Innovative combination of QuEChERS extraction with on-line solid-phase extract purification and pre-concentration, followed by liquid chromatography-tandem mass spectrometry for the determination of non-steroidal anti-inflammatory drugs and their metabolites in sewage sludge

Analytica Chimica Acta

Volumn 935, Issue , 2016, Pages 269-281

  Rossini, D ^a,b   Ciofi, L ^a   Ancillotti, C ^a   Checchini, L ^a   Bruzzoniti, M C ^b   Rivoira, L ^b   Fibbi, D ^c   Orlandini, S ^a   Del Bubba, M ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITY OF TURIN   (Italy)

^c GIDA SpA   (Italy)

Author keywords

Drug metabolites; Liquid chromatography tandem mass spectrometry; Non steroidal anti inflammatory drugs; QuEChERS; Sewage sludge; Solid phase pre concentration and purification

Indexed keywords

BIOMOLECULES; CHROMATOGRAPHY; DRUG PRODUCTS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLITES; POLYMERS; PURIFICATION; SALICYLIC ACID; SEWAGE SLUDGE; SILICA; SILICA GEL; SPECTROMETRY;

DRUG METABOLITES; LIQUID CHROMATOGRAPHY-TANDEM MASS SPECTROMETRY; NON-STEROIDAL ANTI-INFLAMMATORY DRUGS; PRE-CONCENTRATION; QUECHERS;

EXTRACTION;

1 HYDROXYIBUPROFEN; 2 HYDROXYIBUPROFEN; 3 HYDROXYIBUPROFEN; 4' HYDROXYDICLOFENAC; ACETONITRILE; ACETYLSALICYLIC ACID; BIPHENYL; CHEMICAL COMPOUND; DICLOFENAC; DRUG METABOLITE; FENBUFEN; FLURBIPROFEN; IBUPROFEN; KETOPROFEN; NAPROXEN; NONSTEROID ANTIINFLAMMATORY AGENT; O DESMETHYLNAPROXEN; OCTADECYL; PENTAFLUOROPHENYL; PHENYLHEXYL; SALICYLIC ACID; SILICA GEL; UNCLASSIFIED DRUG; WATER;

ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DESORPTION; DILUTION; DRUG DETERMINATION; ELUTION; EXTRACTION; FREEZE DRYING; LIQUID CHROMATOGRAPHY; MEASUREMENT PRECISION; PRIORITY JOURNAL; PROCESS OPTIMIZATION; PURIFICATION; QUICK, EASY, CHEAP, EFFECTIVE, RUGGED, AND SAFE EXTRACTION; ROOM TEMPERATURE; SENSITIVITY ANALYSIS; SLUDGE; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY; ANALYSIS; METABOLISM; SEWAGE;

ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CHROMATOGRAPHY, LIQUID; SEWAGE; SOLID PHASE EXTRACTION; TANDEM MASS SPECTROMETRY;

EID: 84977636538     PISSN: 00032670     EISSN: 18734324     Source Type: Journal    
DOI: 10.1016/j.aca.2016.06.023     Document Type: Article

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