Correlation between the level of microRNA expression in peripheral blood mononuclear cells and symptomatology in patients with generalized anxiety disorder

Comprehensive Psychiatry

Volumn 69, Issue , 2016, Pages 216-224

  Chen, Sheng Dong ^a,b   Sun, Xin Yang ^c   Niu, Wei ^b   Kong, Ling Ming ^b   He, Ming Jun ^b   Fan, Hui Min ^d   Li, Wan Shuai ^e   Zhong, Ai Fang ^b   Zhang, Li Yi ^b   Lu, Jim ^e,f  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

^b Department of Laboratory No102 Hospital of Chinese People's Liberation Army   (China)

^c Department of Psychiatry and Psychology   (China)

^d CHENGDU MILITARY GENERAL HOSPITAL   (China)

^e GoPath Diagnostic Laboratory Co Ltd   (China)

^f GoPath Laboratories LLC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; MICRORNA 1301; MICRORNA 432 5P; MICRORNA 4484; MICRORNA 4505; MICRORNA 4674; MICRORNA 501 3P; MICRORNA 663; UNCLASSIFIED DRUG;

ADULT; AGE; AGED; ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE ASSOCIATION; DISEASE SEVERITY; ETHNICITY; FEMALE; GENERALIZED ANXIETY DISORDER; HAMILTON ANXIETY SCALE; HUMAN; MAJOR CLINICAL STUDY; MALE; MICROARRAY ANALYSIS; PERIPHERAL BLOOD MONONUCLEAR CELL; REGRESSION ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; SEX DIFFERENCE; SYMPTOMATOLOGY; ANXIETY DISORDERS; BLOOD; GENETICS; METABOLISM; MIDDLE AGED; MONONUCLEAR CELL; PSYCHOLOGY; REAL TIME POLYMERASE CHAIN REACTION; REFERENCE VALUE; STATISTICS;

ADULT; ANXIETY DISORDERS; FEMALE; HUMANS; LEUKOCYTES, MONONUCLEAR; MALE; MICRORNAS; MIDDLE AGED; REAL-TIME POLYMERASE CHAIN REACTION; REFERENCE VALUES; STATISTICS AS TOPIC;

EID: 84976400637     PISSN: 0010440X     EISSN: 15328384     Source Type: Journal    
DOI: 10.1016/j.comppsych.2016.05.006     Document Type: Article

References (47)

1. H.U. Wittchen, F. Jacobi, J. Rehm, A. Gustavsson, M. Svensson, B. Jonsson, and et al. The size and burden of mental disorders and other disorders of the brain in Europe 2010 Eur Neuropsychopharmacol 21 2011 655 679
2. P.P. Roy-Byrne, K.W. Davidson, R.C. Kessler, G.J. Asmundson, R.D. Goodwin, L. Kubzansky, and et al. Anxiety disorders and comorbid medical illness Gen Hosp Psychiatry 30 2008 208 225
3. M.C. Palazzo, B. Dell'Osso, A.C. Altamura, D.J. Stein, and D.S. Baldwin Health literacy and the pharmacological treatment of anxiety disorders: a systematic review Hum Psychopharmacol 29 2014 211 215
4. J.C. Knight Regulatory polymorphisms underlying complex disease traits J Mol Med 83 2005 97 109
5. K. Domschke, and J. Deckert Genetics of anxiety disorders - status quo and quo vadis Curr Pharm Des 18 2012 5691 5698
6. E. Huntzinger, and E. Izaurralde Gene silencing by microRNAs: contributions of translational repression and mRNA decay Nat Rev Genet 12 2011 99 110
7. D. Baek, J. Villen, C. Shin, F.D. Camargo, S.P. Gygi, and D.P. Bartel The impact of microRNAs on protein output Nature 455 2008 64 71
8. J. Krol, I. Loedige, and W. Filipowicz The widespread regulation of microRNA biogenesis, function and decay Nat Rev Genet 11 2010 597 610
9. R. Zhou, P. Yuan, Y. Wang, J.G. Hunsberger, A. Elkahloun, Y. Wei, and et al. Evidence for selective microRNAs and their effectors as common long-term targets for the actions of mood stabilizers Neuropsychopharmacology 34 2009 1395 1405
10. J.G. Hunsberger, D.R. Austin, G. Chen, and H.K. Manji MicroRNAs in mental health: from biological underpinnings to potential therapies Neuromolecular Med 11 2009 173 182
11. C. Liu, Z.Q. Teng, N.J. Santistevan, K.E. Szulwach, W. Guo, P. Jin, and et al. Epigenetic regulation of miR-184 by MBD1 governs neural stem cell proliferation and differentiation Cell Stem Cell 6 2010 433 444
12. A.W. Kuss, and W. Chen MicroRNAs in brain function and disease Curr Neurol Neurosci Rep 8 2008 190 197
13. S. Katsuura, Y. Kuwano, N. Yamagishi, K. Kurokawa, K. Kajita, Y. Akaike, and et al. MicroRNAs miR-144/144∗and miR-16 in peripheral blood are potential biomarkers for naturalistic stress in healthy Japanese medical students Neurosci Lett 516 2012 79 84
14. H.T. Song, X.Y. Sun, L. Zhang, L. Zhao, Z.M. Guo, H.M. Fan, and et al. A preliminary analysis of association between the down-regulation of microRNA-181b expression and symptomatology improvement in schizophrenia patients before and after antipsychotic treatment J Psychiatr Res 54 2014 134 140
15. H.M. Fan, X.Y. Sun, W. Guo, A.F. Zhong, W. Niu, L. Zhao, and et al. Differential expression of microRNA in peripheral blood mononuclear cells as specific biomarker for major depressive disorder patients J Psychiatr Res 2014
16. S.J. Lupien, B.S. McEwen, M.R. Gunnar, and C. Heim Effects of stress throughout the lifespan on the brain, behaviour and cognition Nat Rev Neurosci 10 2009 434 445
17. A. Meerson, L. Cacheaux, K.A. Goosens, R.M. Sapolsky, H. Soreq, and D. Kaufer Changes in brain MicroRNAs contribute to cholinergic stress reactions J Mol Neurosci 40 2010 47 55
18. S. Uchida, A. Nishida, K. Hara, T. Kamemoto, M. Suetsugi, M. Fujimoto, and et al. Characterization of the vulnerability to repeated stress in Fischer 344 rats: possible involvement of microRNA-mediated down-regulation of the glucocorticoid receptor Eur J Neurosci 27 2008 2250 2261
19. S. Haramati, I. Navon, O. Issler, G. Ezra-Nevo, S. Gil, R. Zwang, and et al. MicroRNA as repressors of stress-induced anxiety: the case of amygdalar miR-34 J Neurosci 31 2011 14191 14203
20. G. Shaltiel, M. Hanan, Y. Wolf, S. Barbash, E. Kovalev, S. Shoham, and et al. Hippocampal microRNA-132 mediates stress-inducible cognitive deficits through its acetylcholinesterase target Brain Struct Funct 218 2013 59 72
21. L. Soreq, A. Guffanti, N. Salomonis, A. Simchovitz, Z. Israel, H. Bergman, and et al. Long non-coding RNA and alternative splicing modulations in Parkinson's leukocytes identified by RNA sequencing PLoS Comput Biol 10 2014 e1003517
22. A. Gladkevich, H.F. Kauffman, and J. Korf Lymphocytes as a neural probe: potential for studying psychiatric disorders Prog Neuropsychopharmacol Biol Psychiatry 28 2004 559 576
23. D. Marazziti, D.M. Catena, S. Baroni, I. Masala, B. Dell'Osso, G. Consoli, and et al. Alterations of the dopamine transporter in resting lymphocytes of patients with different psychotic disorders Psychiatry Res 175 2010 54 57
24. H. Rong, T.B. Liu, K.J. Yang, H.C. Yang, D.H. Wu, C.P. Liao, and et al. MicroRNA-134 plasma levels before and after treatment for bipolar mania J Psychiatr Res 45 2011 92 95
25. L. Tan, J.T. Yu, Q.Y. Liu, M.S. Tan, W. Zhang, N. Hu, and et al. Circulating miR-125b as a biomarker of Alzheimer's disease J Neurol Sci 336 2014 52 56
26. M. Hamilton The assessment of anxiety states by rating Br J Med Psychol 32 1959 50 55
27. Y. Wang, D. Zheng, Q. Tan, M.X. Wang, and L.Q. Gu Nanopore-based detection of circulating microRNAs in lung cancer patients Nat Nanotechnol 6 2011 668 674
28. H.W. Zheng, Y.L. Wang, J.X. Lin, N. Li, X.Q. Zhao, G.F. Liu, and et al. Circulating microRNAs as potential risk biomarkers for hematoma enlargement after intracerebral hemorrhage CNS Neurosci Ther 18 2012 1003 1011
29. T.D. Schmittgen, and K.J. Livak Analyzing real-time PCR data by the comparative C(T) method Nat Protoc 3 2008 1101 1108
30. B.P. Lewis, C.B. Burge, and D.P. Bartel Conserved seed pairing, often flanked by adenosines, indicates that thousands of human genes are microRNA targets Cell 120 2005 15 20
31. G.M. Schratt, F. Tuebing, E.A. Nigh, C.G. Kane, M.E. Sabatini, M. Kiebler, and et al. A brain-specific microRNA regulates dendritic spine development Nature 439 2006 283 289
32. N. Vo, M.E. Klein, O. Varlamova, D.M. Keller, T. Yamamoto, R.H. Goodman, and et al. A cAMP-response element binding protein-induced microRNA regulates neuronal morphogenesis Proc Natl Acad Sci U S A 102 2005 16426 16431
33. S. Malan-Muller, S.M. Hemmings, and S. Seedat Big effects of small RNAs: a review of microRNAs in anxiety Mol Neurobiol 47 2013 726 739
34. M. Honda, Y. Kuwano, S. Katsuura-Kamano, Y. Kamezaki, K. Fujita, Y. Akaike, and et al. Chronic academic stress increases a group of microRNAs in peripheral blood PLoS One 8 2013 e75960
35. O. Issler, S. Haramati, E.D. Paul, H. Maeno, I. Navon, R. Zwang, and et al. MicroRNA 135 is essential for chronic stress resiliency, antidepressant efficacy, and intact serotonergic activity Neuron 83 2014 344 360
36. J. Chen, D. Yao, Y. Li, H. Chen, C. He, N. Ding, and et al. Serum microRNA expression levels can predict lymph node metastasis in patients with early-stage cervical squamous cell carcinoma Int J Mol Med 32 2013 557 567
37. I. Surgucheva, S. Gunewardena, H.S. Rao, and A. Surguchov Cell-specific post-transcriptional regulation of gamma-synuclein gene by micro-RNAs PLoS One 8 2013 e73786
38. N.A. Serrano, C. Xu, Y. Liu, P. Wang, W. Fan, M.P. Upton, and et al. Integrative analysis in oral squamous cell carcinoma reveals DNA copy number-associated miRNAs dysregulating target genes Otolaryngol Head Neck Surg 147 2012 501 508
39. S. Liu, F. Yin, J. Zhang, M.S. Wicha, A.E. Chang, W. Fan, and et al. Regulatory roles of miRNA in the human neural stem cell transformation to glioma stem cells J Cell Biochem 115 2014 1368 1380
40. J.L. Liu, X.H. Liang, R.W. Su, W. Lei, B. Jia, X.H. Feng, and et al. Combined analysis of microRNome and 3'-UTRome reveals a species-specific regulation of progesterone receptor expression in the endometrium of rhesus monkey J Biol Chem 287 2012 13899 13910
41. G.M. Sundaram, J.E. Common, F.E. Gopal, S. Srikanta, K. Lakshman, D.P. Lunny, and et al. 'See-saw' expression of microRNA-198 and FSTL1 from a single transcript in wound healing Nature 495 2013 103 106
42. M.E. Waaijer, M. Wieser, R. Grillari-Voglauer, D. van Heemst, J. Grillari, and A.B. Maier MicroRNA-663 induction upon oxidative stress in cultured human fibroblasts depends on the chronological age of the donor Biogerontology 15 2014 269 278
43. O.C. Maes, H. Sarojini, and E. Wang Stepwise up-regulation of microRNA expression levels from replicating to reversible and irreversible growth arrest states in WI-38 human fibroblasts J Cell Physiol 221 2009 109 119
44. M. Hackl, S. Brunner, K. Fortschegger, C. Schreiner, L. Micutkova, C. Muck, and et al. miR-17, miR-19b, miR-20a, and miR-106a are down-regulated in human aging Aging Cell 9 2010 291 296
45. E. Borgan, R. Navon, H.K. Vollan, E. Schlichting, T. Sauer, Z. Yakhini, and et al. Ischemia caused by time to freezing induces systematic microRNA and mRNA responses in cancer tissue Mol Oncol 5 2011 564 576
46. H.M. Fan, W. Nui, M.J. He, A.F. Zhong, Q.L. Zhang, Y. Yan, and et al. Bioinformatiics analysis of differently expressed microRNAs in anxiety disiorder Chin J Med Genet 32 2015 641 646
47. G. Hanin, S. Shenhar-Tsarfaty, N. Yayon, Y.H. Yau, Y.Y. Hoe, E.R. Bennett, and et al. Competing targets of microRNA-608 affect anxiety and hypertension Hum Mol Genet 23 2014 4569 4580