메뉴 건너뛰기




Volumn 459, Issue , 2016, Pages 5-9

VOC breath biomarkers in lung cancer

Author keywords

Biomarker; Breath analysis; Diagnostics; Lung cancer; Screening; VOC

Indexed keywords

2 BUTANONE; ETHYLBENZENE; HEXANAL; ISOPRENE; PROPANOL; STYRENE; VOLATILE ORGANIC COMPOUND; TUMOR MARKER;

EID: 84977638407     PISSN: 00098981     EISSN: 18733492     Source Type: Journal    
DOI: 10.1016/j.cca.2016.05.013     Document Type: Review
Times cited : (219)

References (56)
  • 1
    • 84942587651 scopus 로고    scopus 로고
    • Fact sheet N297 - Cancer
    • Url: (Accessed January 2016)
    • [1] World Health Organization, Fact sheet N297 - Cancer. Url: http://www.who.int/mediacentre/factsheets/fs297/en/ (Accessed January 2016).
    • World Health Organization1
  • 2
    • 84855692909 scopus 로고    scopus 로고
    • What are the key statistics about lung cancer?
    • Url: (Accessed January 2016)
    • [2] Inc. American Cancer Society, What are the key statistics about lung cancer?. Url: http://www.cancer.org/cancer/lungcancer-non-smallcell/detailedguide/non-small-cell-lung-cancer-key-statistics (Accessed January 2016).
    • Inc. American Cancer Society1
  • 3
    • 84918815964 scopus 로고    scopus 로고
    • Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012
    • [3] Ferlay, J., Soerjomataram, I., Dikshit, R., Eser, S., Mathers, C., Rebelo, M., et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int. J. Cancer 136 (2015), E359–E386.
    • (2015) Int. J. Cancer , vol.136 , pp. E359-E386
    • Ferlay, J.1    Soerjomataram, I.2    Dikshit, R.3    Eser, S.4    Mathers, C.5    Rebelo, M.6
  • 5
    • 0035117342 scopus 로고    scopus 로고
    • American Cancer Society guidelines for the early detection of cancer: update of early detection guidelines for prostate, colorectal, and endometrial cancers
    • [5] Smith, R.A., von Eschenbach, A.C., Wender, R., Levin, B., Byers, T., Rothenberger, D., Brooks, D., et al. American Cancer Society guidelines for the early detection of cancer: update of early detection guidelines for prostate, colorectal, and endometrial cancers. CA Cancer J. Clin. 51 (2001), 38–75.
    • (2001) CA Cancer J. Clin. , vol.51 , pp. 38-75
    • Smith, R.A.1    von Eschenbach, A.C.2    Wender, R.3    Levin, B.4    Byers, T.5    Rothenberger, D.6    Brooks, D.7
  • 6
    • 85010699523 scopus 로고    scopus 로고
    • WHO International Programme on Chemical Safety Biomarkers in Risk Assessment: Validity and Validation
    • Url: (Accessed January 2016)
    • [6] WHO International Programme on Chemical Safety Biomarkers in Risk Assessment: Validity and Validation. Url: http://www.inchem.org/documents/ehc/ehc/ehc222.htm (Accessed January 2016).
  • 8
    • 32944463513 scopus 로고    scopus 로고
    • Diagnostic accuracy of canine scent detection in early- and late-stage lung and breast cancers
    • [8] McCulloch, M., Jezierski, T., Broffman, M., Hubbard, A., Turner, K., Janecki, T., Diagnostic accuracy of canine scent detection in early- and late-stage lung and breast cancers. Integr. Cancer Ther. 5 (2006), 30–39.
    • (2006) Integr. Cancer Ther. , vol.5 , pp. 30-39
    • McCulloch, M.1    Jezierski, T.2    Broffman, M.3    Hubbard, A.4    Turner, K.5    Janecki, T.6
  • 9
    • 84930621400 scopus 로고    scopus 로고
    • Application of an artificial neural network model for selection of potential lung cancer biomarkers
    • [9] Ligor, T., Pater, L., Buszewski, B., Application of an artificial neural network model for selection of potential lung cancer biomarkers. J. Breath Res., 9, 2015, 027106.
    • (2015) J. Breath Res. , vol.9 , pp. 027106
    • Ligor, T.1    Pater, L.2    Buszewski, B.3
  • 10
    • 70450247116 scopus 로고    scopus 로고
    • Exhaled pentane as a possible marker for survival and lipid peroxidation during radiotherapy for lung cancer—a pilot study
    • [10] Crohns, M., Saarelainen, S., Laitinen, J., Peltonen, K., Alho, H., Kellokumpu-Lehtinen, P., Exhaled pentane as a possible marker for survival and lipid peroxidation during radiotherapy for lung cancer—a pilot study. Free Radic. Res. 43 (2009), 965–974.
    • (2009) Free Radic. Res. , vol.43 , pp. 965-974
    • Crohns, M.1    Saarelainen, S.2    Laitinen, J.3    Peltonen, K.4    Alho, H.5    Kellokumpu-Lehtinen, P.6
  • 11
    • 30544454538 scopus 로고    scopus 로고
    • Application of laser spectroscopy for measurement of exhaled ethane in patients with lung cancer
    • [11] Skeldon, K.D., McMillan, L.C., Wyse, C.A., Monk, S.D., Gibson, G., Patterson, C., et al. Application of laser spectroscopy for measurement of exhaled ethane in patients with lung cancer. Respir. Med. 100 (2006), 300–306.
    • (2006) Respir. Med. , vol.100 , pp. 300-306
    • Skeldon, K.D.1    McMillan, L.C.2    Wyse, C.A.3    Monk, S.D.4    Gibson, G.5    Patterson, C.6
  • 13
    • 0003699932 scopus 로고    scopus 로고
    • Compendium of Methods for the Determination of Toxic Organic Compounds in Ambient Air, TO-15a
    • second ed.
    • [13] US Environmental Protection Agency, Compendium of Methods for the Determination of Toxic Organic Compounds in Ambient Air, TO-15a. second ed., 1999.
    • (1999)
    • US Environmental Protection Agency1
  • 14
    • 84873662286 scopus 로고    scopus 로고
    • Stability of selected volatile breath constituents in Tedlar, Kynar and Flexfilm sampling bags
    • [14] Mochalski, P., King, J., Unterkofler, K., Amann, A., Stability of selected volatile breath constituents in Tedlar, Kynar and Flexfilm sampling bags. Analyst 138 (2013), 1405–1418.
    • (2013) Analyst , vol.138 , pp. 1405-1418
    • Mochalski, P.1    King, J.2    Unterkofler, K.3    Amann, A.4
  • 15
    • 34247487094 scopus 로고    scopus 로고
    • The suitability of Tedlar bags for breath sampling in medical diagnostic research
    • [15] Steeghs, M.M.L., Cristescu, S.M., Harren, F.J.M., The suitability of Tedlar bags for breath sampling in medical diagnostic research. Physiol. Meas. 28 (2007), 73–84.
    • (2007) Physiol. Meas. , vol.28 , pp. 73-84
    • Steeghs, M.M.L.1    Cristescu, S.M.2    Harren, F.J.M.3
  • 16
    • 84869193541 scopus 로고    scopus 로고
    • Volatile organic compounds of lung cancer and possible biochemical pathways
    • [16] Hakim, M., Broza, Y.Y., Barash, O., Peled, N., Phillips, M., Amann, A., et al. Volatile organic compounds of lung cancer and possible biochemical pathways. Chem. Rev. 112 (2012), 5949–5966.
    • (2012) Chem. Rev. , vol.112 , pp. 5949-5966
    • Hakim, M.1    Broza, Y.Y.2    Barash, O.3    Peled, N.4    Phillips, M.5    Amann, A.6
  • 17
    • 84903186057 scopus 로고    scopus 로고
    • Exhaled breath analysis for lung cancer
    • [17] Dent, A.G., Sutedja, T.G., Zimmerman, P.V., Exhaled breath analysis for lung cancer. J. Thorac. Dis. 5:Suppl. 5 (2013), 540–550.
    • (2013) J. Thorac. Dis. , vol.5 , Issue.Suppl. 5 , pp. 540-550
    • Dent, A.G.1    Sutedja, T.G.2    Zimmerman, P.V.3
  • 19
    • 84866163026 scopus 로고    scopus 로고
    • Dependence of exhaled breath composition on exogenous factors, smoking habits and exposure to air pollutants
    • [19] Filipiak, W., Ruzsanyi, V., Mochalski, P., Filipiak, A., Bajtarevic, A., Ager, C., et al. Dependence of exhaled breath composition on exogenous factors, smoking habits and exposure to air pollutants. J. Breath Res., 6, 2012, 036008.
    • (2012) J. Breath Res. , vol.6 , pp. 036008
    • Filipiak, W.1    Ruzsanyi, V.2    Mochalski, P.3    Filipiak, A.4    Bajtarevic, A.5    Ager, C.6
  • 21
    • 50349095278 scopus 로고    scopus 로고
    • Analysis of volatile organic compounds in the exhaled breath for the diagnosis of lung cancer
    • [21] Mazzone, P.J., Analysis of volatile organic compounds in the exhaled breath for the diagnosis of lung cancer. J. Thorac. Oncol. 3 (2008), 774–780.
    • (2008) J. Thorac. Oncol. , vol.3 , pp. 774-780
    • Mazzone, P.J.1
  • 22
    • 0034236697 scopus 로고    scopus 로고
    • Theory of solid-phase microextraction
    • [22] Pawliszyn, J., Theory of solid-phase microextraction. J. Chromatogr. Sci. 38 (2000), 270–278.
    • (2000) J. Chromatogr. Sci. , vol.38 , pp. 270-278
    • Pawliszyn, J.1
  • 23
    • 0031568680 scopus 로고    scopus 로고
    • Solid-phase microextraction for the analysis of human breath
    • [23] Grote, C., Pawliszyn, J., Solid-phase microextraction for the analysis of human breath. Anal. Chem. 69 (1997), 587–596.
    • (1997) Anal. Chem. , vol.69 , pp. 587-596
    • Grote, C.1    Pawliszyn, J.2
  • 25
    • 68149114145 scopus 로고    scopus 로고
    • Determining concentration patterns of volatile compounds in exhaled breath by PTR-MS
    • [25] Schwarz, K., Filipiak, W., Amann, A., Determining concentration patterns of volatile compounds in exhaled breath by PTR-MS. J. Breath Res., 3, 2009, 027002.
    • (2009) J. Breath Res. , vol.3 , pp. 027002
    • Schwarz, K.1    Filipiak, W.2    Amann, A.3
  • 27
    • 63249102023 scopus 로고    scopus 로고
    • An electronic nose in the discrimination of patients with non-small cell lung cancer and COPD
    • [27] Dragonieri, S., Annema, J.T., Schot, R., van der Schee, M.P.C., Spanevello, A., Carratú, P., et al. An electronic nose in the discrimination of patients with non-small cell lung cancer and COPD. Lung Cancer 64 (2009), 166–170.
    • (2009) Lung Cancer , vol.64 , pp. 166-170
    • Dragonieri, S.1    Annema, J.T.2    Schot, R.3    van der Schee, M.P.C.4    Spanevello, A.5    Carratú, P.6
  • 29
    • 84916613270 scopus 로고    scopus 로고
    • Exhaled breath analysis for lung cancer detection using ion mobility spectrometry
    • [29] Handa, H., Usuba, A., Maddula, S., Baumbach, J.I., Mineshita, M., Miyazawa, T., Exhaled breath analysis for lung cancer detection using ion mobility spectrometry. PLoS One, 9, 2014, e114555.
    • (2014) PLoS One , vol.9 , pp. e114555
    • Handa, H.1    Usuba, A.2    Maddula, S.3    Baumbach, J.I.4    Mineshita, M.5    Miyazawa, T.6
  • 30
    • 69749091957 scopus 로고    scopus 로고
    • Ion mobility spectrometry for the detection of volatile organic compounds in exhaled breath of patients with lung cancer: results of a pilot study
    • [30] Westhoff, M., Litterst, P., Freitag, L., Urfer, W., Bader, S., Baumbach, J.I., Ion mobility spectrometry for the detection of volatile organic compounds in exhaled breath of patients with lung cancer: results of a pilot study. Thorax 64 (2009), 744–748.
    • (2009) Thorax , vol.64 , pp. 744-748
    • Westhoff, M.1    Litterst, P.2    Freitag, L.3    Urfer, W.4    Bader, S.5    Baumbach, J.I.6
  • 31
    • 84956584662 scopus 로고    scopus 로고
    • Noninvasive detection of lung cancer using exhaled breath
    • [31] Fu, X.A., Li, M., Knipp, R.J., Nantz, M.H., Bousamra, M., Noninvasive detection of lung cancer using exhaled breath. Cancer Med. 3 (2014), 174–181.
    • (2014) Cancer Med. , vol.3 , pp. 174-181
    • Fu, X.A.1    Li, M.2    Knipp, R.J.3    Nantz, M.H.4    Bousamra, M.5
  • 35
    • 70449378196 scopus 로고    scopus 로고
    • Noninvasive detection of lung cancer by analysis of exhaled breath
    • [35] Bajtarevic, A., Ager, C., Pienz, M., Klieber, M., Schwarz, K., Ligor, M., et al. Noninvasive detection of lung cancer by analysis of exhaled breath. BMC Cancer, 9, 2009, 348.
    • (2009) BMC Cancer , vol.9 , pp. 348
    • Bajtarevic, A.1    Ager, C.2    Pienz, M.3    Klieber, M.4    Schwarz, K.5    Ligor, M.6
  • 36
    • 84871549281 scopus 로고    scopus 로고
    • The analysis of volatile organic compounds biomarkers for lung cancer in exhaled breath, tissues and cell lines
    • [36] Wang, Y., Hu, Y., Wang, D., Yu, K., Wang, L., Zou, Y., et al. The analysis of volatile organic compounds biomarkers for lung cancer in exhaled breath, tissues and cell lines. Cancer Biomark. 11 (2012), 129–137.
    • (2012) Cancer Biomark. , vol.11 , pp. 129-137
    • Wang, Y.1    Hu, Y.2    Wang, D.3    Yu, K.4    Wang, L.5    Zou, Y.6
  • 37
    • 73349090616 scopus 로고    scopus 로고
    • Sniffing the unique “odor print” of non-small-cell lung cancer with gold nanoparticles
    • [37] Barash, O., Peled, N., Hirsch, F.R., Haick, H., Sniffing the unique “odor print” of non-small-cell lung cancer with gold nanoparticles. Small 5 (2009), 2618–2624.
    • (2009) Small , vol.5 , pp. 2618-2624
    • Barash, O.1    Peled, N.2    Hirsch, F.R.3    Haick, H.4
  • 38
    • 34547875741 scopus 로고    scopus 로고
    • A study of the volatile organic compounds exhaled by lung cancer cells in vitro for breath diagnosis
    • [38] Chen, X., Xu, F., Wang, Y., Pan, Y., Lu, D., Wang, P., et al. A study of the volatile organic compounds exhaled by lung cancer cells in vitro for breath diagnosis. Cancer 110 (2007), 835–844.
    • (2007) Cancer , vol.110 , pp. 835-844
    • Chen, X.1    Xu, F.2    Wang, Y.3    Pan, Y.4    Lu, D.5    Wang, P.6
  • 39
    • 84865584104 scopus 로고    scopus 로고
    • Identification of volatile lung cancer markers by gas chromatography-mass spectrometry: comparison with discrimination by canines
    • [39] Buszewski, B., Ligor, T., Jezierski, T., Wenda-Piesik, A., Walczak, M., Rudnicka, J., Identification of volatile lung cancer markers by gas chromatography-mass spectrometry: comparison with discrimination by canines. Anal. Bioanal. Chem. 404 (2012), 141–146.
    • (2012) Anal. Bioanal. Chem. , vol.404 , pp. 141-146
    • Buszewski, B.1    Ligor, T.2    Jezierski, T.3    Wenda-Piesik, A.4    Walczak, M.5    Rudnicka, J.6
  • 40
    • 84946924409 scopus 로고    scopus 로고
    • The lung cancer breath signature: a comparative analysis of exhaled breath and air sampled from inside the lungs
    • [40] Capuano, R., Santonico, M., Pennazza, G., Ghezzi, S., Martinelli, E., Roscioni, C., et al. The lung cancer breath signature: a comparative analysis of exhaled breath and air sampled from inside the lungs. Sci. Rep., 5, 2015, 16491.
    • (2015) Sci. Rep. , vol.5 , pp. 16491
    • Capuano, R.1    Santonico, M.2    Pennazza, G.3    Ghezzi, S.4    Martinelli, E.5    Roscioni, C.6
  • 41
    • 77951227876 scopus 로고    scopus 로고
    • Breath gas aldehydes as biomarkers of lung cancer
    • [41] Fuchs, P., Loeseken, C., Schubert, J.K., Miekisch, W., Breath gas aldehydes as biomarkers of lung cancer. Int. J. Cancer 126 (2010), 2663–2670.
    • (2010) Int. J. Cancer , vol.126 , pp. 2663-2670
    • Fuchs, P.1    Loeseken, C.2    Schubert, J.K.3    Miekisch, W.4
  • 42
    • 77956490793 scopus 로고    scopus 로고
    • Breath biomarkers for lung cancer detection and assessment of smoking related effects-confounding variables, influence of normalization and statistical algorithms
    • [42] Kischkel, S., Miekisch, W., Sawacki, A., Straker, E.M., Trefz, P., Amann, A., Schubert, J.K., Breath biomarkers for lung cancer detection and assessment of smoking related effects-confounding variables, influence of normalization and statistical algorithms. Clin. Chim. Acta 411 (2010), 1637–1644.
    • (2010) Clin. Chim. Acta , vol.411 , pp. 1637-1644
    • Kischkel, S.1    Miekisch, W.2    Sawacki, A.3    Straker, E.M.4    Trefz, P.5    Amann, A.6    Schubert, J.K.7
  • 43
    • 67649158483 scopus 로고    scopus 로고
    • Determination of volatile organic compounds in exhaled breath of patients with lung cancer using solid phase microextraction and gas chromatography mass spectrometry
    • [43] Ligor, M., Ligor, T., Bajtarevic, A., Ager, C., Pienz, M., Klieber, M., et al. Determination of volatile organic compounds in exhaled breath of patients with lung cancer using solid phase microextraction and gas chromatography mass spectrometry. Clin. Chem. Lab. Med. 47 (2009), 550–560.
    • (2009) Clin. Chem. Lab. Med. , vol.47 , pp. 550-560
    • Ligor, M.1    Ligor, T.2    Bajtarevic, A.3    Ager, C.4    Pienz, M.5    Klieber, M.6
  • 45
    • 0033526615 scopus 로고    scopus 로고
    • Volatile organic compounds in breath as markers of lung cancer: a cross-sectional study
    • [45] Phillips, M., Gleeson, K., Hughes, J.M., Greenberg, J., Cataneo, R.N., Baker, L., McVay, W.P., Volatile organic compounds in breath as markers of lung cancer: a cross-sectional study. Lancet 353 (1999), 1930–1933.
    • (1999) Lancet , vol.353 , pp. 1930-1933
    • Phillips, M.1    Gleeson, K.2    Hughes, J.M.3    Greenberg, J.4    Cataneo, R.N.5    Baker, L.6    McVay, W.P.7
  • 46
    • 26244435817 scopus 로고    scopus 로고
    • Exhaled volatile organic compounds in patients with non-small cell lung cancer: cross sectional and nested short-term follow-up study
    • [46] Poli, D., Carbognani, P., Corradi, M., Goldoni, M., Acampa, O., Balbi, B., et al. Exhaled volatile organic compounds in patients with non-small cell lung cancer: cross sectional and nested short-term follow-up study. Respir. Res., 6, 2005, 71.
    • (2005) Respir. Res. , vol.6 , pp. 71
    • Poli, D.1    Carbognani, P.2    Corradi, M.3    Goldoni, M.4    Acampa, O.5    Balbi, B.6
  • 48
    • 0023797363 scopus 로고
    • Analysis of lung air from patients with bronchogenic carcinoma and controls using gas chromatography-mass spectrometry
    • [48] Preti, G., Labows, J.N., Kostelc, J.G., Aldinger, S., Daniele, R., Analysis of lung air from patients with bronchogenic carcinoma and controls using gas chromatography-mass spectrometry. J. Chromatogr. B Biomed. Sci. Appl. 432 (1988), 1–11.
    • (1988) J. Chromatogr. B Biomed. Sci. Appl. , vol.432 , pp. 1-11
    • Preti, G.1    Labows, J.N.2    Kostelc, J.G.3    Aldinger, S.4    Daniele, R.5
  • 49
    • 80555122916 scopus 로고    scopus 로고
    • Determination of volatile organic compounds as biomarkers of lung cancer by SPME-GC-TOF/MS and chemometrics
    • [49] Rudnicka, J., Kowalkowski, T., Ligor, T., Buszewski, B., Determination of volatile organic compounds as biomarkers of lung cancer by SPME-GC-TOF/MS and chemometrics. J. Chromatogr. B Anal. Technol. Biomed. Life Sci. 879 (2011), 3360–3366.
    • (2011) J. Chromatogr. B Anal. Technol. Biomed. Life Sci. , vol.879 , pp. 3360-3366
    • Rudnicka, J.1    Kowalkowski, T.2    Ligor, T.3    Buszewski, B.4
  • 50
    • 84861757445 scopus 로고    scopus 로고
    • In situ detection of lung cancer volatile fingerprints using bronchoscopic air-sampling
    • [50] Santonico, M., Lucantoni, G., Pennazza, G., Capuano, R., Galluccio, G., Roscioni, C., et al. In situ detection of lung cancer volatile fingerprints using bronchoscopic air-sampling. Lung Cancer 77 (2012), 46–50.
    • (2012) Lung Cancer , vol.77 , pp. 46-50
    • Santonico, M.1    Lucantoni, G.2    Pennazza, G.3    Capuano, R.4    Galluccio, G.5    Roscioni, C.6
  • 51
    • 72449164474 scopus 로고    scopus 로고
    • Quantitative breath analysis of volatile organic compounds of lung cancer patients
    • [51] Song, G., Qin, T., Liu, H., Xu, G.B., Pan, Y.Y., Xiong, F.X., et al. Quantitative breath analysis of volatile organic compounds of lung cancer patients. Lung Cancer 67 (2010), 227–231.
    • (2010) Lung Cancer , vol.67 , pp. 227-231
    • Song, G.1    Qin, T.2    Liu, H.3    Xu, G.B.4    Pan, Y.Y.5    Xiong, F.X.6
  • 52
    • 34247866471 scopus 로고    scopus 로고
    • An off-line breath sampling and analysis method suitable for large screening studies
    • [52] Steeghs, M.M.L., Cristescu, S.M., Munnik, P., Zanen, P., Harren, F.J.M., An off-line breath sampling and analysis method suitable for large screening studies. Physiol. Meas. 28 (2007), 503–514.
    • (2007) Physiol. Meas. , vol.28 , pp. 503-514
    • Steeghs, M.M.L.1    Cristescu, S.M.2    Munnik, P.3    Zanen, P.4    Harren, F.J.M.5
  • 54
    • 83155176926 scopus 로고    scopus 로고
    • The application of statistical methods using VOCs to identify patients with lung cancer
    • [54] Ulanowska, A., Kowalkowski, T., Trawińska, E., Buszewski, B., The application of statistical methods using VOCs to identify patients with lung cancer. J. Breath Res., 5, 2011, 046008.
    • (2011) J. Breath Res. , vol.5 , pp. 046008
    • Ulanowska, A.1    Kowalkowski, T.2    Trawińska, E.3    Buszewski, B.4
  • 55
    • 4143053648 scopus 로고    scopus 로고
    • Diagnostic potential of breath analysis—focus on volatile organic compounds
    • [55] Miekisch, W., Schubert, J.K., Noeldge-Schomburg, G.F.E., Diagnostic potential of breath analysis—focus on volatile organic compounds. Clin. Chim. Acta 347 (2004), 25–39.
    • (2004) Clin. Chim. Acta , vol.347 , pp. 25-39
    • Miekisch, W.1    Schubert, J.K.2    Noeldge-Schomburg, G.F.E.3
  • 56
    • 79952902922 scopus 로고    scopus 로고
    • Methodological issues of sample collection and analysis of exhaled breath
    • I. Horvath J. de Jongste European Respiratory Society
    • [56] Amann, A., Miekisch, W., Pleil, J., Risby, T., Schubert, J., Methodological issues of sample collection and analysis of exhaled breath. Horvath, I., de Jongste, J., (eds.) Exhaled Biomarkers, 2010, European Respiratory Society, 96–114.
    • (2010) Exhaled Biomarkers , pp. 96-114
    • Amann, A.1    Miekisch, W.2    Pleil, J.3    Risby, T.4    Schubert, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.