Identification and quantification of bleomycin in serum and tumor tissue by liquid chromatography coupled to high resolution mass spectrometry

Talanta

Volumn 160, Issue , 2016, Pages 164-171

  Kosjek, Tina ^a   Krajnc, Anja ^a   Gornik, Tjasa ^a   Zigon, Dusan ^a   Groselj, Ales ^b   Sersa, Gregor ^c   Cemazar, Maja ^c  

^a JO EF STEFAN INSTITUTE   (Slovenia)

^b UNIVERSITY MEDICAL CENTRE LJUBLJANA   (Slovenia)

^c INSTITUTE OF ONCOLOGY   (Slovenia)

Author keywords

Bleomycin; Copper complex; High resolution mass spectrometry; Liquid chromatography; Serum; Tumor

Indexed keywords

BODY FLUIDS; CHELATION; COMPOSTING; COPPER COMPOUNDS; HIGH PRESSURE LIQUID CHROMATOGRAPHY; HISTOLOGY; ION SOURCES; ISOTOPES; LIQUID CHROMATOGRAPHY; LIQUIDS; MASS SPECTROMETRY; METAL COMPLEXES; METALS; PHARMACOKINETICS; TISSUE ENGINEERING; TUMORS;

BLEOMYCINS; COPPER COMPLEXES; ELECTROSPRAY ION SOURCES; HIGH RESOLUTION MASS SPECTROMETRY; PHARMACOKINETIC PARAMETERS; PHARMACOKINETIC STUDIES; SELECTIVE LIQUID CHROMATOGRAPHY; SERUM;

PEPTIDES;

ANTINEOPLASTIC ANTIBIOTIC; BLEOMYCIN; COORDINATION COMPOUND; COPPER;

ANIMAL; BLOOD; C57BL MOUSE; CHEMISTRY; ELECTROSPRAY MASS SPECTROMETRY; FEMALE; HUMAN; LIQUID CHROMATOGRAPHY; METABOLISM; NEOPLASM;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BLEOMYCIN; CHROMATOGRAPHY, LIQUID; COORDINATION COMPLEXES; COPPER; FEMALE; HUMANS; MICE, INBRED C57BL; NEOPLASMS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 84978488598     PISSN: 00399140     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.talanta.2016.06.062     Document Type: Article

References (17)

1. [1] Claussen, C.A., Long, E.C., Nucleic acid recognition by metal complexes of bleomycin. Chem. Rev. 99 (1999), 2797–2816.
2. [2] Umezawa, H., Takita, T., The Bleomycins: Antitumor Copper-binding Antibiotics, in: Biochemistry (Series Structure and Bonding, 40). 1980, Springer Berlin Heidelberg, 73–99.
3. [3] Aszalos, A., Crawford, J., Vollmer, P., Kantor, N., Alexander, T., High-performance liquid chromatographic determination of components of bleomycin preparations. J. Pharm. Sci. 70 (1981), 878–880.
4. [4] Council of Europe. Bleomycin suphate, in: European Pharmacopoeia, 5th ed. Main volume 5.0, 2005, pp. 1114–1115.
5. [5] Shiu, G.K., Goehl, T.J., Pitlick, W.H., Rapid high-performance liquid chromatographic determination of bleomycin A2 in plasma. J. Pharm. Sci. 68 (1979), 232–234.
6. 2 in urine. J. Chromatogr. 181 (1980), 127–131.
7. [7] Broughton, A., Strong, J.E., Radioimmunoassay of bleomycin. Cancer Res. 36 (1976), 1418–1421.
8. [8] Mahdadi, R., Kenani, A., Pommery, N., Pommery, J., Hénichart, J.P., Lhermitte, M., High-performance liquid chromatography assay of bleomycin in human plasma and rat hepatocytes in culture. Cancer Chemother. Pharmacol. 28 (1991), 22–26.
9. [9] Mabeta, P., Dippenaar, N., Shelver, G., A validated HPLC method for the simultaneous determination of bleomycin A2 and B2 in human plasma. Int. J. Pharm. Biomed. Res. 3 (2012), 191–194.
10. [10] Galba, J., Veizerová, L., Piešťanský, J., Mego, M., Novotný, L., Dokupilová, S., Maráková, K., Havránek, E., Mikuš, P., HPLC-QTOF-MS method for identification and determination of Bleomycin A2 and B2 fractions. J. Liq. Chromatogr. Relat. Technol. 38 (2015), 294–302.
11. [11] Yin, B.-C., Wu, D., Ye, B.-C., Sensitive DNA-based electrochemical strategy for trace bleomycin detection. Anal. Chem. 82 (2010), 8272–8277.
12. [12] Campana, L.G., Clover, A.J.P., Valpione, S., Quaglino, P., Gehl, J., Kunte, C., Snoj, M., Cemazar, M., Rossi, C.R., Miklavcic, D., Sersa, G., Recommendations for improving the quality of reporting clinical electrochemotherapy studies based on qualitative systematic review. Radiol. Oncol 50 (2016), 1–13.
13. [13] Domenge, C., Orlowski, S., Luboinski, B., De Baere, T., Schwaab, G., Belehradek, J.Jr, Mir, L.M., Antitumor electrochemotherapy: new advances in the clinical protocol. Cancer 77 (1996), 956–963.
14. [14] Food and Drug Administration: “Bioanalytical Method Validation” (Guidance for Industry). 〈http://www.fda.gov/downloads/drugs/guidancecomplianceregulatoryinformation/guidances/ucm070107.pdf〉. Accessed Dec 2015.
15. [15] Kruve, A., Rebane, R., Kipper, K., Oldekop, M.-L., Evard, H., Herodes, K., Ravio, P., Leito, I., Tutorial review on validation of liquid chromatography–mass spectrometry methods: Part II. Anal. Chim. Acta 870 (2015), 8–28.
16. [16] Nunn, A.D., The relative stability of bleomycin metal complexes to metal exchange. Eur. J. Nucl. Med. 2 (1977), 53–57.
17. [17] “AccuTOF” JMS-T100LC High Performance LC-TOFMS. 〈http://www.jeolusa.com/DesktopModules/Bring2mind/DMX/Download.aspx?Command=Core_Download&EntryId=170&PortalId=2&TableId=337〉. (Accessed 09.12.15).