-
1
-
-
84863522871
-
Addition of gemtuzumab ozogamicin to induction chemotherapy improves survival in older patients with acute myeloid leukemia
-
Burnett AK, Russell NH, Hills RK, et al. Addition of gemtuzumab ozogamicin to induction chemotherapy improves survival in older patients with acute myeloid leukemia. J Clin Oncol 2012;30:3924–3931.
-
(2012)
J Clin Oncol
, vol.30
, pp. 3924-3931
-
-
Burnett, A.K.1
Russell, N.H.2
Hills, R.K.3
-
2
-
-
84905560676
-
Addition of gemtuzumab ozogamicin to induction chemotherapy in adult patients with acute myeloid leukemia: A meta-analysis of individual patient data from randomized controlled trials
-
Hills RK, Castaigne S, Appelbaum FR, et al. Addition of gemtuzumab ozogamicin to induction chemotherapy in adult patients with acute myeloid leukemia: A meta-analysis of individual patient data from randomized controlled trials. Lancet Oncol 2014;15:986–996.
-
(2014)
Lancet Oncol
, vol.15
, pp. 986-996
-
-
Hills, R.K.1
Castaigne, S.2
Appelbaum, F.R.3
-
3
-
-
77449155696
-
Attempts to optimize induction and consolidation treatment in acute myeloid leukemia: Results of the MRC AML 12 trial
-
Burnett AK, Hills RK, Milligan DW, et al. Attempts to optimize induction and consolidation treatment in acute myeloid leukemia: Results of the MRC AML 12 trial. J Clin Oncol 2010;28:586–595.
-
(2010)
J Clin Oncol
, vol.28
, pp. 586-595
-
-
Burnett, A.K.1
Hills, R.K.2
Milligan, D.W.3
-
4
-
-
84875632298
-
Acute myeloid leukemia: 2013 Update on risk-stratification and management
-
Estey EH. Acute myeloid leukemia: 2013 Update on risk-stratification and management. Am J Hematol 2013;88:318–327.
-
(2013)
Am J Hematol
, vol.88
, pp. 318-327
-
-
Estey, E.H.1
-
6
-
-
84863297336
-
Selection of optimal alternative graft source: Mismatched unrelated donor, umbilical cord blood, or haploidentical transplant
-
Ballen KK, Koreth J, Chen YB, et al. Selection of optimal alternative graft source: Mismatched unrelated donor, umbilical cord blood, or haploidentical transplant. Blood 2012;119:1972–1980.
-
(2012)
Blood
, vol.119
, pp. 1972-1980
-
-
Ballen, K.K.1
Koreth, J.2
Chen, Y.B.3
-
7
-
-
49949091262
-
Direct intra bone transplant of unrelated cord-blood cells in acute leukemia: A phase I/II study
-
Frassoni F, Gualandi F, Podestà M, et al. Direct intra bone transplant of unrelated cord-blood cells in acute leukemia: A phase I/II study. Lancet Oncol 2008;9:831–839.
-
(2008)
Lancet Oncol
, vol.9
, pp. 831-839
-
-
Frassoni, F.1
Gualandi, F.2
Podestà, M.3
-
8
-
-
84912523216
-
Unmanipulated haploidentical transplants compared with other alternative donors and matched sibling grafts
-
Raiola AM, Dominietto A, Di Grazia C, et al. Unmanipulated haploidentical transplants compared with other alternative donors and matched sibling grafts. Biol Blood Marrow Transplant 2014;20:1573–1579.
-
(2014)
Biol Blood Marrow Transplant
, vol.20
, pp. 1573-1579
-
-
Raiola, A.M.1
Dominietto, A.2
Di Grazia, C.3
-
9
-
-
84893788771
-
Declining rates of treatment-related mortality in patients with newly diagnosed AML given ‘intense’ induction regimens: A report from SWOG and MD Anderson
-
Othus M, Kantarjian H, Petersdorf S, et al. Declining rates of treatment-related mortality in patients with newly diagnosed AML given ‘intense’ induction regimens: A report from SWOG and MD Anderson. Leukemia 2014;28:289–292.
-
(2014)
Leukemia
, vol.28
, pp. 289-292
-
-
Othus, M.1
Kantarjian, H.2
Petersdorf, S.3
-
10
-
-
78649429727
-
Reduced mortality after allogeneic hematopoietic-cell transplantation
-
Gooley TA, Chien JW, Pergam SA, et al. Reduced mortality after allogeneic hematopoietic-cell transplantation. N Engl J Med 2010;363:2091–2101.
-
(2010)
N Engl J Med
, vol.363
, pp. 2091-2101
-
-
Gooley, T.A.1
Chien, J.W.2
Pergam, S.A.3
-
11
-
-
84878372012
-
Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia
-
The Cancer Genome Atlas Research Network. Genomic and epigenomic landscapes of adult de novo acute myeloid leukemia. New Engl J Med 2013;368:2059–2074.
-
(2013)
New Engl J Med
, vol.368
, pp. 2059-2074
-
-
-
12
-
-
77449159028
-
European LeukemiaNet. Diagnosis and management of acute myeloid leukemia in adults: Recommendations from an international expert panel, on behalf of the European LeukemiaNet
-
Döhner H, Estey EH, Amadori S, et al. European LeukemiaNet. Diagnosis and management of acute myeloid leukemia in adults: Recommendations from an international expert panel, on behalf of the European LeukemiaNet. Blood 2010;115:453–474.
-
(2010)
Blood
, vol.115
, pp. 453-474
-
-
Döhner, H.1
Estey, E.H.2
Amadori, S.3
-
13
-
-
84871774636
-
Prognostic significance of the European Leukemia Net standardized system for reporting cytogenetic and molecular alterations in adults with acute myeloid leukemia
-
Mrózek K, Marcucci G, Nicolet D, et al. Prognostic significance of the European Leukemia Net standardized system for reporting cytogenetic and molecular alterations in adults with acute myeloid leukemia. J Clin Oncol 2012;30:4515–4523.
-
(2012)
J Clin Oncol
, vol.30
, pp. 4515-4523
-
-
Mrózek, K.1
Marcucci, G.2
Nicolet, D.3
-
14
-
-
77955914238
-
Refinement of cytogenetic classification in acute myeloid leukemia: Determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials
-
Grimwade D, Hills RK Moorman AV. National Cancer Research Institute Adult Leukaemia Working Group, et al. Refinement of cytogenetic classification in acute myeloid leukemia: Determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials. Blood 2010;16:354–365.
-
(2010)
Blood
, vol.16
, pp. 354-365
-
-
Grimwade, D.1
Hills, R.K.2
Moorman, A.V.3
-
15
-
-
0032188805
-
The importance of diagnostic cytogenetics on outcome in AML: Analysis of 1,612 patients entered into the MRC AML 10 trial. The Medical Research Council Adult and Children's Leukemia Working Parties
-
Grimwade D, Walker H, Oliver F, et al. The importance of diagnostic cytogenetics on outcome in AML: Analysis of 1,612 patients entered into the MRC AML 10 trial. The Medical Research Council Adult and Children's Leukemia Working Parties. Blood 1998;92:2322–2333.
-
(1998)
Blood
, vol.92
, pp. 2322-2333
-
-
Grimwade, D.1
Walker, H.2
Oliver, F.3
-
16
-
-
42949142189
-
German-Austrian Acute Myeloid Leukemia Study Group. Mutations and treatment outcome in cytogenetically normal acute myeloid leukemia
-
Schlenk RF, Döhner K, Krauter J, et al. German-Austrian Acute Myeloid Leukemia Study Group. Mutations and treatment outcome in cytogenetically normal acute myeloid leukemia. N Engl J Med 2008;358:909–918.
-
(2008)
N Engl J Med
, vol.358
, pp. 909-918
-
-
Schlenk, R.F.1
Döhner, K.2
Krauter, J.3
-
17
-
-
84932615484
-
2 in AML induction: Results from the UK NCRI AML17 trial in 1206 patients
-
2 in AML induction: Results from the UK NCRI AML17 trial in 1206 patients. Blood 2015;125:3878–3885.
-
(2015)
Blood
, vol.125
, pp. 3878-3885
-
-
Burnett, A.K.1
Russell, N.H.2
Hills, R.K.3
-
18
-
-
0005040904
-
A systematic collaborative overview of randomized trials comparing Idarubicin with daunorubicin (or other anthracyclines) as induction therapy for acute myeloid leukemia
-
The Aml Collaborative Group. A systematic collaborative overview of randomized trials comparing Idarubicin with daunorubicin (or other anthracyclines) as induction therapy for acute myeloid leukemia. Br J Haematol 1998;103:100–109.
-
(1998)
Br J Haematol
, vol.103
, pp. 100-109
-
-
-
19
-
-
0027450455
-
Fludarabine potentiates metabolism of cytarabine in patients with acute myelogenous leukemia during therapy
-
Gandhi V, Estey E, Keating MJ, Plunkett W. Fludarabine potentiates metabolism of cytarabine in patients with acute myelogenous leukemia during therapy. J Clinic Oncol 1993;11:116–124.
-
(1993)
J Clinic Oncol
, vol.11
, pp. 116-124
-
-
Gandhi, V.1
Estey, E.2
Keating, M.J.3
Plunkett, W.4
-
20
-
-
0030326145
-
High efficacy of fludarabine-containing therapy (FLAG-FLANG) in poor risk acute myeloid leukemia
-
Clavio M, Carrara P, Miglino M, et al. High efficacy of fludarabine-containing therapy (FLAG-FLANG) in poor risk acute myeloid leukemia. Haematologica 1996;81:513–520.
-
(1996)
Haematologica
, vol.81
, pp. 513-520
-
-
Clavio, M.1
Carrara, P.2
Miglino, M.3
-
21
-
-
0035035504
-
First line therapy with fludarabine combinations in 42 patients with either post myelodysplastic syndrome or therapy related acute myeloid leukemia
-
Clavio M, Gatto S, Beltrami G, et al. First line therapy with fludarabine combinations in 42 patients with either post myelodysplastic syndrome or therapy related acute myeloid leukemia. Leukemia and Lymphoma 2001;40:305–313.
-
(2001)
Leukemia and Lymphoma
, vol.40
, pp. 305-313
-
-
Clavio, M.1
Gatto, S.2
Beltrami, G.3
-
22
-
-
0036994363
-
Fludarabine, ARA-C, Idarubicin and G-CSF (FLAG-Ida), high dose ARA-C and early stem cell transplant. A feasible and effective therapeutic strategy for de novo AML patients
-
Clavio M, Gatto S, Beltrami G, et al. Fludarabine, ARA-C, Idarubicin and G-CSF (FLAG-Ida), high dose ARA-C and early stem cell transplant. A feasible and effective therapeutic strategy for de novo AML patients. J Exper and Clin Cancer Res 2002;21:481–487.
-
(2002)
J Exper and Clin Cancer Res
, vol.21
, pp. 481-487
-
-
Clavio, M.1
Gatto, S.2
Beltrami, G.3
-
23
-
-
84894365265
-
Optimization of chemotherapy for younger patients with acute myeloid leukemia: Results of the medical research council AML 15 trial
-
Burnett AK, Russell NH, Hills RK, et al. Optimization of chemotherapy for younger patients with acute myeloid leukemia: Results of the medical research council AML 15 trial. J Clin Oncol 2013;31:3360–3368.
-
(2013)
J Clin Oncol
, vol.31
, pp. 3360-3368
-
-
Burnett, A.K.1
Russell, N.H.2
Hills, R.K.3
-
24
-
-
0028800868
-
Phenotypic analysis of CD34 subpopulations in normal human bone marrow and its application for the detection of minimal residual disease
-
Macedo A, Orfao A, Ciudad J, et al. Phenotypic analysis of CD34 subpopulations in normal human bone marrow and its application for the detection of minimal residual disease. Leukemia 1995;9:1896–1901.
-
(1995)
Leukemia
, vol.9
, pp. 1896-1901
-
-
Macedo, A.1
Orfao, A.2
Ciudad, J.3
-
25
-
-
0029038651
-
Immunological detection of blast cell subpopulations in acute myeloblastic leukemia at diagnosis: Implications for minimal residual disease studies
-
Macedo A, Orfao A, Gonzalez M, et al. Immunological detection of blast cell subpopulations in acute myeloblastic leukemia at diagnosis: Implications for minimal residual disease studies. Leukemia 1995;9:993–998.
-
(1995)
Leukemia
, vol.9
, pp. 993-998
-
-
Macedo, A.1
Orfao, A.2
Gonzalez, M.3
-
26
-
-
58549114892
-
The role of multiparameter flow cytometry for detection of minimal residual disease in acute myeloid leukemia
-
Al-Mawali A, Gillis D, Lewis I. The role of multiparameter flow cytometry for detection of minimal residual disease in acute myeloid leukemia. Am J Clin Pathol 2009;131:16–26.
-
(2009)
Am J Clin Pathol
, vol.131
, pp. 16-26
-
-
Al-Mawali, A.1
Gillis, D.2
Lewis, I.3
-
27
-
-
70449726860
-
Real-time quantitative polymerase chain reaction detection of minimal residual disease by standardized WT1 assay to enhance risk stratification in acute myeloid leukemia: A European Leukemia Net study
-
Cilloni D, Renneville A, Hermitte F, et al. Real-time quantitative polymerase chain reaction detection of minimal residual disease by standardized WT1 assay to enhance risk stratification in acute myeloid leukemia: A European Leukemia Net study. J Clin Oncol 2009;1:5195–5201.
-
(2009)
J Clin Oncol
, pp. 1:5195-5201
-
-
Cilloni, D.1
Renneville, A.2
Hermitte, F.3
-
28
-
-
84867152043
-
Nucleophosmin gene-based monitoring in de novo cytogenetically normal acute myeloid leukemia with nucleophosmin gene mutations: Comparison with cytofluorimetric analysis and study of Wilms tumor gene 1 expression
-
Miglino M, Colombo N, Grasso R, et al. Nucleophosmin gene-based monitoring in de novo cytogenetically normal acute myeloid leukemia with nucleophosmin gene mutations: Comparison with cytofluorimetric analysis and study of Wilms tumor gene 1 expression. Leuk Lymphoma 2012;53:2214–2217.
-
(2012)
Leuk Lymphoma
, vol.53
, pp. 2214-2217
-
-
Miglino, M.1
Colombo, N.2
Grasso, R.3
-
29
-
-
0041440085
-
BAALC expression predicts clinical outcome of denovo acute myeloid leukemia patients with normal cytogenetics: A Cancer and Leukemia Group B Study
-
Baldus CD, Tanner SM, Ruppert AS, et al. BAALC expression predicts clinical outcome of denovo acute myeloid leukemia patients with normal cytogenetics: A Cancer and Leukemia Group B Study. Blood 2003;102:1613–1618.
-
(2003)
Blood
, vol.102
, pp. 1613-1618
-
-
Baldus, C.D.1
Tanner, S.M.2
Ruppert, A.S.3
-
30
-
-
33744464741
-
Quantitative assessment of minimal residual disease in acute myeloid leukemia carrying nucleophosmin (NPM1) gene mutations
-
Gorello P, Cazzaniga G, Alberti F, et al. Quantitative assessment of minimal residual disease in acute myeloid leukemia carrying nucleophosmin (NPM1) gene mutations. Leukemia 2006;20:1103–1108.
-
(2006)
Leukemia
, vol.20
, pp. 1103-1108
-
-
Gorello, P.1
Cazzaniga, G.2
Alberti, F.3
-
31
-
-
0031686409
-
Internal tandem duplication of the FLT3 gene is a novel modality of elongation mutation which causes constitutive activation of the product
-
Kiyoi H, Towatari M, Yokota S, et al. Internal tandem duplication of the FLT3 gene is a novel modality of elongation mutation which causes constitutive activation of the product. Leukemia 1998;12:1333–1337.
-
(1998)
Leukemia
, vol.12
, pp. 1333-1337
-
-
Kiyoi, H.1
Towatari, M.2
Yokota, S.3
-
33
-
-
84867397448
-
Single-unit umbilical cord blood transplantation from unrelated donors in patients with hematological malignancy using busulfan, thiotepa, fludarabine, and ATG as myeloablative conditioning regimen
-
Sanz J, Boluda JC Martín C. Grupo Español De Trasplante Hematopoyético Y Terapia Celular (GETH), et al. Single-unit umbilical cord blood transplantation from unrelated donors in patients with hematological malignancy using busulfan, thiotepa, fludarabine, and ATG as myeloablative conditioning regimen. Bone Marrow Transplant 2012;47:1287–1293.
-
(2012)
Bone Marrow Transplant
, vol.47
, pp. 1287-1293
-
-
Sanz, J.1
Boluda, J.C.2
Martín, C.3
-
34
-
-
84930420202
-
Unmanipulated haploidentical bone marrow transplantation and post-transplant cyclophosphamide for hematologic malignanices following a myeloablative conditioning: An update
-
Bacigalupo A, Dominietto A, Ghiso A, et al. Unmanipulated haploidentical bone marrow transplantation and post-transplant cyclophosphamide for hematologic malignanices following a myeloablative conditioning: An update. Bone Marrow Transplant 2015;50 Suppl 2:S37–S39.
-
(2015)
Bone Marrow Transplant
, vol.50 Suppl 2
, pp. S37-S39
-
-
Bacigalupo, A.1
Dominietto, A.2
Ghiso, A.3
-
35
-
-
84907318193
-
Survival analysis in hematologic malignancies: Recommendations for clinicians
-
Delgado J, Pereira A, Villamor N, et al. Survival analysis in hematologic malignancies: Recommendations for clinicians. Hematologica 2014;99:1410–1440.
-
(2014)
Hematologica
, vol.99
, pp. 1410-1440
-
-
Delgado, J.1
Pereira, A.2
Villamor, N.3
-
36
-
-
32944454861
-
Multicentre phase III trial on fludarabine, cytarabine (Ara-C), and Idarubicin versus Idarubicin, Ara-C and etoposide for induction treatment of younger, newly diagnosed acute myeloid leukemia patients
-
Russo D, Malagola M, De Vivo A, et al. Multicentre phase III trial on fludarabine, cytarabine (Ara-C), and Idarubicin versus Idarubicin, Ara-C and etoposide for induction treatment of younger, newly diagnosed acute myeloid leukemia patients. Br J Haematol 2005;131:172–179.
-
(2005)
Br J Haematol
, vol.131
, pp. 172-179
-
-
Russo, D.1
Malagola, M.2
De Vivo, A.3
-
37
-
-
84978179759
-
Fludarabine containing induction increases minimal residual disease clearance and improves survival in AML patients with concomitant NPM1 and FLT3-ITD mutations
-
Guolo F, Minetto P, Clavio M, et al. Fludarabine containing induction increases minimal residual disease clearance and improves survival in AML patients with concomitant NPM1 and FLT3-ITD mutations. Haematologica 2015;100:386.
-
(2015)
Haematologica
, vol.100
, pp. 386
-
-
Guolo, F.1
Minetto, P.2
Clavio, M.3
-
38
-
-
51649089123
-
Gemtuzumab-ozogamicin in combination with fludarabine, cytarabine, Idarubicin (FLAI-GO) as induction therapy in CD33-positive AML patients younger than 65 years
-
Candoni A, Martinelli G, Toffoletti E, et al. Gemtuzumab-ozogamicin in combination with fludarabine, cytarabine, Idarubicin (FLAI-GO) as induction therapy in CD33-positive AML patients younger than 65 years. Leuk Res 2008;32:1800–1808.
-
(2008)
Leuk Res
, vol.32
, pp. 1800-1808
-
-
Candoni, A.1
Martinelli, G.2
Toffoletti, E.3
-
39
-
-
0026623186
-
Determination of the maximum tolerated dose of Idarubicin when used in a combination chemotherapy program of reinduction of childhood ALL at first marrow relapse and a preliminary assessment of toxicity compared to that of daunorubicin: A report from the Childrens Cancer Study Group
-
Feig SA, Krailo MD, Harris RE, et al. Determination of the maximum tolerated dose of Idarubicin when used in a combination chemotherapy program of reinduction of childhood ALL at first marrow relapse and a preliminary assessment of toxicity compared to that of daunorubicin: A report from the Childrens Cancer Study Group. Med Pediatr Oncol 1992;20:124–129.
-
(1992)
Med Pediatr Oncol
, vol.20
, pp. 124-129
-
-
Feig, S.A.1
Krailo, M.D.2
Harris, R.E.3
-
40
-
-
79952122979
-
Randomized study of induction therapy comparing standard-dose Idarubicin with high-dose daunorubicin in adult patients with previously untreated acute myeloid leukemia: The JALSG AML201 Study
-
Ohtake S, Miyawaki S, Fujita H, et al. Randomized study of induction therapy comparing standard-dose Idarubicin with high-dose daunorubicin in adult patients with previously untreated acute myeloid leukemia: The JALSG AML201 Study. Blood 2011;117:2358–2365.
-
(2011)
Blood
, vol.117
, pp. 2358-2365
-
-
Ohtake, S.1
Miyawaki, S.2
Fujita, H.3
-
41
-
-
84883871342
-
De novo AML patients with favorable-intermediate karyotype may benefit from the addition of low-dose gemtuzumab ozogamicin (GO) to fludarabine, Ara-C and Idarubicin (FLAI): A contribution to the reopened “GO question
-
Clavio M, Cruciani F, Minetto P, et al. De novo AML patients with favorable-intermediate karyotype may benefit from the addition of low-dose gemtuzumab ozogamicin (GO) to fludarabine, Ara-C and Idarubicin (FLAI): A contribution to the reopened “GO question”. Ann Hematol 2013;92:1309–1318.
-
(2013)
Ann Hematol
, vol.92
, pp. 1309-1318
-
-
Clavio, M.1
Cruciani, F.2
Minetto, P.3
-
42
-
-
0035885973
-
Early immunophenotypical evaluation of minimal residual disease in acute myeloid leukemia identifies different patient risk groups and may contribute to post induction treatment stratification
-
San Miguel JF, Vidriales MB, López-Berges C, et al. Early immunophenotypical evaluation of minimal residual disease in acute myeloid leukemia identifies different patient risk groups and may contribute to post induction treatment stratification. Blood 2001;98:1746–1751.
-
(2001)
Blood
, vol.98
, pp. 1746-1751
-
-
San Miguel, J.F.1
Vidriales, M.B.2
López-Berges, C.3
-
43
-
-
84908460791
-
Post-remission therapy for acute myeloid leukemia
-
Schlenk RF. Post-remission therapy for acute myeloid leukemia. Haematologica 2014;99:1663–1670.
-
(2014)
Haematologica
, vol.99
, pp. 1663-1670
-
-
Schlenk, R.F.1
-
44
-
-
79960127726
-
Monitoring of minimal residual disease in NPM1-mutated acute myeloid leukemia: A study from the German-Austrian acute myeloid leukemia study group
-
Krönke J, Schlenk RF, Jensen KO, et al. Monitoring of minimal residual disease in NPM1-mutated acute myeloid leukemia: A study from the German-Austrian acute myeloid leukemia study group. J Clin Oncol 2011;29:2709–2716.
-
(2011)
J Clin Oncol
, vol.29
, pp. 2709-2716
-
-
Krönke, J.1
Schlenk, R.F.2
Jensen, K.O.3
-
45
-
-
84888135840
-
Integrating post induction WT1 quantification and flow-cytometry results improves minimal residual disease stratification in acute myeloid leukemia
-
Marani C, Clavio M, Grasso R, et al. Integrating post induction WT1 quantification and flow-cytometry results improves minimal residual disease stratification in acute myeloid leukemia. Leuk Res 2013;37:1606–1611.
-
(2013)
Leuk Res
, vol.37
, pp. 1606-1611
-
-
Marani, C.1
Clavio, M.2
Grasso, R.3
-
46
-
-
84937794580
-
How I treat refractory and early relapsed acute myeloid leukemia
-
Thol F, Schlenk RF, Heuser M, Ganser A. How I treat refractory and early relapsed acute myeloid leukemia. Blood 2015;126:319–327.
-
(2015)
Blood
, vol.126
, pp. 319-327
-
-
Thol, F.1
Schlenk, R.F.2
Heuser, M.3
Ganser, A.4
|