Economic outcomes with anatomical versus functional diagnostic testing for coronary artery disease

Annals of Internal Medicine

Volumn 165, Issue 2, 2016, Pages 94-102

  Mark, Daniel B ^a   Federspiel, Jerome J ^a   Cowper, Patricia A ^a   Anstrom, Kevin J ^a   Hoffmann, Udo ^b,d   Patel, Manesh R ^a   Davidson Ray, Linda ^a   Daniels, Melanie R ^a   Cooper, Lawton S ^c   Knight, J David ^a   Lee, Kerry L ^a   Douglas, Pamela S ^a   Bonow, Robert ^e   Anderson, Garnet ^f   Bertoni, Alain ^g   Carr, J Jeffrey ^g   Min, James K ^h   Proschan, Michael ⁱ   Spertus, John A ^j   Ulrich, Connie M ^k   Al Khalidi, Hussein R ^a   Bonds, Denise ^c   Cook, Nakela ^c   Dolor, Rowena J ^a   Go, Alan ^l   Fordyce, Christopher ^a   Harding, Tina ^a   Hayden, Sarah ^a   Kosinski, Andrzej ^a   Krucoff, Mitchell W ^a   Leifer, Eric ^c   Martinez, Beth ^a   Mudrick, Daniel W ^a   Picard, Michael H ^d   Rubin, Geoffrey ^a   Salvaggio, Kristen ^d   Schneider, Ricky M ^m,be   Shen, Alexandra ^a   Tardif, Jean Claude ⁿ   Tate, Wanda ^a   Udelson, James E ^o   Vavalle, John ^a   Velazquez, Eric J ^a   Garg, Jyotsna ^gn   Huang, Megan ^gn   Wu, Stephanie ^gn   Yang, Qinghong ^gn   Yow, Eric ^gn   Zhang, Aijing ^gn   Apgar, Charles ^p   Achenbach, Stephan ^q   Corsini, Erin ^d   Ghoshhajra, Brian B ^d   Lu, Michael ^d   Truong, Quynh ^d   Kinan, Debra ^o   Carlos, Edward ^r   Cole, Jason ^s   Johnson, Michael ^t   Krista, Mathew ^u   Ridner, Michael ^v   Abidov, Aiden ^w   Barker, Barbara ^x   Bies, Roger ^x   Jones, David ^y   Weathers, Larry ^z   Albert, Timothy ^aa   Ariani, Kevin ^ab   Banerjee, Supratim ^ac   Budoff, Matthew ^ad   Chang, Donald ^ae   Forman, Steven ^af   Foster, Gary ^ag   Hsu, Joe ^ah   Jang, James ^ah   Kahn, Andrew ^ai   Karlsberg, Ronald ^aj   Krishnam, Mayil ^ak   Lee, Margaret ^al   Lepor, Norman ^am   Loh, Irving ^an   Lurie, Mark ^ao   McConnell, Michael ^ap   Ruehm, Stefan ^al   Vorobiof, Gabriel ^aq   Abramson, Simeon ^ar   Friedrich, Steven ^as   Moloo, Jamaluddin ^at   Treat, Stephen ^au   Keller, Andrew ^av   Yang, Clifford ^aw   Bramlet, Dean ^ax   Braun, Edward ^ax   Foucauld, Jean ^ay   Ghai, Akash ^az   Guzman, Pablo ^ba   Hendel, Robert ^bb   Javier, Julian ^bc   Schmalfuss, Carsten ^bd   Sotolongo, Carlos ^bf   Tannenbaum, Alan ^bf   Weinstock, Barry ^bg   Champney, Kimberly ^bh   Frohwein, Stephen ^bi   Jenkins, Lonnie ^bj   Koganti, Devendra ^bk   Litwin, Sheldon ^bl   Shapiro, Patricia ^bm   Leung, Cyril ^ah   Hinchman, David ^bn   Clark, Stanley ^bo   Danciu, Sorin ^bp   Hines, Jerome ^bq   Patel, Amit ^br   Sullivan, Daniel ^bo   Trivedi, Dinker ^bs   Vidovich, Mladen ^bt   Mahenthiran, Jo ^bu   Shaikh, Saeed ^bv   Teague, Shawn ^bw   Clark, Craig ^bx   Martin, Enrico ^by   Sigurdsson, Gardar ^bz   Bloom, Steve ^ca   Hagley, Michael ^cb   Schmidt, William ^cc   Sorrell, Vincent ^cd   Turner, Michael ^ce   Weiss, Robert ^cf   Hearne, Steven ^cg   Jerome, Scott ^ch   Morss, Alexander ^ci   Ruberg, Rick ^cj   Abdul Nour, Khaled ^ck   Chinnaiyan, Kavitha ^cl   Goraya, Tauqir ^cm   Heath, John ^cl   Meengs, Mark ^cn   Nahhas, George ^co   Nounou, Majed ^cp   Saba, Souheil ^cq   Sallach, Susan ^cr   Ginete, Wilson ^cs   Helmer, Gregory ^ct   McLaurin, Mary ^cu   Pellikka, Patricia ^cv   Pelzel, Jamie ^cw   Carroll, William ^cx   Martin, Arthur ^cy   Rivard, Andrew ^cz   Ciaramita, Jeffrey ^da   Hawa, Zafir ^db   Woodard, Pamela ^dc   Jehle, Alexander ^dd   Delcore, Michael ^de   Porter, Thomas ^df   Van De Graaff, Eric ^dg   Budhwani, Navin ^dh   Bullock Palmer, Renee ^di   Espinoza, Andrey ^dj   Kostis, John ^dk   Mustafa, Muhammad ^dl   Cavanaugh, Brendan ^dm   Cohen, Randy ^dn   Donnino, Robert ^do   Garcia, Mario ^dp   Goodman, Dennis ^dq   Heitner, John ^dr   Kamran, Mazullah ^ds   Lader, Ellis ^dt   Marmulstein, Michael ^du   Menzies, Dhananjai ^dv   Morris, Robert ^dl   Page, Brian ^dw   Park, Chong ^dx   Poon, Michael ^dy   Wilson, Michael ^dz   Atieh, Mahmoud ^ea   Bohle, David ^eb   Dulin, Michael ^ec   Gring, Christian ^ed   Hakas, Joseph ^ee   McLean, Dalton ^aj   Rorie, Mark ^ef   Sharkey, Kevin ^eg   Almanaseer, Yassar ^eh   Dirkes, William ^ei   Goldberg, Jonathan ^ej   Iler, Mark ^ek   Kutoloski, Karen ^el   Maaieh, Mohammed ^em   Mashny, John ^en   Pelberg, Robert ^eo   Richards, David ^ep   Tinkel, Jodi ^eq   Chrysant, George ^er   Des Prez, Roger ^es   Hill, Gregory ^et   Hussain, Iftikhar ^eu   Shapiro, Michael ^ev   Allen, Christopher ^ew   Babayan, Zaruhi ^ex   Bauch, Terry ^ey   Berliner, Jennifer ^bd   Bove, Alfred ^ez   Fox, Donald ^fa   Jacob, Ron ^fb   Jamis Dow, Carlos ^fc   Nadar, Venkatesh ^fd   Phiambolis, Thomas ^fe   Gregg, David ^ff   Isbell, David ^fg   Johnson, Steven ^fh   Kumar, Priya ^fi   Hiremagalur, Shobha ^fj   Huneycutt, David ^fk   Korban, Elie ^fl   Severance, Harry ^fm   Banerjee, Subhash ^fn   Baweja, Gurpreet ^fo   Erwin, John ^fp   Gigliotti, Osvaldo ^fq   Khan, Muhammad ^fr   Lieber, Ira ^fs   Navetta, Frank ^ft   Osborne, John ^fu   Slim, Ahmad ^fv   Wilks, Richard ^fw   George, Anu ^fx   Hartman, Aaron ^fy   Levitt, Robert ^fz   Phillips, Charles ^ga   Salerno, Michael ^ga   Schietinger, Brian ^gb   Slowikowski, Jack ^gc   Malhotra, Vinay ^gd   Waggoner, L Douglas ^ge   Carter, William ^gf   Liberman, Joshua ^gg   Logemann, Timothy ^gh   Manley, John ^gi   Port, Steve ^gj   Zasadil, Mary ^gk   Chow, Benjamin ^gl   Larose, Eric ^gm   more..

^a DUKE CLINICAL RESEARCH INSTITUTE   (United States)

^b Radiological Asociates   (United States)

^c NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^d MASSACHUSETTS GENERAL HOSPITAL   (United States)

^e NORTHWESTERN UNIVERSITY   (United States)

^f Fred Hutchinson Cancer Research Center   (United States)

^g WAKE FOREST SCHOOL OF MEDICINE   (United States)

^h WEILL CORNELL MEDICAL CENTER   (United States)

ⁱ NATIONAL INSTITUTES OF HEALTH   (United States)

^j WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^k UNIVERSITY OF PENNSYLVANIA   (United States)

^l DIVISION OF RESEARCH   (United States)

^m HOLY CROSS HOSPITAL   (United States)

ⁿ MONTREAL HEART INSTITUTE   (Canada)

^o TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^p AMERICAN COLLEGE OF RADIOLOGY   (United States)

^q UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^r Sunbelt Research Group   (Germany)

^s Cardiology Asociates   (Germany)

^t North Huntsville Family Care   (Germany)

^u Prime Care   (Germany)

^v Heart Center   (Germany)

^w Bonn   (Germany)

^x Mercy Gilbert Medical Center   (United States)

^y Arkansas Cardiology   (United States)

^z Mercy Heart and Vascular Center   (United States)

^aa Salinas Valley Memorial Hospital   (United States)

^ab Northridge Hospital Medical Center   (United States)

^ac Comprehensive Cardiovascular Medical Group ^*  (United States)

^ad Los Angeles Biomedical Research Institute   (United States)

^ae VA GREATER LOS ANGELES HEALTHCARE SYSTEM   (United States)

^af Los Alamitos Cardiovascular   (United States)

^ag Jerry L Pettis Memorial VA Medical Center   (United States)

^ah KAISER PERMANENTE   (United States)

^ai UNIVERSITY OF CALIFORNIA   (United States)

^aj CARDIOVASCULAR RESEARCH FOUNDATION   (United States)

^ak UNIVERSITY OF CALIFORNIA   (United States)

^al UCLA MEDICAL CENTER   (United States)

^am Westside Medical Associates   (United States)

^an Westlake Medical Research   (United States)

^ao Memorial Medical Center   (United States)

^ap STANFORD UNIVERSITY MEDICAL CENTER   (United States)

^aq MIS   (United States)

^ar Porter Adventist Hospital   (United States)

^as South Denver Cardiology Asociates   (United States)

^at Health Sciences Center   (United States)

^au Medical Center of Rockies   (United States)

^av DANBURY HOSPITAL   (United States)

^aw UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

^ax Department of Pathology Mount Sinai   (United States)

^ay Cardiology Partners Research Institute   (United States)

^az Tallahassee Research Institute   (United States)

^ba Cardiology Associates of Fort Lauderdale   (United States)

^bb UNIVERSITY OF MIAMI HOSPITAL   (United States)

^bc Pharma Research International   (United States)

^bd VETERANS AFFAIRS MEDICAL CENTER   (United States)

^be Holy Cross Medical Group   (United States)

^bf Primary Care Asociates   (United States)

^bg ORLANDO REGIONAL MEDICAL CENTER   (United States)

^bh NORTHSIDE HOSPITAL   (United States)

^bi Saint Joseph's Hospital of Atlanta   (United States)

^bj Synergy Therapeutic Partners   (United States)

^bk Southern Heart Research Institute   (United States)

^bl AUGUSTA UNIVERSITY   (United States)

^bm South Coast Medical Group   (United States)

^bn St Luke's Boise Medical Center   (United States)

^bo Midwest Heart Foundation   (United States)

^bp Lutheran General Hospital   (United States)

^bq Illinois Heart and Vascular   (United States)

^br UNIVERSITY OF CHICAGO MEDICAL CENTER   (United States)

^bs ADVOCATE CHRIST MEDICAL CENTER   (United States)

^bt UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^bu The Indiana Heart Hospital   (United States)

^bv Indiana Heart Physicians   (United States)

^bw INDIANA UNIVERSITY HEALTH   (United States)

^bx Radiology Consultants of Iowa   (United States)

^by IOWA HEART CENTER   (United States)

^bz UNIVERSITY OF IOWA HOSPITALS AND CLINICS   (United States)

^ca Midwest Cardiology Associates   (United States)

^cb Landstuhl Regional Medical Center   (United States)

^cc Norton Cardiovascular Associates   (United States)

^cd UNIVERSITY OF KENTUCKY   (United States)

^ce Southwest Louisiana   (United States)

^cf Maine Research Associates   (United States)

^cg Delmarva Heart   (United States)

^ch UNIVERSITY OF MARYLAND   (United States)

^ci South Shore Hospital   (United States)

^cj BOSTON MEDICAL CENTER   (United States)

^ck HENRY FORD HEALTH SYSTEM   (United States)

^cl WILLIAM BEAUMONT HOSPITAL   (United States)

^cm Michigan Heart   (United States)

^cn Department of Emergency Medicine   (United States)

^co OAKWOOD HOSPITAL AND MEDICAL CENTER   (United States)

^cp Cardiology Consultants of East Michigan   (United States)

^cq Craniofacial Institute of Michigan   (United States)

^cr Michigan Cardiovascular Institute   (United States)

^cs Essentia Health Saint Mary's Medical Center   (United States)

^ct University of Minnesota Heart Care   (United States)

^cu NORTH MEMORIAL MEDICAL CENTER   (United States)

^cv MAYO CLINIC   (United States)

^cw U of MN St Cloud Hospital FMR   (United States)

^cx Cardiology Associates of North Mississippi   (United States)

^cy Hattiesburg Clinic   (United States)

^cz UNIVERSITY OF MISSISSIPPI MEDICAL CENTER   (United States)

^da Saint John's Mercy Heart Hospital   (United States)

^db North kansas City Hospital   (United States)

^dc BARNES JEWISH HOSPITAL   (United States)

^dd St Patrick Hospital and Health Sciences Center   (United States)

^de CREIGHTON UNIVERSITY   (United States)

^df UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^dg Alegent Midlands Community Hospital   (United States)

^dh Valley Hospital   (United States)

^di DEBORAH HEART AND LUNG CENTER   (United States)

^dj Hunterdon Medical Center   (United States)

^dk RUTGERS ROBERT WOOD JOHNSON MEDICAL SCHOOL   (United States)

^dl Capital Cardiology Associates   (United States)

^dm New Mexico Heart Institute   (United States)

^dn ST LUKE S ROOSEVELT HOSPITAL CENTER   (United States)

^do DEPARTMENT OF VETERANS AFFAIRS   (United States)

^dp MONTEFIORE MEDICAL CENTER   (United States)

^dq New York Medical School   (United States)

^dr NEW YORK METHODIST HOSPITAL   (United States)

^ds Elmhurst Hospital   (United States)

^dt Mid Valley Cardiology   (United States)

^du Albany Associates in Cardiology   (United States)

^dv BASSETT MEDICAL CENTER   (United States)

^dw UNIVERSITY AT BUFFALO   (United States)

^dx NEW YORK PRESBYTERIAN HOSPITAL   (United States)

^dy STONY BROOK UNIVERSITY MEDICAL CENTER   (United States)

^dz Millard Fillmore Suburban Hospital   (United States)

^ea Sanford Cardiology   (United States)

^eb FORSYTH MEDICAL CENTER   (United States)

^ec CAROLINAS MEDICAL CENTER   (United States)

^ed Wake Heart and Vascular Associates   (United States)

^ee Pinehurst Medical Clinic   (United States)

^ef Asheville Cardiology Associates   (United States)

^eg Novant Heart Vascular Institute   (United States)

^eh Essentia Health   (United States)

^ei Sentral Clinical Research Services   (United States)

^ej LOUIS STOKES CLEVELAND VA MEDICAL CENTER   (United States)

^ek SUMMA HEALTH SYSTEM   (United States)

^el Metro Health Hospital   (United States)

^em Northwest Ohio Cardiology Consultants   (United States)

^en Bethesda North Hospital   (United States)

^eo Lindner Clinical Trial Center   (United States)

^ep RIVERSIDE METHODIST HOSPITAL   (United States)

^eq UNIVERSITY OF TOLEDO   (United States)

^er INTEGRIS BAPTIST MEDICAL CENTER   (United States)

^es Oklahoma Heart Institute   (United States)

^et Saint Francis Hospital   (United States)

^eu Vital Prospects Clinical Research Institute PC   (United States)

^ev OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^ew Donahue Cardiology Associates   (United States)

^ex GUTHRIE RESEARCH INSTITUTE   (United States)

^ey GEISINGER MEDICAL CENTER   (United States)

^ez TEMPLE UNIVERSITY HOSPITAL   (United States)

^fa Eastwick Primary Care   (United States)

^fb Lancaster Heart and Stroke Foundation   (United States)

^fc PENN STATE MILTON S HERSHEY MEDICAL CENTER   (United States)

^fd Capital Area Research   (United States)

^fe Lankenau Medical Center   (United States)

^ff MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^fg Eastwick Primary Care ^*  (United States)

^fh Upstate Cardiology   (United States)

^fi Piedmont Cardiology Associates   (United States)

^fj Blue Ridge Medical Management Corporation   (United States)

^fk Centennial Heart Cardiovascular Consultants   (United States)

^fl Kore Cardiovascular Research   (United States)

^fm Erlanger Medical Center   (United States)

^fn VA NORTH TEXAS HEALTH CARE SYSTEM   (United States)

^fo Texas Health Research and Education Institute   (United States)

^fp SCOTT AND WHITE MEMORIAL HOSPITAL   (United States)

^fq Seton Medical Center   (United States)

^fr North Dallas Research   (United States)

^fs Texas Cardiology Associates of Houston   (United States)

^ft Tyler Cardiovascular Consultants   (United States)

^fu State of the Heart Cardiology   (United States)

^fv BROOKE ARMY MEDICAL CENTER   (United States)

^fw BHS Specialty Network   (United States)

^fx Seven Corners Medical Center   (United States)

^fy Virginia Breast Center   (United States)

^fz National Clinical Research   (United States)

^ga UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

^gb Centra Health   (United States)

^gc Carilion Clinic Cardiac Research   (United States)

^gd Cardiac Study Center   (United States)

^ge Kootenai Heart Clinics   (United States)

^gf CHARLESTON AREA MEDICAL CENTER   (United States)

^gg Wisconsin Cardiovascular Group   (United States)

^gh Aspirus Heart and Vascular Institute   (United States)

^gi The Wisconsin Heart Hospital   (United States)

^gj Aurora Cardiovascular Services   (United States)

^gk UNIVERSITY OF WISCONSIN MADISON   (United States)

^gl UNIVERSITY OF OTTAWA HEART INSTITUTE   (Canada)

^gm LAVAL UNIVERSITY   (Canada)

^gn Aspirus Heart and Vascular Institute ^*

more..

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BOOTSTRAPPING; CATHETERIZATION; CORONARY ARTERY DISEASE; EXERCISE ELECTROCARDIOGRAPHY; FEMALE; FOLLOW UP; HEART MUSCLE REVASCULARIZATION; HOSPITAL COST; HUMAN; INTENTION TO TREAT ANALYSIS; MAJOR CLINICAL STUDY; MALE; MEDICAL FEE; MEDICARE; OUTPATIENT; PRIORITY JOURNAL; PROBABILITY; PROSPECTIVE STUDY; STRESS ECHOCARDIOGRAPHY; TREATMENT DURATION; AGED; CHEST PAIN; CLINICAL TRIAL; CORONARY ANGIOGRAPHY; DIAGNOSTIC IMAGING; ECONOMICS; ELECTROCARDIOGRAPHY; EXERCISE TEST; HEART FUNCTION TEST; MIDDLE AGED; MULTICENTER STUDY; MULTIDETECTOR COMPUTED TOMOGRAPHY; PROCEDURES;

AGED; CHEST PAIN; CORONARY ANGIOGRAPHY; CORONARY ARTERY DISEASE; ECHOCARDIOGRAPHY, STRESS; ELECTROCARDIOGRAPHY; EXERCISE TEST; FEES, MEDICAL; FEMALE; HEART FUNCTION TESTS; HOSPITAL COSTS; HUMANS; MALE; MIDDLE AGED; MULTIDETECTOR COMPUTED TOMOGRAPHY; PROSPECTIVE STUDIES;

EID: 84979520669     PISSN: 00034819     EISSN: 15393704     Source Type: Journal    
DOI: 10.7326/M15-2639     Document Type: Article

References (13)

1. Nielsen LH, Ortner N, Nørgaard BL, Achenbach S, Leipsic J, Abdulla J. The diagnostic accuracy and outcomes after coronary computed tomography angiography vs. conventional functional testing in patients with stable angina pectoris: a systematic review and metaanalysis. Eur Heart J Cardiovasc Imaging. 2014;15:961-71. [PMID: 24618659] doi:10.1093/ehjci/jeu027
2. Mahajan N, Polavaram L, Vankayala H, Ference B, Wang Y, Ager J, et al. Diagnostic accuracy of myocardial perfusion imaging and stress echocardiography for the diagnosis of left main and triple vessel coronary artery disease: a comparative meta-analysis. Heart. 2010;96:956-66. [PMID: 20538671] doi:10.1136/hrt.2009.182295
3. Metz LD, Beattie M, Hom R, Redberg RF, Grady D, Fleischmann KE. The prognostic value of normal exercise myocardial perfusion imaging and exercise echocardiography: a meta-analysis. J Am Coll Cardiol. 2007;49:227-37. [PMID: 17222734]
4. Mowatt G, Vale L, Brazzelli M, Hernandez R, Murray A, Scott N, et al. Systematic review of the effectiveness and cost-effectiveness, and economic evaluation, of myocardial perfusion scintigraphy for the diagnosis and management of angina and myocardial infarction. Health Technol Assess. 2004;8:1-207. [PMID: 15248938]
5. Douglas PS, Hoffmann U, Patel MR, Mark DB, Al-Khalidi HR, Cavanaugh B, et al; PROMISE Investigators. Outcomes of anatomical versus functional testing for coronary artery disease. N Engl J Med. 2015;372:1291-300. [PMID: 25773919] doi:10.1056/NEJMoa1415516
6. Douglas PS, Hoffmann U, Lee KL, Mark DB, Al-Khalidi HR, Anstrom K, et al; PROMISE investigators. PROspective Multicenter Imaging Study for Evaluation of chest pain: rationale and design of the PROMISE trial. Am Heart J. 2014;167:796-803. [PMID: 24890527] doi:10.1016/j.ahj.2014.03.003
7. Mark DB, Hlatky MA. Medical economics and the assessment of value in cardiovascular medicine: Part I. Circulation. 2002;106:516-20. [PMID: 12135955]
8. Bang H, Tsiatis AA. Estimating medical costs with censored data. Biometrika. 2000;87:329-43.
9. Fihn SD, Gardin JM, Abrams J, Berra K, Blankenship JC, Dallas AP, et al; American College of Cardiology Foundation. 2012 ACCF/AHA/ACP/AATS/PCNA/SCAI/STS Guideline for the diagnosis and management of patients with stable ischemic heart disease: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines, and the American College of Physicians, American Association for Thoracic Surgery, Preventive Cardiovascular Nurses Association, Society for Cardiovascular Angiography and Interventions, and Society of Thoracic Surgeons. J Am Coll Cardiol. 2012;60:e44-e164. [PMID: 23182125] doi: 10.1016/j.jacc.2012.07.013
10. Chow BJ, Abraham A, Wells GA, Chen L, Ruddy TD, Yam Y, et al. Diagnostic accuracy and impact of computed tomographic coronary angiography on utilization of invasive coronary angiography. Circ Cardiovasc Imaging. 2009;2:16-23. [PMID: 19808560] doi:10.1161/CIRCIMAGING.108.792572
11. Shreibati JB, Baker LC, Hlatky MA. Association of coronary CT angiography or stress testing with subsequent utilization and spending among Medicare beneficiaries. JAMA. 2011;306:2128-36. [PMID: 22089720] doi:10.1001/jama.2011.1652
12. Hlatky MA, Shilane D, Hachamovitch R, Dicarli MF; SPARC Investigators. Economic outcomes in the Study of Myocardial Perfusion and Coronary Anatomy Imaging Roles in Coronary Artery Disease registry: the SPARC Study. J Am Coll Cardiol. 2014;63:1002-8. [PMID: 24636556] doi:10.1016/j.jacc.2013.11.038
13. Hlatky MA, De Bruyne B, Pontone G, Patel MR, Norgaard BL, Byrne RA, et al; PLATFORM Investigators. Quality-of-life and economic outcomes of assessing fractional flow reserve with computed tomography angiography: PLATFORM. J Am Coll Cardiol. 2015;66: 2315-23. [PMID: 26475205] doi:10.1016/j.jacc.2015.09.051