Diffusion-weighted imaging: Apparent diffusion coefficient histogram analysis for detecting pathologic complete response to chemoradiotherapy in locally advanced rectal cancer

Journal of Magnetic Resonance Imaging

Volumn 44, Issue 1, 2016, Pages 212-220

  Choi, Moon Hyung ^a   Oh, Soon Nam ^a   Rha, Sung Eun ^a   Choi, Joon Il ^a   Lee, Sung Hak ^a   Jang, Hong Seok ^a   Kim, Jun Gi ^a   Grimm, Robert ^b   Son, Yohan ^c  

^a The Catholic University of Korea   (South Korea)

^b SIEMENS AG   (Germany)

^c SIEMENS Healthcare   (South Korea)

Author keywords

apparent diffusion coefficient (ADC); chemoradiotherapy; histogram; rectal cancer

Indexed keywords

FLUOROURACIL; FOLINIC ACID;

ADJUVANT CHEMORADIOTHERAPY; ADULT; ADVANCED CANCER; AGED; APPARENT DIFFUSION COEFFICIENT; AREA UNDER THE CURVE; ARTICLE; CANCER GRADING; CANCER LOCALIZATION; CANCER STAGING; CANCER SURGERY; DIFFUSION COEFFICIENT; DIFFUSION WEIGHTED IMAGING; FEMALE; HISTOGRAM; HUMAN; MAJOR CLINICAL STUDY; MALE; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; PRIORITY JOURNAL; RADIATION DOSE; RECEIVER OPERATING CHARACTERISTIC; RECTUM CANCER; TREATMENT RESPONSE;

EID: 84977615403     PISSN: 10531807     EISSN: 15222586     Source Type: Journal    
DOI: 10.1002/jmri.25117     Document Type: Article

References (29)

1. Camma C, Giunta M, Fiorica F, Pagliaro L, Craxi A, Cottone M. Preoperative radiotherapy for resectable rectal cancer: A meta-analysis. JAMA 2000;284:1008–1015.
2. Garcia-Aguilar J, Hernandez de Anda E, Sirivongs P, et al. A pathologic complete response to preoperative chemoradiation is associated with lower local recurrence and improved survival in rectal cancer patients treated by mesorectal excision. Dis Colon Rectum 2003;46:298–304.
3. Gerard A, Buyse M, Nordlinger B, et al. Preoperative radiotherapy as adjuvant treatment in rectal cancer. Final results of a randomized study of the European Organization for Research and Treatment of Cancer (EORTC). Ann Surg 1988;208:606–614.
4. Theodoropoulos G, Wise WE, Padmanabhan A, et al. T-level downstaging and complete pathologic response after preoperative chemoradiation for advanced rectal cancer result in decreased recurrence and improved disease-free survival. Dis Colon Rectum 2002;45:895–903.
5. Habr-Gama A, Perez RO, Nadalin W, et al Operative versus nonoperative treatment for stage 0 distal rectal cancer following chemoradiation therapy: long-term results. Ann Surg 2004;240:711–717; discussion 717–718.
6. Beets-Tan RG. MRI in rectal cancer: the T stage and circumferential resection margin. Colorectal Dis 2003;5:392–395.
7. Beets-Tan RG, Beets GL. Rectal cancer: review with emphasis on MR imaging. Radiology 2004;232:335–346.
8. Pierredon-Foulongne MA, Nougaret S, Bibeau F, et al. Utility of reassessment after neoadjuvant therapy and difficulties in interpretation. Diagn Interv Imaging 2014;95:495–503.
9. Allen SD, Padhani AR, Dzik-Jurasz AS, Glynne-Jones R. Rectal carcinoma: MRI with histologic correlation before and after chemoradiation therapy. AJR Am J Roentgenol 2007;188:442–451.
10. De Nardi P, Carvello M. How reliable is current imaging in restaging rectal cancer after neoadjuvant therapy? World J Gastroenterol 2013;19:5964–5972.
11. Kuo L-J, Chern M-C, Tsou M-H, et al. Interpretation of magnetic resonance imaging for locally advanced rectal carcinoma after preoperative chemoradiation therapy. Dis Colon Rectum 2005;48:23–28.
12. Rao SX, Zeng MS, Chen CZ, et al. The value of diffusion-weighted imaging in combination with T2-weighted imaging for rectal cancer detection. Eur J Radiol 2008;65:299–303.
13. van der Paardt MP, Zagers MB, Beets-Tan RG, Stoker J, Bipat S. Patients who undergo preoperative chemoradiotherapy for locally advanced rectal cancer restaged by using diagnostic MR imaging: a systematic review and meta-analysis. Radiology 2013;269:101–112.
14. Kim SH, Lee JM, Hong SH, et al. Locally advanced rectal cancer: added value of diffusion-weighted MR imaging in the evaluation of tumor response to neoadjuvant chemo- and radiation therapy. Radiology 2009;253:116–125.
15. Kim SH, Lee JY, Lee JM, Han JK, Choi BI. Apparent diffusion coefficient for evaluating tumour response to neoadjuvant chemoradiation therapy for locally advanced rectal cancer. Eur Radiol 2011;21:987–995.
16. Park MJ, Kim SH, Lee SJ, Jang KM, Rhim H. Locally advanced rectal cancer: added value of diffusion-weighted MR imaging for predicting tumor clearance of the mesorectal fascia after neoadjuvant chemotherapy and radiation therapy. Radiology 2011;260:771–780.
17. Hotker AM, Garcia-Aguilar J, Gollub MJ. Multiparametric MRI of rectal cancer in the assessment of response to therapy: a systematic review. Dis Colon Rectum 2014;57:790–799.
18. Lambregts DM, Beets GL, Maas M, et al. Tumour ADC measurements in rectal cancer: effect of ROI methods on ADC values and interobserver variability. Eur Radiol 2011;21:2567–2574.
19. Cho SH, Kim GC, Jang YJ, et al. Locally advanced rectal cancer: post-chemoradiotherapy ADC histogram analysis for predicting a complete response. Acta Radiol 2014;56:1042–1050.
20. Nasu K, Kuroki Y, Minami M. Diffusion-weighted imaging findings of mucinous carcinoma arising in the ano-rectal region: comparison of apparent diffusion coefficient with that of tubular adenocarcinoma. Jpn J Radiol 2012;30:120–127.
21. Dworak O, Keilholz L, Hoffmann A. Pathological features of rectal cancer after preoperative radiochemotherapy. Int J Colorectal Dis 1997;12:19–23.
22. Park MY, Byun JY. Understanding the mathematics involved in calculating apparent diffusion coefficient maps. Am J Roentgenol 2012;199:W784–W784.
23. Just N. Improving tumour heterogeneity MRI assessment with histograms. Br J Cancer 2014;111:2205–2213.
24. Cai PQ, Wu YP, An X, et al. Simple measurements on diffusion-weighted MR imaging for assessment of complete response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. Eur Radiol 2014;24:2962–2970.
25. Lambregts DM, Vandecaveye V, Barbaro B, et al. Diffusion-weighted MRI for selection of complete responders after chemoradiation for locally advanced rectal cancer: a multicenter study. Ann Surg Oncol 2011;18:2224–2231.
26. King AD, Chow KK, Yu KH, et al. Head and neck squamous cell carcinoma: diagnostic performance of diffusion-weighted MR imaging for the prediction of treatment response. Radiology 2013;266:531–538.
27. Kyriazi S, Collins DJ, Messiou C, et al. Metastatic ovarian and primary peritoneal cancer: assessing chemotherapy response with diffusion-weighted MR imaging—value of histogram analysis of apparent diffusion coefficients. Radiology 2011;261:182–192.
28. Engin G, Sharifov R, Gural Z, et al. Can diffusion-weighted MRI determine complete responders after neoadjuvant chemoradiation for ocally advanced rectal cancer? Diagn Interv Radiol 2012;18:574–581.
29. Genovesi D, Filippone A, Ausili Cefaro G, et al. Diffusion-weighted magnetic resonance for prediction of response after neoadjuvant chemoradiation therapy for locally advanced rectal cancer: preliminary results of a monoinstitutional prospective study. Eur J Surg Oncol 2013;39:1071–1078.