-
1
-
-
84890738424
-
Updated clinical classification of pulmonary hypertension
-
Simonneau G, Gatzoulis MA, Adatia I, et al. Updated clinical classification of pulmonary hypertension. J Am Coll Cardiol 2013, 62:D34-D41.
-
(2013)
J Am Coll Cardiol
, vol.62
, pp. D34-D41
-
-
Simonneau, G.1
Gatzoulis, M.A.2
Adatia, I.3
-
2
-
-
84943272997
-
2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension
-
Galiè N, Humbert M, Vachiery J-L, et al. 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension. Eur Respir J 2015, 46:903-975.
-
(2015)
Eur Respir J
, vol.46
, pp. 903-975
-
-
Galiè, N.1
Humbert, M.2
Vachiery, J.-L.3
-
3
-
-
4644290657
-
Treatment of pulmonary arterial hypertension
-
Humbert M, Sitbon O, Simonneau G Treatment of pulmonary arterial hypertension. N Engl J Med 2004, 351:1425-1436.
-
(2004)
N Engl J Med
, vol.351
, pp. 1425-1436
-
-
Humbert, M.1
Sitbon, O.2
Simonneau, G.3
-
4
-
-
4544383466
-
Combination of bosentan with epoprostenol in pulmonary arterial hypertension: BREATHE-2
-
Humbert M, Barst RJ, Robbins IM, et al. Combination of bosentan with epoprostenol in pulmonary arterial hypertension: BREATHE-2. Eur Respir J 2004, 24:353-359.
-
(2004)
Eur Respir J
, vol.24
, pp. 353-359
-
-
Humbert, M.1
Barst, R.J.2
Robbins, I.M.3
-
5
-
-
84880721470
-
Riociguat for the treatment of pulmonary arterial hypertension
-
Ghofrani H-A, Galiè N, Grimminger F, et al. Riociguat for the treatment of pulmonary arterial hypertension. N Engl J Med 2013, 369:330-340.
-
(2013)
N Engl J Med
, vol.369
, pp. 330-340
-
-
Ghofrani, H.-A.1
Galiè, N.2
Grimminger, F.3
-
6
-
-
84890574392
-
Updated treatment algorithm of pulmonary arterial hypertension
-
Galiè N, Corris PA, Frost A, et al. Updated treatment algorithm of pulmonary arterial hypertension. J Am Coll Cardiol 2013, 62:D60-D72.
-
(2013)
J Am Coll Cardiol
, vol.62
, pp. D60-D72
-
-
Galiè, N.1
Corris, P.A.2
Frost, A.3
-
7
-
-
84863528040
-
Selexipag: an oral, selective prostacyclin receptor agonist for the treatment of pulmonary arterial hypertension
-
Simonneau G, Torbicki A, Hoeper MM, et al. Selexipag: an oral, selective prostacyclin receptor agonist for the treatment of pulmonary arterial hypertension. Eur Respir J 2012, 40:874-880.
-
(2012)
Eur Respir J
, vol.40
, pp. 874-880
-
-
Simonneau, G.1
Torbicki, A.2
Hoeper, M.M.3
-
8
-
-
67649588196
-
Updated evidence-based treatment algorithm in pulmonary arterial hypertension
-
Barst RJ, Gibbs JSR, Ghofrani HA, et al. Updated evidence-based treatment algorithm in pulmonary arterial hypertension. J Am Coll Cardiol 2009, 54:S78-S84.
-
(2009)
J Am Coll Cardiol
, vol.54
, pp. S78-S84
-
-
Barst, R.J.1
Gibbs, J.S.R.2
Ghofrani, H.A.3
-
9
-
-
62749192201
-
A meta-analysis of randomized controlled trials in pulmonary arterial hypertension
-
Galiè N, Manes A, Negro L, Palazzini M, Bacchi-Reggiani ML, Branzi A A meta-analysis of randomized controlled trials in pulmonary arterial hypertension. Eur Heart J 2009, 30:394-403.
-
(2009)
Eur Heart J
, vol.30
, pp. 394-403
-
-
Galiè, N.1
Manes, A.2
Negro, L.3
Palazzini, M.4
Bacchi-Reggiani, M.L.5
Branzi, A.6
-
10
-
-
77955953602
-
Survival in incident and prevalent cohorts of patients with pulmonary arterial hypertension
-
Humbert M, Sitbon O, Yaïci A, et al. Survival in incident and prevalent cohorts of patients with pulmonary arterial hypertension. Eur Respir J 2010, 36:549-555.
-
(2010)
Eur Respir J
, vol.36
, pp. 549-555
-
-
Humbert, M.1
Sitbon, O.2
Yaïci, A.3
-
11
-
-
77954758530
-
Survival in patients with idiopathic, familial, and anorexigen-associated pulmonary arterial hypertension in the modern management era
-
Humbert M, Sitbon O, Chaouat A, et al. Survival in patients with idiopathic, familial, and anorexigen-associated pulmonary arterial hypertension in the modern management era. Circulation 2010, 122:156-163.
-
(2010)
Circulation
, vol.122
, pp. 156-163
-
-
Humbert, M.1
Sitbon, O.2
Chaouat, A.3
-
12
-
-
84860404865
-
Meta-analysis of monotherapy versus combination therapy for pulmonary arterial hypertension
-
Fox BD, Shimony A, Langleben D Meta-analysis of monotherapy versus combination therapy for pulmonary arterial hypertension. Am J Cardiol 2011, 108:1177-1182.
-
(2011)
Am J Cardiol
, vol.108
, pp. 1177-1182
-
-
Fox, B.D.1
Shimony, A.2
Langleben, D.3
-
13
-
-
33847368988
-
Combining inhaled iloprost with bosentan in patients with idiopathic pulmonary arterial hypertension
-
Hoeper MM, Leuchte H, Halank M, et al. Combining inhaled iloprost with bosentan in patients with idiopathic pulmonary arterial hypertension. Eur Respir J 2006, 28:691-694.
-
(2006)
Eur Respir J
, vol.28
, pp. 691-694
-
-
Hoeper, M.M.1
Leuchte, H.2
Halank, M.3
-
14
-
-
33845526777
-
Randomized study of adding inhaled iloprost to existing bosentan in pulmonary arterial hypertension
-
McLaughlin VV, Oudiz RJ, Frost A, et al. Randomized study of adding inhaled iloprost to existing bosentan in pulmonary arterial hypertension. Am J Respir Crit Care Med 2006, 174:1257-1263.
-
(2006)
Am J Respir Crit Care Med
, vol.174
, pp. 1257-1263
-
-
McLaughlin, V.V.1
Oudiz, R.J.2
Frost, A.3
-
15
-
-
54549125950
-
Addition of sildenafil to long-term intravenous epoprostenol therapy in patients with pulmonary arterial hypertension: a randomized trial
-
Simonneau G, Rubin LJ, Galiè N, et al. Addition of sildenafil to long-term intravenous epoprostenol therapy in patients with pulmonary arterial hypertension: a randomized trial. Ann Intern Med 2008, 149:521-530.
-
(2008)
Ann Intern Med
, vol.149
, pp. 521-530
-
-
Simonneau, G.1
Rubin, L.J.2
Galiè, N.3
-
16
-
-
77952301237
-
Addition of inhaled treprostinil to oral therapy for pulmonary arterial hypertension: a randomized controlled clinical trial
-
McLaughlin VV, Benza RL, Rubin LJ, et al. Addition of inhaled treprostinil to oral therapy for pulmonary arterial hypertension: a randomized controlled clinical trial. J Am Coll Cardiol 2010, 55:1915-1922.
-
(2010)
J Am Coll Cardiol
, vol.55
, pp. 1915-1922
-
-
McLaughlin, V.V.1
Benza, R.L.2
Rubin, L.J.3
-
17
-
-
67649523052
-
Tadalafil therapy for pulmonary arterial hypertension
-
Galiè N, Brundage BH, Ghofrani HA, et al. Tadalafil therapy for pulmonary arterial hypertension. Circulation 2009, 119:2894-2903.
-
(2009)
Circulation
, vol.119
, pp. 2894-2903
-
-
Galiè, N.1
Brundage, B.H.2
Ghofrani, H.A.3
-
18
-
-
84863984607
-
Validation of 6-minute walk distance as a surrogate end point in pulmonary arterial hypertension trials
-
Gabler NB, French B, Strom BL, et al. Validation of 6-minute walk distance as a surrogate end point in pulmonary arterial hypertension trials. Circulation 2012, 126:349-356.
-
(2012)
Circulation
, vol.126
, pp. 349-356
-
-
Gabler, N.B.1
French, B.2
Strom, B.L.3
-
19
-
-
84866362803
-
Do changes of 6-minute walk distance predict clinical events in patients with pulmonary arterial hypertension? A meta-analysis of 22 randomized trials
-
Savarese G, Paolillo S, Costanzo P, et al. Do changes of 6-minute walk distance predict clinical events in patients with pulmonary arterial hypertension? A meta-analysis of 22 randomized trials. J Am Coll Cardiol 2012, 60:1192-1201.
-
(2012)
J Am Coll Cardiol
, vol.60
, pp. 1192-1201
-
-
Savarese, G.1
Paolillo, S.2
Costanzo, P.3
-
20
-
-
84874027381
-
Baseline and follow-up 6-min walk distance and brain natriuretic peptide predict 2-year mortality in pulmonary arterial hypertension
-
Fritz JS, Blair C, Oudiz RJ, et al. Baseline and follow-up 6-min walk distance and brain natriuretic peptide predict 2-year mortality in pulmonary arterial hypertension. Chest 2013, 143:315.
-
(2013)
Chest
, vol.143
, pp. 315
-
-
Fritz, J.S.1
Blair, C.2
Oudiz, R.J.3
-
21
-
-
0028895409
-
Methodologic guidelines for systematic reviews of randomized control trials in health care from the Potsdam Consultation on Meta-Analysis
-
Cook DJ, Sackett DL, Spitzer WO Methodologic guidelines for systematic reviews of randomized control trials in health care from the Potsdam Consultation on Meta-Analysis. J Clin Epidemiol 1995, 48:167-171.
-
(1995)
J Clin Epidemiol
, vol.48
, pp. 167-171
-
-
Cook, D.J.1
Sackett, D.L.2
Spitzer, W.O.3
-
22
-
-
0019432398
-
Clinical biostatistics. LIV. The biostatistics of concordance
-
Kramer MS, Feinstein AR Clinical biostatistics. LIV. The biostatistics of concordance. Clin Pharmacol Ther 1981, 29:111-123.
-
(1981)
Clin Pharmacol Ther
, vol.29
, pp. 111-123
-
-
Kramer, M.S.1
Feinstein, A.R.2
-
23
-
-
84859001212
-
The Cochrane Collaboration's tool for assessing risk of bias in randomised trials
-
Higgins JPT, Altman DG, Gøtzsche PC, et al. The Cochrane Collaboration's tool for assessing risk of bias in randomised trials. BMJ 2011, 343:d5928.
-
(2011)
BMJ
, vol.343
, pp. d5928
-
-
Higgins, J.P.T.1
Altman, D.G.2
Gøtzsche, P.C.3
-
24
-
-
67649574735
-
End points and clinical trial design in pulmonary arterial hypertension
-
McLaughlin VV, Badesch DB, Delcroix M, et al. End points and clinical trial design in pulmonary arterial hypertension. J Am Coll Cardiol 2009, 54:S97-107.
-
(2009)
J Am Coll Cardiol
, vol.54
, pp. S97-107
-
-
McLaughlin, V.V.1
Badesch, D.B.2
Delcroix, M.3
-
25
-
-
84926434654
-
Estimating the sample mean and standard deviation from the sample size, median, range and/or interquartile range
-
Wan X, Wang W, Liu J, Tong T Estimating the sample mean and standard deviation from the sample size, median, range and/or interquartile range. BMC Med Res Methodol 2014, 14:135.
-
(2014)
BMC Med Res Methodol
, vol.14
, pp. 135
-
-
Wan, X.1
Wang, W.2
Liu, J.3
Tong, T.4
-
26
-
-
84988397075
-
-
The Cochrane Collaboration, (accessed Feb 16,2016)
-
Higgins JPT, Green S Cochrane handbook for systematic reviews of interventions version 5.1.0 (updated March, 2011) 2011, The Cochrane Collaboration, (accessed Feb 16, 2016). http://handbook.cochrane.org.
-
(2011)
Cochrane handbook for systematic reviews of interventions version 5.1.0 (updated March, 2011)
-
-
Higgins, J.P.T.1
Green, S.2
-
27
-
-
0033198316
-
Random-effects meta-analyses are not always conservative
-
Poole C, Greenland S Random-effects meta-analyses are not always conservative. Am J Epidemiol 1999, 150:469-475.
-
(1999)
Am J Epidemiol
, vol.150
, pp. 469-475
-
-
Poole, C.1
Greenland, S.2
-
28
-
-
0033667604
-
Publication bias: a brief review for clinicians
-
Montori VM, Smieja M, Guyatt GH Publication bias: a brief review for clinicians. Mayo Clin Proc 2000, 75:1284-1288.
-
(2000)
Mayo Clin Proc
, vol.75
, pp. 1284-1288
-
-
Montori, V.M.1
Smieja, M.2
Guyatt, G.H.3
-
29
-
-
0030922816
-
Bias in meta-analysis detected by a simple, graphical test
-
Egger M, Davey Smith G, Schneider M, Minder C Bias in meta-analysis detected by a simple, graphical test. BMJ 1997, 315:629-634.
-
(1997)
BMJ
, vol.315
, pp. 629-634
-
-
Egger, M.1
Davey Smith, G.2
Schneider, M.3
Minder, C.4
-
30
-
-
84925548115
-
Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement
-
Moher D, Liberati A, Tetzlaff J, Altman DG Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. J Clin Epidemiol 2009, 62:1006-1012.
-
(2009)
J Clin Epidemiol
, vol.62
, pp. 1006-1012
-
-
Moher, D.1
Liberati, A.2
Tetzlaff, J.3
Altman, D.G.4
-
31
-
-
79955845135
-
Tadalafil monotherapy and as add-on to background bosentan in patients with pulmonary arterial hypertension
-
Barst RJ, Oudiz RJ, Beardsworth A, et al. Tadalafil monotherapy and as add-on to background bosentan in patients with pulmonary arterial hypertension. J Heart Lung Transplant 2011, 30:632-643.
-
(2011)
J Heart Lung Transplant
, vol.30
, pp. 632-643
-
-
Barst, R.J.1
Oudiz, R.J.2
Beardsworth, A.3
-
32
-
-
84938823530
-
Initial use of ambrisentan plus tadalafil in pulmonary arterial hypertension
-
Galiè N, Barberà JA, Frost AE, et al. Initial use of ambrisentan plus tadalafil in pulmonary arterial hypertension. N Engl J Med 2015, 373:834-844.
-
(2015)
N Engl J Med
, vol.373
, pp. 834-844
-
-
Galiè, N.1
Barberà, J.A.2
Frost, A.E.3
-
33
-
-
77952019637
-
Combination therapy with bosentan and sildenafil in Eisenmenger syndrome: a randomized, placebo-controlled, double-blinded trial
-
Iversen K, Jensen AS, Jensen TV, Vejlstrup NG, Søndergaard L Combination therapy with bosentan and sildenafil in Eisenmenger syndrome: a randomized, placebo-controlled, double-blinded trial. Eur Heart J 2010, 31:1124-1131.
-
(2010)
Eur Heart J
, vol.31
, pp. 1124-1131
-
-
Iversen, K.1
Jensen, A.S.2
Jensen, T.V.3
Vejlstrup, N.G.4
Søndergaard, L.5
-
34
-
-
84938903925
-
Bosentan added to sildenafil therapy in patients with pulmonary arterial hypertension
-
McLaughlin V, Channick RN, Ghofrani H-A, et al. Bosentan added to sildenafil therapy in patients with pulmonary arterial hypertension. Eur Respir J 2015, 46:405-413.
-
(2015)
Eur Respir J
, vol.46
, pp. 405-413
-
-
McLaughlin, V.1
Channick, R.N.2
Ghofrani, H.-A.3
-
35
-
-
84883108940
-
Macitentan and morbidity and mortality in pulmonary arterial hypertension
-
Pulido T, Adzerikho I, Channick RN, et al. Macitentan and morbidity and mortality in pulmonary arterial hypertension. N Engl J Med 2013, 369:809-818.
-
(2013)
N Engl J Med
, vol.369
, pp. 809-818
-
-
Pulido, T.1
Adzerikho, I.2
Channick, R.N.3
-
36
-
-
84951967550
-
Selexipag for the treatment of pulmonary arterial hypertension
-
Sitbon O, Channick RC, Chin KM, et al. Selexipag for the treatment of pulmonary arterial hypertension. N Engl J Med 2015, 373:2522-2533.
-
(2015)
N Engl J Med
, vol.373
, pp. 2522-2533
-
-
Sitbon, O.1
Channick, R.C.2
Chin, K.M.3
-
37
-
-
84880766215
-
Oral treprostinil for the treatment of pulmonary arterial hypertension in patients receiving background endothelin receptor antagonist and phosphodiesterase type 5 inhibitor therapy (the FREEDOM-C2 study): a randomized controlled trial
-
Tapson VF, Jing ZC, Xu KF, et al. Oral treprostinil for the treatment of pulmonary arterial hypertension in patients receiving background endothelin receptor antagonist and phosphodiesterase type 5 inhibitor therapy (the FREEDOM-C2 study): a randomized controlled trial. Chest 2013, 144:952-958.
-
(2013)
Chest
, vol.144
, pp. 952-958
-
-
Tapson, V.F.1
Jing, Z.C.2
Xu, K.F.3
-
38
-
-
84866515810
-
Oral treprostinil for the treatment of pulmonary arterial hypertension in patients on background endothelin receptor antagonist and/or phosphodiesterase type 5 inhibitor therapy (the FREEDOM-C study): a randomized controlled trial
-
Tapson VF, Torres F, Kermeen F, et al. Oral treprostinil for the treatment of pulmonary arterial hypertension in patients on background endothelin receptor antagonist and/or phosphodiesterase type 5 inhibitor therapy (the FREEDOM-C study): a randomized controlled trial. Chest 2012, 142:1383-1390.
-
(2012)
Chest
, vol.142
, pp. 1383-1390
-
-
Tapson, V.F.1
Torres, F.2
Kermeen, F.3
-
39
-
-
84902012561
-
Randomized study of adding tadalafil to existing ambrisentan in pulmonary arterial hypertension
-
Zhuang Y, Jiang B, Gao H, Zhao W Randomized study of adding tadalafil to existing ambrisentan in pulmonary arterial hypertension. Hypertens Res 2014, 37:507-512.
-
(2014)
Hypertens Res
, vol.37
, pp. 507-512
-
-
Zhuang, Y.1
Jiang, B.2
Gao, H.3
Zhao, W.4
-
40
-
-
45249119855
-
Treatment of patients with mildly symptomatic pulmonary arterial hypertension with bosentan (EARLY study): a double-blind, randomised controlled trial
-
Galiè N, Rubin L, Hoeper M, et al. Treatment of patients with mildly symptomatic pulmonary arterial hypertension with bosentan (EARLY study): a double-blind, randomised controlled trial. Lancet 2008, 371:2093-2100.
-
(2008)
Lancet
, vol.371
, pp. 2093-2100
-
-
Galiè, N.1
Rubin, L.2
Hoeper, M.3
-
41
-
-
84920263628
-
Effect of macitentan on hospitalizations: results from the SERAPHIN trial
-
Channick RN, Delcroix M, Ghofrani H-A, et al. Effect of macitentan on hospitalizations: results from the SERAPHIN trial. JACC Heart Fail 2015, 3:1-8.
-
(2015)
JACC Heart Fail
, vol.3
, pp. 1-8
-
-
Channick, R.N.1
Delcroix, M.2
Ghofrani, H.-A.3
-
42
-
-
84887343852
-
Efficacy of riociguat in pretreated versus treatment-naive patients with pulmonary arterial hypertension (PAH) in the phase III PATENT-1 study (ATS journals)
-
Humbert MJC, Galiè N, Hossein AG, et al. Efficacy of riociguat in pretreated versus treatment-naive patients with pulmonary arterial hypertension (PAH) in the phase III PATENT-1 study (ATS journals). Am J Respir Crit Care Med 2013, 187:A3534.
-
(2013)
Am J Respir Crit Care Med
, vol.187
, pp. A3534
-
-
Humbert, M.J.C.1
Galiè, N.2
Hossein, A.G.3
-
43
-
-
49149103553
-
Bosentan improves hemodynamics in patients receiving background sildenafil treatment: results from EARLY a randomized, double-blind, placebo controlled study in patients with mildly symptomatic pulmonary arterial hypertension
-
Rubin LJ, Simonneau G, Hoeper MM, Jansa P, Kusic-Pajic A, Galie N Bosentan improves hemodynamics in patients receiving background sildenafil treatment: results from EARLY a randomized, double-blind, placebo controlled study in patients with mildly symptomatic pulmonary arterial hypertension. Chest 2007, 132:487.
-
(2007)
Chest
, vol.132
, pp. 487
-
-
Rubin, L.J.1
Simonneau, G.2
Hoeper, M.M.3
Jansa, P.4
Kusic-Pajic, A.5
Galie, N.6
-
44
-
-
84887371563
-
Baseline characteristics and response to treatment in pretreated versus treatment-naïve patients with pulmonary arterial hypertension (PAH) in the phase III PATENT-1 study
-
Langleben D, Galie N, He J, et al. Baseline characteristics and response to treatment in pretreated versus treatment-naïve patients with pulmonary arterial hypertension (PAH) in the phase III PATENT-1 study. American Thoracic Society 2013, A3532.
-
(2013)
American Thoracic Society
, pp. A3532
-
-
Langleben, D.1
Galie, N.2
He, J.3
-
46
-
-
84887476582
-
Evaluation of the predictive value of a clinical worsening definition using 2-year outcomes in patients with pulmonary arterial hypertension: a REVEAL Registry analysis
-
Frost AE, Badesch DB, Miller DP, Benza RL, Meltzer LA, McGoon MD Evaluation of the predictive value of a clinical worsening definition using 2-year outcomes in patients with pulmonary arterial hypertension: a REVEAL Registry analysis. Chest 2013, 144:1521-1529.
-
(2013)
Chest
, vol.144
, pp. 1521-1529
-
-
Frost, A.E.1
Badesch, D.B.2
Miller, D.P.3
Benza, R.L.4
Meltzer, L.A.5
McGoon, M.D.6
-
47
-
-
84907190841
-
Effect of pulmonary arterial hypertension-specific therapies on health-related quality of life: a systematic review
-
Rival G, Lacasse Y, Martin S, Bonnet S, Provencher S Effect of pulmonary arterial hypertension-specific therapies on health-related quality of life: a systematic review. Chest 2014, 146:686-708.
-
(2014)
Chest
, vol.146
, pp. 686-708
-
-
Rival, G.1
Lacasse, Y.2
Martin, S.3
Bonnet, S.4
Provencher, S.5
-
48
-
-
77954759389
-
Predicting survival in pulmonary arterial hypertension: insights from the Registry to Evaluate Early and Long-Term Pulmonary Arterial Hypertension Disease Management (REVEAL)
-
Benza RL, Miller DP, Gomberg-Maitland M, et al. Predicting survival in pulmonary arterial hypertension: insights from the Registry to Evaluate Early and Long-Term Pulmonary Arterial Hypertension Disease Management (REVEAL). Circulation 2010, 122:164-172.
-
(2010)
Circulation
, vol.122
, pp. 164-172
-
-
Benza, R.L.1
Miller, D.P.2
Gomberg-Maitland, M.3
-
49
-
-
84925296872
-
Predicting outcomes in pulmonary arterial hypertension based on the 6-minute walk distance
-
Farber HW, Miller DP, McGoon MD, Frost AE, Benton WW, Benza RL Predicting outcomes in pulmonary arterial hypertension based on the 6-minute walk distance. J Heart Lung Transplant 2015, 34:362-368.
-
(2015)
J Heart Lung Transplant
, vol.34
, pp. 362-368
-
-
Farber, H.W.1
Miller, D.P.2
McGoon, M.D.3
Frost, A.E.4
Benton, W.W.5
Benza, R.L.6
|