HDAC inhibition promotes both initial consolidation and reconsolidation of spatial memory in mice

Scientific Reports

Volumn 6, Issue , 2016, Pages

  Villain, Hélène ^a   Florian, Cédrick ^a   Roullet, Pascal ^a  

^a UNIVERSITÉ DE TOULOUSE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BUTYRIC ACID; HISTONE; HISTONE DEACETYLASE INHIBITOR;

ACETYLATION; ANIMAL; DRUG EFFECTS; GENETIC EPIGENESIS; HIPPOCAMPUS; MALE; MAZE TEST; MEMORY CONSOLIDATION; METABOLISM; MOUSE; PROTEIN PROCESSING; SPATIAL MEMORY;

ACETYLATION; ANIMALS; BUTYRIC ACID; EPIGENESIS, GENETIC; HIPPOCAMPUS; HISTONE DEACETYLASE INHIBITORS; HISTONES; MALE; MAZE LEARNING; MEMORY CONSOLIDATION; MICE; PROTEIN PROCESSING, POST-TRANSLATIONAL; SPATIAL MEMORY;

EID: 84976428114     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep27015     Document Type: Article

References (37)

1. McGaugh, J. L. Memory-A century of consolidation. Science 287, 248-51 (2000).
2. Lee, J. L. C. Memory reconsolidation mediates the strengthening of memories by additional learning. Nat. Neurosci. 11, 1264-6 (2008).
3. De Jaeger, X. et al. Characterization of spatial memory reconsolidation. Learn. Mem. 21, 316-24 (2014).
4. Exton-McGuinness, M. T. J., Lee, J. L. C. & Reichelt, A. C. Updating memories-The role of prediction errors in memory reconsolidation. Behav. Brain Res. 278, 375-84 (2015).
5. Przybyslawski, J. & Sara, S. J. Reconsolidation of memory after its reactivation. Behav. Brain Res. 84, 241-246 (1997).
6. Sara, S. J. Retrieval and reconsolidation: Toward a neurobiology of remembering. Learn. Mem. 7, 73-84 (2000).
7. Alberini, C. M. Mechanisms of memory stabilization: Are consolidation and reconsolidation similar or distinct processes? Trends Neurosci. 28, 51-56 (2005).
8. Lee, J. L. C., Everitt, B. J. & Thomas, K. L. Independent cellular processes for hippocampal memory consolidation and reconsolidation. Science 304, 839-43 (2004).
9. Davis, H. P. & Squire, L. R. Protein synthesis and memory: A review. Psychol. Bull. 96, 518-559 (1984).
10. Peixoto, L. & Abel, T. The role of histone acetylation in memory formation and cognitive impairments. Neuropsychopharmacology 38, 62-76 (2013).
11. Bousiges, O. et al. Spatial memory consolidation is associated with induction of several lysine-Acetyltransferase (histone acetyltransferase) expression levels and H2B/H4 acetylation-dependent transcriptional events in the rat hippocampus. Neuropsychopharmacology 35, 2521-37 (2010).
12. Vecsey, C. G. et al. Histone deacetylase inhibitors enhance memory and synaptic plasticity via CREB:CBP-dependent transcriptional activation. J. Neurosci. 27, 6128-40 (2007).
13. McQuown, S. C. et al. HDAC3 is a critical negative regulator of long-Term memory formation. J. Neurosci. 31, 764-74 (2011).
14. Levenson, J. M. et al. Regulation of histone acetylation during memory formation in the hippocampus. J. Biol. Chem. 279, 40545-59 (2004).
15. Guan, J.-S. et al. HDAC2 negatively regulates memory formation and synaptic plasticity. Nature 459, 55-60 (2009).
16. Hawk, J. D., Florian, C. & Abel, T. Post-Training intrahippocampal inhibition of class I histone deacetylases enhances long-Term object-location memory. Learn. Mem. 18, 367-70 (2011).
17. Stefanko, D. P., Barrett, R. M., Ly, A. R., Reolon, G. K. & Wood, M. A. Modulation of long-Term memory for object recognition via HDAC inhibition. Proc. Natl. Acad. Sci. USA 106, 9447-52 (2009).
18. Federman, N., Fustiñana, M. S. & Romano, A. Reconsolidation involves histone acetylation depending on the strength of the memory. Neuroscience 219, 145-56 (2012).
19. Gräff, J. et al. Epigenetic priming of memory updating during reconsolidation to attenuate remote fear memories. Cell 156, 261-76 (2014).
20. Maddox, S. A. & Schafe, G. E. Epigenetic alterations in the lateral amygdala are required for reconsolidation of a Pavlovian fear memory. Learn. Mem. 18, 579-93 (2011).
21. Maddox, S. A., Watts, C. S., Doyère, V. & Schafe, G. E. A naturally-occurring histone acetyltransferase inhibitor derived from Garcinia indica impairs newly acquired and reactivated fear memories. PLoS One 8, e54463 (2013).
22. Maddox, S. A., Watts, C. S. & Schafe, G. E. p300/CBP histone acetyltransferase activity is required for newly acquired and reactivated fear memories in the lateral amygdala. Learn. Mem. 20, 109-19 (2013).
23. Lubin, F. D. & Sweatt, J. D. The IkappaB kinase regulates chromatin structure during reconsolidation of conditioned fear memories. Neuron 55, 942-57 (2007).
24. Si, J. et al. Activation of NF-κ B in basolateral amygdala is required for memory reconsolidation in auditory fear conditioning. PLoS One 7, e43973 (2012).
25. Bredy, T. W. & Barad, M. The histone deacetylase inhibitor valproic acid enhances acquisition, extinction, and reconsolidation of conditioned fear. Learn. Mem. 15, 39-45 (2008).
26. White, A. O. & Wood, M. A. Does stress remove the HDAC brakes for the formation and persistence of long-Term memory? Neurobiol. Learn. Mem., doi: 10.1016/j.nlm.2013.10.007 (2013).
27. Florian, C. & Roullet, P. Hippocampal CA3-region is crucial for acquisition and memory consolidation in Morris water maze task in mice. Behav. Brain Res. 154, 365-374 (2004).
28. Sandi, C., Loscertales, M. & Guaza, C. Experience-dependent facilitating effect of corticosterone on spatial memory formation in the water maze. Eur. J. Neurosci. 9, 637-42 (1997).
29. Intlekofer, K. A. et al. Exercise and sodium butyrate transform a subthreshold learning event into long-Term memory via a brainderived neurotrophic factor-dependent mechanism. Neuropsychopharmacology 38, 2027-34 (2013).
30. Fontán-Lozano, A. et al. Histone deacetylase inhibitors improve learning consolidation in young and in KA-inducedneurodegeneration and SAMP-8-mutant mice. Mol. Cell. Neurosci. 39, 193-201 (2008).
31. Dagnas, M., Micheau, J., Decorte, L., Beracochea, D. & Mons, N. Post-Training, intrahippocampal HDAC inhibition differentially impacts neural circuits underlying spatial memory in adult and aged mice. Hippocampus 25, 827-837 (2015).
32. Fass, D. M., Butler, J. E. F. & Goodman, R. H. Deacetylase activity is required for cAMP activation of a subset of CREB target genes. J. Biol. Chem. 278, 43014-9 (2003).
33. Ricobaraza, A. et al. Phenylbutyrate ameliorates cognitive deficit and reduces tau pathology in an Alzheimers disease mouse model. Neuropsychopharmacology 34, 1721-32 (2009).
34. Lopez-Atalaya, J. P. & Barco, A. Can changes in histone acetylation contribute to memory formation? Trends Genet. 30, 529-39 (2014).
35. Lopez-Atalaya, J. P., Ito, S., Valor, L. M., Benito, E. & Barco, A. Genomic targets, and histone acetylation and gene expression profiling of neural HDAC inhibition. Nucleic Acids Res. 41, 8072-8084 (2013).
36. Benito, E. et al. HDAC inhibitor-dependent transcriptome and memory reinstatement in cognitive decline models. J. Clin. Invest. 125, 3572-3584 (2015).
37. McQuown, S. C. & Wood, M. A. HDAC3 and the molecular brake pad hypothesis. Neurobiol. Learn. Mem. 96, 27-34 (2011).