Impacts of preeclampsia on the brain of the offspring;Impactos da pré-eclâmpsia no cérebro de nascituros

Revista Brasileira de Ginecologia e Obstetricia

Volumn 38, Issue 8, 2016, Pages 416-422

  Dang, Frances ^a   Croy, B Anne ^a   Stroman, Patrick W ^b   Figueiró Filho, Ernesto Antonio ^a,c  

^a QUEEN S UNIVERSITY   (Canada)

^b QUEEN S UNIVERSITY   (Canada)

^c FEDERAL UNIVERSITY OF MATO GROSSO DO SUL   (Brazil)

Author keywords

Cognitive development; Fetal brain; MRI; PGF; Preeclampsia

Indexed keywords

PLACENTAL GROWTH FACTOR;

BRAIN; CHILD; FEMALE; GROWTH, DEVELOPMENT AND AGING; HUMAN; MALE; PHYSIOLOGY; PREECLAMPSIA; PREGNANCY;

BRAIN; CHILD; FEMALE; HUMANS; MALE; PLACENTA GROWTH FACTOR; PRE-ECLAMPSIA; PREGNANCY;

EID: 84978764786     PISSN: 01007203     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0036-1584515     Document Type: Review

References (57)

1. American College of Obstetricians and Gynecologists; Task Force on Hypertension in Pregnancy. Hypertension in pregnancy. Report of the American College of Obstetricians and Gynecologists’ Task Force on Hypertension in Pregnancy. Obstet Gynecol 2013; 122(5):1122-1131
2. Duley L. The global impact of pre-eclampsia and eclampsia. Semin Perinatol 2009;33(3):130-137
3. Lo JO, Mission JF, Caughey AB. Hypertensive disease of pregnancy and maternal mortality. Curr Opin Obstet Gynecol 2013;25(2): 124-132
4. Tranquilli AL, Dekker G, Magee L, et al. The classification, diagnosis and management of the hypertensive disorders of pregnancy: A revised statement from the ISSHP. Pregnancy Hypertens 2014; 4(2):97-104
5. Ahmed A, Ramma W. Unravelling the theories of pre-eclampsia: are the protective pathways the new paradigm? Br J Pharmacol 2015;172(6):1574-1586
6. Torry DS, Wang HS, Wang TH, Caudle MR, Torry RJ. Preeclampsia is associated with reduced serum levels of placenta growth factor. Am J Obstet Gynecol 1998;179(6 Pt 1):1539-1544
7. Levine RJ, Maynard SE, Qian C, et al. Circulating angiogenic factors and the risk of preeclampsia. N Engl J Med 2004;350(7):672-683
8. Lykke JA, Langhoff-Roos J, Sibai BM, Funai EF, Triche EW, Paidas MJ. Hypertensive pregnancy disorders and subsequent cardiovascular morbidity and type 2 diabetes mellitus in the mother. Hypertension 2009;53(6):944-951
9. Melchiorre K, Sutherland GR, Liberati M, Thilaganathan B. Preeclampsia is associated with persistent postpartum cardiovascular impairment. Hypertension 2011;58(4):709-715
10. Mongraw-Chaffin ML, Cirillo PM, Cohn BA. Preeclampsia and cardiovascular disease death: prospective evidence fromthe child health and development studies cohort. Hypertension 2010; 56(1):166-171
11. Magnussen EB, Vatten LJ, Myklestad K, Salvesen KÅ, Romundstad PR. Cardiovascular risk factors prior to conception and the length of pregnancy: population-based cohort study. Am J Obstet Gynecol 2011;204(6):526.e1-526.e8
12. Magnussen EB, Vatten LJ, Lund-Nilsen TI, Salvesen KA, Davey Smith G, Romundstad PR. Prepregnancy cardiovascular risk factors as predictors of pre-eclampsia: population based cohort study. BMJ 2007;335(7627):978
13. Smith GN, Walker MC, Liu A, et al; Pre-Eclampsia New Emerging Team (PE-NET). A history of preeclampsia identifies women who have underlying cardiovascular risk factors. Am J Obstet Gynecol 2009;200(1):58.e1-58.e8
14. Rich-Edwards JW, Fraser A, Lawlor DA, Catov JM. Pregnancy characteristics and women’s future cardiovascular health: an underused opportunity to improve women’s health? Epidemiol Rev 2014;36:57-70
15. Sattar N, Greer IA. Pregnancy complications and maternal cardiovascular risk: opportunities for intervention and screening? BMJ 2002;325(7356):157-160
16. Irgens HU, Reisaeter L, Irgens LM, Lie RT. Long term mortality of mothers and fathers after pre-eclampsia: population based cohort study. BMJ 2001;323(7323):1213-1217
17. Bushnell C, Chireau M. Preeclampsia and Stroke: Risks during and after Pregnancy. Stroke Res Treat 2011;2011:858134
18. Rätsep MT, Paolozza A, Hickman AF, et al. Brain structural and vascular anatomy is altered in offspring of pre-eclamptic pregnancies: a pilot study. AJNR Am J Neuroradiol 2015; [Epub ahead of print]
19. Rätsep MT, Hickman AF, Maser B, et al. Impact of preeclampsia on cognitive function in the offspring. Behav Brain Res 2016; 302:175-181
20. Lazdam M, de la Horra A, Pitcher A, et al. Elevated blood pressure in offspring born premature to hypertensive pregnancy: is endothelial dysfunction the underlying vascular mechanism? Hypertension 2010;56(1):159-165
21. Seidman DS, Laor A, Gale R, Stevenson DK, Mashiach S, Danon YL. Pre-eclampsia and offspring’s blood pressure, cognitive ability and physical development at 17-years-of-age. Br J Obstet Gynaecol 1991;98(10):1009-1014
22. Tenhola S, Rahiala E, Martikainen A, Halonen P, Voutilainen R. Blood pressure, serum lipids, fasting insulin, and adrenal hormones in 12-year-old children born with maternal preeclampsia. J Clin Endocrinol Metab 2003;88(3):1217-1222
23. Tuovinen S, Räikkönen K, Pesonen AK, et al. Hypertensive disorders in pregnancy and risk of severe mental disorders in the offspring in adulthood: the Helsinki Birth Cohort Study. J Psychiatr Res 2012;46(3):303-310
24. Tuovinen S, Räikkönen K, Kajantie E, et al. Depressive symptoms in adulthood and intrauterine exposure to pre-eclampsia: the Helsinki Birth Cohort Study. BJOG 2010;117(10):1236-1242
25. Tuovinen S, Eriksson JG, Kajantie E, et al. Maternal hypertensive disorders in pregnancy and self-reported cognitive impairment of the offspring 70 years later: the Helsinki Birth Cohort Study. Am J Obstet Gynecol 2013;208(3):200.e1-200.e9
26. Kajantie E, Eriksson JG, Osmond C, Thornburg K, Barker DJ. Preeclampsia is associated with increased risk of stroke in the adult offspring: the Helsinki birth cohort study. Stroke 2009;40(4): 1176-1180
27. Davis EF, Lazdam M, Lewandowski AJ, et al. Cardiovascular risk factors in children and young adults born to preeclamptic pregnancies: a systematic review. Pediatrics 2012;129(6): e1552-e1561
28. Tuovinen S, Eriksson JG, Kajantie E, Räikkönen K. Maternal hypertensive pregnancy disorders and cognitive functioning of the offspring: a systematic review. J Am Soc Hypertens 2014;8-(11):832-47.e1
29. Whitehouse AJ, Robinson M, Newnham JP, Pennell CE. Do hypertensive diseases of pregnancy disrupt neurocognitive development in offspring? Paediatr Perinat Epidemiol 2012;26(2): 101-108
30. Many A, Fattal A, Leitner Y, Kupferminc MJ, Harel S, Jaffa A. Neurodevelopmental and cognitive assessment of children born growth restricted to mothers with and without preeclampsia. Hypertens Pregnancy 2003;22(1):25-29
31. Spinillo A, Iasci A, Capuzzo E, Egbe TO, Colonna L, Fazzi E. Two-year infant neurodevelopmental outcome after expectant management and indicated preterm delivery in hypertensive pregnancies. Acta Obstet Gynecol Scand 1994;73(8):625-629
32. Morsing E, Maršál K. Pre-eclampsia-an additional risk factor for cognitive impairment at school age after intrauterine growth restriction and very preterm birth. Early Hum Dev 2014;90(2): 99-101
33. Carmeliet P, Ferreira V, Breier G, et al. Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature 1996;380(6573):435-439
34. Charnock-Jones DS. Soluble flt-1 and the angiopoietins in the development and regulation of placental vasculature. J Anat 2002; 200(6):607-615
35. Lambert-Messerlian G, Eklund EE, Chien EK, et al. Use of first or second trimester serum markers, or both, to predict preeclampsia. Pregnancy Hypertens 2014;4(4):271-278
36. Powers RW, Roberts JM, Plymire DA, et al. Low placental growth factor across pregnancy identifies a subset of women with preterm preeclampsia: type 1 versus type 2 preeclampsia? Hypertension 2012;60(1):239-246
37. Staff AC, Benton SJ, von Dadelszen P, et al. Redefining preeclampsia using placenta-derived biomarkers. Hypertension 2013;61(5): 932-942
38. Zeisler H, Llurba E, Chantraine F, et al. Predictive value of the sFlt-1:PIGF ratio inwomen with suspected preeclampsia. N Engl J Med 2016;374(1):13-22
39. Brennan LJ, Morton JS, Davidge ST. Vascular dysfunction in preeclampsia. Microcirculation 2014;21(1):4-14
40. Rätsep MT, Carmeliet P, Adams MA, Croy BA. Impact of placental growth factor deficiency on early mouse implant site angiogenesis. Placenta 2014;35(9):772-775
41. Aasa KL, Zavan B, Luna RL, et al. Placental growth factor influences maternal cardiovascular adaptation to pregnancy in mice. Biol Reprod 2015;92(2):44
42. Rätsep MT, Hickman AF, Croy BA. The Elsevier trophoblast research award lecture: Impacts of placental growth factor and preeclampsia on brain development, behaviour, and cognition. Placenta 2016; [Epub ahead of print]
43. Quaegebeur A, Lange C, Carmeliet P. The neurovascular link in health and disease: molecular mechanisms and therapeutic implications. Neuron 2011;71(3):406-424
44. Tau GZ, Peterson BS. Normal development of brain circuits. Neuropsychopharmacology 2010;35(1):147-168
45. Menshawi K, Mohr JP, Gutierrez J. A functional perspective on the embryology and anatomy of the cerebral blood supply. J Stroke 2015;17(2):144-158
46. Kathuria S, Gregg L, Chen J, Gandhi D. Normal cerebral arterial development and variations. Semin Ultrasound CT MR 2011; 32(3):242-251
47. Lenroot RK, Giedd JN. Brain development in children and adolescents: insights from anatomical magnetic resonance imaging. Neurosci Biobehav Rev 2006;30(6):718-729
48. Baker J, Workman M, Bedrick E, Frey MA, Hurtado M, Pearson O. Brains versus brawn: an empirical test of Barker’s brain sparing model. Am J Hum Biol 2010;22(2):206-215
49. Rätsep MT, Felker AM, Kay VR, Tolusso L, Hofmann AP, Croy BA. Uterine natural killer cells: supervisors of vasculature construction in early decidua basalis. Reproduction 2015;149(2):R91-R102
50. Luna RL, Kay VR, Rätsep MT, et al. Placental growth factor deficiency is associated with impaired cerebral vascular development in mice. Mol Hum Reprod 2016;22(2):130-142
51. Chaballe L, Close P, SempelsM, et al. Involvement of placental growth factor in Wallerian degeneration. Glia 2011;59(3):379-396
52. VanOverbeeke JJ, Hillen B, Tulleken CA. A comparative study of the circle of Willis in fetal and adult life. The configuration of the posterior bifurcation of the posterior communicating artery. J Anat 1991;176:45-54
53. Romero R, Nien JK, Espinoza J, et al. A longitudinal study of angiogenic (placental growth factor) and anti-angiogenic (soluble endoglin and soluble vascular endothelial growth factor receptor-1) factors in normal pregnancy and patients destined to develop preeclampsia and deliver a small for gestational age neonate. J Matern Fetal Neonatal Med 2008;21(1):9-23
54. Cetin I, Mazzocco MI, Giardini V, et al. PlGF in a clinical setting of pregnancies at risk of preeclampsia and/or intrauterine growth restriction. J Matern Fetal Neonatal Med 2016;19:1-6[Epub ahead of print]
55. Paolozza A, Treit S, Beaulieu C, Reynolds JN. Response inhibition deficits in children with Fetal Alcohol Spectrum Disorder: relationship between diffusion tensor imaging of the corpus callosum and eye movement control. Neuroimage Clin 2014; 5:53-61
56. Paolozza A, Munn R, Munoz DP, Reynolds JN. An in-depth analysis of saccade metrics in children with fetal alcohol spectrum disorder (FASD). Int J Dev Neurosci 2015;47(A):57-58
57. Paolozza A, Munn R, Munoz DP, Reynolds JN. Eye movements reveal sexually dimorphic deficits in children with fetal alcohol spectrum disorder. Front Neurosci 2015;9:76