Lactoferrin is an allosteric enhancer of the proteolytic activity of cathepsin G

PLoS ONE

Volumn 11, Issue 3, 2016, Pages

  Eipper, Steffen ^a   Steiner, Robin ^a   Lesner, Adam ^b   Sienczyk, Marcin ^c   Palesch, David ^a   Halatsch, Marc Eric ^a   Zaczynska, Ewa ^d   Heim, Christopher ^e   Hartmann, Marcus D ^e   Zimecki, Michal ^d   Wirtz, Christian Rainer ^a   Burster, Timo ^a  

^a UNIVERSITY HOSPITAL ULM   (Germany)

^b UNIVERSITY OF GDA SK   (Poland)

^c WROCLAW UNIVERSITY OF TECHNOLOGY   (Poland)

^d INSTITUTE OF IMMUNOLOGY AND EXPERIMENTAL THERAPY   (Poland)

^e MAX PLANCK INSTITUTE FOR DEVELOPMENTAL BIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CATHEPSIN G; ELASTASE; LACTOFERRIN; MYELOBLASTIN; PADGEM PROTEIN; PROTEINASE; SERINE PROTEINASE; CTSG PROTEIN, HUMAN; LEUKOCYTE ELASTASE; LTF PROTEIN, HUMAN;

ALLOSTERISM; ANTIGEN EXPRESSION; ANTIGEN PRESENTATION; ARTICLE; CATALYSIS; CELL SURFACE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME RELEASE; ENZYME SPECIFICITY; GRANULOCYTE; HUMAN; IMMUNE RESPONSE; INFLAMMATION; INNATE IMMUNITY; NEUTROPHIL; PROTEIN DEGRADATION; SUPERNATANT; THROMBOCYTE ACTIVATION; BIOCATALYSIS; CONDITIONED MEDIUM; DRUG EFFECT; ENZYME ACTIVATION; IMMUNOBLOTTING; IMMUNOLOGY; METABOLISM; PH; PHARMACOLOGY; POLYACRYLAMIDE GEL ELECTROPHORESIS;

ALLOSTERIC REGULATION; BIOCATALYSIS; CATHEPSIN G; CULTURE MEDIA, CONDITIONED; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME ACTIVATION; GRANULOCYTES; HUMANS; HYDROGEN-ION CONCENTRATION; IMMUNITY, INNATE; IMMUNOBLOTTING; INFLAMMATION; LACTOFERRIN; LEUKOCYTE ELASTASE; PLATELET ACTIVATION; PROTEOLYSIS; SUBSTRATE SPECIFICITY;

EID: 84978054079     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0151509     Document Type: Article

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