Tumor directed, scalp sparing intensity modulated whole brain radiotherapy for brain metastases

Technology in Cancer Research and Treatment

Volumn 14, Issue 5, 2015, Pages 547-555

  Kao, Johnny ^a   Darakchiev, Boramir ^a   Conboy, Linda ^a   Ogurek, Sara ^a   Sharma, Neha ^a   Ren, Xuemin ^a   Pettit, Jeffrey ^a  

^a Good Samaritan Hospital Medical Center   (United States)

Author keywords

Brain metastases; Intensity modulated radiation therapy; Prophylactic cranial irradiation; Scalp sparing IMRT; Whole brain radiotherapy

Indexed keywords

CORTICOSTEROID;

ADULT; AGED; ARTICLE; BRAIN METASTASIS; CLINICAL ARTICLE; COLLIMATOR; CONTROLLED STUDY; DOSIMETRY; ERYTHEMA; FATIGUE; FEMALE; FOLLOW UP; HAIR LOSS; HUMAN; HYPERGLYCEMIA; INSOMNIA; INTENSITY MODULATED RADIATION THERAPY; LINEAR ACCELERATOR; MALE; OVERALL SURVIVAL; PRURITUS; RADIATION DOSE; RELAPSE; RETROSPECTIVE STUDY; THRUSH; TREATMENT PLANNING; WEIGHT GAIN; BRAIN; BRAIN NEOPLASMS; COMPUTER ASSISTED TOMOGRAPHY; CONSERVATIVE TREATMENT; MIDDLE AGED; MORTALITY; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOLOGY; PROCEDURES; RADIATION RESPONSE; RADIOGRAPHY; RADIOTHERAPY DOSAGE; RADIOTHERAPY PLANNING SYSTEM; SECONDARY;

AGED; BRAIN; BRAIN NEOPLASMS; FEMALE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; ORGAN SPARING TREATMENTS; RADIOTHERAPY DOSAGE; RADIOTHERAPY PLANNING, COMPUTER-ASSISTED; RADIOTHERAPY, INTENSITY-MODULATED; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84976568327     PISSN: 15330346     EISSN: 15330338     Source Type: Journal    
DOI: 10.7785/tcrt.2012.500426     Document Type: Article

References (41)

1. Horton, J., Baxter, D. H., Olson, K. B. The management of metastases to the brain by irradiation and corticosteroids. Am J Roentgenol Radium Ther Nucl Med 111, 334-336 (1971).
2. Wen, P. Y., Loeffler, J. S. Management of brain metastases. Oncology (Williston Park) 13, 941-954, 957-961; Discussion 961-942, 949 (1999).
3. Aoyama, H., Shirato, H., Tago, M., Nakagawa, K., Toyoda, T., Hatano, K., Kenjyo, M., Oya, N., Hirota, S., Shioura, H., Kunieda, E., Inomata, T., Hayakawa, K., Katoh, N., Kobashi, G. Stereotactic radiosurgery plus whole-brain radiation therapy vs stereotactic radiosurgery alone for treatment of brain metastases: a randomized controlled trial. JAMA 295, 2483-2491 (2006). DOI: 295/21/2483 [pii] 10.1001/jama.295.21.2483
4. Kocher, M., Soffietti, R., Abacioglu, U., Villa, S., Fauchon, F., Baumert, B. G., Fariselli, L., Tzuk-Shina, T., Kortmann, R. D., Carrie, C., Ben Hassel, M., Kouri, M., Valeinis, E., van den Berge, D., Collette, S., Collette, L., Mueller, R. P. Adjuvant whole-brain radiotherapy versus observation after radiosurgery or surgical resection of one to three cerebral metastases: results of the EORTC 22952-26001 study. J Clin Oncol 29, 134-141 (2011). DOI: JCO.2010.30.1655 [pii] 10.1200/JCO.2010.30.1655
5. Patchell, R. A., Tibbs, P. A., Regine, W. F., Dempsey, R. J., Mohiuddin, M., Kryscio, R. J., Markesbery, W. R., Foon, K. A., Young, B. Postoperative radiotherapy in the treatment of single metastases to the brain: A randomized trial. JAMA 280, 1485-1489 (1998). DOI: joc80445 [pii]
6. Kim, D. G., Lunsford, L. D. Current and Future Management of Brain Metastasis. Karger: Basel, Switzerland (2012).
7. Borgelt, B., Gelber, R., Kramer, S., Brady, L. W., Chang, C. H., Davis, L. W., Perez, C. A., Hendrickson, F. R. The palliation of brain metastases: final results of the first two studies by the Radiation Therapy Oncology Group. Int J Radiat Oncol Biol Phys 6, 1-9 (1980).
8. Knisely, J. P., Berkey, B., Chakravarti, A., Yung, A. W., Curran, W. J, Jr., Robins, H. I., Movsas, B., Brachman, D. G., Henderson, R. H., Mehta, M. P. A phase III study of conventional radiation therapy plus thalidomide versus conventional radiation therapy for multiple brain metastases (RTOG 0118). Int J Radiat Oncol Biol Phys 71, 79-86 (2008). DOI: S0360-3016(07)04231-9 [pii] 10.1016/j.ijrobp.2007.09.016
9. Mehta, M. P., Rodrigus, P., Terhaard, C. H., Rao, A., Suh, J., Roa, W., Souhami, L., Bezjak, A., Leibenhaut, M., Komaki, R., Schultz, C., Timmerman, R., Curran, W., Smith, J., Phan, S. C., Miller, R. A., Renschler, M. F. Survival and neurologic outcomes in a randomized trial of motexafin gadolinium and whole-brain radiation therapy in brain metastases. J Clin Oncol 21, 2529-2536 (2003). DOI: 10.1200/JCO.2003.12.122 JCO.2003.12.122 [pii]
10. Murray, K. J., Scott, C., Greenberg, H. M., Emami, B., Seider, M., Vora, N. L., Olson, C., Whitton, A., Movsas, B., Curran, W. A randomized phase III study of accelerated hyperfractionation versus standard in patients with unresected brain metastases: a report of the Radiation Therapy Oncology Group (RTOG) 9104. Int J Radiat Oncol Biol Phys 39, 571-574 (1997). DOI: S0360-3016(97)00341-6 [pii]
11. Gondi, V., Tome, W. A., Mehta, M. P. Why avoid the hippocampus? A comprehensive review. Radiother Oncol 97, 370-376 (2010). DOI: S0167-8140(10)00539-6 [pii] 10.1016/j.radonc.2010.09.013
12. Andrews, D. W., Scott, C. B., Sperduto, P. W., Flanders, A. E., Gaspar, L. E., Schell, M. C., Werner-Wasik, M., Demas, W., Ryu, J., Bahary, J. P., Souhami, L., Rotman, M., Mehta, M. P., Curran, W. J., Jr. Whole brain radiation therapy with or without stereotactic radiosurgery boost for patients with one to three brain metastases: phase III results of the RTOG 9508 randomised trial. Lancet 363, 1665-1672 (2004). DOI: 10.1016/S0140-6736(04)16250-8 [pii] S0140-6736(04)16250-8
13. Kondziolka, D., Patel, A., Lunsford, L. D., Kassam, A., Flickinger, J. C. Stereotactic radiosurgery plus whole brain radiotherapy versus radiotherapy alone for patients with multiple brain metastases. Int J Radiat Oncol Biol Phys 45, 427-434 (1999). DOI: S0360-3016(99)00198-4 [pii]
14. Chang, E. L., Wefel, J. S., Hess, K. R., Allen, P. K., Lang, F. F., Kornguth, D. G., Arbuckle, R. B., Swint, J. M., Shiu, A. S., Maor, M. H., Meyers, C. A. Neurocognition in patients with brain metastases treated with radiosurgery or radiosurgery plus whole-brain irradiation: a randomised controlled trial. Lancet Oncol 10, 1037-1044 (2009). DOI: S1470-2045(09)70263-3 [pii] 10.1016/S1470-2045(09)70263-3
15. Li, J., Bentzen, S. M., Renschler, M., Mehta, M. P. Regression after whole-brain radiation therapy for brain metastases correlates with survival and improved neurocognitive function. J Clin Oncol 25, 1260-1266 (2007). DOI: 25/10/1260 [pii] 10.1200/JCO.2006.09.2536
16. Suh, J. H. Stereotactic radiosurgery for the management of brain metastases. N Engl J Med 362, 1119-1127 (2010). DOI: 362/12/1119[pii] 10.1056/NEJMct0806951
17. Metz, J. M., Smith, D., Mick, R., Lustig, R., Mitchell, J., Cherakuri, M., Glatstein, E., Hahn, S. M. A phase I study of topical Tempol for the prevention of alopecia induced by whole brain radiotherapy. Clin Cancer Res 10, 6411-6417 (2004). DOI: 10/19/6411[pii]10.1158/1078-0432.CCR-04-0658
18. Wong, J., Hird, A., Kirou-Mauro, A., Napolskikh, J., Chow, E. Quality of life in brain metastases radiation trials: a literature review. Curr Oncol 15, 25-45 (2008).
19. DeAngelis, L. M., Delattre, J. Y., Posner, J. B. Radiation-induced dementia in patients cured of brain metastases. Neurology 39, 789-796 (1989).
20. Kao, J., Genden, E. M., Gupta, V., Policarpio, E. L., Burri, R. J., Rivera, M., Gurudutt, V., Som, P. M., Teng, M., Packer, S. H. Phase 2 trial of concurrent 5-fluorouracil, hydroxyurea, cetuximab, and hyperfractionated intensity-modulated radiation therapy for locally advanced head and neck cancer. Cancer 117, 318-326 (2011). DOI: 10.1002/cncr.25374
21. Pawlicki, T., Mundt, A. J. Quality and Safety in Radiotherapy. CRC Press/Taylor & Francis: Boca Raton, Florida (2011).
22. Gaspar, L., Scott, C., Rotman, M., Asbell, S., Phillips, T., Wasserman, T., McKenna, W. G., Byhardt, R. Recursive partitioning analysis (RPA) of prognostic factors in three Radiation Therapy Oncology Group (RTOG) brain metastases trials. Int J Radiat Oncol Biol Phys 37, 745-751 (1997). DOI: S0360-3016(96)00619-0 [pii]
23. Yamamoto, M., Sato, Y., Serizawa, T., Kawabe, T., Higuchi, Y., Nagano, O., Barfod, B. E., Ono, J., Kasuya, H., Urakawa, Y. Subclassification of recursive partitioning analysis Class II patients with brain metastases treated radiosurgically. Int J Radiat Oncol Biol Phys 83, 1399-1405 (2012). DOI: S0360-3016(11)03380-3 [pii] 10.1016/j.ijrobp.2011.10.018
24. Mundt, A. J., Roeske, J. C. Intensity Modulated Radiation Therapy: A Clinical Perspective. BC Decker: Hamilton, Canada (2005).
25. Gondi, V., Tolakanahalli, R., Mehta, M. P., Tewatia, D., Rowley, H., Kuo, J. S., Khuntia, D., Tome, W. A. Hippocampal-sparing wholebrain radiotherapy: A “how-to” technique using helical tomotherapy and linear accelerator-based intensity-modulated radiotherapy. Int J Radiat Oncol Biol Phys 78, 1244-1252 (2010). DOI: S0360-3016(10)00139-2 [pii] 10.1016/j.ijrobp.2010.01.039
26. Marsh, J. C., Gielda, B. T., Herskovic, A. M., Abrams, R. A. Cognitive sparing during the administration of whole brain radiotherapy and prophylactic cranial irradiation: current concepts and approaches. J Oncol 2010, 198208 (2010). DOI: 10.1155/2010/198208
27. Edwards, A. A., Keggin, E., Plowman, P. N. The developing role for intensity-modulated radiation therapy (IMRT) in the non-surgical treatment of brain metastases. Br J Radiol 83, 133-136 (2010). DOI: 28596848 [pii]10.1259/bjr/28596848
28. Roberge, D., Parker, W., Niazi, T. M., Olivares, M. Treating the contents and not the container: dosimetric study of hair-sparing whole brain intensity modulated radiation therapy. Technol Cancer Res Treat 4, 567-570 (2005). DOI: d53022&c54187&p513129&do5detail [pii]
29. Lawenda, B. D., Gagne, H. M., Gierga, D. P., Niemierko, A., Wong, W. M., Tarbell, N. J., Chen, G. T., Hochberg, F. H., Loeffler, J. S. Permanent alopecia after cranial irradiation: dose-response relationship. Int J Radiat Oncol Biol Phys 60, 879-887 (2004). DOI: S0360301604006698 [pii] 10.1016/j.ijrobp.2004.04.031
30. Severs, G. A., Griffin, T., Werner-Wasik, M. Cicatricial alopecia secondary to radiation therapy: Case report and review of the literature. Cutis 81, 147-153 (2008).
31. Gani, C., Muller, A. C., Eckert, F., Schroeder, C., Bender, B., Pantazis, G., Bamberg, M., Berger, B. Outcome after whole brain radiotherapy alone in intracranial leptomeningeal carcinomatosis from solid tumors. Strahlenther Onkol 188, 148-153 (2012). DOI: 10.1007/s00066-011-0025-8
32. Olsen, E. A. Investigative guidelines for alopecia areata. Dermatol Ther 24, 311-319 (2011). DOI: 10.1111/j.1529-8019.2011.01415.x
33. Graham, P. H., Bucci, J., Browne, L. Randomized comparison of whole brain radiotherapy, 20 Gy in four daily fractions versus 40 Gy in 20 twice-daily fractions, for brain metastases. Int J Radiat Oncol Biol Phys 77, 648-654 (2010). DOI: S0360-3016(09)00795-0 [pii] 10.1016/j.ijrobp.2009.05.032
34. Gore, E. M., Bae, K., Wong, S. J., Sun, A., Bonner, J. A., Schild, S. E., Gaspar, L. E., Bogart, J. A., Werner-Wasik, M., Choy, H. Phase III comparison of prophylactic cranial irradiation versus observation in patients with locally advanced non-small-cell lung cancer: primary analysis of radiation therapy oncology group study RTOG 0214. J Clin Oncol 29, 272-278 (2011). DOI: JCO.2010.29.1609 [pii] 10.1200/JCO.2010.29.1609
35. Le Pechoux, C., Dunant, A., Senan, S., Wolfson, A., Quoix, E., Faivre-Finn, C., Ciuleanu, T., Arriagada, R., Jones, R., Wanders, R., Lerouge, D., Laplanche, A. Standard-dose versus higher-dose prophylactic cranial irradiation (PCI) in patients with limited-stage small-cell lung cancer in complete remission after chemotherapy and thoracic radiotherapy (PCI 99-01, EORTC 22003-08004, RTOG 0212, and IFCT 99-01): a randomised clinical trial. Lancet Oncol 10, 467-474 (2009). DOI: S1470-2045(09)70101-9 [pii] 10.1016/S1470-2045(09)70101-9
36. Slotman, B., Faivre-Finn, C., Kramer, G., Rankin, E., Snee, M., Hatton, M., Postmus, P., Collette, L., Musat, E., Senan, S. Prophylactic cranial irradiation in extensive small-cell lung cancer. N Engl J Med 357, 664-672 (2007). DOI: 357/7/664 [pii] 10.1056/NEJMoa071780
37. Sun, A., Bae, K., Gore, E. M., Movsas, B., Wong, S. J., Meyers, C. A., Bonner, J. A., Schild, S. E., Gaspar, L. E., Bogart, J. A., Werner-Wasik, M., Choy, H. Phase III trial of prophylactic cranial irradiation compared with observation in patients with locally advanced non-small-cell lung cancer: neurocognitive and quality-of-life analysis. J Clin Oncol 29, 279-286 (2011). DOI: JCO.2010.29.6053 [pii] 10.1200/JCO.2010.29.6053
38. Welzel, G., Fleckenstein, K., Schaefer, J., Hermann, B., Kraus-Tiefenbacher, U., Mai, S. K., Wenz, F. Memory function before and after whole brain radiotherapy in patients with and without brain metastases. Int J Radiat Oncol Biol Phys 72, 1311-1318 (2008). DOI: S0360-3016(08)00488-4 [pii] 10.1016/j.ijrobp.2008.03.009
39. Auperin, A., Arriagada, R., Pignon, J. P., Le Pechoux, C., Gregor, A., Stephens, R. J., Kristjansen, P. E., Johnson, B. E., Ueoka, H., Wagner, H., Aisner, J. Prophylactic cranial irradiation for patients with small-cell lung cancer in complete remission. Prophylactic Cranial Irradiation Overview Collaborative Group. N Engl J Med 341, 476-484 (1999). DOI: 10.1056/NEJM199908123410703
40. Khan, A. J., Dicker, A. P. On the merits and limitations of wholebrain radiation therapy. J Clin Oncol 31, 11-13 (2013). DOI: JCO.2012.46.0410 [pii] 10.1200/JCO.2012.46.0410
41. Bhatnagar, A. K., Flickinger, J. C., Kondziolka, D., Lunsford, L. D. Stereotactic radiosurgery for four or more intracranial metastases. Int J Radiat Oncol Biol Phys 64, 898-903 (2006). DOI: S0360-3016(05)02580-0 [pii] 10.1016/j.ijrobp.2005.08.035