-
1
-
-
34249043852
-
Zinc is a novel intracellular second messenger
-
Yamasaki, S. et al. Zinc is a novel intracellular second messenger. J. Cell Biol. 177, 637-645 (2007).
-
(2007)
J. Cell Biol
, vol.177
, pp. 637-645
-
-
Yamasaki, S.1
-
2
-
-
0028948696
-
Cloning and functional characterization of a mammalian zinc transporter that confers resistance to zinc
-
Palmiter, R. D., Findley, S. D. Cloning and functional characterization of a mammalian zinc transporter that confers resistance to zinc. EMBO J. 14, 639-649 (1995).
-
(1995)
EMBO J
, vol.14
, pp. 639-649
-
-
Palmiter, R.D.1
Findley, S.D.2
-
3
-
-
0029071561
-
Ion efflux systems involved in bacterial metal resistances
-
Nies, D. H., Silver, S. Ion efflux systems involved in bacterial metal resistances. J. Ind. Microbiol. 14, 186-199 (1995).
-
(1995)
J. Ind. Microbiol
, vol.14
, pp. 186-199
-
-
Nies, D.H.1
Silver, S.2
-
4
-
-
67650050211
-
Mammalian zinc transporters: Nutritional and physiologic regulation
-
Lichten, L. A., Cousins, R. J. Mammalian zinc transporters: nutritional and physiologic regulation. Annu. Rev. Nutr. 29, 153-176 (2009).
-
(2009)
Annu. Rev. Nutr
, vol.29
, pp. 153-176
-
-
Lichten, L.A.1
Cousins, R.J.2
-
5
-
-
84906261659
-
Current understanding of ZIP and ZnT zinc transporters in human health and diseases
-
Kambe, T., Hashimoto, A., Fujimoto, S. Current understanding of ZIP and ZnT zinc transporters in human health and diseases. Cell. Mol. Life Sci. 71, 3281-3295 (2014).
-
(2014)
Cell. Mol. Life Sci
, vol.71
, pp. 3281-3295
-
-
Kambe, T.1
Hashimoto, A.2
Fujimoto, S.3
-
6
-
-
0029911793
-
The yeast ZRT1 gene encodes the zinc transporter protein of a high-affinity uptake system induced by zinc limitation
-
Zhao, H., Eide, D. The yeast ZRT1 gene encodes the zinc transporter protein of a high-affinity uptake system induced by zinc limitation. Proc. Natl Acad. Sci. USA 93, 2454-2458 (1996).
-
(1996)
Proc. Natl Acad. Sci. USA
, vol.93
, pp. 2454-2458
-
-
Zhao, H.1
Eide, D.2
-
7
-
-
0032499739
-
Identification of a family of zinc transporter genes from Arabidopsis that respond to zinc deficiency
-
Grotz, N. et al. Identification of a family of zinc transporter genes from Arabidopsis that respond to zinc deficiency. Proc. Natl Acad. Sci. USA 95, 7220-7224 (1998).
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, pp. 7220-7224
-
-
Grotz, N.1
-
8
-
-
84875129764
-
The SLC39 family of zinc transporters
-
Jeong, J., Eide, D. J. The SLC39 family of zinc transporters. Mol. Aspects Med. 34, 612-619 (2013).
-
(2013)
Mol. Aspects Med
, vol.34
, pp. 612-619
-
-
Jeong, J.1
Eide, D.J.2
-
9
-
-
0041355296
-
The acrodermatitis enteropathica gene ZIP4 encodes a tissue-specific, zinc-regulated zinc transporter in mice
-
Dufner-Beattie, J. et al. The acrodermatitis enteropathica gene ZIP4 encodes a tissue-specific, zinc-regulated zinc transporter in mice. J. Biol. Chem. 278, 33474-33481 (2003).
-
(2003)
J. Biol. Chem
, vol.278
, pp. 33474-33481
-
-
Dufner-Beattie, J.1
-
10
-
-
59149094701
-
Regulation and function of Zip4, the acrodermatitis enteropathica gene
-
Andrews, G. K. Regulation and function of Zip4, the acrodermatitis enteropathica gene. Biochem. Soc. Trans. 36, 1242-1246 (2008).
-
(2008)
Biochem. Soc. Trans
, vol.36
, pp. 1242-1246
-
-
Andrews, G.K.1
-
11
-
-
0036648254
-
Identification of SLC39A4, a gene involved in acrodermatitis enteropathica
-
Kury, S. et al. Identification of SLC39A4, a gene involved in acrodermatitis enteropathica. Nat. Genet. 31, 239-240 (2002).
-
(2002)
Nat. Genet
, vol.31
, pp. 239-240
-
-
Kury, S.1
-
12
-
-
0036308552
-
A novel member of a zinc transporter family is defective in acrodermatitis enteropathica
-
Wang, K., Zhou, B., Kuo, Y. M., Zemansky, J., Gitschier, J. A novel member of a zinc transporter family is defective in acrodermatitis enteropathica. Am. J. Hum. Genet. 71, 66-73 (2002).
-
(2002)
Am. J. Hum. Genet
, vol.71
, pp. 66-73
-
-
Wang, K.1
Zhou, B.2
Kuo, Y.M.3
Zemansky, J.4
Gitschier, J.5
-
13
-
-
78049316349
-
Zip4 (Slc39a4) expression is activated in hepatocellular carcinomas and functions to repress apoptosis, enhance cell cycle and increase migration
-
Weaver, B. P. et al. Zip4 (Slc39a4) expression is activated in hepatocellular carcinomas and functions to repress apoptosis, enhance cell cycle and increase migration. PLoS One 5, e13158 (2010).
-
(2010)
PLoS One
, vol.5
, pp. e13158
-
-
Weaver, B.P.1
-
14
-
-
36749037264
-
Aberrant expression of zinc transporter ZIP4 (SLC39A4) significantly contributes to human pancreatic cancer pathogenesis and progression
-
Li, M. et al. Aberrant expression of zinc transporter ZIP4 (SLC39A4) significantly contributes to human pancreatic cancer pathogenesis and progression. Proc. Natl Acad. Sci. USA 104, 18636-18641 (2007).
-
(2007)
Proc. Natl Acad. Sci. USA
, vol.104
, pp. 18636-18641
-
-
Li, M.1
-
15
-
-
84880646695
-
ZIP4 is a novel molecular marker for glioma
-
Lin, Y. et al. ZIP4 is a novel molecular marker for glioma. Neuro Oncol 15, 1008-1016 (2013).
-
(2013)
Neuro Oncol
, vol.15
, pp. 1008-1016
-
-
Lin, Y.1
-
16
-
-
70349662179
-
Down-regulation of ZIP4 by RNA interference inhibits pancreatic cancer growth and increases the survival of nude mice with pancreatic cancer xenografts
-
Li, M. et al. Down-regulation of ZIP4 by RNA interference inhibits pancreatic cancer growth and increases the survival of nude mice with pancreatic cancer xenografts. Clin. Cancer Res. 15, 5993-6001 (2009).
-
(2009)
Clin. Cancer Res
, vol.15
, pp. 5993-6001
-
-
Li, M.1
-
17
-
-
77649162377
-
ZIP4 regulates pancreatic cancer cell growth by activating IL-6/STAT3 pathway through zinc finger transcription factor CREB
-
Zhang, Y. et al. ZIP4 regulates pancreatic cancer cell growth by activating IL-6/STAT3 pathway through zinc finger transcription factor CREB. Clin. Cancer Res. 16, 1423-1430 (2010).
-
(2010)
Clin. Cancer Res
, vol.16
, pp. 1423-1430
-
-
Zhang, Y.1
-
18
-
-
77953572927
-
ZIP4 upregulates the expression of neuropilin-1, vascular endothelial growth factor, and matrix metalloproteases in pancreatic cancer cell lines and xenografts
-
Zhang, Y., Chen, C., Yao, Q., Li, M. ZIP4 upregulates the expression of neuropilin-1, vascular endothelial growth factor, and matrix metalloproteases in pancreatic cancer cell lines and xenografts. Cancer Biol. Ther. 9, 236-242 (2010).
-
(2010)
Cancer Biol. Ther
, vol.9
, pp. 236-242
-
-
Zhang, Y.1
Chen, C.2
Yao, Q.3
Li, M.4
-
19
-
-
84878996202
-
Neurulation and neurite extension require the zinc transporter ZIP12 (slc39a12)
-
Chowanadisai, W., Graham, D. M., Keen, C. L., Rucker, R. B., Messerli, M. A. Neurulation and neurite extension require the zinc transporter ZIP12 (slc39a12). Proc. Natl Acad. Sci. USA 110, 9903-9908 (2013).
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
, pp. 9903-9908
-
-
Chowanadisai, W.1
Graham, D.M.2
Keen, C.L.3
Rucker, R.B.4
Messerli, M.A.5
-
20
-
-
44649187851
-
Spondylocheiro dysplastic form of the Ehlers-Danlos syndrome-an autosomal-recessive entity caused by mutations in the zinc transporter gene SLC39A13
-
Giunta, C. et al. Spondylocheiro dysplastic form of the Ehlers-Danlos syndrome-an autosomal-recessive entity caused by mutations in the zinc transporter gene SLC39A13. Am. J. Hum. Genet. 82, 1290-1305 (2008).
-
(2008)
Am. J. Hum. Genet
, vol.82
, pp. 1290-1305
-
-
Giunta, C.1
-
21
-
-
56649111126
-
The zinc transporter SLC39A13/ZIP13 is required for connective tissue development; Its involvement in BMP/TGF-beta signaling pathways
-
Fukada, T. et al. The zinc transporter SLC39A13/ZIP13 is required for connective tissue development; its involvement in BMP/TGF-beta signaling pathways. PLoS One 3, e3642 (2008).
-
(2008)
PLoS One
, vol.3
, pp. e3642
-
-
Fukada, T.1
-
22
-
-
84871396523
-
Promotion of vesicular zinc efflux by ZIP13 and its implications for spondylocheiro dysplastic Ehlers-Danlos syndrome
-
Jeong, J. et al. Promotion of vesicular zinc efflux by ZIP13 and its implications for spondylocheiro dysplastic Ehlers-Danlos syndrome. Proc. Natl Acad. Sci. USA 109, E3530-E3538 (2012).
-
(2012)
Proc. Natl Acad. Sci. USA
, vol.109
, pp. E3530-E3538
-
-
Jeong, J.1
-
23
-
-
84874232263
-
ZIP8 regulates host defense through zinc-mediated inhibition of NF-kappaB
-
Liu, M. J. et al. ZIP8 regulates host defense through zinc-mediated inhibition of NF-kappaB. Cell Rep. 3, 386-400 (2013).
-
(2013)
Cell Rep
, vol.3
, pp. 386-400
-
-
Liu, M.J.1
-
24
-
-
84894114401
-
Regulation of the catabolic cascade in osteoarthritis by the zinc-ZIP8-MTF1 axis
-
Kim, J. H. et al. Regulation of the catabolic cascade in osteoarthritis by the zinc-ZIP8-MTF1 axis. Cell 156, 730-743 (2014).
-
(2014)
Cell
, vol.156
, pp. 730-743
-
-
Kim, J.H.1
-
25
-
-
40049108006
-
Zip6 (LIV-1) regulates zinc uptake in neuroblastoma cells under resting but not depolarizing conditions
-
Chowanadisai, W., Lonnerdal, B., Kelleher, S. L. Zip6 (LIV-1) regulates zinc uptake in neuroblastoma cells under resting but not depolarizing conditions. Brain Res. 1199, 10-19 (2008).
-
(2008)
Brain Res
, vol.1199
, pp. 10-19
-
-
Chowanadisai, W.1
Lonnerdal, B.2
Kelleher, S.L.3
-
26
-
-
70449389246
-
LIV-1 enhances the aggressive phenotype through the induction of epithelial to mesenchymal transition in human pancreatic carcinoma cells
-
Unno, J. et al. LIV-1 enhances the aggressive phenotype through the induction of epithelial to mesenchymal transition in human pancreatic carcinoma cells. Int. J. Oncol. 35, 813-821 (2009).
-
(2009)
Int. J. Oncol
, vol.35
, pp. 813-821
-
-
Unno, J.1
-
27
-
-
81155137295
-
LIV-1 promotes prostate cancer epithelial-to-mesenchymal transition and metastasis through HB-EGF shedding and EGFR-mediated ERK signaling
-
Lue, H. W. et al. LIV-1 promotes prostate cancer epithelial-to-mesenchymal transition and metastasis through HB-EGF shedding and EGFR-mediated ERK signaling. PLoS One 6, e27720 (2011).
-
(2011)
PLoS One
, vol.6
, pp. e27720
-
-
Lue, H.W.1
-
28
-
-
84864341746
-
Zinc and Cancer: Implications for LIV-1 in breast cancer
-
Grattan, B. J., Freake, H. C. Zinc and cancer: implications for LIV-1 in breast cancer. Nutrients 4, 648-675 (2012).
-
(2012)
Nutrients
, vol.4
, pp. 648-675
-
-
Grattan, B.J.1
Freake, H.C.2
-
29
-
-
66349089042
-
An update on mutations of the SLC39A4 gene in acrodermatitis enteropathica
-
Schmitt, S. et al. An update on mutations of the SLC39A4 gene in acrodermatitis enteropathica. Hum. Mutat. 30, 926-933 (2009).
-
(2009)
Hum. Mutat
, vol.30
, pp. 926-933
-
-
Schmitt, S.1
-
30
-
-
84857194199
-
Clinical utility gene card for: Acrodermatitis enteropathica
-
Kury, S., Kharfi, M., Schmitt, S., Bezieau, S. Clinical utility gene card for: acrodermatitis enteropathica. Eur. J. Hum. Genet. 20, 297-304 (2012).
-
(2012)
Eur. J. Hum. Genet
, vol.20
, pp. 297-304
-
-
Kury, S.1
Kharfi, M.2
Schmitt, S.3
Bezieau, S.4
-
31
-
-
2642587498
-
Zinc-stimulated endocytosis controls activity of the mouse ZIP1 and ZIP3 zinc uptake transporters
-
Wang, F. et al. Zinc-stimulated endocytosis controls activity of the mouse ZIP1 and ZIP3 zinc uptake transporters. J. Biol. Chem. 279, 24631-24639 (2004).
-
(2004)
J. Biol. Chem
, vol.279
, pp. 24631-24639
-
-
Wang, F.1
-
32
-
-
58149460415
-
Novel proteolytic processing of the ectodomain of the zinc transporter ZIP4 (SLC39A4) during zinc deficiency is inhibited by acrodermatitis enteropathica mutations
-
Kambe, T., Andrews, G. K. Novel proteolytic processing of the ectodomain of the zinc transporter ZIP4 (SLC39A4) during zinc deficiency is inhibited by acrodermatitis enteropathica mutations. Mol. Cell Biol. 29, 129-139 (2009).
-
(2009)
Mol. Cell Biol
, vol.29
, pp. 129-139
-
-
Kambe, T.1
Andrews, G.K.2
-
33
-
-
34548232365
-
Inference of macromolecular assemblies from crystalline state
-
Krissinel, E., Henrick, K. Inference of macromolecular assemblies from crystalline state. J. Mol. Biol. 372, 774-797 (2007).
-
(2007)
J. Mol. Biol
, vol.372
, pp. 774-797
-
-
Krissinel, E.1
Henrick, K.2
-
34
-
-
77954288774
-
Dali server: Conservation mapping in 3D
-
Holm, L., Rosenstrom, P. Dali server: conservation mapping in 3D. Nucleic Acids Res. 38, W545-W549 (2010).
-
(2010)
Nucleic Acids Res
, vol.38
, pp. W545-W549
-
-
Holm, L.1
Rosenstrom, P.2
-
35
-
-
55249098911
-
Another role of proline: Stabilization interactions in proteins and protein complexes concerning proline and tryptophane
-
Biedermannova, L., E Riley, K., Berka, K., Hobza, P., Vondrasek, J. Another role of proline: stabilization interactions in proteins and protein complexes concerning proline and tryptophane. Phys. Chem. Chem. Phys. 10, 6350-6359 (2008).
-
(2008)
Phys. Chem. Chem. Phys
, vol.10
, pp. 6350-6359
-
-
Biedermannova, L.E.1
Riley, K.2
Berka, K.3
Hobza, P.4
Vondrasek, J.5
-
36
-
-
1542376716
-
Acrodermatitis enteropathica mutations affect transport activity, localization and zinc-responsive trafficking of the mouse ZIP4 zinc transporter
-
Wang, F. et al. Acrodermatitis enteropathica mutations affect transport activity, localization and zinc-responsive trafficking of the mouse ZIP4 zinc transporter. Hum. Mol. Genet. 13, 563-571 (2004).
-
(2004)
Hum. Mol. Genet
, vol.13
, pp. 563-571
-
-
Wang, F.1
-
37
-
-
0034710975
-
Altered selectivity in an Arabidopsis metal transporter
-
Rogers, E. E., Eide, D. J., Guerinot, M. L. Altered selectivity in an Arabidopsis metal transporter. Proc. Natl Acad. Sci. USA 97, 12356-12360 (2000).
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 12356-12360
-
-
Rogers, E.E.1
Eide, D.J.2
Guerinot, M.L.3
-
38
-
-
84897505370
-
Molecular mechanism of Mg2\+-dependent gating in CorA
-
Dalmas, O., Sompornpisut, P., Bezanilla, F., Perozo, E. Molecular mechanism of Mg2\+-dependent gating in CorA. Nat. Commun. 5, 3590 (2014).
-
(2014)
Nat. Commun
, vol.5
, pp. 3590
-
-
Dalmas, O.1
Sompornpisut, P.2
Bezanilla, F.3
Perozo, E.4
-
39
-
-
34648833810
-
Structure of the zinc transporter YiiP
-
Lu, M., Fu, D. Structure of the zinc transporter YiiP. Science 317, 1746-1748 (2007).
-
(2007)
Science
, vol.317
, pp. 1746-1748
-
-
Lu, M.1
Fu, D.2
-
40
-
-
70349789244
-
Structural basis for autoregulation of the zinc transporter YiiP
-
Lu, M., Chai, J., Fu, D. Structural basis for autoregulation of the zinc transporter YiiP. Nat. Struct. Mol. Biol. 16, 1063-1067 (2009).
-
(2009)
Nat. Struct. Mol. Biol
, vol.16
, pp. 1063-1067
-
-
Lu, M.1
Chai, J.2
Fu, D.3
-
41
-
-
34548324652
-
Crystal structure of the MgtE Mg2\+ transporter
-
Hattori, M., Tanaka, Y., Fukai, S., Ishitani, R., Nureki, O. Crystal structure of the MgtE Mg2\+ transporter. Nature 448, 1072-1075 (2007).
-
(2007)
Nature
, vol.448
, pp. 1072-1075
-
-
Hattori, M.1
Tanaka, Y.2
Fukai, S.3
Ishitani, R.4
Nureki, O.5
-
42
-
-
70450222720
-
Mg(2\+)-dependent gating of bacterial MgtE channel underlies Mg 2\+) homeostasis
-
Hattori, M. et al. Mg(2\+)-dependent gating of bacterial MgtE channel underlies Mg(2\+) homeostasis. EMBO J. 28, 3602-3612 (2009).
-
(2009)
EMBO J
, vol.28
, pp. 3602-3612
-
-
Hattori, M.1
-
43
-
-
78649863705
-
Selective electrodiffusion of zinc ions in a Zrt-, Irt-like protein ZIPB
-
Lin, W., Chai, J., Love, J., Fu, D. Selective electrodiffusion of zinc ions in a Zrt-, Irt-like protein, ZIPB. J. Biol. Chem. 285, 39013-39020 (2010).
-
(2010)
J. Biol. Chem
, vol.285
, pp. 39013-39020
-
-
Lin, W.1
Chai, J.2
Love, J.3
Fu, D.4
-
44
-
-
84890285607
-
Mechanism of transport modulation by an extracellular loop in an archaeal excitatory amino acid transporter (EAAT) homolog
-
Mulligan, C., Mindell, J. A. Mechanism of transport modulation by an extracellular loop in an archaeal excitatory amino acid transporter (EAAT) homolog. J. Biol. Chem. 288, 35266-35276 (2013).
-
(2013)
J. Biol. Chem
, vol.288
, pp. 35266-35276
-
-
Mulligan, C.1
Mindell, J.A.2
-
45
-
-
70349669073
-
Evolutionary descent of prion genes from the ZIP family of metal ion transporters
-
Schmitt-Ulms, G., Ehsani, S., Watts, J. C., Westaway, D., Wille, H. Evolutionary descent of prion genes from the ZIP family of metal ion transporters. PLoS One 4, e7208 (2009).
-
(2009)
PLoS One
, vol.4
, pp. e7208
-
-
Schmitt-Ulms, G.1
Ehsani, S.2
Watts, J.C.3
Westaway, D.4
Wille, H.5
-
46
-
-
84883611845
-
The ZIP5 ectodomain co-localizes with PrP and may acquire a PrP-like fold that assembles into a dimer
-
Pocanschi, C. L. et al. The ZIP5 ectodomain co-localizes with PrP and may acquire a PrP-like fold that assembles into a dimer. PLoS One 8, e72446 (2013).
-
(2013)
PLoS One
, vol.8
, pp. e72446
-
-
Pocanschi, C.L.1
-
47
-
-
84937459728
-
Computation and functional studies provide a model for the structure of the zinc transporter hZIP4
-
Antala, S., Ovchinnikov, S., Kamisetty, H., Baker, D., Dempski, R. E. Computation and functional studies provide a model for the structure of the zinc transporter hZIP4. J. Biol. Chem. 290, 17796-17805 (2015).
-
(2015)
J. Biol. Chem
, vol.290
, pp. 17796-17805
-
-
Antala, S.1
Ovchinnikov, S.2
Kamisetty, H.3
Baker, D.4
Dempski, R.E.5
-
48
-
-
81155123666
-
Biochemical characterization of human ZIP13 protein: A homodimerized zinc transporter involved in the spondylocheiro dysplastic Ehlers-Danlos syndrome
-
Bin, B. H. et al. Biochemical characterization of human ZIP13 protein: a homodimerized zinc transporter involved in the spondylocheiro dysplastic Ehlers-Danlos syndrome. J. Biol. Chem. 286, 40255-40265 (2011).
-
(2011)
J. Biol. Chem
, vol.286
, pp. 40255-40265
-
-
Bin, B.H.1
-
49
-
-
1042301402
-
Zn2\+-stimulated endocytosis of the mZIP4 zinc transporter regulates its location at the plasma membrane
-
Kim, B. E. et al. Zn2\+-stimulated endocytosis of the mZIP4 zinc transporter regulates its location at the plasma membrane. J. Biol. Chem. 279, 4523-4530 (2004).
-
(2004)
J. Biol. Chem
, vol.279
, pp. 4523-4530
-
-
Kim, B.E.1
-
50
-
-
0031059866
-
Processing of X-ray diffraction data collected in oscillation mode
-
Otwinowski, Z., Minor, W. Processing of X-ray diffraction data collected in oscillation mode. Macromol. Crystallogr. Part A 276, 307-326 (1997).
-
(1997)
Macromol. Crystallogr. Part A
, vol.276
, pp. 307-326
-
-
Otwinowski, Z.1
Minor, W.2
-
51
-
-
76449098262
-
PHENIX: A comprehensive Python-based system for macromolecular structure solution
-
Adams, P. D. et al. PHENIX: a comprehensive Python-based system for macromolecular structure solution. Acta Crystallogr. D Biol. Crystallogr. 66, 213-221 (2010).
-
(2010)
Acta Crystallogr. D Biol. Crystallogr
, vol.66
, pp. 213-221
-
-
Adams, P.D.1
-
52
-
-
77949535720
-
Features and development of Coot
-
Emsley, P., Lohkamp, B., Scott, W. G., Cowtan, K. Features and development of Coot. Acta Crystallogr. D Biol. Crystallogr. 66, 486-501 (2010).
-
(2010)
Acta Crystallogr. D Biol. Crystallogr
, vol.66
, pp. 486-501
-
-
Emsley, P.1
Lohkamp, B.2
Scott, W.G.3
Cowtan, K.4
-
53
-
-
79953737180
-
Overview of the CCP4 suite and current developments
-
Winn, M. D. et al. Overview of the CCP4 suite and current developments. Acta Crystallogr. D Biol. Crystallogr. 67, 235-242 (2011).
-
(2011)
Acta Crystallogr. D Biol. Crystallogr
, vol.67
, pp. 235-242
-
-
Winn, M.D.1
|