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Volumn 76, Issue 14, 2016, Pages 4283-4292

MFG-E8 drives melanoma growth by stimulating mesenchymal stromal cell-induced angiogenesis and M2 polarization of tumor-associated macrophages

Author keywords

[No Author keywords available]

Indexed keywords

CD31 ANTIGEN; CELL PROTEIN; ET 1 PROTEIN; LACTADHERIN; UNCLASSIFIED DRUG; VASCULOTROPIN; ENDOTHELIN 1; MEMBRANE ANTIGEN; MFGE8 PROTEIN, MOUSE; MILK PROTEIN; VASCULOTROPIN A;

EID: 84978370504     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-15-2812     Document Type: Article
Times cited : (72)

References (44)
  • 3
    • 42149189474 scopus 로고    scopus 로고
    • Mesenchymal stem cells are recruited into wounded skin and contribute to wound repair by transdifferentiation into multiple skin cell type
    • Sasaki M, Abe R, Fujita Y, Ando S, Inokuma D, Shimizu H. Mesenchymal stem cells are recruited into wounded skin and contribute to wound repair by transdifferentiation into multiple skin cell type. J Immunol 2008;180: 2581-7.
    • (2008) J Immunol , vol.180 , pp. 2581-2587
    • Sasaki, M.1    Abe, R.2    Fujita, Y.3    Ando, S.4    Inokuma, D.5    Shimizu, H.6
  • 6
    • 55049092713 scopus 로고    scopus 로고
    • In search of the in vivo identity of mesenchymal stem cells
    • da Silva Meirelles L, Caplan AI, Nardi NB. In search of the in vivo identity of mesenchymal stem cells. Stem Cells 2008;26:2287-99.
    • (2008) Stem Cells , vol.26 , pp. 2287-2299
    • Da Silva Meirelles, L.1    Caplan, A.I.2    Nardi, N.B.3
  • 7
    • 0035889146 scopus 로고    scopus 로고
    • Identification of mesenchymal stem/progenitor cells in human first-trimester fetal blood, liver, and bone marrow
    • Campagnoli C, Roberts IA, Kumar S, Bennett PR, Bellantuono I, Fisk NM. Identification of mesenchymal stem/progenitor cells in human first-trimester fetal blood, liver, and bone marrow. Blood 2001;98:2396-402.
    • (2001) Blood , vol.98 , pp. 2396-2402
    • Campagnoli, C.1    Roberts, I.A.2    Kumar, S.3    Bennett, P.R.4    Bellantuono, I.5    Fisk, N.M.6
  • 8
    • 60849136593 scopus 로고    scopus 로고
    • Mesenchymal stem cell homing: The devil is in the details
    • Karp JM, Leng Teo GS. Mesenchymal stem cell homing: the devil is in the details. Cell Stem Cell 2009;4:206-16.
    • (2009) Cell Stem Cell , vol.4 , pp. 206-216
    • Karp, J.M.1    Leng Teo, G.S.2
  • 9
    • 77249096843 scopus 로고    scopus 로고
    • Plateletderived growth factor BB mediates the tropism of human mesenchymal stem cells for malignant gliomas
    • Hata N, Shinojima N, Gumin J, Yong R, Marini F, Andreeff M, et al. Plateletderived growth factor BB mediates the tropism of human mesenchymal stem cells for malignant gliomas. Neurosurgery 2010;66:144-56.
    • (2010) Neurosurgery , vol.66 , pp. 144-156
    • Hata, N.1    Shinojima, N.2    Gumin, J.3    Yong, R.4    Marini, F.5    Andreeff, M.6
  • 10
    • 79960720038 scopus 로고    scopus 로고
    • Mesenchymal stromal cells promote tumor growth through the enhancement of neovascularization
    • Suzuki K, Sun R, Origuchi M, Kanehira M, Takahata T, Itoh J, et al. Mesenchymal stromal cells promote tumor growth through the enhancement of neovascularization. Mol Med 2011;17:579-87.
    • (2011) Mol Med , vol.17 , pp. 579-587
    • Suzuki, K.1    Sun, R.2    Origuchi, M.3    Kanehira, M.4    Takahata, T.5    Itoh, J.6
  • 11
    • 80054938093 scopus 로고    scopus 로고
    • Immunosuppressive effect of bone marrow-derived mesenchymal stem cells in inflammatory microenvironment favours the growth of B16 melanoma cells
    • Han Z, Tian Z, Lv G, Zhang L, Jiang G, Sun K, et al. Immunosuppressive effect of bone marrow-derived mesenchymal stem cells in inflammatory microenvironment favours the growth of B16 melanoma cells. J Cell Mol Med 2011;15:2343-52.
    • (2011) J Cell Mol Med , vol.15 , pp. 2343-2352
    • Han, Z.1    Tian, Z.2    Lv, G.3    Zhang, L.4    Jiang, G.5    Sun, K.6
  • 12
    • 34948896045 scopus 로고    scopus 로고
    • Mesenchymal stem cells within tumour stroma promote breast cancer metastasis
    • Karnoub AE, Dash AB, Vo AP, Sullivan A, Brooks MW, Bell GW, et al. Mesenchymal stem cells within tumour stroma promote breast cancer metastasis. Nature 2007;449:557-63.
    • (2007) Nature , vol.449 , pp. 557-563
    • Karnoub, A.E.1    Dash, A.B.2    Vo, A.P.3    Sullivan, A.4    Brooks, M.W.5    Bell, G.W.6
  • 13
    • 58149235124 scopus 로고    scopus 로고
    • Bone marrow multipotent mesenchymal stroma cells act as pericyte-like migratory vehicles in experimental gliomas
    • Bexell D, Gunnarsson S, Tormin A, Darabi A, Gisselsson D, Roybon L, et al. Bone marrow multipotent mesenchymal stroma cells act as pericyte-like migratory vehicles in experimental gliomas. Mol Ther 2009;17:183-90.
    • (2009) Mol Ther , vol.17 , pp. 183-190
    • Bexell, D.1    Gunnarsson, S.2    Tormin, A.3    Darabi, A.4    Gisselsson, D.5    Roybon, L.6
  • 14
    • 67650227686 scopus 로고    scopus 로고
    • Robust functional vascular network formation in vivo by cooperation of adipose progenitor and endothelial cells
    • Traktuev DO, Prater DN, Merfeld-Clauss S, Sanjeevaiah AR, Saadatzadeh MR, Murphy M, et al. Robust functional vascular network formation in vivo by cooperation of adipose progenitor and endothelial cells. Circ Res 2009;104:1410-20.
    • (2009) Circ Res , vol.104 , pp. 1410-1420
    • Traktuev, D.O.1    Prater, D.N.2    Merfeld-Clauss, S.3    Sanjeevaiah, A.R.4    Saadatzadeh, M.R.5    Murphy, M.6
  • 15
    • 84944474775 scopus 로고    scopus 로고
    • Zoledronic acid prevents the tumor-promoting effects of mesenchymal stem cells via MCP-1 dependent recruitment of macrophages
    • Jia XH, Du Y, Mao D, Wang ZL, He ZQ, Qiu JD, et al. Zoledronic acid prevents the tumor-promoting effects of mesenchymal stem cells via MCP-1 dependent recruitment of macrophages. Oncotarget 2015;6:26018-28.
    • (2015) Oncotarget , vol.6 , pp. 26018-26028
    • Jia, X.H.1    Du, Y.2    Mao, D.3    Wang, Z.L.4    He, Z.Q.5    Qiu, J.D.6
  • 16
    • 84870933589 scopus 로고    scopus 로고
    • CCR2-dependent recruitment of macrophages by tumor-educated mesenchymal stromal cells promotes tumor development and is mimicked by TNFalpha
    • Ren G, Zhao X, Wang Y, Zhang X, Chen X, Xu C, et al. CCR2-dependent recruitment of macrophages by tumor-educated mesenchymal stromal cells promotes tumor development and is mimicked by TNFalpha. Cell Stem Cell 2012;11:812-24.
    • (2012) Cell Stem Cell , vol.11 , pp. 812-824
    • Ren, G.1    Zhao, X.2    Wang, Y.3    Zhang, X.4    Chen, X.5    Xu, C.6
  • 17
    • 0025087144 scopus 로고
    • cDNA cloning of a mouse mammary epithelial cell surface protein reveals the existence of epidermal growth factor-like domains linked to factor VIII-like sequences
    • Stubbs JD, Lekutis C, Singer KL, Bui A, Yuzuki D, Srinivasan U, et al. cDNA cloning of a mouse mammary epithelial cell surface protein reveals the existence of epidermal growth factor-like domains linked to factor VIII-like sequences. Proc Natl Acad Sci U S A 1990;87:8417-21.
    • (1990) Proc Natl Acad Sci U S A , vol.87 , pp. 8417-8421
    • Stubbs, J.D.1    Lekutis, C.2    Singer, K.L.3    Bui, A.4    Yuzuki, D.5    Srinivasan, U.6
  • 18
    • 0030749214 scopus 로고    scopus 로고
    • Lactadherin (formerly BA46), a membrane-associated glycoprotein expressed in human milk and breast carcinomas, promotes Arg-Gly-Asp (RGD)-dependent cell adhesion
    • Taylor MR, Couto JR, Scallan CD, Ceriani RL, Peterson JA. Lactadherin (formerly BA46), a membrane-associated glycoprotein expressed in human milk and breast carcinomas, promotes Arg-Gly-Asp (RGD)-dependent cell adhesion. DNA Cell Biol 1997;16:861-9.
    • (1997) DNA Cell Biol , vol.16 , pp. 861-869
    • Taylor, M.R.1    Couto, J.R.2    Scallan, C.D.3    Ceriani, R.L.4    Peterson, J.A.5
  • 20
    • 7744225985 scopus 로고    scopus 로고
    • Lactadherin binds selectively to membranes containing phosphatidyl-L-serine and increased curvature
    • Shi J, Heegaard CW, Rasmussen JT, Gilbert GE. Lactadherin binds selectively to membranes containing phosphatidyl-L-serine and increased curvature. Biochim Biophys Acta 2004;1667:82-90
    • (2004) Biochim Biophys Acta , vol.1667 , pp. 82-90
    • Shi, J.1    Heegaard, C.W.2    Rasmussen, J.T.3    Gilbert, G.E.4
  • 21
    • 4344715014 scopus 로고    scopus 로고
    • Masking of phosphatidylserine inhibits apoptotic cell engulfment and induces autoantibody production in mice
    • Asano K, Miwa M, Miwa K, Hanayama R, Nagase H, Nagata S, et al. Masking of phosphatidylserine inhibits apoptotic cell engulfment and induces autoantibody production in mice. J Exp Med 2004;200:459-67.
    • (2004) J Exp Med , vol.200 , pp. 459-467
    • Asano, K.1    Miwa, M.2    Miwa, K.3    Hanayama, R.4    Nagase, H.5    Nagata, S.6
  • 23
    • 34547131311 scopus 로고    scopus 로고
    • MFG-E8/lactadherin promotes tumor growth in an angiogenesis-dependent transgenic mouse model of multistage carcinogenesis
    • Neutzner M, Lopez T, Feng X, Bergmann-Leitner ES, Leitner WW, Udey MC. MFG-E8/lactadherin promotes tumor growth in an angiogenesis-dependent transgenic mouse model of multistage carcinogenesis. Cancer Res 2007;67:6777-85.
    • (2007) Cancer Res , vol.67 , pp. 6777-6785
    • Neutzner, M.1    Lopez, T.2    Feng, X.3    Bergmann-Leitner, E.S.4    Leitner, W.W.5    Udey, M.C.6
  • 25
    • 80052196437 scopus 로고    scopus 로고
    • Expression of milk fat globule epidermal growth factor-VIII may be an indicator of poor prognosis in malignant melanoma
    • Oba J, Moroi Y, Nakahara T, Abe T, Hagihara A, Furue M. Expression of milk fat globule epidermal growth factor-VIII may be an indicator of poor prognosis in malignant melanoma. Br J Dermatol 2011;165:506-12.
    • (2011) Br J Dermatol , vol.165 , pp. 506-512
    • Oba, J.1    Moroi, Y.2    Nakahara, T.3    Abe, T.4    Hagihara, A.5    Furue, M.6
  • 26
    • 55349147987 scopus 로고    scopus 로고
    • Milk fat globule EGF-8 promotes melanoma progression through coordinated Akt and twist signaling in the tumor microenvironment
    • Jinushi M, Nakazaki Y, Carrasco DR, Draganov D, Souders N, Johnson M, et al. Milk fat globule EGF-8 promotes melanoma progression through coordinated Akt and twist signaling in the tumor microenvironment. Cancer Res 2008;68:8889-98.
    • (2008) Cancer Res , vol.68 , pp. 8889-8898
    • Jinushi, M.1    Nakazaki, Y.2    Carrasco, D.R.3    Draganov, D.4    Souders, N.5    Johnson, M.6
  • 27
    • 79961074770 scopus 로고    scopus 로고
    • Tumor-associated macrophages regulate tumorigenicity and anticancer drug responses of cancer stem/initiating cells
    • Jinushi M, Chiba S, Yoshiyama H, Masutomi K, Kinoshita I, Dosaka-Akita H, et al. Tumor-associated macrophages regulate tumorigenicity and anticancer drug responses of cancer stem/initiating cells. Proc Natl Acad Sci U S A 2011;108:12425-30.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. 12425-12430
    • Jinushi, M.1    Chiba, S.2    Yoshiyama, H.3    Masutomi, K.4    Kinoshita, I.5    Dosaka-Akita, H.6
  • 28
    • 67449147143 scopus 로고    scopus 로고
    • Milk fat globule epidermal growth factor-8 blockade triggers tumor destruction through coordinated cell-autonomous and immune-mediated mechanisms
    • Jinushi M, Sato M, Kanamoto A, Itoh A, Nagai S, Koyasu S, et al. Milk fat globule epidermal growth factor-8 blockade triggers tumor destruction through coordinated cell-autonomous and immune-mediated mechanisms. J Exp Med 2009;206:1317-26.
    • (2009) J Exp Med , vol.206 , pp. 1317-1326
    • Jinushi, M.1    Sato, M.2    Kanamoto, A.3    Itoh, A.4    Nagai, S.5    Koyasu, S.6
  • 30
    • 80054954485 scopus 로고    scopus 로고
    • Potentiation of plateletderived growth factor receptor-b signaling mediated by integrin-associated MFG-E8
    • Motegi S, Garfield S, Feng X, Sardy M, Udey MC. Potentiation of plateletderived growth factor receptor-b signaling mediated by integrin-associated MFG-E8. Arterioscler Thromb Vasc Biol 2011;31:2653-64.
    • (2011) Arterioscler Thromb Vasc Biol , vol.31 , pp. 2653-2664
    • Motegi, S.1    Garfield, S.2    Feng, X.3    Sardy, M.4    Udey, M.C.5
  • 32
    • 50249119603 scopus 로고    scopus 로고
    • Mesenchymal stem cells: Isolation, characterisation and in vivo fluorescent dye tracking
    • Weir C, Morel-Kopp MC, Gill A, Tinworth K, Ladd L, Hunyor SN, et al. Mesenchymal stem cells: isolation, characterisation and in vivo fluorescent dye tracking. Heart Lung Circ 2008;17:395-403.
    • (2008) Heart Lung Circ , vol.17 , pp. 395-403
    • Weir, C.1    Morel-Kopp, M.C.2    Gill, A.3    Tinworth, K.4    Ladd, L.5    Hunyor, S.N.6
  • 33
    • 40949085086 scopus 로고    scopus 로고
    • Transplantation of hypoxia-preconditioned mesenchymal stem cells improves infarcted heart function via enhanced survival of implanted cells and angiogenesis
    • Hu X, Yu SP, Fraser JL, Lu Z, Ogle ME, Wang JA, et al. Transplantation of hypoxia-preconditioned mesenchymal stem cells improves infarcted heart function via enhanced survival of implanted cells and angiogenesis. J Thorac Cardiovasc Surg 2008;135:799-808.
    • (2008) J Thorac Cardiovasc Surg , vol.135 , pp. 799-808
    • Hu, X.1    Yu, S.P.2    Fraser, J.L.3    Lu, Z.4    Ogle, M.E.5    Wang, J.A.6
  • 34
    • 41149111290 scopus 로고    scopus 로고
    • In vitro hypoxic preconditioning of embryonic stem cells as a strategy of promoting cell survival and functional benefits after transplantation into the ischemic rat brain
    • Theus MH, Wei L, Cui L, Francis K, Hu X, Keogh C, et al. In vitro hypoxic preconditioning of embryonic stem cells as a strategy of promoting cell survival and functional benefits after transplantation into the ischemic rat brain. Exp Neurol 2008;210:656-70.
    • (2008) Exp Neurol , vol.210 , pp. 656-670
    • Theus, M.H.1    Wei, L.2    Cui, L.3    Francis, K.4    Hu, X.5    Keogh, C.6
  • 35
    • 33646690027 scopus 로고    scopus 로고
    • Human mesenchymal stem cells exert potent antitumorigenic effects in a model of Kaposi's sarcoma
    • Khakoo AY, Pati S, Anderson SA, Reid W, Elshal MF, Rovira II, et al. Human mesenchymal stem cells exert potent antitumorigenic effects in a model of Kaposi's sarcoma. J Exp Med 2006;203:1235-47.
    • (2006) J Exp Med , vol.203 , pp. 1235-1247
    • Khakoo, A.Y.1    Pati, S.2    Anderson, S.A.3    Reid, W.4    Elshal, M.F.5    Rovira, I.I.6
  • 36
    • 84896808531 scopus 로고    scopus 로고
    • Mesenchymal stem cells reciprocally regulate the M1/M2 balance in mouse bone marrow-derived macrophages
    • Cho DI, Kim MR, Jeong HY, Jeong HC, Jeong MH, Yoon SH, et al. Mesenchymal stem cells reciprocally regulate the M1/M2 balance in mouse bone marrow-derived macrophages. Exp Mol Med 2014;46:e70.
    • (2014) Exp Mol Med , vol.46 , pp. e70
    • Cho, D.I.1    Kim, M.R.2    Jeong, H.Y.3    Jeong, H.C.4    Jeong, M.H.5    Yoon, S.H.6
  • 37
    • 84905221047 scopus 로고    scopus 로고
    • Mesenchymal stem cells ameliorate rhabdomyolysis-induced acute kidney injury via the activation of M2 macrophages
    • Geng Y, Zhang L, Fu B, Zhang J, Hong Q, Hu J, et al. Mesenchymal stem cells ameliorate rhabdomyolysis-induced acute kidney injury via the activation of M2 macrophages. Stem Cell Res Ther 2014;5:80.
    • (2014) Stem Cell Res Ther , vol.5 , pp. 80
    • Geng, Y.1    Zhang, L.2    Fu, B.3    Zhang, J.4    Hong, Q.5    Hu, J.6
  • 38
    • 84896056890 scopus 로고    scopus 로고
    • Mouse bone marrow-derived mesenchymal stem cells induce macrophage M2 polarization through the nuclear factor-kBand signal transducer and activator of transcription 3 pathways
    • Gao S, Mao F, Zhang B, Zhang L, Zhang X, Wang M, et al. Mouse bone marrow-derived mesenchymal stem cells induce macrophage M2 polarization through the nuclear factor-kBand signal transducer and activator of transcription 3 pathways. Exp Biol Med 2014;239:366-75.
    • (2014) Exp Biol Med , vol.239 , pp. 366-375
    • Gao, S.1    Mao, F.2    Zhang, B.3    Zhang, L.4    Zhang, X.5    Wang, M.6
  • 39
    • 84905568615 scopus 로고    scopus 로고
    • Bone marrow mesenchymal stromal cells drive protective M2 microglia polarization after brain trauma
    • Zanier ER, Pischiutta F, Riganti L, Marchesi F, Turola E, Fumagalli S, et al. Bone marrow mesenchymal stromal cells drive protective M2 microglia polarization after brain trauma. Neurotherapeutics 2014;11: 679-95.
    • (2014) Neurotherapeutics , vol.11 , pp. 679-695
    • Zanier, E.R.1    Pischiutta, F.2    Riganti, L.3    Marchesi, F.4    Turola, E.5    Fumagalli, S.6
  • 40
  • 41
    • 84906871868 scopus 로고    scopus 로고
    • Polarization of prostate cancer-associated macrophages is induced by milk fat globule-EGF factor 8 (MFG-E8)-mediated efferocytosis
    • Soki FN, Koh AJ, Jones JD, Kim YW, Dai J, Keller ET, et al. Polarization of prostate cancer-associated macrophages is induced by milk fat globule-EGF factor 8 (MFG-E8)-mediated efferocytosis. J Biol Chem 2014;289: 24560-72.
    • (2014) J Biol Chem , vol.289 , pp. 24560-24572
    • Soki, F.N.1    Koh, A.J.2    Jones, J.D.3    Kim, Y.W.4    Dai, J.5    Keller, E.T.6
  • 42
    • 33847737677 scopus 로고    scopus 로고
    • Endothelin-1 and endothelin-3 promote invasive behavior via hypoxiainducible factor-1alpha in human melanoma cells
    • Spinella F, Rosano L, Di Castro V, Decandia S, Nicotra MR, Natali PG, et al. Endothelin-1 and endothelin-3 promote invasive behavior via hypoxiainducible factor-1alpha in human melanoma cells. Cancer Res 2007;67: 1725-34.
    • (2007) Cancer Res , vol.67 , pp. 1725-1734
    • Spinella, F.1    Rosano, L.2    Di Castro, V.3    Decandia, S.4    Nicotra, M.R.5    Natali, P.G.6
  • 43
    • 84883164592 scopus 로고    scopus 로고
    • Endothelin-1 induces the transactivation of vascular endothelial growth factor receptor-3 and modulates cell migration and vasculogenic mimicry in melanoma cells
    • Spinella F, Caprara V, Di Castro V, Rosano L, Cianfrocca R, Natali PG, et al. Endothelin-1 induces the transactivation of vascular endothelial growth factor receptor-3 and modulates cell migration and vasculogenic mimicry in melanoma cells. J Mol Med 2013;91:395-405.
    • (2013) J Mol Med , vol.91 , pp. 395-405
    • Spinella, F.1    Caprara, V.2    Di Castro, V.3    Rosano, L.4    Cianfrocca, R.5    Natali, P.G.6
  • 44
    • 0036740130 scopus 로고    scopus 로고
    • Endothelin-2 is a macrophage chemoattractant: Implications for macrophage distribution in tumors
    • Grimshaw MJ, Wilson JL, Balkwill FR. Endothelin-2 is a macrophage chemoattractant: implications for macrophage distribution in tumors. Eur J Immunol 2002;32:2393-400.
    • (2002) Eur J Immunol , vol.32 , pp. 2393-2400
    • Grimshaw, M.J.1    Wilson, J.L.2    Balkwill, F.R.3


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