Polygenic risk score is associated with increased disease risk in 52 Finnish breast cancer families

Breast Cancer Research and Treatment

Volumn 158, Issue 3, 2016, Pages 463-469

  Muranen, Taru A ^a   Mavaddat, Nasim ^b   Khan, Sofia ^a   Fagerholm, Rainer ^a   Pelttari, Liisa ^a   Lee, Andrew ^b   Aittomäki, Kristiina ^a   Blomqvist, Carl ^a   Easton, Douglas F ^b   Nevanlinna, Heli ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Breast cancer; Common variants; Hereditary; PRS; Risk

Indexed keywords

ESTROGEN RECEPTOR;

AGE; ARTICLE; BREAST CANCER; CANCER RISK; CASE CONTROL STUDY; CONTROLLED STUDY; FAMILY HISTORY; FEMALE; FINN (CITIZEN); GENETIC ASSOCIATION; GENETIC VARIABILITY; HUMAN; MAJOR CLINICAL STUDY; POLYGENIC RISK SCORE; PRIORITY JOURNAL; RISK ASSESSMENT; SCORING SYSTEM; ALGORITHM; BREAST TUMOR; FINLAND; GENETIC PREDISPOSITION; GENETIC VARIATION; GENETICS; GENOTYPING TECHNIQUE; MULTIFACTORIAL INHERITANCE; PEDIGREE; PROCEDURES;

ALGORITHMS; BREAST NEOPLASMS; CASE-CONTROL STUDIES; FEMALE; FINLAND; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; GENOTYPING TECHNIQUES; HUMANS; MULTIFACTORIAL INHERITANCE; PEDIGREE;

EID: 84979263776     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-016-3897-6     Document Type: Article

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