Cardiovascular Cell Therapy Research Network (CCTRN) Effect of transendocardial delivery of autologous bone marrow mononuclear cells on functional capacity, left ventricular function, and perfusion in chronic heart failure: the FOCUS-CCTRN trial. JAMA 2012 307 1717 1726. doi: 10.1001/jama.2012.418
12. Traverse JH, Henry TD, Pepine CJ, Willerson JT, Ellis SG, One-year follow-up of intracoronary stem cell delivery on left ventricular function following ST-elevation myocardial infarction. JAMA 2014 311 301 302. doi: 10.1001/jama.2013.282674
13. Traverse JH, Henry TD, Moye' LA, Is the measurement of left ventricular ejection fraction the proper end point for cell therapy trials? An analysis of the effect of bone marrow mononuclear stem cell administration on left ventricular ejection fraction after ST-segment elevation myocardial infarction when evaluated by cardiac magnetic resonance imaging. Am Heart J 2011 162 671 677. doi: 10.1016/j.ahj.2011.06.019
14. Simari RD, Pepine CJ, Traverse JH, Henry TD, Bolli R, Spoon DB, Yeh E, Hare JM, Schulman IH, Anderson RD, Lambert C, Sayre SL, Taylor DA, Ebert RF, Moye LA, Bone marrow mononuclear cell therapy for acute myocardial infarction: a perspective from the Cardiovascular Cell Therapy Reasearch Network (CCTRN). Circ Res 2014 114 1564 1568
15. The GUSTO Investigators An international randomized trial comparing four thrombolytic strategies for acute myocardial infarction. N Engl J Med 1993 329 673 682