Correlation of optical coherence tomography and autofluorescence in the outer retina and choroid of patients with choroideremia

Investigative Ophthalmology and Visual Science

Volumn 57, Issue 8, 2016, Pages 3674-3684

  Xue, Kanmin ^a   Oldani, Marta ^a   Jolly, Jasleen K ^a   Edwards, Thomas L ^a   Groppe, Markus ^a   Downes, Susan M ^a   Maclaren, Robert E ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Autofluorescence; Choroideremia; Optical coherence tomography

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; AUTOFLUORESCENCE IMAGING; B SCAN; CHOROID; CHOROIDEREMIA; CLINICAL ARTICLE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CORRELATION ANALYSIS; ELLIPSOID ZONE; GENE THERAPY; HUMAN; MALE; OPTICAL COHERENCE TOMOGRAPHY; OUTER RETINAL TUBULATION; PHOTORECEPTOR; PIGMENT EPITHELIUM; PRIORITY JOURNAL; RETINA DISEASE; RETINAL ROD OUTER SEGMENT; RETROSPECTIVE STUDY; SCANNING LASER OPHTHALMOSCOPY; SUBFOVEAL CHOROIDAL THICKNESS; VISUAL SYSTEM PARAMETERS; YOUNG ADULT; CLINICAL TRIAL; DIAGNOSTIC IMAGING; FEMALE; FLUORESCENCE IMAGING; MIDDLE AGED; PROCEDURES; RETINA;

ADOLESCENT; ADULT; AGED; CHOROID; CHOROIDEREMIA; FEMALE; HUMANS; MALE; MIDDLE AGED; OPTICAL IMAGING; RETINA; RETROSPECTIVE STUDIES; TOMOGRAPHY, OPTICAL COHERENCE; YOUNG ADULT;

EID: 84978543472     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.15-18364     Document Type: Article

References (23)

1. Jolly JK, Edwards TL, Moules J, Groppe M, Downes SM, MacLaren RE. A qualitative and quantitative assessment of fundus autofluorescence patterns in patients with choroideremia. Invest Ophthalmol Vis Sci. In press.
2. MacLaren RE, Groppe M, Barnard AR, et al. Retinal gene therapy in patients with choroideremia: initial findings from a phase 1/2 clinical trial. Lancet. 2014;83:1129–1137.
3. Spaide RF, Curcio CA. Anatomical correlates to the bands seen in the outer retina by optical coherence tomography: literature review and model. Retina. 2011;31:1609–1619.
4. Curcio CA, Sloan KR, Kalina RE, et al. Human photoreceptor topography. J Comp Neurol. 1990;292:497–523.
5. Morgan JI, Han G, Klinman E, et al. High-resolution adaptive optics retinal imaging of cellular structure in choroideremia. Invest Ophthalmol Vis Sci. 2014;55:6381–6397.
6. Zweifel SA, Engelbert M, Laud K, et al. Outer retinal tubulation: a novel optical coherence tomography finding. Arch Ophthalmol. 2009;127:1596–1602.
7. Tolmachova T, Anders R, Abrink M, et al. Independent degeneration of photoreceptors and retinal pigment epithelium in conditional knockout mouse models of choroideremia. J Clin Invest. 2006;116:386–394.
8. Tolmachova T, Wavre-Shapton ST, Barnard AR, et al. Retinal pigment epithelium defects accelerate photoreceptor degeneration in cell type-specific knockout mouse models of choroideremia. Invest Ophthalmol Vis Sci. 2010;51:4913–4920.
9. Roorda A, Zhang Y, Duncan JL. High-resolution in vivo imaging of the RPE mosaic in eyes with retinal disease. Invest Ophthalmol Vis Sci. 2007;48:2297–2303.
10. Barteselli G, Bartsch DU, Viola F, et al. Accuracy of the Heidelberg Spectralis in the alignment between near-infrared image and tomographic scan in a model eye: a multicenter study. Am J Ophthalmol. 2013;156:588–592.
11. Jacobson SG, Cideciyan AV, Sumaroka A, et al. Remodelling of the human retina in choroideremia: rab escort protein 1 (REP- 1) mutations. Invest Ophthalmol Vis Sci. 2006;47:4113–4120.
12. Lazow MA, Hood DC, Ramachandran R, et al. Transition zones between healthy and diseased retina in choroideremia (CHM) and Stargardt disease (STGD) as compared to retinitis pigmentosa (RP). Invest Ophthalmol Vis Sci. 2011;52:9581–9590.
13. Syed N, Smith JE, John SK, et al. Evaluation of retinal photoreceptors and pigment epithelium in a female carrier of choroideremia. Ophthalmology. 2001;108:711–720.
14. Laviers H, Zambarakji H. Enhanced depth imaging-OCT of the choroid: a review of the current literature. Graefes Arch Clin Exp Ophthalmol. 2014;252:1871–1883.
15. Sigler EJ, Randolph JC. Comparison of macular choroidal thickness among patients older than age 65 with early atrophic age-related macular degeneration and normals. Invest Ophthalmol Vis Sci. 2013;54:6307–6313.
16. Wolff B, Matet A, Vasseur V, et al. En face OCT imaging for the diagnosis of outer retinal tubulations in age-related macular degeneration. J Ophthalmol. 2012;2012:542417.
17. Sergouniotis PI, Davidson AE, Lenassi E, et al. Retinal structure, function, and molecular pathologic features in gyrate atrophy. Ophthalmology. 2012;119:596–605.
18. Gallego-Pinazo R, Marsiglia M, Mrejen S, et al. Outer retinal tubulations in chronic central serous chorioretinopathy. Graefes Arch Clin Exp Ophthalmol. 2013;251:1655–1656.
19. Raja MS, Goldsmith C, Burton BJ. Outer retinal tubulations in maternally inherited diabetes and deafness (MIDD)-associated macular dystrophy. Graefes Arch Clin Exp Ophthalmol. 2013; 251:2265–2267.
20. Goldberg NR, Greenberg JP, Laud K, et al. Outer retinal tubulation in degenerative retinal disorders. Retina. 2013;33: 1871–1876.
21. Mateo-Montoya A, Wolff B, Sahel JA, et al. Outer retinal tubulations in serpinginous choroiditis. Graefes Arch Clin Exp Ophthalmol. 2013;251:2657–2658.
22. Schaal KB, Freund KB, Litts KM, et al. Outer retinal tubulation in advanced age-related macular degeneration: optical coherence tomographic findings correspond to histology. Retina. 2015;35:1339–1350.
23. Wolff B, Maftouhi MQE, Mateo-Montoya A, et al. Outer retinal cysts in age-related macular degeneration. Acta Ophthalmologica. 2011;89:496–499.