Effect of maternal age on maternal and neonatal outcomes after assisted reproductive technology

Fertility and Sterility

Volumn 106, Issue 5, 2016, Pages 1142-1149.e14

  Wennberg, Anna Lena ^a,b   Opdahl, Signe ^c,d   Bergh, Christina ^a   Aaris Henningsen, Anna Karina ^e   Gissler, Mika ^f   Romundstad, Liv Bente ^c,d,g   Pinborg, Anja ^h   Tiitinen, Aila ⁱ   Skjærven, Rolv ^j,k   Wennerholm, Ulla Britt ^a  

^a SAHLGRENSKA ACADEMY AT UNIVERSITY OF GOTHENBURG   (Sweden)

^b Nordic IVF Center   (Sweden)

^c NORWEGIAN UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Norway)

^d Central Norway Regional Health Authority ^*  (Norway)

^e University of Copenhagen   (Denmark)

^f NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

^g Spiren Fertility Clinic   (Norway)

^h HVIDOVRE HOSPITAL   (Denmark)

ⁱ HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^j UNIVERSITY OF BERGEN   (Norway)

^k NORWEGIAN INSTITUTE OF PUBLIC HEALTH   (Norway)

more..

Author keywords

ART; Assisted reproductive technologies; maternal age; maternal complications; neonatal complications; spontaneous conception

Indexed keywords

ADULT; ADVERSE OUTCOME; ARTICLE; BIRTH; CESAREAN SECTION; COHORT ANALYSIS; CONCEPTION; CONTROLLED STUDY; FEMALE; HIGH RISK PREGNANCY; HUMAN; HUMAN CELL; INFERTILITY THERAPY; LOW BIRTH WEIGHT; MACROSOMIA; MAJOR CLINICAL STUDY; MALE; MATERNAL AGE; MATERNAL HYPERTENSION; MATERNAL OUTCOME; MIDDLE AGED; NEONATAL OUTCOME; NEWBORN; OBSTETRIC DELIVERY; PARAMETERS CONCERNING THE FETUS, NEWBORN AND PREGNANCY; PERINATAL MORTALITY; PLACENTA PREVIA; POPULATION RESEARCH; PREGNANCY OUTCOME; PREGNANT WOMAN; PREMATURE LABOR; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SMALL FOR DATE INFANT; SOLUTIO PLACENTAE; VERY LOW BIRTH WEIGHT; ADVERSE EFFECTS; BIRTH WEIGHT; CLINICAL TRIAL; FERTILITY; GESTATIONAL AGE; INFERTILITY; LIVE BIRTH; MULTICENTER STUDY; ODDS RATIO; PATHOPHYSIOLOGY; PREGNANCY; PREGNANCY COMPLICATIONS; PREMATURE BIRTH; PREMATURITY; REGISTER; RISK ASSESSMENT; RISK FACTOR; SCANDINAVIA; STATISTICAL MODEL; TIME FACTOR; TREATMENT OUTCOME; YOUNG ADULT;

ADULT; BIRTH WEIGHT; CESAREAN SECTION; FEMALE; FERTILITY; GESTATIONAL AGE; HUMANS; INFANT, LOW BIRTH WEIGHT; INFANT, PREMATURE; INFERTILITY; LIVE BIRTH; LOGISTIC MODELS; MATERNAL AGE; MIDDLE AGED; ODDS RATIO; PREGNANCY; PREGNANCY COMPLICATIONS; PREMATURE BIRTH; REGISTRIES; REPRODUCTIVE TECHNIQUES, ASSISTED; RETROSPECTIVE STUDIES; RISK ASSESSMENT; RISK FACTORS; SCANDINAVIAN AND NORDIC COUNTRIES; TIME FACTORS; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84978873814     PISSN: 00150282     EISSN: 15565653     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2016.06.021     Document Type: Article

References (29)

1. 1 National Institute for Health and Welfare. Nordic perinatal statistics 2014. Helsinki, Finland. Available at: https://www.thl.fi/en/web/thlfi-en/statistics/statistics-by-topic/sexual-and-reproductive-health/parturients-deliveries-and-births/nordic-perinatal-statistics. Accessed May 14, 2016.
2. 2 Carolan, M., Maternal age ≥ 45 years and maternal and perinatal outcomes: a review of the evidence. Midwifery 29 (2013), 479–489.
3. 3 Jacobsson, B., Ladfors, L., Milsom, I., Advanced maternal age and adverse perinatal outcome. Obstet Gynecol 104 (2004), 727–733.
4. 4 Paulson, R.J., Boostanfar, R., Saadat, P., Mor, E., Tourgeman, D.E., Slater, C.C., et al. Pregnancy in the sixth decade of life: obstetric outcomes in women of advanced reproductive age. JAMA 288 (2002), 2320–2323.
5. 5 Haavaldsen, C., Sarfraz, A.A., Samuelsen, S.O., Eskild, A., The impact of maternal age on fetal death: does length of gestation matter?. Am J Obstet Gynecol 203 (2010), 554.e1–554.e8.
6. 6 Helmerhorst, F.M., Perquin, D.A., Donker, D., Keirse, M.J., Perinatal outcome of singletons and twins after assisted conception: a systematic review of controlled studies. BMJ 328 (2004), 261–266.
7. 7 Jackson, R.A., Gibson, K.A., Wu, Y.W., Croughan, M.S., Perinatal outcomes in singletons following in vitro fertilization: a meta-analysis. Obstet Gynecol 103 (2004), 551–563.
8. 8 Mc Donald, S.D., Mulla, S., Murphy, K.E., Beyene, J., Ohlsson, A., Preterm birth and low birth weight among in vitro fertilization singletons: a systematic review and meta-analyses. Eur J Obstet Gynecol Reprod Biol 146 (2009), 138–148.
9. 9 Henningsen, A.K., Romundstad, L.B., Gissler, M., Nygren, K.G., Lidegaard, O., Skjaerven, R., et al. Infant and maternal health monitoring using a combined Nordic database on ART and safety. Acta Obstet Gynecol Scand 90 (2011), 683–691.
10. 10 Marsal, K., Persson, P.H., Larsen, T., Lilja, H., Selbing, A., Sultan, B., Intrauterine growth curves based on ultrasonically estimated foetal weights. Acta Paediatr 85 (1996), 843–848.
11. 11 Cnattingius, S., Ericson, A., Gunnarskog, J., Kallen, B., A quality study of a medical birth registry. Scand J Soc Med 18 (1990), 143–148.
12. 12 Gissler, M., Louhiala, P., Hemminki, E., Nordic medical birth registers in epidemiological research. Eur J Epidemiol 13 (1997), 169–175.
13. 13 Langhoff-Roos, J., Krebs, L., Klungsoyr, K., Bjarnadottir, R.I., Kallen, K., Tapper, A.M., et al. The Nordic medical birth registers—a potential goldmine for clinical research. Acta Obstet Gynecol Scand 93 (2014), 132–137.
14. 14 National Board of Health and Welfare. The Swedish medical birth registry—a summary of content and quality. Available at: http://www.socialstyrelsen.se/publikationer//2003/2003-112-3, 2003 Accessed May 14, 2016.
15. 15 Sazonova, A., Källen, K., Thurin-Kjellberg, A., Wennerholm, U.B., Bergh, C., Factors affecting obstetric outcome of singletons born after IVF. Hum Reprod 26 (2011), 2878–2886.
16. 16 Oyelese, Y., Ananth, C.V., Placental abruption. Obstet Gynecol 108 (2006), 1005–1016.
17. 17 Sazonova, A., Källen, K., Thurin-Kjellberg, A., Wennerholm, U.B., Bergh, C., Obstetric outcome after in vitro fertilization with single or double embryo transfer. Hum Reprod 26 (2011), 442–450.
18. 18 Tandberg, A., Klungsøyr, K., Romundstad, L.B., Skjærven, R., Pre-eclampsia and assisted reproductive technologies: consequences of advanced maternal age, interbirth intervals, new partner and smoking habits. BJOG 122 (2015), 915–922.
19. 19 Pinborg, A., Wennerholm, U.B., Romundstad, L.B., Loft, A., Aittomaki, K., Söderström-Anttila, V., et al. Why do singletons conceived after assisted reproduction technology have adverse perinatal outcome? Systematic review and meta-analysis. Hum Reprod Update 19 (2013), 87–104.
20. 20 Romundstad, L.B., Romundstad, P.R., Sunde, A., von Düring, V., Skjaerven, R., Gunnell, D., et al. Effects of technology or maternal factors on perinatal outcome after assisted fertilisation: a population-based cohort study. Lancet 372 (2008), 737–743.
21. 21 Henningsen, A.K., Pinborg, A., Lidegaard, Ø., Vestergaard, C., Forman, J.L., Andersen, A.N., Perinatal outcome of singleton siblings born after assisted reproductive technology and spontaneous conception: Danish national sibling-cohort study. Fertil Steril 95 (2011), 959–963.
22. 22 Gibbons, W.E., Cedars, M., Ness, R.B., Society for Assisted Reproductive Technologies Writing Group. Toward understanding obstetrical outcome in advanced assisted reproduction: varying sperm, oocyte, and uterine source and diagnosis. Fertil Steril 95 (2011), 1645–1649.e1.
23. 23 Malchau, S.S., Loft, A., Larsen, E.C., Aaris Henningsen, A.K., Rasmussen, S., Andersen, A.N., et al. Perinatal outcomes in 375 children born after oocyte donation: a Danish national cohort study. Fertil Steril 99 (2013), 1637–1643.
24. 24 van der Hoorn, M.L., Lashley, E.E., Bianchi, D.W., Claas, F.H., Schonkeren, C.M., Scherjon, S.A., Clinical and immunologic aspects of egg donation pregnancies: a systematic review. Hum Reprod Update 16 (2010), 704–712.
25. 25 Pelkonen, S., Koivunen, R., Gissler, M., Nuojua-Huttunen, S., Suikkari, A.M., Hyden-Granskog, C., et al. Perinatal outcome of children born after frozen and fresh embryo transfer: the Finnish cohort study 1995–2006. Hum Reprod 25 (2010), 914–923.
26. 26 Pinborg, A., Henningsen, A.A., Loft, A., Malchau, S.S., Forman, J., Andersen, A.N., Large baby syndrome in singletons born after frozen embryo transfer (FET): is it due to maternal factors or the cryotechnique?. Hum Reprod 29 (2014), 618–627.
27. 27 Wennerholm, U.B., Henningsen, A.K., Romundstad, L.B., Bergh, C., Pinborg, A., Skjaerven, R., et al. Perinatal outcomes of children born after frozen-thawed embryo transfer: a Nordic cohort study from the Conartas group. Hum Reprod 28 (2013), 2545–2553.
28. 28 Xiong, X., Dickey, R.P., Pridjian, G., Buekens, P., Maternal age and preterm births in singleton and twin pregnancies conceived by in vitro fertilisation in the United States. Paediatr Perinat Epidemiol 29 (2015), 22–30.
29. 29 Rothman, K.J., No adjustments are needed for multiple comparisons. Epidemiology 1 (1990), 43–46.