Meta-analysis of cell-based CaRdiac stUdiEs (ACCRUE) in patients with acute myocardial infarction based on individual patient data

Circulation Research

Volumn 116, Issue 8, 2015, Pages 1346-1360

  Gyöngyösi, Mariann ^a   Wojakowski, Wojciech ^b   Lemarchand, Patricia ^c   Lunde, Ketil ^d   Tendera, Michal ^b   Bartunek, Jozef ^e   Marban, Eduardo ^f   Assmus, Birgit ^g   Henry, Timothy D ^f   Traverse, Jay H ^h   Moyé, Lemuel A ⁱ   Sürder, Daniel ^j,k   Corti, Roberto ^k,l   Huikuri, Heikki ^m   Miettinen, Johanna ^m   Wöhrle, Jochen ⁿ   Obradovic, Slobodan ^o   Roncalli, Jérome ^p   Malliaras, Konstantinos ^f   Pokushalov, Evgeny ^q   Romanov, Alexander ^q   Kastrup, Jens ^r   Bergmann, Martin W ^s   Atsma, Douwe E ^t   Diederichsen, Axel ^u   Edes, Istvan ^v   Benedek, Imre ^w   Benedek, Theodora ^w   Pejkov, Hristo ^x   Nyolczas, Noemi ^y   Pavo, Noemi ^a   Bergler Klein, Jutta ^a   Pavo, Imre J ^a   Sylven, Christer ^z   Berti, Sergio ^aa   Navarese, Eliano P ^ab,ac   Maurer, Gerald ^a   more..

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

^b MEDICAL UNIVERSITY OF SILESIA   (Poland)

^c L INSTITUT DU THORAX   (France)

^d OSLO UNIVERSITY HOSPITAL   (Norway)

^e OLV HOSPITAL   (Belgium)

^f CEDARS SINAI MEDICAL CENTER   (United States)

^g GOETHE UNIVERSITY   (Germany)

^h MINNEAPOLIS HEART INSTITUTE FOUNDATION   (United States)

ⁱ UNIVERSITY OF TEXAS SCHOOL OF PUBLIC HEALTH   (United States)

^j UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^k DIVISION OF CARDIOLOGY   (Switzerland)

^l KLINIK HIRSLANDEN   (Switzerland)

^m UNIVERSITY OF OULU   (Finland)

ⁿ UNIVERSITY OF ULM   (Germany)

^o UNIVERSITY OF DEFENCE   (Serbia)

^p TOULOUSE UNIVERSITY HOSPITAL   (France)

^q MESHALKIN NATIONAL MEDICAL RESEARCH CENTER   (Russian Federation)

^r UNIVERSITY OF COPENHAGEN   (Denmark)

^s DEPARTMENT OF CARDIOLOGY   (Germany)

^t LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^u ODENSE UNIVERSITY HOSPITAL   (Denmark)

^v UNIVERSITY OF DEBRECEN   (Hungary)

^w UNIVERSITY OF MEDICINE AND PHARMACY   (Romania)

^x University Cardiology Clinic   (Macedonia)

^y Medical Centre   (Hungary)

^z KAROLINSKA INSTITUTE   (Sweden)

^aa INSTITUTE OF CLINICAL PHYSIOLOGY   (Italy)

^ab HEINRICH HEINE UNIVERSITY   (Germany)

^ac 10th Military Research Hospital and Polyclinic   (Poland)

more..

Author keywords

anterior wall myocardial infarction; heart failure; meta analysis; outcome assessment; stem cells

Indexed keywords

ACUTE HEART INFARCTION; ARTICLE; CARDIAC PATIENT; CAUSE OF DEATH; CELL THERAPY; CEREBROVASCULAR ACCIDENT; HEART LEFT VENTRICLE EJECTION FRACTION; HEART LEFT VENTRICLE ENDDIASTOLIC VOLUME; HEART LEFT VENTRICLE ENDSYSTOLIC VOLUME; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE REVASCULARIZATION; HUMAN; META ANALYSIS; NUCLEAR MAGNETIC RESONANCE IMAGING; PATIENT SAFETY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); RECURRENCE RISK; TREATMENT OUTCOME; ADVERSE EFFECTS; AGED; BONE MARROW TRANSPLANTATION; CEREBROVASCULAR DISORDERS; CHI SQUARE DISTRIBUTION; CONVALESCENCE; DISEASE FREE SURVIVAL; FACTUAL DATABASE; FEMALE; HEART CONTRACTION; HEART MUSCLE; HEART STROKE VOLUME; HEART VENTRICLE REMODELING; KAPLAN MEIER METHOD; MALE; MIDDLE AGED; MORTALITY; MYOCARDIAL INFARCTION; PATHOLOGY; PATHOPHYSIOLOGY; PROPORTIONAL HAZARDS MODEL; PROSPECTIVE STUDY; RECURRENT DISEASE; REGENERATION; RISK FACTOR; TIME;

AGED; BONE MARROW TRANSPLANTATION; CEREBROVASCULAR DISORDERS; CHI-SQUARE DISTRIBUTION; DATABASES, FACTUAL; DISEASE-FREE SURVIVAL; FEMALE; HUMANS; KAPLAN-MEIER ESTIMATE; MALE; MIDDLE AGED; MYOCARDIAL CONTRACTION; MYOCARDIAL INFARCTION; MYOCARDIUM; PROPORTIONAL HAZARDS MODELS; PROSPECTIVE STUDIES; RANDOMIZED CONTROLLED TRIALS AS TOPIC; RECOVERY OF FUNCTION; RECURRENCE; REGENERATION; RISK FACTORS; STROKE VOLUME; TIME FACTORS; TREATMENT OUTCOME; VENTRICULAR FUNCTION, LEFT; VENTRICULAR REMODELING;

EID: 84929003354     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.116.304346     Document Type: Article

References (27)

1. Abdel-Latif A, Bolli R, Tleyjeh IM, Montori VM, Perin EC, Hornung CA, Zuba-Surma EK, Al-Mallah M, Dawn B., Adult bone marrow-derived cells for cardiac repair: a systematic review and meta-analysis. Arch Intern Med 2007; 167: 989-997. doi: 10.1001/archinte.167.10.989
2. Clifford DM, Fisher SA, Brunskill SJ, Doree C, Mathur A, Watt S, Martin-Rendon E., Stem cell treatment for acute myocardial infarction. Cochrane Database Syst Rev 2012 2 CD006536. doi: 10.1002/14651858.CD006536.pub3
3. Jeevanantham V, Butler M, Saad A, Abdel-Latif A, Zuba-Surma EK, Dawn B., Adult bone marrow cell therapy improves survival and induces long-term improvement in cardiac parameters: a systematic review and meta-analysis. Circulation 2012; 126: 551-568. doi: 10.1161/CIRCULATIONAHA.111.086074
4. de Jong R, Houtgraaf JH, Samiei S, Boersma E, Duckers HJ., Intracoronary stem cell infusion after acute myocardial infarction: a meta-analysis and update on clinical trials. Circ Cardiovasc Interv 2014; 7: 156-167. doi: 10.1161/CIRCINTERVENTIONS.113.001009
5. Francis DP, Mielewczik M, Zargaran D, Cole GD., Autologous bone marrow-derived stem cell therapy in heart disease: discrepancies and contradictions. Int J Cardiol 2013; 168: 3381-3403. doi: 10.1016/j.ijcard.2013.04.152
6. Bartunek J, Vanderheyden M, Vandekerckhove B, Mansour S, De Bruyne B, De Bondt P, Van Haute I, Lootens N, Heyndrickx G, Wijns W., Intracoronary injection of CD133-positive enriched bone marrow progenitor cells promotes cardiac recovery after recent myocardial infarction: feasibility and safety. Circulation 2005 112 I178 I183. doi: 10.1161/CIRCULATIONAHA.104.522292
7. Wollert KC, Meyer GP, Lotz J, Ringes-Lichtenberg S, Lippolt P, Breidenbach C, Fichtner S, Korte T, Hornig B, Messinger D, Arseniev L, Hertenstein B, Ganser A, Drexler H., Intracoronary autologous bone-marrow cell transfer after myocardial infarction: the BOOST randomised controlled clinical trial. Lancet 2004; 364: 141-148. doi: 10.1016/S0140-6736(04)16626-9
8. Lunde K, Solheim S, Aakhus S, Intracoronary injection of mononuclear bone marrow cells in acute myocardial infarction. N Engl J Med 2006; 355: 1199-1209. doi: 10.1056/NEJMoa055706
9. Roncalli J, Mouquet F, Piot C, Intracoronary autologous mononucleated bone marrow cell infusion for acute myocardial infarction: results of the randomized multicenter BONAMI trial. Eur Heart J 2011; 32: 1748-1757. doi: 10.1093/eurheartj/ehq455
10. Makkar RR, Smith RR, Cheng K, Intracoronary cardiosphere-derived cells for heart regeneration after myocardial infarction (CADUCEUS): a prospective, randomised phase 1 trial. Lancet 2012; 379: 895-904.
11. Tendera M, Wojakowski W, Ruzyłło W, Chojnowska L, Kepka C, Tracz W, Musiałek P, Piwowarska W, Nessler J, Buszman P, Grajek S, Breborowicz P, Majka M, Ratajczak MZ, REGENT Investigators Intracoronary infusion of bone marrow-derived selected CD34+CXCR4+ cells and non-selected mononuclear cells in patients with acute STEMI and reduced left ventricular ejection fraction: results of randomized, multicentre Myocardial Regeneration by Intracoronary Infusion of Selected Population of Stem Cells in Acute Myocardial Infarction (REGENT) Trial. Eur Heart J 2009; 30: 1313-1321. doi: 10.1093/eurheartj/ehp073
12. Schächinger V, Erbs S, Elsässer A, REPAIR-AMI Investigators Intracoronary bone marrow-derived progenitor cells in acute myocardial infarction. N Engl J Med 2006; 355: 1210-1221.
13. Wöhrle J, Merkle N, Mailänder V, Nusser T, Schauwecker P, von Scheidt F, Schwarz K, Bommer M, Wiesneth M, Schrezenmeier H, Hombach V., Results of intracoronary stem cell therapy after acute myocardial infarction. Am J Cardiol 2010; 105: 804-812. doi: 10.1016/j.amjcard.2009.10.060
14. Miettinen JA, Ylitalo K, Hedberg P, Determinants of functional recovery after myocardial infarction of patients treated with bone marrow-derived stem cells after thrombolytic therapy. Heart 2010; 96: 362-367. doi: 10.1136/hrt.2009.171694
15. Sürder D, Schwitter J, Moccetti T, Cell-based therapy for myocardial repair in patients with acute myocardial infarction: rationale and study design of the SWiss multicenter Intracoronary Stem cells Study in Acute Myocardial Infarction (SWISS-AMI). Am Heart J 2010; 160: 58-64. doi: 10.1016/j.ahj.2010.03.039
16. Traverse JH, Henry TD, Pepine CJ, Cardiovascular Cell Therapy Research Network (CCTRN) Effect of the use and timing of bone marrow mononuclear cell delivery on left ventricular function after acute myocardial infarction: the TIME randomized trial. JAMA 2012; 308: 2380-2389. doi: 10.1001/jama.2012.28726
17. Traverse JH, Henry TD, Ellis SG, Cardiovascular Cell Therapy Research Network Effect of intracoronary delivery of autologous bone marrow mononuclear cells 2 to 3 weeks following acute myocardial infarction on left ventricular function: the LateTIME randomized trial. JAMA 2011; 306: 2110-2119. doi: 10.1001/jama.2011.1670
18. Stroup DF, Berlin JA, Morton SC, Olkin I, Williamson GD, Rennie D, Moher D, Becker BJ, Sipe TA, Thacker SB., Meta-analysis of observational studies in epidemiology: a proposal for reporting. Meta-analysis Of Observational Studies in Epidemiology (MOOSE) group. JAMA 2000; 283: 2008-2012.
19. Higgins JPT, Green S., Cochrane Handbook for Systematic Reviews of Interventions 2008 England John Wiley & Sons Ltd
20. Tudur Smith C, Williamson PR., A comparison of methods for fixed effects meta-analysis of individual patient data with time to event outcomes. Clin Trials 2007; 4: 621-630. doi: 10.1177/1740774507085276
21. Riley RD, Kauser I, Bland M, Thijs L, Staessen JA, Wang J, Gueyffier F, Deeks JJ., Meta-analysis of randomised trials with a continuous outcome according to baseline imbalance and availability of individual participant data. Stat Med 2013; 32: 2747-2766. doi: 10.1002/sim.5726
22. Engblom H, Hedström E, Heiberg E, Wagner GS, Pahlm O, Arheden H., Rapid initial reduction of hyperenhanced myocardium after reperfused first myocardial infarction suggests recovery of the peri-infarction zone: one-year follow-up by MRI. Circ Cardiovasc Imaging 2009; 2: 47-55. doi: 10.1161/CIRCIMAGING.108.802199
23. Cogle CR, Wise E, Meacham AM, Cardiovascular Cell Therapy Research Network (CCTRN) Detailed analysis of bone marrow from patients with ischemic heart disease and left ventricular dysfunction: BM CD34, CD11b, and clonogenic capacity as biomarkers for clinical outcomes. Circ Res 2014; 115: 867-874. doi: 10.1161/CIRCRESAHA.115.304353
24. Reiter R, Swingen C, Moore L, Henry TD, Traverse JH., Circadian dependence of infarct size and left ventricular function after ST elevation myocardial infarction. Circ Res 2012; 110: 105-110. doi: 10.1161/CIRCRESAHA.111.254284
25. Li TS, Cheng K, Malliaras K, Smith RR, Zhang Y, Sun B, Matsushita N, Blusztajn A, Terrovitis J, Kusuoka H, Marbán L, Marbán E., Direct comparison of different stem cell types and subpopulations reveals superior paracrine potency and myocardial repair efficacy with cardiosphere-derived cells. J Am Coll Cardiol 2012; 59: 942-953. doi: 10.1016/j.jacc.2011.11.029
26. Simari RD, Moyé LA, Skarlatos SI, Ellis SG, Zhao DX, Willerson JT, Henry TD, Pepine CJ., Development of a network to test strategies in cardiovascular cell delivery: the NHLBI-sponsored Cardiovascular Cell Therapy Research Network (CCTRN). J Cardiovasc Transl Res 2010; 3: 30-36. doi: 10.1007/s12265-009-9160-3
27. Moyé LA, Henry TD, Baran KW, Cell therapy and satellite centers: the Cardiovascular Cell Therapy Research Network experience. Contemp Clin Trials 2011; 32: 841-847. doi: 10.1016/j.cct.2011.07.001