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Volumn 53, Issue 6, 2016, Pages 3753-3755

Inhibition of Protein Phosphatase 2A: Focus on the Glutamatergic System

Author keywords

Excitotoxicity; Glutamate; Okadaic acid; Protein phosphatase 2A; Tau hyperphosphorylation

Indexed keywords

CYCLIN DEPENDENT KINASE 5; GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; OKADAIC ACID; PHOSPHOPROTEIN PHOSPHATASE 2A; ENZYME INHIBITOR; PHOSPHOPROTEIN PHOSPHATASE 2;

EID: 84979082782     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-015-9321-0     Document Type: Review
Times cited : (11)

References (14)
  • 1
    • 0027214404 scopus 로고
    • Phosphoprotein phosphatase activities in Alzheimer disease brain
    • COI: 1:CAS:528:DyaK2cXivVKisQ%3D%3D, PID: 8395566
    • Gong CX, Singh TJ, Grundke-Iqbal I, Iqbal K (1993) Phosphoprotein phosphatase activities in Alzheimer disease brain. J Neurochem 61(3):921–927
    • (1993) J Neurochem , vol.61 , Issue.3 , pp. 921-927
    • Gong, C.X.1    Singh, T.J.2    Grundke-Iqbal, I.3    Iqbal, K.4
  • 2
    • 0028350740 scopus 로고
    • Dephosphorylation of microtubule-associated protein tau by protein phosphatase-1 and -2C and its implication in Alzheimer disease
    • COI: 1:CAS:528:DyaK2cXis1Ogtbo%3D, PID: 8137929
    • Gong CX, Grundke-Iqbal I, Damuni Z, Iqbal K (1994) Dephosphorylation of microtubule-associated protein tau by protein phosphatase-1 and -2C and its implication in Alzheimer disease. FEBS Lett 341(1):94–98
    • (1994) FEBS Lett , vol.341 , Issue.1 , pp. 94-98
    • Gong, C.X.1    Grundke-Iqbal, I.2    Damuni, Z.3    Iqbal, K.4
  • 4
    • 84899150245 scopus 로고    scopus 로고
    • In vivo tracking of tau pathology using positron emission tomography (PET) molecular imaging in small animals
    • Zimmer ER, Leuzy A, Bhat V, Gauthier S, Rosa-Neto P (2014) In vivo tracking of tau pathology using positron emission tomography (PET) molecular imaging in small animals. Transl Neurodegen 3(1):6. doi:10.1186/2047-9158-3-6
    • (2014) Transl Neurodegen , vol.3 , Issue.1 , pp. 6
    • Zimmer, E.R.1    Leuzy, A.2    Bhat, V.3    Gauthier, S.4    Rosa-Neto, P.5
  • 5
    • 84897401611 scopus 로고    scopus 로고
    • Protein phosphatase 2A dysfunction in Alzheimer’s disease
    • PID: 24653673
    • Sontag JM, Sontag E (2014) Protein phosphatase 2A dysfunction in Alzheimer’s disease. Front Mol Neurosci 7:16. doi:10.3389/fnmol.2014.00016
    • (2014) Front Mol Neurosci , vol.7 , pp. 16
    • Sontag, J.M.1    Sontag, E.2
  • 6
    • 84892941950 scopus 로고    scopus 로고
    • Tau pathology involves protein phosphatase 2A in parkinsonism-dementia of Guam
    • COI: 1:CAS:528:DC%2BC2cXhtlegtrs%3D, PID: 24395787
    • Arif M, Kazim SF, Grundke-Iqbal I, Garruto RM, Iqbal K (2014) Tau pathology involves protein phosphatase 2A in parkinsonism-dementia of Guam. Proc Natl Acad Sci U S A 111(3):1144–1149. doi:10.1073/pnas.1322614111
    • (2014) Proc Natl Acad Sci U S A , vol.111 , Issue.3 , pp. 1144-1149
    • Arif, M.1    Kazim, S.F.2    Grundke-Iqbal, I.3    Garruto, R.M.4    Iqbal, K.5
  • 7
    • 84897358323 scopus 로고    scopus 로고
    • Molecular and cellular mechanism of okadaic acid (OKA)-induced neurotoxicity: a novel tool for Alzheimer’s disease therapeutic application
    • COI: 1:CAS:528:DC%2BC2cXlslWisLk%3D, PID: 24710687
    • Kamat PK, Rai S, Swarnkar S, Shukla R, Nath C (2014) Molecular and cellular mechanism of okadaic acid (OKA)-induced neurotoxicity: a novel tool for Alzheimer’s disease therapeutic application. Mol Neurobiol 50(3):852–865. doi:10.1007/s12035-014-8699-4
    • (2014) Mol Neurobiol , vol.50 , Issue.3 , pp. 852-865
    • Kamat, P.K.1    Rai, S.2    Swarnkar, S.3    Shukla, R.4    Nath, C.5
  • 8
    • 0024361302 scopus 로고
    • An improved procedure for identifying and quantitating protein phosphatases in mammalian tissues
    • COI: 1:CAS:528:DyaL1MXlt12nt7g%3D, PID: 2546812
    • Cohen P, Klumpp S, Schelling DL (1989) An improved procedure for identifying and quantitating protein phosphatases in mammalian tissues. FEBS Lett 250(2):596–600
    • (1989) FEBS Lett , vol.250 , Issue.2 , pp. 596-600
    • Cohen, P.1    Klumpp, S.2    Schelling, D.L.3
  • 9
    • 0034088846 scopus 로고    scopus 로고
    • Phosphorylation of microtubule-associated protein tau is regulated by protein phosphatase 2A in mammalian brain. Implications for neurofibrillary degeneration in Alzheimer’s disease
    • COI: 1:CAS:528:DC%2BD3cXhsFKktr4%3D, PID: 10681533
    • Gong CX, Lidsky T, Wegiel J, Zuck L, Grundke-Iqbal I, Iqbal K (2000) Phosphorylation of microtubule-associated protein tau is regulated by protein phosphatase 2A in mammalian brain. Implications for neurofibrillary degeneration in Alzheimer’s disease. J Biol Chem 275(8):5535–5544
    • (2000) J Biol Chem , vol.275 , Issue.8 , pp. 5535-5544
    • Gong, C.X.1    Lidsky, T.2    Wegiel, J.3    Zuck, L.4    Grundke-Iqbal, I.5    Iqbal, K.6
  • 10
    • 27644478606 scopus 로고    scopus 로고
    • Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation
    • Liu F, Grundke-Iqbal I, Iqbal K, Gong CX (2005) Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation. Euro J Neurosci 22(8):1942–1950. doi:10.1111/j.1460-9568.2005.04391.x
    • (2005) Euro J Neurosci , vol.22 , Issue.8 , pp. 1942-1950
    • Liu, F.1    Grundke-Iqbal, I.2    Iqbal, K.3    Gong, C.X.4
  • 11
    • 84874916126 scopus 로고    scopus 로고
    • Pretreatment with memantine prevents Alzheimer-like alterations induced by intrahippocampal okadaic acid administration in rats
    • COI: 1:CAS:528:DC%2BC3sXit1ymuro%3D, PID: 22515493
    • Zimmer ER, Kalinine E, Haas CB, Torrez VR, Souza DO, Muller AP, Portela LV (2012) Pretreatment with memantine prevents Alzheimer-like alterations induced by intrahippocampal okadaic acid administration in rats. Curr Alzheimer Res 9(10):1182–1190
    • (2012) Curr Alzheimer Res , vol.9 , Issue.10 , pp. 1182-1190
    • Zimmer, E.R.1    Kalinine, E.2    Haas, C.B.3    Torrez, V.R.4    Souza, D.O.5    Muller, A.P.6    Portela, L.V.7
  • 12
    • 84905054650 scopus 로고    scopus 로고
    • Mechanism of synapse redox stress in Okadaic acid (ICV) induced memory impairment: role of NMDA receptor
    • COI: 1:CAS:528:DC%2BC2cXht1yms7vL, PID: 24984170
    • Kamat PK, Rai S, Swarnkar S, Shukla R, Nath C (2014) Mechanism of synapse redox stress in Okadaic acid (ICV) induced memory impairment: role of NMDA receptor. Neurochem Int 76:32–41. doi:10.1016/j.neuint.2014.06.012
    • (2014) Neurochem Int , vol.76 , pp. 32-41
    • Kamat, P.K.1    Rai, S.2    Swarnkar, S.3    Shukla, R.4    Nath, C.5
  • 13
    • 84898603240 scopus 로고    scopus 로고
    • Activity-dependent p25 generation regulates synaptic plasticity and Abeta-induced cognitive impairment
    • COI: 1:CAS:528:DC%2BC2cXmslamu7Y%3D, PID: 24725413
    • Seo J, Giusti-Rodriguez P, Zhou Y, Rudenko A, Cho S, Ota KT, Park C, Patzke H et al (2014) Activity-dependent p25 generation regulates synaptic plasticity and Abeta-induced cognitive impairment. Cell 157(2):486–498. doi:10.1016/j.cell.2014.01.065
    • (2014) Cell , vol.157 , Issue.2 , pp. 486-498
    • Seo, J.1    Giusti-Rodriguez, P.2    Zhou, Y.3    Rudenko, A.4    Cho, S.5    Ota, K.T.6    Park, C.7    Patzke, H.8
  • 14
    • 33747423612 scopus 로고    scopus 로고
    • Memantine: a review of its use in Alzheimer’s disease
    • COI: 1:CAS:528:DC%2BD28XhtVeqtL7N, PID: 16906789
    • Robinson DM, Keating GM (2006) Memantine: a review of its use in Alzheimer’s disease. Drugs 66(11):1515–1534
    • (2006) Drugs , vol.66 , Issue.11 , pp. 1515-1534
    • Robinson, D.M.1    Keating, G.M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.