Changes in tight junction protein expression in intrinsic aging and photoaging in human skin in vivo

Journal of Dermatological Science

Volumn 84, Issue 1, 2016, Pages 99-101

  Jin, Seon Pil ^a,b   Han, Sang Bum ^b   Kim, Yeon Kyung ^b   Park, Elizabeth Eunkyung ^b,c   Doh, Eun Jin ^a   Kim, Kyu Han ^a,b   Lee, Dong Hun ^a,b   Chung, Jin Ho ^a,b  

^a Seoul National University College of Medicine   (South Korea)

^b Seoul National University   (South Korea)

^c WEILL CORNELL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLAUDIN 1; MESSENGER RNA; OCCLUDIN; PROTEIN ZO1; TIGHT JUNCTION PROTEIN; CLDN1 PROTEIN, HUMAN; OCLN PROTEIN, HUMAN; TJP1 PROTEIN, HUMAN;

ADULT; AGE DISTRIBUTION; AGED; AGING; CONTROLLED STUDY; CUTANEOUS PARAMETERS; DOWN REGULATION; ENDOTHELIUM CELL; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; INTRINSIC AGING; LETTER; PHOTOAGING; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; SKIN; STRATUM CORNEUM; SUPRABASAL LAYER; ULTRAVIOLET RADIATION; WESTERN BLOTTING; EPIDERMIS; METABOLISM; PATHOLOGY; SKIN DISEASE; TIGHT JUNCTION; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; AGING; CLAUDIN-1; EPIDERMIS; GENE EXPRESSION REGULATION; HUMANS; OCCLUDIN; SKIN; SKIN AGING; SKIN DISEASES; TIGHT JUNCTIONS; ULTRAVIOLET RAYS; ZONULA OCCLUDENS-1 PROTEIN;

EID: 84978871016     PISSN: 09231811     EISSN: 1873569X     Source Type: Journal    
DOI: 10.1016/j.jdermsci.2016.07.002     Document Type: Letter

References (10)

1. Svoboda, M., Bilkova, Z., Muthny, T., Could tight junctions regulate the barrier function of the aged skin?. J. Dermatol. Sci. 81 (2015), 147–152.
2. Kubo, A., Nagao, K., Amagai, M., Epidermal barrier dysfunction and cutaneous sensitization in atopic diseases. J. Clin. Invest. 122 (2012), 440–447.
3. Sumigray, K.D., Lechler, T., Cell adhesion in epidermal development and barrier formation. Curr. Top. Dev. Biol. 112 (2015), 383–414.
4. Sugawara, T., Iwamoto, N., Akashi, M., Kojima, T., Hisatsune, J., Sugai, M., et al. Tight junction dysfunction in the stratum granulosum leads to aberrant stratum corneum barrier function in claudin-1-deficient mice. J. Dermatol. Sci. 70 (2013), 12–18.
5. Hadj-Rabia, S., Baala, L., Vabres, P., Hamel-Teillac, D., Jacquemin, E., Fabre, M., et al. Claudin-1 gene mutations in neonatal sclerosing cholangitis associated with ichthyosis: a tight junction disease. Gastroenterology 127 (2004), 1386–1390.
6. Takahashi, M., Tezuka, T., The content of free amino acids in the stratum corneum is increased in senile xerosis. Arch. Dermatol. Res. 295 (2004), 448–452.
7. Yamamoto, T., Kurasawa, M., Hattori, T., Maeda, T., Nakano, H., Sasaki, H., Relationship between expression of tight junction-related molecules and perturbed epidermal barrier function in UVB-irradiated hairless mice. Arch. Dermatol. Res. 300 (2008), 61–68.
8. Yuki, T., Hachiya, A., Kusaka, A., Sriwiriyanont, P., Visscher, M.O., Morita, K., et al. Characterization of tight junctions and their disruption by UVB in human epidermis and cultured keratinocytes. J. Invest. Dermatol. 131 (2011), 744–752.
9. Hung, C.F., Fang, C.L., Al-Suwayeh, S.A., Yang, S.Y., Fang, J.Y., Evaluation of drug and sunscreen permeation via skin irradiated with UVA and UVB: comparisons of normal skin and chronologically aged skin. J. Dermatol. Sci. 68 (2012), 135–148.
10. Rachow, S., Zorn-Kruppa, M., Ohnemus, U., Kirschner, N., Vidal-y-Sy, S., von den Driesch, P., et al. Occludin is involved in adhesion, apoptosis, differentiation and Ca2+-homeostasis of human keratinocytes: implications for tumorigenesis. PLoS One, 2013, e55116.