-
1
-
-
77956030786
-
Inhibition of mutated, activated BRAF in metastatic melanoma
-
Flaherty KT, Puzanov I, Kim KB, Ribas A, McArthur GA, Sosman JA, et al. Inhibition of mutated, activated BRAF in metastatic melanoma. N Engl J Med. 2010;363(9):809-19. doi: 10.1056/NEJMoa1002011.
-
(2010)
N Engl J Med.
, vol.363
, Issue.9
, pp. 809-819
-
-
Flaherty, K.T.1
Puzanov, I.2
Kim, K.B.3
Ribas, A.4
McArthur, G.A.5
Sosman, J.A.6
-
2
-
-
22044445517
-
Erlotinib in previously treated non-small-cell lung cancer
-
Shepherd FA, Rodrigues Pereira J, Ciuleanu T, Tan EH, Hirsh V, Thongprasert S, et al. Erlotinib in previously treated non-small-cell lung cancer. N Engl J Med. 2005;353(2):123-32. doi: 10.1056/NEJMoa050753.
-
(2005)
N Engl J Med.
, vol.353
, Issue.2
, pp. 123-132
-
-
Shepherd, F.A.1
Rodrigues Pereira, J.2
Ciuleanu, T.3
Tan, E.H.4
Hirsh, V.5
Thongprasert, S.6
-
3
-
-
84901936604
-
Enabling a genetically informed approach to cancer medicine: a retrospective evaluation of the impact of comprehensive tumor profiling using a targeted next-generation sequencing panel
-
Johnson DB, Dahlman KH, Knol J, Gilbert J, Puzanov I, Means-Powell J, et al. Enabling a genetically informed approach to cancer medicine: a retrospective evaluation of the impact of comprehensive tumor profiling using a targeted next-generation sequencing panel. Oncologist. 2014;19(6):616-22. doi: 10.1634/theoncologist.2014-0011.
-
(2014)
Oncologist
, vol.19
, Issue.6
, pp. 616-622
-
-
Johnson, D.B.1
Dahlman, K.H.2
Knol, J.3
Gilbert, J.4
Puzanov, I.5
Means-Powell, J.6
-
4
-
-
77954566882
-
Rapid targeted mutational analysis of human tumours: a clinical platform to guide personalized cancer medicine
-
Dias-Santagata D, Akhavanfard S, David SS, Vernovsky K, Kuhlmann G, Boisvert SL, et al. Rapid targeted mutational analysis of human tumours: a clinical platform to guide personalized cancer medicine. EMBO Mol Med. 2010;2(5):146-58. doi: 10.1002/emmm.201000070.
-
(2010)
EMBO Mol Med.
, vol.2
, Issue.5
, pp. 146-158
-
-
Dias-Santagata, D.1
Akhavanfard, S.2
David, S.S.3
Vernovsky, K.4
Kuhlmann, G.5
Boisvert, S.L.6
-
5
-
-
84922793976
-
Ewing sarcoma mimicking atypical carcinoid tumor: detection of unexpected genomic alterations demonstrates the use of next generation sequencing as a diagnostic tool
-
Doyle LA, Wong KK, Bueno R, Dal Cin P, Fletcher JA, Sholl LM, et al. Ewing sarcoma mimicking atypical carcinoid tumor: detection of unexpected genomic alterations demonstrates the use of next generation sequencing as a diagnostic tool. Cancer Genet. 2014;207(7-8):335-9. doi: 10.1016/j.cancergen.2014.08.004.
-
(2014)
Cancer Genet.
, vol.207
, Issue.7-8
, pp. 335-339
-
-
Doyle, L.A.1
Wong, K.K.2
Bueno, R.3
Dal Cin, P.4
Fletcher, J.A.5
Sholl, L.M.6
-
6
-
-
84936114621
-
BreaKmer: detection of structural variation in targeted massively parallel sequencing data using kmers
-
Abo RP, Ducar M, Garcia EP, Thorner AR, Rojas-Rudilla V, Lin L, et al. BreaKmer: detection of structural variation in targeted massively parallel sequencing data using kmers. Nucleic Acids Res. 2014. doi: 10.1093/nar/gku1211.
-
(2014)
Nucleic Acids Res
-
-
Abo, R.P.1
Ducar, M.2
Garcia, E.P.3
Thorner, A.R.4
Rojas-Rudilla, V.5
Lin, L.6
-
7
-
-
0344987881
-
A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome
-
Cools J, DeAngelo DJ, Gotlib J, Stover EH, Legare RD, Cortes J, et al. A tyrosine kinase created by fusion of the PDGFRA and FIP1L1 genes as a therapeutic target of imatinib in idiopathic hypereosinophilic syndrome. N Engl J Med. 2003;348(13):1201-14. doi: 10.1056/NEJMoa025217.
-
(2003)
N Engl J Med.
, vol.348
, Issue.13
, pp. 1201-1214
-
-
Cools, J.1
DeAngelo, D.J.2
Gotlib, J.3
Stover, E.H.4
Legare, R.D.5
Cortes, J.6
-
8
-
-
70349256226
-
The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes
-
Vardiman JW, Thiele J, Arber DA, Brunning RD, Borowitz MJ, Porwit A, et al. The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes. Blood. 2009;114(5):937-51. doi: 10.1182/blood-2009-03-209262.
-
(2009)
Blood
, vol.114
, Issue.5
, pp. 937-951
-
-
Vardiman, J.W.1
Thiele, J.2
Arber, D.A.3
Brunning, R.D.4
Borowitz, M.J.5
Porwit, A.6
-
9
-
-
0037596569
-
Discovery of a fusion kinase in EOL-1 cells and idiopathic hypereosinophilic syndrome
-
Griffin JH, Leung J, Bruner RJ, Caligiuri MA, Briesewitz R. Discovery of a fusion kinase in EOL-1 cells and idiopathic hypereosinophilic syndrome. Proc Natl Acad Sci USA. 2003;100(13):7830-5. doi: 10.1073/pnas.0932698100.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, Issue.13
, pp. 7830-7835
-
-
Griffin, J.H.1
Leung, J.2
Bruner, R.J.3
Caligiuri, M.A.4
Briesewitz, R.5
-
10
-
-
33744484267
-
Activation of FIP1L1-PDGFRalpha requires disruption of the juxtamembrane domain of PDGFRalpha and is FIP1L1-independent
-
Stover EH, Chen J, Folens C, Lee BH, Mentens N, Marynen P, et al. Activation of FIP1L1-PDGFRalpha requires disruption of the juxtamembrane domain of PDGFRalpha and is FIP1L1-independent. Proc Natl Acad Sci USA. 2006;103(21):8078-83. doi: 10.1073/pnas.0601192103.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, Issue.21
, pp. 8078-8083
-
-
Stover, E.H.1
Chen, J.2
Folens, C.3
Lee, B.H.4
Mentens, N.5
Marynen, P.6
-
11
-
-
84862506066
-
Complete response of myeloid sarcoma with FIP1L1-PDGFRA -associated myeloproliferative neoplasms to imatinib mesylate monotherapy
-
Tang TC, Chang H, Chuang WY. Complete response of myeloid sarcoma with FIP1L1-PDGFRA -associated myeloproliferative neoplasms to imatinib mesylate monotherapy. Acta Haematol. 2012;128(2):83-7. doi: 10.1159/000338217.
-
(2012)
Acta Haematol
, vol.128
, Issue.2
, pp. 83-87
-
-
Tang, T.C.1
Chang, H.2
Chuang, W.Y.3
-
12
-
-
84899128502
-
Discovery of imatinib-responsive FIP1L1-PDGFRA mutation during refractory acute myeloid leukemia transformation of chronic myelomonocytic leukemia
-
Shah S, Loghavi S, Garcia-Manero G, Khoury JD. Discovery of imatinib-responsive FIP1L1-PDGFRA mutation during refractory acute myeloid leukemia transformation of chronic myelomonocytic leukemia. J Hematol Oncol. 2014;7:26. doi: 10.1186/1756-8722-7-26.
-
(2014)
J Hematol Oncol.
, vol.7
, pp. 26
-
-
Shah, S.1
Loghavi, S.2
Garcia-Manero, G.3
Khoury, J.D.4
-
13
-
-
84871623818
-
A case of nonleukemic myeloid sarcoma with FIP1L1-PDGFRA rearrangement: an unusual presentation of a rare disease
-
Chen D, Bachanova V, Ketterling RP, Begna KH, Hanson CA, Viswanatha DS. A case of nonleukemic myeloid sarcoma with FIP1L1-PDGFRA rearrangement: an unusual presentation of a rare disease. Am J Surg Pathol. 2013;37(1):147-51. doi: 10.1097/PAS.0b013e31826df00b.
-
(2013)
Am J Surg Pathol
, vol.37
, Issue.1
, pp. 147-151
-
-
Chen, D.1
Bachanova, V.2
Ketterling, R.P.3
Begna, K.H.4
Hanson, C.A.5
Viswanatha, D.S.6
-
14
-
-
34249742721
-
Recurrent finding of the FIP1L1-PDGFRA fusion gene in eosinophilia-associated acute myeloid leukemia and lymphoblastic T-cell lymphoma
-
Metzgeroth G, Walz C, Score J, Siebert R, Schnittger S, Haferlach C, et al. Recurrent finding of the FIP1L1-PDGFRA fusion gene in eosinophilia-associated acute myeloid leukemia and lymphoblastic T-cell lymphoma. Leukemia. 2007;21(6):1183-8. doi: 10.1038/sj.leu.2404662.
-
(2007)
Leukemia
, vol.21
, Issue.6
, pp. 1183-1188
-
-
Metzgeroth, G.1
Walz, C.2
Score, J.3
Siebert, R.4
Schnittger, S.5
Haferlach, C.6
-
15
-
-
84907996097
-
Strategies for modern biomarker and drug development in oncology
-
Smith AD, Roda D, Yap TA. Strategies for modern biomarker and drug development in oncology. J Hematol Oncol. 2014;7(1):70. doi: 10.1186/s13045-014-0070-8.
-
(2014)
J Hematol Oncol.
, vol.7
, Issue.1
, pp. 70
-
-
Smith, A.D.1
Roda, D.2
Yap, T.A.3
-
16
-
-
84935825445
-
STUMP un"stumped": anti-tumor response to anaplastic lymphoma kinase (ALK) inhibitor based targeted therapy in uterine inflammatory myofibroblastic tumor with myxoid features harboring DCTN1-ALK fusion
-
Subbiah V, McMahon C, Patel S, Zinner R, Silva EG, Elvin JA, et al. STUMP un"stumped": anti-tumor response to anaplastic lymphoma kinase (ALK) inhibitor based targeted therapy in uterine inflammatory myofibroblastic tumor with myxoid features harboring DCTN1-ALK fusion. J Hematol Oncol. 2015;8:66. doi: 10.1186/s13045-015-0160-2.
-
(2015)
J Hematol Oncol.
, vol.8
, pp. 66
-
-
Subbiah, V.1
McMahon, C.2
Patel, S.3
Zinner, R.4
Silva, E.G.5
Elvin, J.A.6
|