-
1
-
-
34249669270
-
Sirt1 regulates aging and resistance to oxidative stress in the heart
-
Alcendor RR, Gao S, Zhai P, Zabłocki D, Holle E, Yu X, Tian B, Wagner T, Vatner SF, Sadoshima J (2007) Sirt1 regulates aging and resistance to oxidative stress in the heart. Circ Res 100:1512-1521
-
(2007)
Circ Res
, vol.100
, pp. 1512-1521
-
-
Alcendor, R.R.1
Gao, S.2
Zhai, P.3
Zabłocki, D.4
Holle, E.5
Yu, X.6
Tian, B.7
Wagner, T.8
Vatner, S.F.9
Sadoshima, J.10
-
2
-
-
79952265105
-
Gender differences in metformin effect on aging, life span and spontaneous tumorigenesis in 129/Sv mice
-
Anisimov VN, Piskunova TS, Popovich IG, Zabezhinski MA, Tyndyk ML, Egormin PA, Yurova MV, Rosenfeld SV, Semenchenko AV, Kovalenko IG et al (2010) Gender differences in metformin effect on aging, life span and spontaneous tumorigenesis in 129/Sv mice. Aging (Albany NY) 2:945-958
-
(2010)
Aging (Albany NY)
, vol.2
, pp. 945-958
-
-
Anisimov, V.N.1
Piskunova, T.S.2
Popovich, I.G.3
Zabezhinski, M.A.4
Tyndyk, M.L.5
Egormin, P.A.6
Yurova, M.V.7
Rosenfeld, S.V.8
Semenchenko, A.V.9
Kovalenko, I.G.10
-
3
-
-
48349110303
-
A low dose of dietary resveratrol partially mimics caloric restriction and retards aging parameters in mice
-
Barger JL, Kayo T, Vann JM, Arias EB, Wang J, Hacker TA, Wang Y, Raederstorff D, Morrow JD, Leeuwenburgh C et al (2008) A low dose of dietary resveratrol partially mimics caloric restriction and retards aging parameters in mice. PLoS One 3:e2264
-
(2008)
PLoS One
, vol.3
, pp. e2264
-
-
Barger, J.L.1
Kayo, T.2
Vann, J.M.3
Arias, E.B.4
Wang, J.5
Hacker, T.A.6
Wang, Y.7
Raederstorff, D.8
Morrow, J.D.9
Leeuwenburgh, C.10
-
4
-
-
10744228523
-
Adult cardiac stem cells are multipotent and support myocardial regeneration
-
Beltrami AP, Barlucchi L, Torella D, Baker M, Limana F, Chimenti S, Kasahara H, Rota M, Musso E, Urbanek K et al (2003) Adult cardiac stem cells are multipotent and support myocardial regeneration. Cell 114:763-776.
-
(2003)
Cell
, vol.114
, pp. 763-776
-
-
Beltrami, A.P.1
Barlucchi, L.2
Torella, D.3
Baker, M.4
Limana, F.5
Chimenti, S.6
Kasahara, H.7
Rota, M.8
Musso, E.9
Urbanek, K.10
-
5
-
-
41149107026
-
Aging-related defects are associated with adverse cardiac remodeling in a mouse model of reperfused myocardial infarction
-
Bujak M, Kweon HJ, Chatila K, Li N, Taffet G, Frangogiannis NG (2008) Aging-related defects are associated with adverse cardiac remodeling in a mouse model of reperfused myocardial infarction. J Am Coll Cardiol 51:1384-1392
-
(2008)
J Am Coll Cardiol
, vol.51
, pp. 1384-1392
-
-
Bujak, M.1
Kweon, H.J.2
Chatila, K.3
Li, N.4
Taffet, G.5
Frangogiannis, N.G.6
-
6
-
-
0032145716
-
Human SERCA2a levels correlate inversely with age in senescent human myocardium
-
Cain BS, Meldrum DR, Joo KS, Wang JF, Meng X, Cleveland JC Jr, Banerjee A, Harken AH (1998) Human SERCA2a levels correlate inversely with age in senescent human myocardium. J Am Coll Cardiol 32:458-467
-
(1998)
J Am Coll Cardiol
, vol.32
, pp. 458-467
-
-
Cain, B.S.1
Meldrum, D.R.2
Joo, K.S.3
Wang, J.F.4
Meng, X.5
Cleveland, J.C.6
Banerjee, A.7
Harken, A.H.8
-
7
-
-
18244378576
-
Age-related death-survival balance in myocardium: An immunohistochemical and biochemical study
-
Centurione L, Antonucci A, Miscia S, Grilli A, Rapino M, Grifone G, Di Giacomo V, Di Giulio C, Falconi M, Cataldi A (2002) Age-related death-survival balance in myocardium: an immunohistochemical and biochemical study. Mech Ageing Dev 123:341-350
-
(2002)
Mech Ageing Dev
, vol.123
, pp. 341-350
-
-
Centurione, L.1
Antonucci, A.2
Miscia, S.3
Grilli, A.4
Rapino, M.5
Grifone, G.6
Di Giacomo, V.7
Di Giulio, C.8
Falconi, M.9
Cataldi, A.10
-
8
-
-
34548421482
-
Systolic and diastolic heart failure: Differences and similarities
-
Chatterjee K, Massie B (2007) Systolic and diastolic heart failure: differences and similarities. J Card Fail 13:569-576
-
(2007)
J Card Fail
, vol.13
, pp. 569-576
-
-
Chatterjee, K.1
Massie, B.2
-
9
-
-
33645987888
-
Gene expression and physiologic responses of the heart to the initiation and withdrawal of caloric restriction
-
Dhahbi JM, Tsuchiya T, Kim HJ, Mote PL, Spindler SR (2006) Gene expression and physiologic responses of the heart to the initiation and withdrawal of caloric restriction. J Gerontol A Biol Sci Med Sci 61:218-231
-
(2006)
J Gerontol A Biol Sci Med Sci
, vol.61
, pp. 218-231
-
-
Dhahbi, J.M.1
Tsuchiya, T.2
Kim, H.J.3
Mote, P.L.4
Spindler, S.R.5
-
10
-
-
84859896427
-
Contribution of impaired mitochondrial autophagy to cardiac aging: Mechanisms and therapeutic opportunities
-
Dutta D, Calvani R, Bernabei R, Leeuwenburgh C, Marzetti E (2012) Contribution of impaired mitochondrial autophagy to cardiac aging: mechanisms and therapeutic opportunities. Circ Res 110:1125-1138
-
(2012)
Circ Res
, vol.110
, pp. 1125-1138
-
-
Dutta, D.1
Calvani, R.2
Bernabei, R.3
Leeuwenburgh, C.4
Marzetti, E.5
-
11
-
-
50949116173
-
Prolonged caloric restriction in obese patients with type 2 diabetes mellitus decreases myocardial triglyceride content and improves myocardial function
-
Hammer S, Snel M, Lamb HJ, Jazet IM, van der Meer RW, Pijl H, Meinders EA, Romijn JA, de Roos A, Smit JW (2008) Prolonged caloric restriction in obese patients with type 2 diabetes mellitus decreases myocardial triglyceride content and improves myocardial function. J Am Coll Cardiol 52:1006-1012
-
(2008)
J Am Coll Cardiol
, vol.52
, pp. 1006-1012
-
-
Hammer, S.1
Snel, M.2
Lamb, H.J.3
Jazet, I.M.4
van der Meer, R.W.5
Pijl, H.6
Meinders, E.A.7
Romijn, J.A.8
de Roos, A.9
Smit, J.W.10
-
12
-
-
33947401070
-
Autophagy regulates ageing in C
-
Hars ES, Qi H, Ryazanov AG, Jin S, Cai L, Hu C, Liu LF (2007) Autophagy regulates ageing in C. elegans. Autophagy 3:93-95
-
(2007)
elegans. Autophagy
, vol.3
, pp. 93-95
-
-
Hars, E.S.1
Qi, H.2
Ryazanov, A.G.3
Jin, S.4
Cai, L.5
Hu, C.6
Liu, L.F.7
-
13
-
-
84875450015
-
Dissociation of Bcl-2-Bedin1 complex by activated AMPK enhances cardiac autophagy and protects against cardiomyocyte apoptosis in diabetes
-
He C, Zhu H, Li H, Zou MH, Xie Z (2013) Dissociation of Bcl-2-Bedin1 complex by activated AMPK enhances cardiac autophagy and protects against cardiomyocyte apoptosis in diabetes. Diabetes 62:1270-1281
-
(2013)
Diabetes
, vol.62
, pp. 1270-1281
-
-
He, C.1
Zhu, H.2
Li, H.3
Zou, M.H.4
Xie, Z.5
-
14
-
-
70350540920
-
Suppression of phosphoinositide 3-kinase prevents cardiac aging in mice
-
Inuzuka Y, Okuda J, Kawashima T, Kato T, Niizuma S, Tamaki Y, Iwanaga Y, Yoshida Y, Kosugi R, Watanabe-Maeda K et al (2009) Suppression of phosphoinositide 3-kinase prevents cardiac aging in mice. Circulation 120:1695-1703
-
(2009)
Circulation
, vol.120
, pp. 1695-1703
-
-
Inuzuka, Y.1
Okuda, J.2
Kawashima, T.3
Kato, T.4
Niizuma, S.5
Tamaki, Y.6
Iwanaga, Y.7
Yoshida, Y.8
Kosugi, R.9
Watanabe-Maeda, K.10
-
15
-
-
35848937781
-
Autophagy is required for dietary restriction-mediated life span extension in C
-
Jia K, Levine B (2007) Autophagy is required for dietary restriction-mediated life span extension in C. elegans. Autophagy 3:597-599
-
(2007)
elegans. Autophagy
, vol.3
, pp. 597-599
-
-
Jia, K.1
Levine, B.2
-
16
-
-
78650419568
-
Myocyte turnover in the aging human heart
-
Kajstura J, Gurusamy N, Ogorek B, Goichberg P, Clavo-Rondon C, Hosoda T, D'Amario D, Bardelli S, Beltrami AP, Cesselli D et al (2010) Myocyte turnover in the aging human heart. Circ Res 107:1374-1386
-
(2010)
Circ Res
, vol.107
, pp. 1374-1386
-
-
Kajstura, J.1
Gurusamy, N.2
Ogorek, B.3
Goichberg, P.4
Clavo-Rondon, C.5
Hosoda, T.6
D'Amario, D.7
Bardelli, S.8
Beltrami, A.P.9
Cesselli, D.10
-
17
-
-
0037469206
-
Arterial and cardiac aging: Major shareholders in cardiovascular disease enterprises: Part III: Cellular and molecular clues to heart and arterial aging
-
Lakatta EG (2003) Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: part III: cellular and molecular clues to heart and arterial aging. Circulation 107:490-497
-
(2003)
Circulation
, vol.107
, pp. 490-497
-
-
Lakatta, E.G.1
-
18
-
-
0037458070
-
Arterial and cardiac aging: Major shareholders in cardiovascular disease enterprises: Part II: The aging heart in health: Links to heart disease
-
Lakatta EG, Levy D (2003) Arterial and cardiac aging: major shareholders in cardiovascular disease enterprises: part II: the aging heart in health: links to heart disease. Circulation 107:346-354
-
(2003)
Circulation
, vol.107
, pp. 346-354
-
-
Lakatta, E.G.1
Levy, D.2
-
20
-
-
52449102483
-
Cardiac dysfunction in aging conscious rats: Altered cardiac cytoskeletal proteins as a potential mechanism
-
Lieber SC, Qiu H, Chen L, Shen YT, Hong C, Hunter WC, Aubry N, Vatner SF, Vatner DE (2008) Cardiac dysfunction in aging conscious rats: altered cardiac cytoskeletal proteins as a potential mechanism. Am J Physiol Heart Circ Physiol 295:H860-H866
-
(2008)
Am J Physiol Heart Circ Physiol
, vol.295
, pp. H860-H866
-
-
Lieber, S.C.1
Qiu, H.2
Chen, L.3
Shen, Y.T.4
Hong, C.5
Hunter, W.C.6
Aubry, N.7
Vatner, S.F.8
Vatner, D.E.9
-
21
-
-
16344385466
-
Age-dependent changes in myocardial matrix metalloprotein-ase/tissue inhibitor of metalloproteinase profiles and fibroblast function
-
Lindsey ML, Goshorn DK, Squires CE, Escobar GP, Hendrick JW, Mingoia JT, Sweterlitsch SE, Spinale FG (2005) Age-dependent changes in myocardial matrix metalloprotein-ase/tissue inhibitor of metalloproteinase profiles and fibroblast function. Cardiovasc Res 66:410-419
-
(2005)
Cardiovasc Res
, vol.66
, pp. 410-419
-
-
Lindsey, M.L.1
Goshorn, D.K.2
Squires, C.E.3
Escobar, G.P.4
Hendrick, J.W.5
Mingoia, J.T.6
Sweterlitsch, S.E.7
Spinale, F.G.8
-
22
-
-
3042608187
-
Inhibition of mTOR signaling with rapamycin regresses established cardiac hypertrophy induced by pressure overload
-
McMullen JR, Sherwood MC, Tarnavski O, Zhang L, Dorfman AL, Shioi T, Izumo S (2004) Inhibition of mTOR signaling with rapamycin regresses established cardiac hypertrophy induced by pressure overload. Circulation 109:3050-3055
-
(2004)
Circulation
, vol.109
, pp. 3050-3055
-
-
McMullen, J.R.1
Sherwood, M.C.2
Tarnavski, O.3
Zhang, L.4
Dorfman, A.L.5
Shioi, T.6
Izumo, S.7
-
23
-
-
30344435943
-
Long-term caloric restriction ameliorates the decline in diastolic function in humans
-
Meyer TE, Kovacs SJ, Ehsani AA, Klein S, Holloszy JO, Fontana L (2006) Long-term caloric restriction ameliorates the decline in diastolic function in humans. J Am Coll Cardiol 47:398-402
-
(2006)
J Am Coll Cardiol
, vol.47
, pp. 398-402
-
-
Meyer, T.E.1
Kovacs, S.J.2
Ehsani, A.A.3
Klein, S.4
Holloszy, J.O.5
Fontana, L.6
-
24
-
-
0030766192
-
Apoptosis in the failing human heart
-
Olivetti G, Abbi R, Quaini F, Kajstura J, Cheng W, Nitahara JA, Quaini E, Di Loreto C, Beltrami CA, Krajewski S et al (1997) Apoptosis in the failing human heart. N Engl J Med 336:1131-1141
-
(1997)
N Engl J Med
, vol.336
, pp. 1131-1141
-
-
Olivetti, G.1
Abbi, R.2
Quaini, F.3
Kajstura, J.4
Cheng, W.5
Nitahara, J.A.6
Quaini, E.7
Di Loreto, C.8
Beltrami, C.A.9
Krajewski, S.10
-
26
-
-
79951812916
-
Telomere dysfunction induces metabolic and mitochondrial compromise
-
Sahin E, Colla S, Liesa M, Moslehi J, Muller FL, Guo M, Cooper M, Kotton D, Fabian AJ, Walkey C et al (2011) Telomere dysfunction induces metabolic and mitochondrial compromise. Nature 470:359-365
-
(2011)
Nature
, vol.470
, pp. 359-365
-
-
Sahin, E.1
Colla, S.2
Liesa, M.3
Moslehi, J.4
Muller, F.L.5
Guo, M.6
Cooper, M.7
Kotton, D.8
Fabian, A.J.9
Walkey, C.10
-
27
-
-
0034701045
-
Restoration of diastolic function in senescent rat hearts through adenoviral gene transfer of sarcoplasmic reticulum Ca(2+)-ATPase
-
Schmidt U, del Monte F, Miyamoto MI, Matsui T, Gwathmey JK, Rosenzweig A, Hajjar RJ (2000) Restoration of diastolic function in senescent rat hearts through adenoviral gene transfer of sarcoplasmic reticulum Ca(2+)-ATPase. Circulation 101:790-796
-
(2000)
Circulation
, vol.101
, pp. 790-796
-
-
Schmidt, U.1
del Monte, F.2
Miyamoto, M.I.3
Matsui, T.4
Gwathmey, J.K.5
Rosenzweig, A.6
Hajjar, R.J.7
-
28
-
-
78650611093
-
The aging heart and post-infarction left ventricular remodeling
-
Shih H, Lee B, Lee RJ, Boyle AJ (2011) The aging heart and post-infarction left ventricular remodeling. J Am Coll Cardiol 57:9-17
-
(2011)
J Am Coll Cardiol
, vol.57
, pp. 9-17
-
-
Shih, H.1
Lee, B.2
Lee, R.J.3
Boyle, A.J.4
-
29
-
-
84876522971
-
Effects of caloric restriction on cardiac oxidative stress and mitochondrial bioenergetics: Potential role of cardiac sirtuins
-
Shinmura K (2013) Effects of caloric restriction on cardiac oxidative stress and mitochondrial bioenergetics: potential role of cardiac sirtuins. Oxid Med Cell Longev 2013:528-935
-
(2013)
Oxid Med Cell Longev
, vol.2013
, pp. 528-935
-
-
Shinmura, K.1
-
30
-
-
78650835776
-
Impact of long-term caloric restriction on cardiac senescence: Caloric restriction ameliorates cardiac diastolic dysfunction associated with aging
-
Shinmura K, Tamaki K, Sano M, Murata M, Yamakawa H, Ishida H, Fukuda K (2011) Impact of long-term caloric restriction on cardiac senescence: caloric restriction ameliorates cardiac diastolic dysfunction associated with aging. J Mol Cell Cardiol 50:117-127
-
(2011)
J Mol Cell Cardiol
, vol.50
, pp. 117-127
-
-
Shinmura, K.1
Tamaki, K.2
Sano, M.3
Murata, M.4
Yamakawa, H.5
Ishida, H.6
Fukuda, K.7
-
32
-
-
0031438474
-
The age-associated alterations in late diastolic function in mice are improved by caloric restriction
-
Taffet GE, Pham TT, Hartley CJ (1997) The age-associated alterations in late diastolic function in mice are improved by caloric restriction. J Gerontol A Biol Sci Med Sci 52:B285-B290
-
(1997)
J Gerontol A Biol Sci Med Sci
, vol.52
, pp. B285-B290
-
-
Taffet, G.E.1
Pham, T.T.2
Hartley, C.J.3
-
33
-
-
77955342581
-
Inhibition of autophagy in the heart induces age-related cardiomyopathy
-
Taneike M, Yamaguchi O, Nakai A, Hikoso S, Takeda T, Mizote I, Oka T, Tamai T, Oyabu J, Murakawa T et al (2010) Inhibition of autophagy in the heart induces age-related cardiomyopathy. Autophagy 6:600-606
-
(2010)
Autophagy
, vol.6
, pp. 600-606
-
-
Taneike, M.1
Yamaguchi, O.2
Nakai, A.3
Hikoso, S.4
Takeda, T.5
Mizote, I.6
Oka, T.7
Tamai, T.8
Oyabu, J.9
Murakawa, T.10
-
34
-
-
34548512483
-
Autophagy in the heart and liver during normal aging and calorie restriction
-
Wohlgemuth SE, Julian D, Akin DE, Fried J, Toscano K, Leeuwenburgh C, Dunn WA Jr (2007) Autophagy in the heart and liver during normal aging and calorie restriction. Rejuvenation Res 10:281-292
-
(2007)
Rejuvenation Res
, vol.10
, pp. 281-292
-
-
Wohlgemuth, S.E.1
Julian, D.2
Akin, D.E.3
Fried, J.4
Toscano, K.5
Leeuwenburgh, C.6
Dunn, W.A.7
|