Unique geometry of sister kinetochores in human oocytes during meiosis I may explain maternal age-associated increases in chromosomal abnormalities

Biology Open

Volumn 5, Issue 2, 2016, Pages 178-184

  Patel, Jessica ^a   Tan, Seang Lin ^b   Hartshorne, Geraldine M ^a,c   McAinsh, Andrew D ^a  

^a UNIVERSITY OF WARWICK   (United Kingdom)

^b MCGILL UNIVERSITY   (Canada)

^c UNIVERSITY HOSPITALS COVENTRY AND WARWICKSHIRE NHS TRUST   (United Kingdom)

Author keywords

Aneuploidy; Chromosome segregation; Human; Kinetochore; Meiosis; Oocyte

Indexed keywords

COHESIN;

ADULT; ANEUPLOIDY; ARTICLE; CELL ADHESION; CENTROMERE; CHROMOSOME ABERRATION; CONTROLLED STUDY; FEMALE; GEOMETRY; HUMAN; HUMAN CELL; KINETOCHORE MICROTUBULE; MATERNAL AGE; MEIOSIS; MEIOTIC SPINDLE; MOLECULAR PATHOLOGY; OOCYTE; SIGNAL TRANSDUCTION; SISTER KINETOCHORE;

EID: 84976490154     PISSN: None     EISSN: 20466390     Source Type: Journal    
DOI: 10.1242/bio.016394     Document Type: Article

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