Reduced frontal-subcortical white matter connectivity in association with suicidal ideation in major depressive disorder

Translational Psychiatry

Volumn 6, Issue 6, 2016, Pages

  Myung, W ^a   Han, C E ^b   Fava, M ^c   Mischoulon, D ^c   Papakostas, G I ^c   Heo, J Y ^a   Kim, K W ^a   Kim, S T ^a   Kim, D J H ^a   Kim, D K ^a   Seo, S W ^a   Seong, J K ^b   Jeon, H J ^a,c,d  

^a Sungkyunkwan University School of Medicine   (South Korea)

^b Korea University   (South Korea)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d Sungkyunkwan University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BARRATT IMPULSIVENESS SCALE; BEHAVIOR DISORDER ASSESSMENT; BRAIN FUNCTION; BRAIN MAPPING; CAUDATE NUCLEUS; CLINICAL ARTICLE; CONNECTOME; CONTROLLED STUDY; CORRELATIONAL STUDY; DIFFUSION TENSOR IMAGING; DISEASE ASSOCIATION; DISEASE SEVERITY ASSESSMENT; EXECUTIVE FUNCTION; FEMALE; FRONTAL CORTEX; GLOBUS PALLIDUS; GRAPH THEORETICAL ANALYSIS; HUMAN; IMAGING SOFTWARE; IMPULSIVENESS; LEFT HEMISPHERE; MAJOR DEPRESSION; MALE; MATHEMATICAL ANALYSIS; MENTAL PATIENT; NETWORK BASED STATISTICS; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; PUTAMEN; ROSTRAL MIDDLE FRONTAL CORTEX; SCALE FOR SUICIDE IDEATION; STATISTICAL ANALYSIS; SUBCORTEX; SUICIDAL IDEATION; SUPERIOR PARIETAL CORTEX; THALAMUS; WHITE MATTER; BRAIN; COMPUTER ASSISTED DIAGNOSIS; DIAGNOSTIC IMAGING; DIFFUSION WEIGHTED IMAGING; HEMISPHERIC DOMINANCE; MIDDLE AGED; NERVE CELL NETWORK; PATHOPHYSIOLOGY; PHYSIOLOGY; PSYCHOLOGY; QUESTIONNAIRE; REFERENCE VALUE;

BRAIN; BRAIN MAPPING; DEPRESSIVE DISORDER, MAJOR; DIFFUSION MAGNETIC RESONANCE IMAGING; DOMINANCE, CEREBRAL; EXECUTIVE FUNCTION; FEMALE; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; IMPULSIVE BEHAVIOR; MALE; MIDDLE AGED; NERVE NET; REFERENCE VALUES; SUICIDAL IDEATION; SURVEYS AND QUESTIONNAIRES; WHITE MATTER;

EID: 84976448459     PISSN: None     EISSN: 21583188     Source Type: Journal    
DOI: 10.1038/tp.2016.110     Document Type: Article

References (82)

1. Lozano R, Naghavi M, Foreman K, Lim S, Shibuya K, Aboyans V et al. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: A systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012; 380: 2095-2128.
2. Bradvik L, Mattisson C, Bogren M, Nettelbladt P. Long-Term suicide risk of depression in the Lundby cohort 1947-1997-severity and gender. Acta Psychiatr Scand 2008; 117: 185-191.
3. Angst F, Stassen HH, Clayton PJ, Angst J. Mortality of patients with mood disorders: follow-up over 34-38 years. J Affect Disord 2002; 68: 167-181.
4. Jeon HJ, Lee JY, Lee YM, Hong JP, Won SH, Cho SJ et al. Unplanned versus planned suicide attempters, precipitants, methods, and an association with mental disorders in a Korea-based community sample. J Affect Disord 2010; 127: 274-280.
5. Baek JH, Kang ES, Fava M, Mischoulon D, Nierenberg AA, Yu BH et al. Serum lipids, recent suicide attempt and recent suicide status in patients with major depressive disorder. Prog Neuropsychopharmacol Biol Psychiatry 2014; 51: 113-118.
6. Isung J, Aeinehband S, Mobarrez F, Nordstrom P, Runeson B, Asberg M et al. High interleukin-6 and impulsivity: determining the role of endophenotypes in attempted suicide. Transl Psychiatry 2014; 4: e470.
7. Jeon HJ, Hong JP, Fava M, Mischoulon D, Nyer M, Inamori A et al. Childhood parental death and lifetime suicide attempt of the opposite-gender offspring in a nationwide community sample of Korea. Suicide Life Threat Behav 2013; 43: 598-610.
8. Jeon HJ, Roh MS, Kim KH, Lee JR, Lee D, Yoon SC et al. Early trauma and lifetime suicidal behavior in a nationwide sample of Korean medical students. J Affect Disord 2009; 119: 210-214.
9. Kaminsky Z, Wilcox HC, Eaton WW, Van Eck K, Kilaru V, Jovanovic T et al. Epigenetic and genetic variation at SKA2 predict suicidal behavior and post-Traumatic stress disorder. Transl Psychiatry 2015; 5: e627.
10. Anestis MD, Soberay KA, Gutierrez PM, Hernandez TD, Joiner TE. Reconsidering the link between impulsivity and suicidal behavior. Pers Soc Psychol Rev 2014; 18: 366-386.
11. Pfaff JJ, Almeida OP. Identifying suicidal ideation among older adults in a general practice setting. J Affect Disord 2004; 83: 73-77.
12. Szanto K, Mulsant BH, Houck P, Dew MA, Reynolds CF 3rd. Occurrence and course of suicidality during short-Term treatment of late-life depression. Arch Gen Psychiatry 2003; 60: 610-617.
13. Laje G, Paddock S, Manji H, Rush AJ, Wilson AF, Charney D et al. Genetic markers of suicidal ideation emerging during citalopram treatment of major depression. Am J Psychiatry 2007; 164: 1530-1538.
14. Kang HJ, Kim JM, Lee JY, Kim SY, Bae KY, Kim SW et al. BDNF promoter methylation and suicidal behavior in depressive patients. J Affect Disord 2013; 151: 679-685.
15. Grangeon MC, Seixas C, Quarantini LC, Miranda-Scippa A, Pompili M, Steffens DC et al. White matter hyperintensities and their association with suicidality in major affective disorders: A meta-Analysis of magnetic resonance imaging studies. CNS Spectr 2010; 15: 375-381.
16. Ding Y, Lawrence N, Olie E, Cyprien F, le Bars E, Bonafe A et al. Prefrontal cortex markers of suicidal vulnerability in mood disorders: A model-based structural neuroimaging study with a translational perspective. Transl Psychiatry 2015; 5: e516.
17. Jollant F, Lawrence NS, Giampietro V, Brammer MJ, Fullana MA, Drapier D et al. Orbitofrontal cortex response to angry faces in men with histories of suicide attempts. Am J Psychiatry 2008; 165: 740-748.
18. Audenaert K, Goethals I, Van Laere K, Lahorte P, Brans B, Versijpt J et al. SPECT neuropsychological activation procedure with the Verbal Fluency Test in attempted suicide patients. Nucl Med Commun 2002; 23: 907-916.
19. Willeumier K, Taylor DV, Amen DG. Decreased cerebral blood flow in the limbic and prefrontal cortex using SPECT imaging in a cohort of completed suicides. Transl Psychiatry 2011; 1: e28.
20. Audenaert K, Van Laere K, Dumont F, Slegers G, Mertens J, van Heeringen C et al. Decreased frontal serotonin 5-HT 2a receptor binding index in deliberate selfharm patients. Eur J Nucl Med 2001; 28: 175-182.
21. Jia Z, Wang Y, Huang X, Kuang W, Wu Q, Lui S et al. Impaired frontothalamic circuitry in suicidal patients with depression revealed by diffusion tensor imaging at 3.0 T. J Psychiatry Neurosci 2014; 39: 170-177.
22. Jia Z, Huang X, Wu Q, Zhang T, Lui S, Zhang J et al. High-field magnetic resonance imaging of suicidality in patients with major depressive disorder. Am J Psychiatry 2010; 167: 1381-1390.
23. Cox Lippard ET, Johnston JA, Blumberg HP. Neurobiological risk factors for suicide: insights from brain imaging. Am J Prev Med 2014; 47: S152-S162.
24. Zhang H, Chen Z, Jia Z, Gong Q. Dysfunction of neural circuitry in depressive patients with suicidal behaviors: A review of structural and functional neuroimaging studies. Prog Neuropsychopharmacol Biol Psychiatry 2014; 53: 61-66.
25. Klonsky ED, May AM. Differentiating suicide attempters from suicide ideators: A critical frontier for suicidology research. Suicide Life Threat Behav 2014; 44: 1-5.
26. Fried EI, Nesse RM. Depression sum-scores don't add up: why analyzing specific depression symptoms is essential. BMC Med 2015; 13: 72.
27. Fornito A, Zalesky A, Breakspear M. Graph analysis of the human connectome: promise, progress, and pitfalls. Neuroimage 2013; 80: 426-444.
28. Sporns O. Networks of the Brain. MIT Press:Cambridge, MA, USA, 2011.
29. Bullmore E, Sporns O. Complex brain networks: graph theoretical analysis of structural and functional systems. Nat Rev Neurosci 2009; 10: 186-198.
30. Zalesky A, Fornito A, Bullmore ET. Network-based statistic: identifying differences in brain networks. Neuroimage 2010; 53: 1197-1207.
31. Zhang J, Wang J, Wu Q, Kuang W, Huang X, He Y et al. Disrupted brain connectivity networks in drug-naive, first-episode major depressive disorder. Biol Psychiatry 2011; 70: 334-342.
32. Zalesky A, Fornito A, Seal ML, Cocchi L, Westin CF, Bullmore ET et al. Disrupted axonal fiber connectivity in schizophrenia. Biol Psychiatry 2011; 69: 80-89.
33. Korgaonkar MS, Fornito A, Williams LM, Grieve SM. Abnormal structural networks characterize major depressive disorder: A connectome analysis. Biol Psychiatry 2014; 76: 567-574.
34. American Psychiatric Association, American Psychiatric Association Task Force on DSM-IV. Diagnostic and Statistical Manual of Mental Disorders: DSM-IV-TR, 4th text ver edn. American Psychiatric Association: Washington, DC, USA, 2000.
35. Hamilton M. Development of a rating scale for primary depressive illness. Br J Soc Clin Psychol 1967; 6: 278-296.
36. van Vliet IM, de Beurs E. [The MINI-International Neuropsychiatric Interview. A brief structured diagnostic psychiatric interview for DSM-IV en ICD-10 psychiatric disorders]. Tijdschr Psychiatr 2007; 49: 393-397.
37. Beck AT, Kovacs M, Weissman A. Assessment of suicidal intention: The scale for suicide ideation. J Consult Clin Psychol 1979; 47: 343-352.
38. Barratt ES Impulsiveness and aggression. In: Monahan J, Steadman HJ (eds). Violence and Mental Disorder: Developments in Risk Assessment. University of Chicago Press: Chicago, 1994, pp 61-79.
39. Hirschfeld RM, Williams JB, Spitzer RL, Calabrese JR, Flynn L, Keck PE Jr. et al. Development and validation of a screening instrument for bipolar spectrum disorder: The Mood Disorder Questionnaire. Am J Psychiatry 2000; 157: 1873-1875.
40. Angst J, Adolfsson R, Benazzi F, Gamma A, Hantouche E, Meyer TD et al. The HCL-32: Towards a self-Assessment tool for hypomanic symptoms in outpatients. J Affect Disord 2005; 88: 217-233.
41. Fischl B, van der Kouwe A, Destrieux C, Halgren E, Segonne F, Salat DH et al. Automatically parcellating the human cerebral cortex. Cereb Cortex 2004; 14: 11-22.
42. Desikan RS, Segonne F, Fischl B, Quinn BT, Dickerson BC, Blacker D et al. An automated labeling system for subdividing the human cerebral cortex on MRI scans into gyral based regions of interest. Neuroimage 2006; 31: 968-980.
43. Mori S, Barker PB. Diffusion magnetic resonance imaging: its principle and applications. Anat Rec 1999; 257: 102-109.
44. Wang R, Benner T, Sorensen AG, Wedeen VJ. Diffusion Toolkit: A software package for diffusion imaging data processing and tractography. Proc Intl Soc Mag Reson Med 2007; 15: 3720.
45. Rubinov M, Sporns O. Complex network measures of brain connectivity: uses and interpretations. NeuroImage 2010; 52: 1059-1069.
46. Watts DJ, Strogatz SH. Collective dynamics of 'small-world' networks. Nature 1998; 393: 440-442.
47. Guimera R, Nunes Amaral LA. Functional cartography of complex metabolic networks. Nature 2005; 433: 895-900.
48. Achard S, Bullmore E. Efficiency and cost of economical brain functional networks. PLoS Comput Biol 2007; 3: e17.
49. Latora V, Marchiori M. Efficient behavior of small-world networks. Phys Rev Lett 2001; 87: 198701.
50. Bullmore ET, Suckling J, Overmeyer S, Rabe-Hesketh S, Taylor E, Brammer MJ. Global, voxel, and cluster tests, by theory and permutation, for a difference between two groups of structural MR images of the brain. IEEE Trans Med Imaging 1999; 18: 32-42.
51. Benjamini Y, Hochberg Y. Controlling the false discovery rate: A practical and powerful approach to multiple testing. J R Statist Soc B 1995; 57: 289-300.
52. Koechlin E, Hyafil A. Anterior prefrontal function and the limits of human decision-making. Science 2007; 318: 594-598.
53. Ramnani N, Owen AM. Anterior prefrontal cortex: insights into function from anatomy and neuroimaging. Nat Rev Neurosci 2004; 5: 184-194.
54. Newman SD, Carpenter PA, Varma S, Just MA. Frontal and parietal participation in problem solving in the Tower of London: fMRI and computational modeling of planning and high-level perception. Neuropsychologia 2003; 41: 1668-1682.
55. Collette F, Van der Linden M, Laureys S, Delfiore G, Degueldre C, Luxen A et al. Exploring the unity and diversity of the neural substrates of executive functioning. Hum Brain Mapp 2005; 25: 409-423.
56. Giakoumatos CI, Tandon N, Shah J, Mathew IT, Brady RO, Clementz BA et al. Are structural brain abnormalities associated with suicidal behavior in patients with psychotic disorders? J Psychiatr Res 2013; 47: 1389-1395.
57. Chen Z, Zhang H, Jia Z, Zhong J, Huang X, Du M et al. Magnetization transfer imaging of suicidal patients with major depressive disorder. Sci Rep 2015; 5: 9670.
58. Westheide J, Quednow BB, Kuhn KU, Hoppe C, Cooper-Mahkorn D, Hawellek B et al. Executive performance of depressed suicide attempters: The role of suicidal ideation. Eur Arch Psychiatry Clin Neurosci 2008; 258: 414-421.
59. Keilp JG, Sackeim HA, Brodsky BS, Oquendo MA, Malone KM, Mann JJ. Neuropsychological dysfunction in depressed suicide attempters. Am J Psychiatry 2001; 158: 735-741.
60. Ridderinkhof KR, van den Wildenberg WP, Segalowitz SJ, Carter CS. Neurocognitive mechanisms of cognitive control: The role of prefrontal cortex in action selection, response inhibition, performance monitoring, and reward-based learning. Brain Cogn 2004; 56: 129-140.
61. McGirr A, Diaconu G, Berlim MT, Pruessner JC, Sable R, Cabot S et al. Dysregulation of the sympathetic nervous system, hypothalamic-pituitary-Adrenal axis and executive function in individuals at risk for suicide. J Psychiatry Neurosci 2010; 35: 399-408.
62. Spinella M. Neurobehavioral correlates of impulsivity: evidence of prefrontal involvement. Int J Neurosci 2004; 114: 95-104.
63. Raine A, Meloy JR, Bihrle S, Stoddard J, LaCasse L, Buchsbaum MS. Reduced prefrontal and increased subcortical brain functioning assessed using positron emission tomography in predatory and affective murderers. Behav Sci Law 1998; 16: 319-332.
64. Heller W, Nitschke JB, Miller GA. Lateralization in emotion and emotional disorders. Curr Direct Psychol Sci 1998; 7: 26-32.
65. Coan JA, Allen JJ, McKnight PE. A capability model of individual differences in frontal EEG asymmetry. Biol Psychol 2006; 72: 198-207.
66. Neal LB, Gable PA. Neurophysiological markers of multiple facets of impulsivity. Biol Psychol 2016; 115: 64-68.
67. Jansen A, Menke R, Sommer J, Förster A, Bruchmann S, Hempleman J et al. The assessment of hemispheric lateralization in functional MRI-robustness and reproducibility. Neuroimage 2006; 33: 204-217.
68. Guye M, Bettus G, Bartolomei F, Cozzone PJ. Graph theoretical analysis of structural and functional connectivity MRI in normal and pathological brain networks. MAGMA 2010; 23: 409-421.
69. Newman ME. Modularity and community structure in networks. Proc Natl Acad Sci USA 2006; 103: 8577-8582.
70. Guimera R, Amaral LA. Cartography of complex networks: modules and universal roles. J Stat Mech 2005; 2005: nihpa35573.
71. Powers RL, Russo M, Mahon K, Brand J, Braga RJ, Malhotra AK et al. Impulsivity in bipolar disorder: relationships with neurocognitive dysfunction and substance use history. Bipolar Disord 2013; 15: 876-884.
72. Matsuo K, Nielsen N, Nicoletti MA, Hatch JP, Monkul ES, Watanabe Y et al. Anterior genu corpus callosum and impulsivity in suicidal patients with bipolar disorder. Neurosci Lett 2010; 469: 75-80.
73. Meng C, Brandl F, Tahmasian M, Shao J, Manoliu A, Scherr M et al. Aberrant topology of striatum's connectivity is associated with the number of episodes in depression. Brain 2014; 137: 598-609.
74. Yurgelun-Todd DA, Bueler CE, McGlade EC, Churchwell JC, Brenner LA, Lopez-Larson MP. Neuroimaging correlates of traumatic brain injury and suicidal behavior. J Head Trauma Rehabil 2011; 26: 276-289.
75. Marchand WR, Lee JN, Garn C, Thatcher J, Gale P, Kreitschitz S et al. Striatal and cortical midline activation and connectivity associated with suicidal ideation and depression in bipolar II disorder. J Affect Disord 2011; 133: 638-645.
76. Matthews S, Spadoni A, Knox K, Strigo I, Simmons A. Combat-exposed war veterans at risk for suicide show hyperactivation of prefrontal cortex and anterior cingulate during error processing. Psychosom Med 2012; 74: 471-475.
77. Berman RM, Cappiello A, Anand A, Oren DA, Heninger GR, Charney DS et al. Antidepressant effects of ketamine in depressed patients. Biol Psychiatry 2000; 47: 351-354.
78. DiazGranados N, Ibrahim LA, Brutsche NE, Ameli R, Henter ID, Luckenbaugh DA et al. Rapid resolution of suicidal ideation after a single infusion of an N-methyl-Daspartate antagonist in patients with treatment-resistant major depressive disorder. J Clin Psychiatry 2010; 71: 1605-1611.
79. Rajkumar R, Fam J, Yeo EY, Dawe GS. Ketamine and suicidal ideation in depression: jumping the gun? Pharmacol Res 2015; 99: 23-35.
80. Elton A, Tripathi SP, Mletzko T, Young J, Cisler JM, James GA et al. Childhood maltreatment is associated with a sex-dependent functional reorganization of a brain inhibitory control network. Hum Brain Mapp 2014; 35: 1654-1667.
81. Behrens T, Berg HJ, Jbabdi S, Rushworth M, Woolrich M. Probabilistic diffusion tractography with multiple fibre orientations: what can we gain? Neuroimage 2007; 34: 144-155.
82. Aganj I, Lenglet C, Jahanshad N, Yacoub E, Harel N, Thompson PM et al. A Hough transform global probabilistic approach to multiple-subject diffusion MRI tractography. Med Image Anal 2011; 15: 414-425.