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Volumn 18, Issue 7, 2016, Pages 982-990

Molecular subgroups of adult medulloblastoma: A long-term single-institution study

Author keywords

adult medulloblastoma; histology; molecular subgroup; prognosis; survival

Indexed keywords

SONIC HEDGEHOG PROTEIN; WNT PROTEIN; BETA CATENIN; CTNNB1 PROTEIN, HUMAN; TUMOR MARKER;

EID: 84977578608     PISSN: 15228517     EISSN: 15235866     Source Type: Journal    
DOI: 10.1093/neuonc/now050     Document Type: Article
Times cited : (70)

References (29)
  • 1
    • 0032898255 scopus 로고    scopus 로고
    • Epidemiology of adult medulloblastoma
    • Giordana MT, Schiffer P, Lanotte M, et al. Epidemiology of adult medulloblastoma. Int J Cancer. 1999;80(5):689-692.
    • (1999) J Cancer , vol.80 , Issue.5 , pp. 689-692
    • Giordana, M.T.1    Schiffer, P.2    Lanotte, M.3
  • 2
    • 34247862359 scopus 로고    scopus 로고
    • Medulloblastoma: Tumorigenesis, current clinical paradigm, and efforts to improve risk stratification
    • Polkinghorn WR, Tarbell NJ. Medulloblastoma: tumorigenesis, current clinical paradigm, and efforts to improve risk stratification. Nat Clin Pract Oncol. 2007;4(5):295-304.
    • (2007) Nat Clin Pract Oncol , vol.4 , Issue.5 , pp. 295-304
    • Polkinghorn, W.R.1    Tarbell, N.J.2
  • 3
    • 33748660920 scopus 로고    scopus 로고
    • Phase III study of craniospinal radiation therapy followed by adjuvant chemotherapy for newly diagnosed average-risk medulloblastoma
    • Packer RJ, Gajjar A, Vezina G, et al. Phase III study of craniospinal radiation therapy followed by adjuvant chemotherapy for newly diagnosed average-risk medulloblastoma. J Clin Oncol. 2006; 24(25):4202-4208.
    • (2006) J Clin Oncol , vol.24 , Issue.25 , pp. 4202-4208
    • Packer, R.J.1    Gajjar, A.2    Vezina, G.3
  • 4
    • 0037842140 scopus 로고    scopus 로고
    • Results of a randomized study of preradiation chemotherapy versus radiotherapy alone for nonmetastatic medulloblastoma: The International Society of Paediatric Oncology/United Kingdom Children's Cancer Study Group PNET-3 Study
    • Taylor RE, Bailey CC, Robinson K, et al. Results of a randomized study of preradiation chemotherapy versus radiotherapy alone for nonmetastatic medulloblastoma: the International Society of Paediatric Oncology/United Kingdom Children's Cancer Study Group PNET-3 Study. J Clin Oncol. 2003;21(8):1581-1591.
    • (2003) J Clin Oncol , vol.21 , Issue.8 , pp. 1581-1591
    • Taylor, R.E.1    Bailey, C.C.2    Robinson, K.3
  • 5
    • 33749044182 scopus 로고    scopus 로고
    • Risk-adapted craniospinal radiotherapy followed by high-dose chemotherapy and stem-cell rescue in children with newly diagnosed medulloblastoma (St Jude Medulloblastoma-96): Long-term results from a prospective, multicentre trial
    • Gajjar A, ChintagumpalaM, Ashley D, et al. Risk-adapted craniospinal radiotherapy followed by high-dose chemotherapy and stem-cell rescue in children with newly diagnosed medulloblastoma (St Jude Medulloblastoma-96): long-term results from a prospective, multicentre trial. Lancet Oncol. 2006;7(10):813-820.
    • (2006) Lancet Oncol , vol.7 , Issue.10 , pp. 813-820
    • Gajjar, A.1    Chintagumpala, M.2    Ashley, D.3
  • 6
    • 84863393028 scopus 로고    scopus 로고
    • Molecular subgroups of medulloblastoma: An international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas
    • Kool M, Korshunov A, Remke M, et al. Molecular subgroups of medulloblastoma: an international meta-analysis of transcriptome, genetic aberrations, and clinical data of WNT, SHH, Group 3, and Group 4 medulloblastomas. Acta Neuropathol. 2012;123(4): 473-484.
    • (2012) Acta Neuropathol , vol.123 , Issue.4 , pp. 473-484
    • Kool, M.1    Korshunov, A.2    Remke, M.3
  • 7
    • 79955034739 scopus 로고    scopus 로고
    • Medulloblastoma comprises four distinct molecular variants
    • Northcott PA, Korshunov A, Witt H, et al. Medulloblastoma comprises four distinct molecular variants. J Clin Oncol. 2011; 29(11):1408-1414.
    • (2011) J Clin Oncol , vol.29 , Issue.11 , pp. 1408-1414
    • Northcott, P.A.1    Korshunov, A.2    Witt, H.3
  • 8
    • 79954444747 scopus 로고    scopus 로고
    • Medulloblastoma: Clinicopathological correlates of SHH, WNT, and non-SHH/WNT molecular subgroups
    • Ellison DW, Dalton J, Kocak M, et al. Medulloblastoma: clinicopathological correlates of SHH, WNT, and non-SHH/WNT molecular subgroups. Acta Neuropathol. 2011;121(3):381-396.
    • (2011) Acta Neuropathol , vol.121 , Issue.3 , pp. 381-396
    • Ellison, D.W.1    Dalton, J.2    Kocak, M.3
  • 9
    • 70349244812 scopus 로고    scopus 로고
    • Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449
    • Rudin CM, Hann CL, Laterra J, et al. Treatment of medulloblastoma with hedgehog pathway inhibitor GDC-0449. N Engl J Med. 2009; 361(12):1173-1178.
    • (2009) N Engl J Med , vol.361 , Issue.12 , pp. 1173-1178
    • Rudin, C.M.1    Hann, C.L.2    Laterra, J.3
  • 10
    • 80053980912 scopus 로고    scopus 로고
    • FSTL5 is a marker of poor prognosis in non-WNT/non-SHH medulloblastoma
    • Remke M, Hielscher T, Korshunov A, et al. FSTL5 is a marker of poor prognosis in non-WNT/non-SHH medulloblastoma. J Clin Oncol. 2011;29(29):3852-3861.
    • (2011) J Clin Oncol , vol.29 , Issue.29 , pp. 3852-3861
    • Remke, M.1    Hielscher, T.2    Korshunov, A.3
  • 11
    • 34247849227 scopus 로고    scopus 로고
    • Common strategy for adult and pediatric medulloblastoma: A multicenter series of 253 adults
    • Padovani L, Sunyach MP, Perol D, et al. Common strategy for adult and pediatric medulloblastoma: a multicenter series of 253 adults. Int J Radiat Oncol Biol Phys. 2007;68(2):433-440.
    • (2007) J Radiat Oncol Biol Phys , vol.68 , Issue.2 , pp. 433-440
    • Padovani, L.1    Sunyach, M.P.2    Perol, D.3
  • 12
    • 0035407296 scopus 로고    scopus 로고
    • Survival and recurrence factors in adult medulloblastoma: The M.D Anderson Cancer Center experience from 1978 to 1998
    • Kunschner LJ, Kuttesch J, Hess K, et al. Survival and recurrence factors in adult medulloblastoma: the M.D. Anderson Cancer Center experience from 1978 to 1998. Neuro Oncol. 2001;3(3): 167-173.
    • (2001) Neuro Oncol , vol.3 , Issue.3 , pp. 167-173
    • Kunschner, L.J.1    Kuttesch, J.2    Hess, K.3
  • 13
    • 41149088349 scopus 로고    scopus 로고
    • Survival of patients with adult medulloblastoma: A population-based study
    • Lai R. Survival of patients with adult medulloblastoma: a population-based study. Cancer. 2008;112(7):1568-1574.
    • (2008) Cancer , vol.112 , Issue.7 , pp. 1568-1574
    • Lai, R.1
  • 14
    • 77954602395 scopus 로고    scopus 로고
    • Adult and pediatric medulloblastomas are genetically distinct and require different algorithms for molecular risk stratification
    • Korshunov A, Remke M, Werft W, et al. Adult and pediatric medulloblastomas are genetically distinct and require different algorithms for molecular risk stratification. J Clin Oncol. 2010; 28(18):3054-3060.
    • (2010) J Clin Oncol , vol.28 , Issue.18 , pp. 3054-3060
    • Korshunov, A.1    Remke, M.2    Werft, W.3
  • 15
    • 34250208449 scopus 로고    scopus 로고
    • Histopathologic grading of adult medulloblastomas
    • Rodriguez FJ, Eberhart C, O'Neill BP, et al. Histopathologic grading of adult medulloblastomas. Cancer. 2007;109(12):2557-2565.
    • (2007) Cancer , vol.109 , Issue.12 , pp. 2557-2565
    • Rodriguez, F.J.1    Eberhart, C.2    O'Neill, B.P.3
  • 16
    • 84973176275 scopus 로고    scopus 로고
    • Medulloblastoma
    • In: Louis DN, Ohgaki H, Wiestler OD, et al., eds. Lyon, France: International Agency for Research on Cancer
    • Giangaspero F, Eberhart CG, Haapasalo H, et al. Medulloblastoma. In: Louis DN, Ohgaki H, Wiestler OD, et al., eds. WHO Classification of Tumours of the Central Nervous System. Lyon, France: International Agency for Research on Cancer; 2007:132-140.
    • (2007) WHO Classification of Tumours of the Central Nervous System , pp. 132-140
    • Giangaspero, F.1    Eberhart, C.G.2    Haapasalo, H.3
  • 17
    • 0014619880 scopus 로고
    • An operative staging system and a megavoltage radiotherapeutic technic [sic] for cerebellar medulloblastomas
    • Chang CH, Housepian EM, Herbert C Jr. An operative staging system and a megavoltage radiotherapeutic technic [sic] for cerebellar medulloblastomas. Radiology. 1969;93(6):1351-1359.
    • (1969) Radiology , vol.93 , Issue.6 , pp. 1351-1359
    • Chang, C.H.1    Housepian, E.M.2    Herbert C3
  • 18
    • 84899684426 scopus 로고    scopus 로고
    • Cytogenetic prognostication within medulloblastoma subgroups
    • Shih DJ, Northcott PA, Remke M, et al. Cytogenetic prognostication within medulloblastoma subgroups. J Clin Oncol. 2014;32(9): 886-896.
    • (2014) J Clin Oncol , vol.32 , Issue.9 , pp. 886-896
    • Shih, D.J.1    Northcott, P.A.2    Remke, M.3
  • 19
    • 52449119078 scopus 로고    scopus 로고
    • Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features
    • Kool M, Koster J, Bunt J, et al. Integrated genomics identifies five medulloblastoma subtypes with distinct genetic profiles, pathway signatures and clinicopathological features. PLoS One. 2008;3(8): e3088.
    • (2008) PLoS One , vol.3 , Issue.8 , pp. e3088
    • Kool, M.1    Koster, J.2    Bunt, J.3
  • 20
    • 52249104363 scopus 로고    scopus 로고
    • Characteristics and outcomes of medulloblastoma in adults
    • Ang C, Hauerstock D, Guiot MC, et al. Characteristics and outcomes of medulloblastoma in adults. Pediatr Blood Cancer. 2008;51(5):603-607.
    • (2008) Pediatr Blood Cancer , vol.51 , Issue.5 , pp. 603-607
    • Ang, C.1    Hauerstock, D.2    Guiot, M.C.3
  • 21
    • 79960119129 scopus 로고    scopus 로고
    • Adult medulloblastoma comprises three major molecular variants
    • Remke M, Hielscher T, Northcott PA, et al. Adult medulloblastoma comprises three major molecular variants. J Clin Oncol. 2011; 29(19):2717-2723.
    • (2011) J Clin Oncol , vol.29 , Issue.19 , pp. 2717-2723
    • Remke, M.1    Hielscher, T.2    Northcott, P.A.3
  • 22
    • 79951910309 scopus 로고    scopus 로고
    • Survival and prognostic factors of early childhood medulloblastoma: An international meta-analysis
    • Rutkowski S, von Hoff K, Emser A, et al. Survival and prognostic factors of early childhood medulloblastoma: an international meta-analysis. J Clin Oncol. 2010;28(33):4961-4968.
    • (2010) J Clin Oncol , vol.28 , Issue.33 , pp. 4961-4968
    • Rutkowski, S.1    Von Hoff, K.2    Emser, A.3
  • 23
    • 0037080303 scopus 로고    scopus 로고
    • Histopathologic grading of medulloblastomas: A Pediatric Oncology Group study
    • Eberhart CG, Kepner JL, Goldthwaite PT, et al. Histopathologic grading of medulloblastomas: a Pediatric Oncology Group study. Cancer. 2002;94(2):552-560.
    • (2002) Cancer , vol.94 , Issue.2 , pp. 552-560
    • Eberhart, C.G.1    Kepner, J.L.2    Goldthwaite, P.T.3
  • 24
    • 20044371594 scopus 로고    scopus 로고
    • Treatment of early childhood medulloblastoma by postoperative chemotherapy alone
    • Rutkowski S, Bode U, Deinlein F, et al. Treatment of early childhood medulloblastoma by postoperative chemotherapy alone. N Engl J Med. 2005;352(10):978-986.
    • (2005) N Engl J Med , vol.352 , Issue.10 , pp. 978-986
    • Rutkowski, S.1    Bode, U.2    Deinlein, F.3
  • 25
    • 0026663357 scopus 로고
    • Large-cell medulloblastomas A distinct variant with highly aggressive behavior
    • Giangaspero F, Rigobello L, Badiali M, et al. Large-cell medulloblastomas. A distinct variant with highly aggressive behavior. Am J Surg Pathol. 1992;16:687-693.
    • (1992) Am J Surg Pathol , vol.16 , pp. 687-693
    • Giangaspero, F.1    Rigobello, L.2    Badiali, M.3
  • 26
    • 0033791188 scopus 로고    scopus 로고
    • Large cell/anaplastic" medulloblastomas: A Pediatric Oncology Group study
    • Brown HG, Kepner JL, Perlman EJ, et al. "Large cell/anaplastic" medulloblastomas: a Pediatric Oncology Group study. J Neuropathol Exp Neurol. 2000;59:857-865.
    • (2000) J Neuropathol Exp Neurol , vol.59 , pp. 857-865
    • Brown, H.G.1    Kepner, J.L.2    Perlman, E.J.3
  • 27
    • 77952198779 scopus 로고    scopus 로고
    • High-dose carboplatin, thiotepa, and etoposide with autologous stem cell rescue for patients with previously irradiated recurrent medulloblastoma
    • Dunkel IJ, Gardner SL, Garvin JH Jr, et al. High-dose carboplatin, thiotepa, and etoposide with autologous stem cell rescue for patients with previously irradiated recurrent medulloblastoma. Neuro Oncol. 2010;12(3):297-303.
    • (2010) Neuro Oncol , vol.12 , Issue.3 , pp. 297-303
    • Dunkel, I.J.1    Gardner, S.L.2    Garvin, J.H.3
  • 28
    • 0028102963 scopus 로고
    • Multivariate analysis of prognostic factors in adult patients with medulloblastoma Retrospective study of 156 patients
    • Carrie C, Lasset C, Alapetite C, et al. Multivariate analysis of prognostic factors in adult patients with medulloblastoma. Retrospective study of 156 patients. Cancer. 1994;74(8):2352-2360.
    • (1994) Cancer , vol.74 , Issue.8 , pp. 2352-2360
    • Carrie, C.1    Lasset, C.2    Alapetite, C.3
  • 29
    • 35648929959 scopus 로고    scopus 로고
    • Long-term results of a prospective study on the treatment of medulloblastoma in adults
    • Brandes AA, Franceschi E, Tosoni A, et al. Long-term results of a prospective study on the treatment of medulloblastoma in adults. Cancer. 2007;110(9):2035-2041.
    • (2007) Cancer , vol.110 , Issue.9 , pp. 2035-2041
    • Brandes, A.A.1    Franceschi, E.2    Tosoni, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.