NSs virulence factor of Rift Valley fever virus engages the F-box proteins FBXW11 and β-TRCP1 to degrade the antiviral protein kinase PKR

Journal of Virology

Volumn 90, Issue 13, 2016, Pages 6140-6147

  Kainulainen, Markus ^a   Lau, Simone ^a,b   Samuel, Charles E ^c   Hornung, Veit ^d,e   Weber, Friedemann ^a,b  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

^b JUSTUS LIEBIG UNIVERSITY   (Germany)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY HOSPITAL BONN   (Germany)

^e UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BETA TRANSDUCIN REPEAT CONTAINING PROTEIN; F BOX PROTEIN; FBXW11 PROTEIN; INITIATION FACTOR 2ALPHA; PROTEIN KINASE R; SKP1 PROTEIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; VIRULENCE FACTOR; CULLIN; CULLIN 1; FBXW11 PROTEIN, HUMAN; S PHASE KINASE ASSOCIATED PROTEIN; SKP1 PROTEIN, HUMAN; SMALL INTERFERING RNA; UBIQUITIN PROTEIN LIGASE; VIRAL PROTEIN;

ARTICLE; AUTOPHOSPHORYLATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN SYNTHESIS; RIFT VALLEY FEVER VIRUS; UBIQUITINATION; VIRUS REPLICATION; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL LINE; CHEMISTRY; CHLOROCEBUS AETHIOPS; DEFICIENCY; GENETICS; METABOLISM; PATHOGENICITY; VERO CELL LINE;

ANIMALS; BETA-TRANSDUCIN REPEAT-CONTAINING PROTEINS; CELL LINE; CERCOPITHECUS AETHIOPS; CULLIN PROTEINS; EIF-2 KINASE; F-BOX PROTEINS; HUMANS; RIFT VALLEY FEVER VIRUS; RNA, SMALL INTERFERING; S-PHASE KINASE-ASSOCIATED PROTEINS; UBIQUITIN-PROTEIN LIGASES; VERO CELLS; VIRAL NONSTRUCTURAL PROTEINS; VIRULENCE FACTORS; VIRUS REPLICATION;

EID: 84975298037     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00016-16     Document Type: Article

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