-
2
-
-
55949136562
-
Roles of the EZH2 histone methyltransferase in cancer epigenetics
-
Simon JA and Lange CA: Roles of the EZH2 histone methyltransferase in cancer epigenetics. Mutat Res 647: 21-29, 2008.
-
(2008)
Mutat Res
, vol.647
, pp. 21-29
-
-
Simon, J.A.1
Lange, C.A.2
-
3
-
-
32844459336
-
The Polycomb group protein EZH2 directly controls DNA methylation
-
Vire E, Brenner C, Deplus R, Blanchon L, Fraga M, Didelot C, Morey L, Van Eynde A, Bernard D, Vanderwinden JM, et al: The Polycomb group protein EZH2 directly controls DNA methylation. Nature 439: 871-874, 2006.
-
(2006)
Nature
, vol.439
, pp. 871-874
-
-
Vire, E.1
Brenner, C.2
Deplus, R.3
Blanchon, L.4
Fraga, M.5
Didelot, C.6
Morey, L.7
Van Eynde, A.8
Bernard, D.9
Vanderwinden, J.M.10
-
4
-
-
33646865180
-
Control of developmental regulators by polycomb in human embryonic stem cells
-
Lee TI, Jenner RG, Boyer LA, Guenther MG, Levine SS, Kumar RM, et al: Control of developmental regulators by polycomb in human embryonic stem cells. Cell 125: 301-313, 2006.
-
(2006)
Cell
, vol.125
, pp. 301-313
-
-
Lee, T.I.1
Jenner, R.G.2
Boyer, L.A.3
Guenther, M.G.4
Levine, S.S.5
Kumar, R.M.6
-
5
-
-
62149122634
-
Ezh2 orchestrates gene expression for the stepwise differentiation of tissue-specific stem cells
-
Ezhkova E, Pasolli HA, Parker JS, Stokes N, Su IH, Hannon G, Tarakhovsky A and Fuchs E: Ezh2 orchestrates gene expression for the stepwise differentiation of tissue-specific stem cells. Cell 136: 1122-1135, 2009.
-
(2009)
Cell
, vol.136
, pp. 1122-1135
-
-
Ezhkova, E.1
Pasolli, H.A.2
Parker, J.S.3
Stokes, N.4
Su, I.H.5
Hannon, G.6
Tarakhovsky, A.7
Fuchs, E.8
-
6
-
-
84889263268
-
Role of EZH2 in the growth of prostate cancer stem cells isolated from LNCaP cells
-
Li KQ, Liu C, Zhou BF, Bi L, Huang H, Lin T and Xu K: Role of EZH2 in the growth of prostate cancer stem cells isolated from LNCaP cells. Int J Mol Sci 14: 11981-11993, 2013.
-
(2013)
Int J Mol Sci
, vol.14
, pp. 11981-11993
-
-
Li, K.Q.1
Liu, C.2
Zhou, B.F.3
Bi, L.4
Huang, H.5
Lin, T.6
Xu, K.7
-
7
-
-
79951825513
-
Ovarian cancer stem cell-like side populations are enriched following chemotherapy and overexpress EZH2
-
Rizzo S, Hersey JM, Mellor P, Dai W, Santos-Silva A, Liber D, Luk L, Titley I, Carden CP, Box G, Hudson DL, Kaye SB and Brown R: Ovarian cancer stem cell-like side populations are enriched following chemotherapy and overexpress EZH2. Mol Cancer Ther. 10: 325-335, 2011.
-
(2011)
Mol Cancer Ther.
, vol.10
, pp. 325-335
-
-
Rizzo, S.1
Hersey, J.M.2
Mellor, P.3
Dai, W.4
Santos-Silva, A.5
Liber, D.6
Luk, L.7
Titley, I.8
Carden, C.P.9
Box, G.10
Hudson, D.L.11
Kaye, S.B.12
Brown, R.13
-
9
-
-
84862804208
-
CD24: A novel cancer biomarker in laryngeal squamous cell carcinoma
-
Shi Y, Gong HL, Zhou L, Tian J and Wang Y: CD24: A novel cancer biomarker in laryngeal squamous cell carcinoma. ORL J Otorhinolaryngol Relat Spec 74: 78-85, 2012.
-
(2012)
ORL J Otorhinolaryngol Relat Spec
, vol.74
, pp. 78-85
-
-
Shi, Y.1
Gong, H.L.2
Zhou, L.3
Tian, J.4
Wang, Y.5
-
10
-
-
84893664613
-
Role of EZH2 in oral squamous cell carcinoma carcinogenesis
-
Zhao LB, Yu Y, Wu J, Bai J, Zhao Y, Li C, Sun W and Wang X: Role of EZH2 in oral squamous cell carcinoma carcinogenesis. Gene 537: 197-202, 2014.
-
(2014)
Gene
, vol.537
, pp. 197-202
-
-
Zhao, L.B.1
Yu, Y.2
Wu, J.3
Bai, J.4
Zhao, Y.5
Li, C.6
Sun, W.7
Wang, X.8
-
11
-
-
84923266542
-
Improvements in survival and disparities for advanced-staged laryngeal cancer
-
Blake JL, Runhua S, Vikas M, Glenn M, Federico A and Cherie-Ann ON: Improvements in survival and disparities for advanced-staged laryngeal cancer. JAMA Otolaryngol Head Neck Surg 141: 169-173, 2015.
-
(2015)
JAMA Otolaryngol Head Neck Surg
, vol.141
, pp. 169-173
-
-
Blake, J.L.1
Runhua, S.2
Vikas, M.3
Glenn, M.4
Federico, A.5
Cherie-Ann, O.N.6
-
12
-
-
33344469959
-
The polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion
-
Kamminga LM, Bystrykh LV, de Boer A, Houwer S, Douma J, Weersing E, Dontje B and de Haan G: The polycomb group gene Ezh2 prevents hematopoietic stem cell exhaustion. Blood 107: 2170-2179, 2006.
-
(2006)
Blood
, vol.107
, pp. 2170-2179
-
-
Kamminga, L.M.1
Bystrykh, L.V.2
de Boer, A.3
Houwer, S.4
Douma, J.5
Weersing, E.6
Dontje, B.7
de Haan, G.8
-
13
-
-
79955459714
-
Polycomb EZH2 controls self-renewal and safeguards the transcriptional identity of skeletal muscle stem cells
-
Juan AH, Derfoul A, Feng X, Ryall JG, Dell’Orso S, Pasut A, Zare H, Simone JM, Rudnicki MA and Sartorelli V: Polycomb EZH2 controls self-renewal and safeguards the transcriptional identity of skeletal muscle stem cells. Gene Dev 25: 789-794, 2011.
-
(2011)
Gene Dev
, vol.25
, pp. 789-794
-
-
Juan, A.H.1
Derfoul, A.2
Feng, X.3
Ryall, J.G.4
Dell’Orso, S.5
Pasut, A.6
Zare, H.7
Simone, J.M.8
Rudnicki, M.A.9
Sartorelli, V.10
-
14
-
-
56249129313
-
Differentiation of neural stem cells into oligodendrocytes: Involvement of the polycomb group protein Ezh2
-
Sher F, Rössler R, Brouwer N, Balasubramaniyan V, Boddeke E and Copray S: Differentiation of neural stem cells into oligodendrocytes: Involvement of the polycomb group protein Ezh2. Stem Cells 26: 2875-2883, 2008.
-
(2008)
Stem Cells
, vol.26
, pp. 2875-2883
-
-
Sher, F.1
Rössler, R.2
Brouwer, N.3
Balasubramaniyan, V.4
Boddeke, E.5
Copray, S.6
-
15
-
-
82555176159
-
Polycomb group protein EZH2 is frequently expressed in inflammatory breast cancer and is predictive of worse clinical outcome
-
Gong Y, Huo L, Liu P, Sneige N, Sun X, Ueno NT, Lucci A, Buchholz TA, Valero V and Cristofanilli M: Polycomb group protein EZH2 is frequently expressed in inflammatory breast cancer and is predictive of worse clinical outcome. Cancer 117: 5476-5484, 2011.
-
(2011)
Cancer
, vol.117
, pp. 5476-5484
-
-
Gong, Y.1
Huo, L.2
Liu, P.3
Sneige, N.4
Sun, X.5
Ueno, N.T.6
Lucci, A.7
Buchholz, T.A.8
Valero, V.9
Cristofanilli, M.10
-
16
-
-
84878548632
-
Quantitative analysis of EZH2 expression and its correlations with lung cancer patients’ clinical pathological characteristics
-
Wan L, Li X, Shen H and Bai X: Quantitative analysis of EZH2 expression and its correlations with lung cancer patients’ clinical pathological characteristics. Clin Transl Oncol 15: 132-138, 2013.
-
(2013)
Clin Transl Oncol
, vol.15
, pp. 132-138
-
-
Wan, L.1
Li, X.2
Shen, H.3
Bai, X.4
-
17
-
-
77957282672
-
Enhancer of zeste homolog 2 (EZH2) expression is an independent prognostic factor in renal cell carcinoma
-
Wagener N, Macher-Goeppinger S, Pritsch M, Hüsing J, Hoppe-Seyler K, Schirmacher P, Pfitzenmaier J, Haferkamp A, Hoppe-Seyler F and Hohenfellner M: Enhancer of zeste homolog 2 (EZH2) expression is an independent prognostic factor in renal cell carcinoma. Bmc Cancer 10: 524, 2010.
-
(2010)
Bmc Cancer
, vol.10
, pp. 524
-
-
Wagener, N.1
Macher-Goeppinger, S.2
Pritsch, M.3
Hüsing, J.4
Hoppe-Seyler, K.5
Schirmacher, P.6
Pfitzenmaier, J.7
Haferkamp, A.8
Hoppe-Seyler, F.9
Hohenfellner, M.10
-
18
-
-
33644822360
-
EZH2 expression is associated with high proliferation rate and aggressive tumor subgroups in cutaneous melanoma and cancers of the endometrium, prostate and breast
-
Bachmann IM, Halvorsen OJ, Collett K, Stefansson IM, Straume O, Haukaas SA, Salvesen HB, Otte AP, et al: EZH2 expression is associated with high proliferation rate and aggressive tumor subgroups in cutaneous melanoma and cancers of the endometrium, prostate and breast. J Clin Oncol 24: 268-273, 2006.
-
(2006)
J Clin Oncol
, vol.24
, pp. 268-273
-
-
Bachmann, I.M.1
Halvorsen, O.J.2
Collett, K.3
Stefansson, I.M.4
Straume, O.5
Haukaas, S.A.6
Salvesen, H.B.7
Otte, A.P.8
-
19
-
-
57549115637
-
High expression of EZH2 is associated with tumor proliferation and prognosis in human oral squamous cell carcinomas
-
Kidani K, Osaki M, Tamura T, Yamaga K, Shomori K, Ryoke K and Ito H: High expression of EZH2 is associated with tumor proliferation and prognosis in human oral squamous cell carcinomas. Oral Oncol 45: 39-46, 2009.
-
(2009)
Oral Oncol
, vol.45
, pp. 39-46
-
-
Kidani, K.1
Osaki, M.2
Tamura, T.3
Yamaga, K.4
Shomori, K.5
Ryoke, K.6
Ito, H.7
-
20
-
-
79957552560
-
Enhancer of Zeste homolog 2 (EZH2) is overexpressed in recurrent nasopharyngeal carcinoma and is regulated by miR-26a, miR-101 and miR-98
-
Alajez NM, Shi W, Hui AB, Bruce J, Lenarduzzi M, Ito E, Yue S, O’Sullivan B and Liu F: Enhancer of Zeste homolog 2 (EZH2) is overexpressed in recurrent nasopharyngeal carcinoma and is regulated by miR-26a, miR-101 and miR-98. Cell Death Dis 1: e85, 2010.
-
(2010)
Cell Death Dis
, vol.1
-
-
Alajez, N.M.1
Shi, W.2
Hui, A.B.3
Bruce, J.4
Lenarduzzi, M.5
Ito, E.6
Yue, S.7
O’Sullivan, B.8
Liu, F.9
-
21
-
-
77956277833
-
EZH2 supports ovarian carcinoma cell invasion and/or metastasis via regulation of TGF-beta1 and is a predictor of outcome in ovarian carcinoma patients
-
Rao ZY, Cai MY, Yang GF, He LR, Mai SJ, Hua WF, Liao YJ, Deng HX, Chen YC, Guan XY, et al: EZH2 supports ovarian carcinoma cell invasion and/or metastasis via regulation of TGF-beta1 and is a predictor of outcome in ovarian carcinoma patients. Carcinogenesis 31: 1576-1583, 2010.
-
(2010)
Carcinogenesis
, vol.31
, pp. 1576-1583
-
-
Rao, Z.Y.1
Cai, M.Y.2
Yang, G.F.3
He, L.R.4
Mai, S.J.5
Hua, W.F.6
Liao, Y.J.7
Deng, H.X.8
Chen, Y.C.9
Guan, X.Y.10
-
22
-
-
84856533341
-
EZH2 supports nasopharyngeal carcinoma cell aggressiveness by forming a co-repressor complex with HDAC1/HDAC2 and Snail to inhibit E-cadherin
-
Tong ZT, Cai MY, Wang XG, Kong LL, Mai SJ, Liu YH, Zhang HB, Liao YJ, Zheng F, Zhu W, et al: EZH2 supports nasopharyngeal carcinoma cell aggressiveness by forming a co-repressor complex with HDAC1/HDAC2 and Snail to inhibit E-cadherin. Oncogene 31: 583-594, 2012.
-
(2012)
Oncogene
, vol.31
, pp. 583-594
-
-
Tong, Z.T.1
Cai, M.Y.2
Wang, X.G.3
Kong, L.L.4
Mai, S.J.5
Liu, Y.H.6
Zhang, H.B.7
Liao, Y.J.8
Zheng, F.9
Zhu, W.10
-
23
-
-
84867987203
-
EZH2 inhibition: Targeting the crossroad of tumor invasion and angiogenesis
-
Crea F, Fornaro L, Bocci G, Sun L, Farrar WL, Falcone A and Danesi R: EZH2 inhibition: Targeting the crossroad of tumor invasion and angiogenesis. Cancer Metast Rev 31: 753-761, 2012.
-
(2012)
Cancer Metast Rev
, vol.31
, pp. 753-761
-
-
Crea, F.1
Fornaro, L.2
Bocci, G.3
Sun, L.4
Farrar, W.L.5
Falcone, A.6
Danesi, R.7
-
24
-
-
79958029138
-
BMI1 promotes the progression of laryngeal squamous cell carcinoma
-
Chen H, Zhou L, Wan G, Dou T and Tian J: BMI1 promotes the progression of laryngeal squamous cell carcinoma. Oral Oncol 47: 472-481, 2011.
-
(2011)
Oral Oncol
, vol.47
, pp. 472-481
-
-
Chen, H.1
Zhou, L.2
Wan, G.3
Dou, T.4
Tian, J.5
-
25
-
-
73649102464
-
EZH2 Is Essential for glioblastoma cancer stem cell maintenance
-
Suvà ML, Riggi N, Janiszewska M, Radovanovic I, Provero P, Stehle JC, Baumer K, Le Bitoux MA, Marino D, Cironi L, et al: EZH2 Is Essential for glioblastoma cancer stem cell maintenance. Cancer Res 69: 9211-9218, 2009.
-
(2009)
Cancer Res
, vol.69
, pp. 9211-9218
-
-
Suvà, M.L.1
Riggi, N.2
Janiszewska, M.3
Radovanovic, I.4
Provero, P.5
Stehle, J.C.6
Baumer, K.7
Le Bitoux, M.A.8
Marino, D.9
Cironi, L.10
-
26
-
-
43249127096
-
Polycomb repressive complex 2 (PRC2) restricts hematopoietic stem cell activity
-
Majewski IJ, Blewitt ME, de Graaf CA, McManus EJ, Bahlo M, Hilton AA, Hyland CD, Smyth GK, Corbin JE, Metcalf D, et al: Polycomb repressive complex 2 (PRC2) restricts hematopoietic stem cell activity. PLoS Biol 6: e93, 2008.
-
(2008)
PLoS Biol
, vol.6
-
-
Majewski, I.J.1
Blewitt, M.E.2
de Graaf, C.A.3
McManus, E.J.4
Bahlo, M.5
Hilton, A.A.6
Hyland, C.D.7
Smyth, G.K.8
Corbin, J.E.9
Metcalf, D.10
-
27
-
-
84873436772
-
EZH2 is required for breast and pancreatic cancer stem cell maintenance and can be used as a functional cancer stem cell reporter
-
van Vlerken LE, Kiefer CM, Morehouse C, Li Y, Groves C, Wilson SD, Yao Y, Hollingsworth RE and Hurt EM: EZH2 is required for breast and pancreatic cancer stem cell maintenance and can be used as a functional cancer stem cell reporter. Stem Cells Transl Med 2: 43-52, 2013.
-
(2013)
Stem Cells Transl Med
, vol.2
, pp. 43-52
-
-
van Vlerken, L.E.1
Kiefer, C.M.2
Morehouse, C.3
Li, Y.4
Groves, C.5
Wilson, S.D.6
Yao, Y.7
Hollingsworth, R.E.8
Hurt, E.M.9
-
28
-
-
84870573126
-
EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations
-
McCabe MT, Ott HM, Ganji G, Korenchuk S, Thompson C, Van Aller GS, Liu Y, Graves AP, Della Pietra A III, Diaz E, et al: EZH2 inhibition as a therapeutic strategy for lymphoma with EZH2-activating mutations. Nature 492: 108-112, 2012.
-
(2012)
Nature
, vol.492
, pp. 108-112
-
-
McCabe, M.T.1
Ott, H.M.2
Ganji, G.3
Korenchuk, S.4
Thompson, C.5
Van Aller, G.S.6
Liu, Y.7
Graves, A.P.8
Della Pietra, A.9
Diaz, E.10
-
29
-
-
77349122071
-
The knock-down of overexpressed EZH2 and BMI-1 does not prevent osteosarcoma growth
-
Sasaki H, Setoguchi T, Matsunoshita Y, Gao H, Hirotsu M and Komiya S: The knock-down of overexpressed EZH2 and BMI-1 does not prevent osteosarcoma growth. Oncol Rep 23: 677-684, 2010.
-
(2010)
Oncol Rep
, vol.23
, pp. 677-684
-
-
Sasaki, H.1
Setoguchi, T.2
Matsunoshita, Y.3
Gao, H.4
Hirotsu, M.5
Komiya, S.6
-
30
-
-
80053935847
-
Polycomb protein EZH2 regulates cancer cell fate decision in response to DNA damage
-
Wu Z, Lee ST, Qiao Y, Li Z, Lee PL, Lee YJ, Jiang X, Tan J, Aau M, Lim CZ and Yu Q: Polycomb protein EZH2 regulates cancer cell fate decision in response to DNA damage. Cell Death Differ 18: 1771-1779, 2011.
-
(2011)
Cell Death Differ
, vol.18
, pp. 1771-1779
-
-
Wu, Z.1
Lee, S.T.2
Qiao, Y.3
Li, Z.4
Lee, P.L.5
Lee, Y.J.6
Jiang, X.7
Tan, J.8
Aau, M.9
Lim, C.Z.10
Yu, Q.11
-
31
-
-
84928017601
-
Polycomb protein EZH2 suppresses apoptosis by silencing the proapoptotic miR-31
-
Zhang Q, Padi SK, Tindall DJ and Guo B: Polycomb protein EZH2 suppresses apoptosis by silencing the proapoptotic miR-31. Cell Death Dis 5: e1486, 2014.
-
(2014)
Cell Death Dis
, vol.5
-
-
Zhang, Q.1
Padi, S.K.2
Tindall, D.J.3
Guo, B.4
-
32
-
-
84859450097
-
Cancer stem cells and drug resistance: The potential of nanomedicine
-
Serguei V and Xin W: Cancer stem cells and drug resistance: The potential of nanomedicine. Nanomedicine 7: 597-615, 2012.
-
(2012)
Nanomedicine
, vol.7
, pp. 597-615
-
-
Serguei, V.1
Xin, W.2
-
33
-
-
78049307003
-
Overexpression of EZH2 contributes to acquired cisplatin resistance in ovarian cancer cells in vitro and in vivo
-
Hu S, Yu L, Li Z, Shen Y, Wang J, Cai J, Xiao L and Wang Z: Overexpression of EZH2 contributes to acquired cisplatin resistance in ovarian cancer cells in vitro and in vivo. Cancer Biol Ther 10: 788-795, 2010.
-
(2010)
Cancer Biol Ther
, vol.10
, pp. 788-795
-
-
Hu, S.1
Yu, L.2
Li, Z.3
Shen, Y.4
Wang, J.5
Cai, J.6
Xiao, L.7
Wang, Z.8
-
34
-
-
84910054599
-
The prognostic role of EZH2 expression in rectal cancer patients treated with neoadjuvant chemoradiotherapy
-
Meng X, Huang Z, Wang R, Jiao Y, Li H, Xu X, Feng R, Zhu K, Jiang S, Yan H and Yu J: The prognostic role of EZH2 expression in rectal cancer patients treated with neoadjuvant chemoradiotherapy. Radiat Oncol 9: 188, 2014.
-
(2014)
Radiat Oncol
, vol.9
, pp. 188
-
-
Meng, X.1
Huang, Z.2
Wang, R.3
Jiao, Y.4
Li, H.5
Xu, X.6
Feng, R.7
Zhu, K.8
Jiang, S.9
Yan, H.10
Yu, J.11
-
35
-
-
77955541508
-
Regulation of tumor angiogenesis by EZH2
-
Lu CH, Han HD, Mangala LS, Ali-Fehmi R, Newton CS, Ozbun L, Armaiz-Pena GN, Hu W, Stone RL, Munkarah A, et al: Regulation of tumor angiogenesis by EZH2. Cancer Cell 18: 185-197, 2010.
-
(2010)
Cancer Cell
, vol.18
, pp. 185-197
-
-
Lu, C.H.1
Han, H.D.2
Mangala, L.S.3
Ali-Fehmi, R.4
Newton, C.S.5
Ozbun, L.6
Armaiz-Pena, G.N.7
Hu, W.8
Stone, R.L.9
Munkarah, A.10
-
36
-
-
84877807808
-
Non-coding RNAs and EZH2 interactions in cancer: Long and short tales from the transcriptome
-
Benetatos L, Voulgaris E, Vartholomatos G and Hatzimichael E: Non-coding RNAs and EZH2 interactions in cancer: Long and short tales from the transcriptome. Int J Cancer 133: 267-274, 2013.
-
(2013)
Int J Cancer
, vol.133
, pp. 267-274
-
-
Benetatos, L.1
Voulgaris, E.2
Vartholomatos, G.3
Hatzimichael, E.4
-
37
-
-
84907565517
-
Cisplatin and paclitaxel target significant long noncoding RNAs in laryngeal squamous cell carcinoma
-
Chen H, Xin Y, Zhou L, Huang JM, Tao L, Cheng L and Tian J: Cisplatin and paclitaxel target significant long noncoding RNAs in laryngeal squamous cell carcinoma. Med Oncol 31: 246, 2014.
-
(2014)
Med Oncol
, vol.31
, pp. 246
-
-
Chen, H.1
Xin, Y.2
Zhou, L.3
Huang, J.M.4
Tao, L.5
Cheng, L.6
Tian, J.7
|