Antibiotic-loaded, silver core-embedded mesoporous silica nanovehicles as a synergistic antibacterial agent for the treatment of drug-resistant infections

Biomaterials

Volumn 101, Issue , 2016, Pages 207-216

  Wang, Yao ^a   Ding, Xiali ^b   Chen, Yuan ^a   Guo, Mingquan ^b   Zhang, Yan ^b   Guo, Xiaokui ^b   Gu, Hongchen ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Antibacterial nanoplatform; Antibiotic; Drug resistant infections; Silver; Synergistic effect

Indexed keywords

ANTIBIOTICS; ESCHERICHIA COLI; HEALTH RISKS; MAMMALS; PUBLIC RISKS; SILICA;

ANTI-BACTERIAL ACTIVITY; ANTIBACTERIAL NANOPLATFORM; BACTERIAL INFECTIONS; DRUG-RESISTANT BACTERIA; DRUG-RESISTANT INFECTIONS; SYNERGISTIC EFFECT; THREE ORDERS OF MAGNITUDE; TOXIC SIDE EFFECTS;

SILVER;

LEVOFLOXACIN; MESOPOROUS SILICA NANOPARTICLE; SILVER NANOPARTICLE; ANTIINFECTIVE AGENT; NANOCAPSULE; SILICON DIOXIDE; SILVER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL PERITONITIS; BACTERIAL STRAIN; DRUG RELEASE; DRUG RESISTANT BACTERIAL INFECTION; DRUG SAFETY; ESCHERICHIA COLI; FEMALE; IN VITRO STUDY; IN VIVO STUDY; MINIMUM INHIBITORY CONCENTRATION; MOUSE; NONHUMAN; PERITONEAL CAVITY; PRIORITY JOURNAL; SPLEEN; TRANSMISSION ELECTRON MICROSCOPY; ANIMAL; BAGG ALBINO MOUSE; CHEMISTRY; DRUG EFFECTS; ESCHERICHIA COLI INFECTION; HUMAN; KLEBSIELLA INFECTION; KLEBSIELLA PNEUMONIAE; MICROBIOLOGY; PERITONITIS; ULTRASTRUCTURE;

ANIMALS; ANTI-BACTERIAL AGENTS; DRUG RESISTANCE, BACTERIAL; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; FEMALE; HUMANS; KLEBSIELLA INFECTIONS; KLEBSIELLA PNEUMONIAE; LEVOFLOXACIN; MICE, INBRED BALB C; NANOCAPSULES; PERITONITIS; SILICON DIOXIDE; SILVER;

EID: 84979220727     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2016.06.004     Document Type: Article

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