Plasma Trimethylamine N-Oxide, a Gut Microbe–Generated Phosphatidylcholine Metabolite, Is Associated With Atherosclerotic Burden

Journal of the American College of Cardiology

Volumn 67, Issue 22, 2016, Pages 2620-2628

  Senthong, Vichai ^a,b   Li, Xinmin S ^a   Hudec, Timothy ^a   Coughlin, John ^a   Wu, Yuping ^c   Levison, Bruce ^a   Wang, Zeneng ^a   Hazen, Stanley L ^a   Tang, W H Wilson ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

^b KHON KAEN UNIVERSITY   (Thailand)

^c CLEVELAND STATE UNIVERSITY   (United States)

Author keywords

diffuse; focal; myonecrosis; risk factors; SYNTAX score; troponin T

Indexed keywords

ACETYLSALICYLIC ACID; ANGIOTENSIN RECEPTOR ANTAGONIST; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; C REACTIVE PROTEIN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; TRIMETHYLAMINE OXIDE; TROPONIN T; BIOLOGICAL MARKER; METHYLAMINE; TRIMETHYLOXAMINE;

ADULT; AGED; ARTICLE; ATHEROSCLEROTIC PLAQUE; BLOOD ANALYSIS; BODY MASS; CARDIOVASCULAR PARAMETERS; CARDIOVASCULAR RISK; COHORT ANALYSIS; CONTROLLED STUDY; CORONARY ANGIOGRAPHY; CORONARY ARTERY DISEASE; CROSS-SECTIONAL STUDY; DISEASE ASSOCIATION; FEMALE; FRAMINGHAM RISK SCORE; GLOMERULUS FILTRATION RATE; HUMAN; KIDNEY FUNCTION; LIPID BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; MASS SPECTROMETRY; MUSCLE NECROSIS; PATHOGENESIS; PERCUTANEOUS CORONARY INTERVENTION; PRIORITY JOURNAL; PROSPECTIVE STUDY; RISK ASSESSMENT; RISK FACTOR; SYNTAX SCORE; BLOOD; DIAGNOSTIC IMAGING; MIDDLE AGED; SEVERITY OF ILLNESS INDEX;

AGED; BIOMARKERS; COHORT STUDIES; CORONARY ANGIOGRAPHY; CORONARY ARTERY DISEASE; FEMALE; HUMANS; MALE; MASS SPECTROMETRY; METHYLAMINES; MIDDLE AGED; SEVERITY OF ILLNESS INDEX; TROPONIN T;

EID: 84977669212     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2016.03.546     Document Type: Article

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