메뉴 건너뛰기




Volumn 23, Issue 7, 2016, Pages 496-505

Achieving sustained virologic response after interferon-free hepatitis C virus treatment correlates with hepatic interferon gene expression changes independent of cirrhosis

Author keywords

cirrhosis; endogenous interferons; hepatitis C virus; interferon free therapy; treatment relapse

Indexed keywords

INTERFERON; LEDIPASVIR PLUS SOFOSBUVIR; MESSENGER RNA; MICRORNA; MICRORNA 101; MICRORNA 122; MICRORNA 130A; MICRORNA 141; MICRORNA 155; MICRORNA 192; MICRORNA 196; MICRORNA 199A; MICRORNA 208B; MICRORNA 21; MICRORNA 27A; MICRORNA 29; MICRORNA 296; MICRORNA 351; MICRORNA 431; MICRORNA 448; MICRORNA 499; MICRORNA 508; MICRORNA 99A; MICRORNA LET 7A; MICRORNA LET 7B; MICRORNA LET 7C; MICRORNA LET 7F; RADALBUVIR; UNCLASSIFIED DRUG; UNINDEXED DRUG; VEDROPREVIR;

EID: 84975152240     PISSN: 13520504     EISSN: 13652893     Source Type: Journal    
DOI: 10.1111/jvh.12510     Document Type: Article
Times cited : (37)

References (50)
  • 1
    • 84937975305 scopus 로고    scopus 로고
    • Sorting out cirrhosis: mechanisms of non-response to hepatitis C therapy
    • Al Marzooqi SH, Feld JJ. Sorting out cirrhosis: mechanisms of non-response to hepatitis C therapy. Liver Int 2015; 35(8): 1923–1933.
    • (2015) Liver Int , vol.35 , Issue.8 , pp. 1923-1933
    • Al Marzooqi, S.H.1    Feld, J.J.2
  • 2
    • 79959381354 scopus 로고    scopus 로고
    • Telaprevir for retreatment of HCV infection
    • Zeuzem S, Andreone P, Pol S et al. Telaprevir for retreatment of HCV infection. N Engl J Med 2011; 364(25): 2417–2428.
    • (2011) N Engl J Med , vol.364 , Issue.25 , pp. 2417-2428
    • Zeuzem, S.1    Andreone, P.2    Pol, S.3
  • 3
    • 79953176289 scopus 로고    scopus 로고
    • Boceprevir for previously treated chronic HCV genotype 1 infection
    • Bacon BR, Gordon SC, Lawitz E et al. Boceprevir for previously treated chronic HCV genotype 1 infection. N Engl J Med 2011; 364(13): 1207–1217.
    • (2011) N Engl J Med , vol.364 , Issue.13 , pp. 1207-1217
    • Bacon, B.R.1    Gordon, S.C.2    Lawitz, E.3
  • 4
    • 80052826527 scopus 로고    scopus 로고
    • Response-guided telaprevir combination treatment for hepatitis C virus infection
    • Sherman KE, Flamm SL, Afdhal NH et al. Response-guided telaprevir combination treatment for hepatitis C virus infection. N Engl J Med 2011; 365(11): 1014–1024.
    • (2011) N Engl J Med , vol.365 , Issue.11 , pp. 1014-1024
    • Sherman, K.E.1    Flamm, S.L.2    Afdhal, N.H.3
  • 5
    • 79953173221 scopus 로고    scopus 로고
    • Boceprevir for untreated chronic HCV genotype 1 infection
    • Poordad F, McCone J Jr, Bacon BR et al. Boceprevir for untreated chronic HCV genotype 1 infection. N Engl J Med 2011; 364(13): 1195–1206.
    • (2011) N Engl J Med , vol.364 , Issue.13 , pp. 1195-1206
    • Poordad, F.1    McCone, J.2    Bacon, B.R.3
  • 6
    • 84883089005 scopus 로고    scopus 로고
    • Sofosbuvir and ribavirin for hepatitis C genotype 1 in patients with unfavorable treatment characteristics: a randomized clinical trial
    • Osinusi A, Meissner EG, Lee YJ et al. Sofosbuvir and ribavirin for hepatitis C genotype 1 in patients with unfavorable treatment characteristics: a randomized clinical trial. JAMA 2013; 310(8): 804–811.
    • (2013) JAMA , vol.310 , Issue.8 , pp. 804-811
    • Osinusi, A.1    Meissner, E.G.2    Lee, Y.J.3
  • 7
    • 84900992889 scopus 로고    scopus 로고
    • Sofosbuvir and ribavirin in HCV genotypes 2 and 3
    • Zeuzem S, Dusheiko GM, Salupere R et al. Sofosbuvir and ribavirin in HCV genotypes 2 and 3. N Engl J Med 2014; 370(21): 1993–2001.
    • (2014) N Engl J Med , vol.370 , Issue.21 , pp. 1993-2001
    • Zeuzem, S.1    Dusheiko, G.M.2    Salupere, R.3
  • 8
    • 84877739274 scopus 로고    scopus 로고
    • Sofosbuvir for hepatitis C genotype 2 or 3 in patients without treatment options
    • Jacobson IM, Gordon SC, Kowdley KV et al. Sofosbuvir for hepatitis C genotype 2 or 3 in patients without treatment options. N Engl J Med 2013; 368(20): 1867–1877.
    • (2013) N Engl J Med , vol.368 , Issue.20 , pp. 1867-1877
    • Jacobson, I.M.1    Gordon, S.C.2    Kowdley, K.V.3
  • 9
    • 84894297488 scopus 로고    scopus 로고
    • Efficacy of nucleotide polymerase inhibitor sofosbuvir plus the NS5A inhibitor ledipasvir or the NS5B non-nucleoside inhibitor GS-9669 against HCV genotype 1 infection
    • Gane EJ, Stedman CA, Hyland RH et al. Efficacy of nucleotide polymerase inhibitor sofosbuvir plus the NS5A inhibitor ledipasvir or the NS5B non-nucleoside inhibitor GS-9669 against HCV genotype 1 infection. Gastroenterology 2014; 146(3): 736–743.
    • (2014) Gastroenterology , vol.146 , Issue.3 , pp. 736-743
    • Gane, E.J.1    Stedman, C.A.2    Hyland, R.H.3
  • 10
    • 84898669547 scopus 로고    scopus 로고
    • Ledipasvir and sofosbuvir for previously treated HCV genotype 1 infection
    • Afdhal N, Reddy KR, Nelson DR et al. Ledipasvir and sofosbuvir for previously treated HCV genotype 1 infection. N Engl J Med 2014; 370(16): 1483–1493.
    • (2014) N Engl J Med , vol.370 , Issue.16 , pp. 1483-1493
    • Afdhal, N.1    Reddy, K.R.2    Nelson, D.R.3
  • 11
    • 84901036125 scopus 로고    scopus 로고
    • ABT-450/r-ombitasvir and dasabuvir with ribavirin for hepatitis C with cirrhosis
    • Poordad F, Hezode C, Trinh R et al. ABT-450/r-ombitasvir and dasabuvir with ribavirin for hepatitis C with cirrhosis. N Engl J Med 2014; 370(21): 1973–1982.
    • (2014) N Engl J Med , vol.370 , Issue.21 , pp. 1973-1982
    • Poordad, F.1    Hezode, C.2    Trinh, R.3
  • 12
    • 84905492815 scopus 로고    scopus 로고
    • Endogenous intrahepatic IFNs and association with IFN-free HCV treatment outcome
    • Meissner EG, Wu D, Osinusi A et al. Endogenous intrahepatic IFNs and association with IFN-free HCV treatment outcome. J Clin Invest 2014; 124(8): 3352–3363.
    • (2014) J Clin Invest , vol.124 , Issue.8 , pp. 3352-3363
    • Meissner, E.G.1    Wu, D.2    Osinusi, A.3
  • 13
    • 84893430467 scopus 로고    scopus 로고
    • Interferon-lambda4 (IFNL4) transcript expression in human liver tissue samples
    • Amanzada A, Kopp W, Spengler U, Ramadori G, Mihm S. Interferon-lambda4 (IFNL4) transcript expression in human liver tissue samples. PLoS One 2013; 8(12): e84026.
    • (2013) PLoS One , vol.8 , Issue.12
    • Amanzada, A.1    Kopp, W.2    Spengler, U.3    Ramadori, G.4    Mihm, S.5
  • 14
    • 84906302905 scopus 로고    scopus 로고
    • Restoration of HCV-specific CD8+ T cell function by interferon-free therapy
    • Martin B, Hennecke N, Lohmann V et al. Restoration of HCV-specific CD8+ T cell function by interferon-free therapy. J Hepatol 2014; 61(3): 538–543.
    • (2014) J Hepatol , vol.61 , Issue.3 , pp. 538-543
    • Martin, B.1    Hennecke, N.2    Lohmann, V.3
  • 15
    • 84907487818 scopus 로고    scopus 로고
    • Impaired expression of type I and type II interferon receptors in HCV-associated chronic liver disease and liver cirrhosis
    • Chandra PK, Gunduz F, Hazari S et al. Impaired expression of type I and type II interferon receptors in HCV-associated chronic liver disease and liver cirrhosis. PLoS One 2014; 9(9): e108616.
    • (2014) PLoS One , vol.9 , Issue.9
    • Chandra, P.K.1    Gunduz, F.2    Hazari, S.3
  • 16
    • 84925428093 scopus 로고    scopus 로고
    • Ombitasvir, paritaprevir co-dosed with ritonavir, dasabuvir, and ribavirin for hepatitis C in patients co-infected with HIV-1: a randomized trial
    • Sulkowski MS, Eron JJ, Wyles D et al. Ombitasvir, paritaprevir co-dosed with ritonavir, dasabuvir, and ribavirin for hepatitis C in patients co-infected with HIV-1: a randomized trial. JAMA 2015; 313(12): 1223–1231.
    • (2015) JAMA , vol.313 , Issue.12 , pp. 1223-1231
    • Sulkowski, M.S.1    Eron, J.J.2    Wyles, D.3
  • 17
    • 84962093570 scopus 로고    scopus 로고
    • Ribavirin restores IFNalpha responsiveness in HCV-infected livers by epigenetic remodelling at interferon stimulated genes
    • epub ahead of print
    • Testoni B, Durantel D, Lebosse F et al. Ribavirin restores IFNalpha responsiveness in HCV-infected livers by epigenetic remodelling at interferon stimulated genes. Gut 2015; epub ahead of print.
    • (2015) Gut
    • Testoni, B.1    Durantel, D.2    Lebosse, F.3
  • 18
    • 84927798710 scopus 로고    scopus 로고
    • The multifaceted functions of ribavirin: antiviral, immunomodulator, or both?
    • Mondelli MU. The multifaceted functions of ribavirin: antiviral, immunomodulator, or both? Hepatology 2014; 60(4): 1126–1129.
    • (2014) Hepatology , vol.60 , Issue.4 , pp. 1126-1129
    • Mondelli, M.U.1
  • 19
    • 77953893773 scopus 로고    scopus 로고
    • Ribavirin improves early responses to peginterferon through improved interferon signaling
    • Feld JJ, Lutchman GA, Heller T et al. Ribavirin improves early responses to peginterferon through improved interferon signaling. Gastroenterology 2010; 139(1): 154–62 e4.
    • (2010) Gastroenterology , vol.139 , Issue.1 , pp. 154-162
    • Feld, J.J.1    Lutchman, G.A.2    Heller, T.3
  • 20
    • 84927783630 scopus 로고    scopus 로고
    • Ribavirin improves the IFN-γ response of natural killer cells to IFN-based therapy of hepatitis C virus infection
    • Werner JM, Serti E, Chepa-Lotrea X et al. Ribavirin improves the IFN-γ response of natural killer cells to IFN-based therapy of hepatitis C virus infection. Hepatology 2014; 60(4): 1160–1169.
    • (2014) Hepatology , vol.60 , Issue.4 , pp. 1160-1169
    • Werner, J.M.1    Serti, E.2    Chepa-Lotrea, X.3
  • 21
    • 84925607745 scopus 로고    scopus 로고
    • Virological response after 6 week triple-drug regimens for hepatitis C: a proof-of-concept phase 2A cohort study
    • Kohli A, Osinusi A, Sims Z et al. Virological response after 6 week triple-drug regimens for hepatitis C: a proof-of-concept phase 2A cohort study. Lancet 2015; 385(9973): 1107–1113.
    • (2015) Lancet , vol.385 , Issue.9973 , pp. 1107-1113
    • Kohli, A.1    Osinusi, A.2    Sims, Z.3
  • 22
    • 0029039362 scopus 로고
    • Histological grading and staging of chronic hepatitis
    • Ishak K, Baptista A, Bianchi L et al. Histological grading and staging of chronic hepatitis. J Hepatol 1995; 22(6): 696–699.
    • (1995) J Hepatol , vol.22 , Issue.6 , pp. 696-699
    • Ishak, K.1    Baptista, A.2    Bianchi, L.3
  • 23
    • 21144443961 scopus 로고    scopus 로고
    • Longitudinal analysis of the group A Streptococcus transcriptome in experimental pharyngitis in cynomolgus macaques
    • Virtaneva K, Porcella SF, Graham MR et al. Longitudinal analysis of the group A Streptococcus transcriptome in experimental pharyngitis in cynomolgus macaques. Proc Natl Acad Sci USA 2005; 102(25): 9014–9019.
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.25 , pp. 9014-9019
    • Virtaneva, K.1    Porcella, S.F.2    Graham, M.R.3
  • 24
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: a practical and powerful approach to multiple testing
    • Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc Ser B Methodol 1995; 57: 289–300.
    • (1995) J R Stat Soc Ser B Methodol , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 25
    • 84873083416 scopus 로고    scopus 로고
    • A variant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of hepatitis C virus
    • Prokunina-Olsson L, Muchmore B, Tang W et al. A variant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of hepatitis C virus. Nat Genet 2013; 45(2): 164–171.
    • (2013) Nat Genet , vol.45 , Issue.2 , pp. 164-171
    • Prokunina-Olsson, L.1    Muchmore, B.2    Tang, W.3
  • 26
    • 84889675731 scopus 로고    scopus 로고
    • Mechanism of action of ribavirin in anti-HCV regimens: new insights for an age-old question?
    • Testoni B, Levrero M, Durantel D. Mechanism of action of ribavirin in anti-HCV regimens: new insights for an age-old question? Gut 2014; 63(1): 3–4.
    • (2014) Gut , vol.63 , Issue.1 , pp. 3-4
    • Testoni, B.1    Levrero, M.2    Durantel, D.3
  • 27
    • 81155131454 scopus 로고    scopus 로고
    • Ribavirin enhances IFN-alpha signalling and MxA expression: a novel immune modulation mechanism during treatment of HCV
    • Stevenson NJ, Murphy AG, Bourke NM, Keogh CA, Hegarty JE, O'Farrelly C. Ribavirin enhances IFN-alpha signalling and MxA expression: a novel immune modulation mechanism during treatment of HCV. PLoS One 2011; 6(11): e27866.
    • (2011) PLoS One , vol.6 , Issue.11
    • Stevenson, N.J.1    Murphy, A.G.2    Bourke, N.M.3    Keogh, C.A.4    Hegarty, J.E.5    O'Farrelly, C.6
  • 28
    • 84882737964 scopus 로고    scopus 로고
    • microRNA control of interferons and interferon induced anti-viral activity
    • Sedger LM. microRNA control of interferons and interferon induced anti-viral activity. Mol Immunol 2013; 56(4): 781–793.
    • (2013) Mol Immunol , vol.56 , Issue.4 , pp. 781-793
    • Sedger, L.M.1
  • 29
    • 77952572587 scopus 로고    scopus 로고
    • New perspectives in MicroRNA regulation of innate immunity
    • Gantier MP. New perspectives in MicroRNA regulation of innate immunity. J Interferon Cytokine Res 2010; 30(5): 283–289.
    • (2010) J Interferon Cytokine Res , vol.30 , Issue.5 , pp. 283-289
    • Gantier, M.P.1
  • 30
    • 79751484450 scopus 로고    scopus 로고
    • Identification of miRNomes in human liver and hepatocellular carcinoma reveals miR-199a/b-3p as therapeutic target for hepatocellular carcinoma
    • Hou J, Lin L, Zhou W et al. Identification of miRNomes in human liver and hepatocellular carcinoma reveals miR-199a/b-3p as therapeutic target for hepatocellular carcinoma. Cancer Cell 2011; 19(2): 232–243.
    • (2011) Cancer Cell , vol.19 , Issue.2 , pp. 232-243
    • Hou, J.1    Lin, L.2    Zhou, W.3
  • 31
    • 84858195484 scopus 로고    scopus 로고
    • Liver-specific microRNA-122: biogenesis and function
    • Jopling C. Liver-specific microRNA-122: biogenesis and function. RNA Biol 2012; 9(2): 137–142.
    • (2012) RNA Biol , vol.9 , Issue.2 , pp. 137-142
    • Jopling, C.1
  • 32
    • 84922244588 scopus 로고    scopus 로고
    • miR-122 – a key factor and therapeutic target in liver disease
    • Bandiera S, Pfeffer S, Baumert TF, Zeisel MB. miR-122 – a key factor and therapeutic target in liver disease. J Hepatol 2015; 62(2): 448–457.
    • (2015) J Hepatol , vol.62 , Issue.2 , pp. 448-457
    • Bandiera, S.1    Pfeffer, S.2    Baumert, T.F.3    Zeisel, M.B.4
  • 33
    • 84954467693 scopus 로고    scopus 로고
    • Addressing bias in small RNA library preparation for sequencing: a new protocol recovers microRNAs that evade capture by current methods
    • Baran-Gale J, Kurtz CL, Erdos MR, et al. Addressing bias in small RNA library preparation for sequencing: a new protocol recovers microRNAs that evade capture by current methods. Front Genet 2015; 6: 352.
    • (2015) Front Genet , vol.6 , pp. 352
    • Baran-Gale, J.1    Kurtz, C.L.2    Erdos, M.R.3
  • 34
    • 84926624009 scopus 로고    scopus 로고
    • Small tRNA-derived RNAs are increased and more abundant than microRNAs in chronic hepatitis B and C
    • Selitsky SR, Baran-Gale J, Honda M et al. Small tRNA-derived RNAs are increased and more abundant than microRNAs in chronic hepatitis B and C. Sci Rep 2015; 5: 7675.
    • (2015) Sci Rep , vol.5 , pp. 7675
    • Selitsky, S.R.1    Baran-Gale, J.2    Honda, M.3
  • 35
    • 84885155219 scopus 로고    scopus 로고
    • microRNA-122 abundance in hepatocellular carcinoma and non-tumor liver tissue from Japanese patients with persistent HCV versus HBV infection
    • Spaniel C, Honda M, Selitsky SR et al. microRNA-122 abundance in hepatocellular carcinoma and non-tumor liver tissue from Japanese patients with persistent HCV versus HBV infection. PLoS One 2013; 8(10): e76867.
    • (2013) PLoS One , vol.8 , Issue.10
    • Spaniel, C.1    Honda, M.2    Selitsky, S.R.3
  • 36
    • 84900312836 scopus 로고    scopus 로고
    • Post-transcriptional regulation of interferons and their signaling pathways
    • Savan R. Post-transcriptional regulation of interferons and their signaling pathways. J Interferon Cytokine Res 2014; 34(5): 318–329.
    • (2014) J Interferon Cytokine Res , vol.34 , Issue.5 , pp. 318-329
    • Savan, R.1
  • 37
    • 84890951661 scopus 로고    scopus 로고
    • The favorable IFNL3 genotype escapes mRNA decay mediated by AU-rich elements and hepatitis C virus-induced microRNAs
    • McFarland AP, Horner SM, Jarret A et al. The favorable IFNL3 genotype escapes mRNA decay mediated by AU-rich elements and hepatitis C virus-induced microRNAs. Nat Immunol 2014; 15(1): 72–79.
    • (2014) Nat Immunol , vol.15 , Issue.1 , pp. 72-79
    • McFarland, A.P.1    Horner, S.M.2    Jarret, A.3
  • 38
    • 84873896374 scopus 로고    scopus 로고
    • MicroRNA expression profiling in HCV-infected human hepatoma cells identifies potential anti-viral targets induced by interferon-alpha
    • Zhang X, Daucher M, Armistead D, Russell R, Kottilil S. MicroRNA expression profiling in HCV-infected human hepatoma cells identifies potential anti-viral targets induced by interferon-alpha. PLoS One 2013; 8(2): e55733.
    • (2013) PLoS One , vol.8 , Issue.2
    • Zhang, X.1    Daucher, M.2    Armistead, D.3    Russell, R.4    Kottilil, S.5
  • 39
    • 84866144505 scopus 로고    scopus 로고
    • Hepatitis C virus infection modulates expression of interferon stimulatory gene IFITM1 by upregulating miR-130A
    • Bhanja Chowdhury J, Shrivastava S, Steele R, Di Bisceglie AM, Ray R, Ray RB. Hepatitis C virus infection modulates expression of interferon stimulatory gene IFITM1 by upregulating miR-130A. J Virol 2012; 86(18): 10221–10225.
    • (2012) J Virol , vol.86 , Issue.18 , pp. 10221-10225
    • Bhanja, C.J.1    Shrivastava, S.2    Steele, R.3    Di, B.A.M.4    Ray, R.5    Ray, R.B.6
  • 40
    • 84901604742 scopus 로고    scopus 로고
    • The role of microRNAs in hepatitis C virus replication and related liver diseases
    • Lee CH, Kim JH, Lee SW. The role of microRNAs in hepatitis C virus replication and related liver diseases. J Microbiol 2014; 52(6): 445–451.
    • (2014) J Microbiol , vol.52 , Issue.6 , pp. 445-451
    • Lee, C.H.1    Kim, J.H.2    Lee, S.W.3
  • 42
    • 84885787867 scopus 로고    scopus 로고
    • Hepatitis C virus infection, microRNA and liver disease progression
    • Shrivastava S, Mukherjee A, Ray RB. Hepatitis C virus infection, microRNA and liver disease progression. World J Hepatol 2013; 5(9): 479–486.
    • (2013) World J Hepatol , vol.5 , Issue.9 , pp. 479-486
    • Shrivastava, S.1    Mukherjee, A.2    Ray, R.B.3
  • 43
    • 84876858736 scopus 로고    scopus 로고
    • HCV-induced miR-21 contributes to evasion of host immune system by targeting MyD88 and IRAK1
    • Chen Y, Chen J, Wang H et al. HCV-induced miR-21 contributes to evasion of host immune system by targeting MyD88 and IRAK1. PLoS Pathog 2013; 9(4): e1003248.
    • (2013) PLoS Pathog , vol.9 , Issue.4
    • Chen, Y.1    Chen, J.2    Wang, H.3
  • 45
    • 35349009932 scopus 로고    scopus 로고
    • Interferon modulation of cellular microRNAs as an antiviral mechanism
    • Pedersen IM, Cheng G, Wieland S et al. Interferon modulation of cellular microRNAs as an antiviral mechanism. Nature 2007; 449(7164): 919–922.
    • (2007) Nature , vol.449 , Issue.7164 , pp. 919-922
    • Pedersen, I.M.1    Cheng, G.2    Wieland, S.3
  • 46
    • 84864368867 scopus 로고    scopus 로고
    • Let-7b is a novel regulator of hepatitis C virus replication
    • Cheng JC, Yeh YJ, Tseng CP et al. Let-7b is a novel regulator of hepatitis C virus replication. Cell Mol Life Sci 2012; 69(15): 2621–2633.
    • (2012) Cell Mol Life Sci , vol.69 , Issue.15 , pp. 2621-2633
    • Cheng, J.C.1    Yeh, Y.J.2    Tseng, C.P.3
  • 47
    • 59349098653 scopus 로고    scopus 로고
    • Regulation of the hepatitis C virus genome replication by miR-199a
    • Murakami Y, Aly HH, Tajima A, Inoue I, Shimotohno K. Regulation of the hepatitis C virus genome replication by miR-199a. J Hepatol 2009; 50(3): 453–460.
    • (2009) J Hepatol , vol.50 , Issue.3 , pp. 453-460
    • Murakami, Y.1    Aly, H.H.2    Tajima, A.3    Inoue, I.4    Shimotohno, K.5
  • 48
    • 79957515102 scopus 로고    scopus 로고
    • Hepatitis C virus infection and hepatic stellate cell activation downregulate miR-29: miR-29 overexpression reduces hepatitis C viral abundance in culture
    • Bandyopadhyay S, Friedman RC, Marquez RT et al. Hepatitis C virus infection and hepatic stellate cell activation downregulate miR-29: miR-29 overexpression reduces hepatitis C viral abundance in culture. J Infect Dis 2011; 203(12): 1753–1762.
    • (2011) J Infect Dis , vol.203 , Issue.12 , pp. 1753-1762
    • Bandyopadhyay, S.1    Friedman, R.C.2    Marquez, R.T.3
  • 49
    • 84868192318 scopus 로고    scopus 로고
    • Hepatitis C virus-induced up-regulation of microRNA-155 promotes hepatocarcinogenesis by activating Wnt signaling
    • Zhang Y, Wei W, Cheng N et al. Hepatitis C virus-induced up-regulation of microRNA-155 promotes hepatocarcinogenesis by activating Wnt signaling. Hepatology 2012; 56(5): 1631–1640.
    • (2012) Hepatology , vol.56 , Issue.5 , pp. 1631-1640
    • Zhang, Y.1    Wei, W.2    Cheng, N.3
  • 50
    • 84943613789 scopus 로고    scopus 로고
    • Expression of interferon lambda 4 is associated with reduced proliferation and increased cell death in human hepatic cells
    • Onabajo OO, Porter-Gill P, Paquin A et al. Expression of interferon lambda 4 is associated with reduced proliferation and increased cell death in human hepatic cells. J Interferon Cytokine Res 2015; 35(11): 888–900.
    • (2015) J Interferon Cytokine Res , vol.35 , Issue.11 , pp. 888-900
    • Onabajo, O.O.1    Porter-Gill, P.2    Paquin, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.