Genetic defects in a His-Purkinje system transcription factor, IRX3, cause lethal cardiac arrhythmias

European Heart Journal

Volumn 37, Issue 18, 2016, Pages 1469-1475

  Koizumi, Akiko ^a   Sasano, Tetsuo ^a   Kimura, Wataru ^b   Miyamoto, Yoshihiro ^c   Aiba, Takeshi ^c   Ishikawa, Taisuke ^a   Nogami, Akihiko ^d   Fukamizu, Seiji ^e   Sakurada, Harumizu ^e   Takahashi, Yoshihide ^f   Nakamura, Hiroaki ^g   Ishikura, Tomoyuki ^h   Koseki, Haruhiko ^h   Arimura, Takuro ^a   Kimura, Akinori ^a   Hirao, Kenzo ^a,i   Isobe, Mitsuaki ⁱ   Shimizu, Wataru ^c,j   Miura, Naoyuki ^b   Furukawa, Tetsushi ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b HAMAMATSU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

^d YOKOHAMA ROSAI HOSPITAL   (Japan)

^e TOKYO METROPOLITAN HIROO HOSPITAL   (Japan)

^f YOKOSUKA KYOSAI HOSPITAL   (Japan)

^g Hiratsuka Kyosai Hospital   (Japan)

^h RIKEN   (Japan)

ⁱ TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^j NIPPON MEDICAL SCHOOL   (Japan)

more..

Author keywords

Cardiac conduction system; Sudden cardiac death; Ventricular fibrillation

Indexed keywords

CONNEXIN 40; MESSENGER RNA; SODIUM CHANNEL NAV1.5; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR IRX3; UNCLASSIFIED DRUG; HOMEODOMAIN PROTEIN; IRX3 PROTEIN, HUMAN; IRX3 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARRHYTHMOGENESIS; ARTICLE; CARDIAC MUSCLE CELL; CONTROLLED STUDY; ELECTROCARDIOGRAPHY; EXERCISE; EXON; GENE MUTATION; GENETIC DISORDER; GENETIC SCREENING; GENETIC TRANSFECTION; HEART VENTRICLE FIBRILLATION; HEART VENTRICLE PRESSURE; HEART VENTRICLE TACHYCARDIA; HIS BUNDLE; HIS PURKINJE SYSTEM; IDIOPATHIC DISEASE; MOUSE; NEWBORN; NONHUMAN; PRIORITY JOURNAL; PURKINJE FIBER; SEQUENCE ANALYSIS; SYMPATHETIC NERVE; UPREGULATION; ANIMAL; HEART ARRHYTHMIA; HEART MUSCLE CONDUCTION SYSTEM; HUMAN; SUDDEN CARDIAC DEATH;

ANIMALS; ARRHYTHMIAS, CARDIAC; DEATH, SUDDEN, CARDIAC; HEART CONDUCTION SYSTEM; HOMEODOMAIN PROTEINS; HUMANS; MICE; TRANSCRIPTION FACTORS; VENTRICULAR FIBRILLATION;

EID: 84975879537     PISSN: 0195668X     EISSN: 15229645     Source Type: Journal    
DOI: 10.1093/eurheartj/ehv449     Document Type: Article

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